@article{MTMT:34825468, title = {Incident Cancer Risk in Patients with Incident Type 2 Diabetes Mellitus in Hungary (Part 1)}, url = {https://m2.mtmt.hu/api/publication/34825468}, author = {Abonyi-Tóth, Zsolt and Rokszin, György Aurél and Bajcsayné Fábián, Ibolya and Kiss, Zoltán and Jermendy, György and Kempler, Péter and Lengyel, Csaba Attila and Wittmann, István and Molnár, Gergő Attila and Sütő, Gábor}, journal-iso = {CANCERS}, journal = {CANCERS}, volume = {16}, unique-id = {34825468}, abstract = {Abstract (1) Background: Patients with type 2 diabetes mellitus (T2DM) are at higher risk of cancer but how these two diseases associate is still debated. The goal of this study was the assessment of the overall incidence of cancer among patients with newly diagnosed T2DM in Hungary. (2) Methods: A nationwide, retrospective, longitudinal study was performed using a Hungarian database. After exclusion of cases of age < 18 years, with gestational diabetes, with polycystic ovary syndrome, and with type 1 and prevalent type 2 diabetes mellitus, the incident T2DM (approx. 50,000 cases yearly) and for comparison, the diabetes-free Hungarian adult population (approx. 7,000,000 cases yearly) was included in the study. The primary endpoints were the overall and site-specific incidence and annual percentage change of the incidence of cancer in both populations. (3) Results: The overall incidence of cancer in patients amounted to 29.4/1000 and 6.6/1000 with or without T2DM, respectively, and the OR (95%CI) of cancer of the T2DM group was 4.32 (4.14–4.53), p < 0.0001. The risk of having cancer was age dependent. The incidence of cancer was declining in the non-diabetic but was unchanged in the T2DM population. The average lag time of diagnosing cancer after the detection of T2DM was 3.86 months. (4) Conclusions: Incident T2DM is associated with a significantly higher overall risk of incident cancer, with a reverse correlation of age. Newly registered T2DM patients were suggested to be screened for cancer within 6 months.}, year = {2024}, eissn = {2072-6694}, orcid-numbers = {Abonyi-Tóth, Zsolt/0000-0002-5585-3313; Kiss, Zoltán/0000-0002-4752-8529; Kempler, Péter/0000-0002-6072-8832; Lengyel, Csaba Attila/0000-0002-0434-0067; Molnár, Gergő Attila/0000-0001-6052-5907} } @article{MTMT:34824725, title = {Trends and regional differences in antidiabetic medication use: a nationwide retrospective observational study}, url = {https://m2.mtmt.hu/api/publication/34824725}, author = {Csatordai, Márta and Benkő, Ria and Matuz, Mária and Engi, Zsófia and Csupor, Dezső and Lengyel, Csaba Attila and Doró, Péter}, doi = {10.1186/s13098-024-01334-8}, journal-iso = {DIABETOL METAB SYNDR}, journal = {DIABETOLOGY AND METABOLIC SYNDROME}, volume = {16}, unique-id = {34824725}, issn = {1758-5996}, year = {2024}, eissn = {1758-5996}, orcid-numbers = {Benkő, Ria/0000-0002-8009-8962; Matuz, Mária/0000-0002-7877-2399; Csupor, Dezső/0000-0002-4088-3333; Lengyel, Csaba Attila/0000-0002-0434-0067; Doró, Péter/0000-0001-7784-6010} } @article{MTMT:34778284, title = {Autonomic function and specific right atrial functions - Is there a relationship? Correlations from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study}, url = {https://m2.mtmt.hu/api/publication/34778284}, author = {Nemes, Attila and Kormányos, Árpád and Orosz, Andrea and Ambrus, Nóra and Várkonyi, Tamás and Lengyel, Csaba Attila}, doi = {10.1002/jcu.23672}, journal-iso = {J CLIN ULTRASOUND}, journal = {JOURNAL OF CLINICAL ULTRASOUND}, unique-id = {34778284}, issn = {0091-2751}, abstract = {Similarly to the ventricles, the atria are under sympathetic/parasympathetic neural regulation. Accordingly, correlations were investigated between Ewing's standard cardiovascular reflex tests (SCRTs) and three-dimensional speckle-tracking echocardiography (3DSTE)-derived right atrial (RA) volumes and strains in healthy subjects.The study comprised 45 healthy adults, but 5 subjects were excluded due to inferior image quality for 3DSTE-derived RA assessments. The remaining 40 individuals being in sinus rhythm had a mean age of 35.1 ± 3.5 years (20 men). Two-dimensional, Doppler, 3DSTE and SCRTs were performed in all cases.RA maximum volume and total and passive RA stroke volumes correlated with the Valsalva ratio. Active RA stroke volume and emptying fraction showed correlations with 30/15 ratio. Peak global and mean segmental RA circumferential (CS) and longitudinal strains (LS) showed correlation with the Valsalva ratio. At atrial contraction, global RA-LS and mean segmental RA-CS showed correlations with the Valsalva ratio. Moreover, mean segmental RA-CS correlated with 30/15 ratio and mean segmental RA radial strain showed correlations with systolic blood pressure in response to standing. Autonomic neuropathy score correlated with peak global RA-LS.Autonomic function parameters have significant associations with specific RA functions in healthy adults, making the latter possible indicators of autonomic dysregulation.}, keywords = {Echocardiography; Correlation; three-dimensional; Autonomic; Speckle-tracking; Right atrial}, year = {2024}, eissn = {1097-0096}, orcid-numbers = {Nemes, Attila/0000-0002-7570-6214; Kormányos, Árpád/0000-0002-7052-2184; Várkonyi, Tamás/0000-0001-6833-3563; Lengyel, Csaba Attila/0000-0002-0434-0067} } @{MTMT:34768899, title = {The Relationship between Tricuspid Annular Longitudinal and Sphincter-Like Features of Its Function in Healthy Adults: Insights from the MAGYAR-Healthy Study}, url = {https://m2.mtmt.hu/api/publication/34768899}, author = {Nemes, Attila and Rácz, Gergely and Kormányos, Árpád and Ruzsa, Zoltán and Achim, Alexandru and Lengyel, Csaba Attila}, booktitle = {Cardiovascular Diseases: From Basic Research to Clinical Application}, unique-id = {34768899}, year = {2024}, pages = {155-164}, orcid-numbers = {Nemes, Attila/0000-0002-7570-6214; Kormányos, Árpád/0000-0002-7052-2184; Ruzsa, Zoltán/0000-0002-2474-5723; Lengyel, Csaba Attila/0000-0002-0434-0067} } @article{MTMT:34557988, title = {Right Ventricular Longitudinal Shortening is not Associated with Left Ventricular Rotational Mechanics in Healthy Adults - Insights from the Three-dimensional Speckle-tracking Echocardiographic MAGYAR-Healthy Study}, url = {https://m2.mtmt.hu/api/publication/34557988}, author = {Nemes, Attila and Kormányos, Árpád and Ruzsa, Zoltán and Achim, Alexandru and Ambrus, Nóra and Lengyel, Csaba Attila}, doi = {10.31083/j.rcm2502053}, journal-iso = {REV CARDIOVASC MED}, journal = {REVIEWS IN CARDIOVASCULAR MEDICINE}, volume = {25}, unique-id = {34557988}, issn = {1530-6550}, year = {2024}, eissn = {2153-8174}, orcid-numbers = {Nemes, Attila/0000-0002-7570-6214; Kormányos, Árpád/0000-0002-7052-2184; Ruzsa, Zoltán/0000-0002-2474-5723; Lengyel, Csaba Attila/0000-0002-0434-0067} } @article{MTMT:34521238, title = {D-dimer levels to exclude pulmonary embolism and reduce the need for CT angiography in COVID-19 in an outpatient population}, url = {https://m2.mtmt.hu/api/publication/34521238}, author = {Kovács, Anita and Hantosi, Dóra and Szabó, Nikoletta and Letoha, Annamária and Lengyel, Csaba Attila and Földesi, Imre and Burián, Katalin and Palkó, András and Veréb, Dániel and Kincses, Zsigmond Tamás}, doi = {10.1371/journal.pone.0297023}, journal-iso = {PLOS ONE}, journal = {PLOS ONE}, volume = {19}, unique-id = {34521238}, issn = {1932-6203}, year = {2024}, eissn = {1932-6203}, orcid-numbers = {Lengyel, Csaba Attila/0000-0002-0434-0067; Földesi, Imre/0000-0002-3329-8136; Burián, Katalin/0000-0003-1300-2374; Palkó, András/0000-0002-5370-6934; Veréb, Dániel/0000-0003-2077-5252; Kincses, Zsigmond Tamás/0000-0002-1442-4475} } @article{MTMT:34400260, title = {Correlations between vegetative autonomic function and specific left atrial functions in healthy adults: Insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study}, url = {https://m2.mtmt.hu/api/publication/34400260}, author = {Nemes, Attila and Kormányos, Árpád and Orosz, Andrea and Ambrus, Nóra and Várkonyi, Tamás and Lengyel, Csaba Attila}, doi = {10.1002/jcu.23603}, journal-iso = {J CLIN ULTRASOUND}, journal = {JOURNAL OF CLINICAL ULTRASOUND}, volume = {52}, unique-id = {34400260}, issn = {0091-2751}, abstract = {The functioning of the left atrium (LA) is partly controlled by the neural system. It was purposed to evaluate correlations between the result of Ewing's 5 standard cardiovascular reflex tests (SCRTs) characterizing autonomic function and LA volumetric and functional features as assessed by three-dimensional speckle-tracking echocardiography (3DSTE) in healthy individuals.The current study comprised 18 healthy volunteers being in sinus rhythm (mean age: 35 ± 12 years, 10 men). Measurement of blood pressure, ECG, 5 SCRTs, two-dimensional Doppler echocardiography and 3DSTE were performed. These parameters were in normal ranges in all cases.From LA volumetric parameters, only systolic total atrial emptying fraction (r = 0.559, p = 0.037) and early diastolic passive atrial emptying fraction (r = 0.539, p = 0.047) correlated with systolic blood pressure response to standing representing sympathetic autonomic function. From LA strains, peak mean segmental LA radial strain (RS) (r = -0.532, p = 0.050), global and mean segmental LA circumferential strain (CS) (r = 0.662, p = 0.010 and r = 0.635, p = 0.015, respectively) representing systolic LA function correlated with Valsalva ratio representing parasympathetic autonomic function. Global LA-RS (r = -0.713, p = 0.040) and LA-CS (r = 0.657, p = 0.011) and mean segmental LA-CS (r = 0.723, p = 0.003) at atrial contraction representing end-diastolic atrial contraction showed correlations with Valsalva ratio, as well. Peak global and mean segmental LA-CS (r = 0.532, p = 0.050 and r = 0.530, p = 0.050) and the same strains at atrial contraction (r = 0.704, p = 0.005 and r = 0.690, p = 0.006) representing systolic function and end-diastolic atrial contraction correlated with systolic blood pressure response to standing representing both parasympathetic and sympathetic autonomic functions.Significant correlations between features of vegetative autonomic function represented by Ewing's 5 SCRTs and specific LA functions represented by 3DSTE-derived LA volume-based functional properties and strains could be demonstrated in healthy adults.}, keywords = {Echocardiography; Correlation; three-dimensional; Autonomic; Speckle-tracking; LEFT ATRIAL}, year = {2024}, eissn = {1097-0096}, pages = {178-185}, orcid-numbers = {Nemes, Attila/0000-0002-7570-6214; Kormányos, Árpád/0000-0002-7052-2184; Várkonyi, Tamás/0000-0001-6833-3563; Lengyel, Csaba Attila/0000-0002-0434-0067} } @article{MTMT:34560639, title = {SGLT2-GÁTLÓ DAPAGLIFLOZIN EREDMÉNYES ALKALMAZÁSA NEPHROSIS SZINDRÓMÁVAL JÁRÓ, SZÖVETTANILAG IGAZOLT DIABETESES VESEBETEGSÉGBEN}, url = {https://m2.mtmt.hu/api/publication/34560639}, author = {Fejes, Imola and Bajcsi, Dóra and Czakó, László and Turkevi-Nagy, Sándor and Iványi, Béla and Ábrahám, György and Várkonyi, Tamás and Lengyel, Csaba Attila and Légrády, Péter}, journal-iso = {MBA}, journal = {MAGYAR BELORVOSI ARCHIVUM}, volume = {76}, unique-id = {34560639}, issn = {0133-5464}, year = {2023}, pages = {306-306}, orcid-numbers = {Czakó, László/0000-0002-6331-0802; Ábrahám, György/0000-0002-2272-2317; Várkonyi, Tamás/0000-0001-6833-3563; Lengyel, Csaba Attila/0000-0002-0434-0067} } @article{MTMT:34559525, title = {A NÖVEKEDÉSI HORMON HATÁSA A SZÍV FIZIOLÓGIÁJÁRA}, url = {https://m2.mtmt.hu/api/publication/34559525}, author = {Christofi, A and Kormányos, Árpád and Kalapos, Anita and Domsik, Péter and Gyenes, Nándor and Ambrus, Nóra and Gavallér, Edit Henriette and Csajbók, Éva and Julesz, János and Forster, Tamás and Csanády, Miklós and Horváth, Á and Lengyel, Csaba Attila and Nemes, Attila and Valkusz, Zsuzsanna}, journal-iso = {MBA}, journal = {MAGYAR BELORVOSI ARCHIVUM}, volume = {76}, unique-id = {34559525}, issn = {0133-5464}, year = {2023}, pages = {303-303}, orcid-numbers = {Kormányos, Árpád/0000-0002-7052-2184; Forster, Tamás/0000-0003-3311-6475; Lengyel, Csaba Attila/0000-0002-0434-0067; Nemes, Attila/0000-0002-7570-6214; Valkusz, Zsuzsanna/0000-0003-1928-6160} } @article{MTMT:34519512, title = {Három hónapos edzésprogram javítja a kardiovaszkuláris autonóm funkciót a metabolikus szindrómás páciensekben}, url = {https://m2.mtmt.hu/api/publication/34519512}, author = {Vágvölgyi, Anna and Nyiraty, Szabolcs and Máthéné, Köteless É and Korom, A and Ábrahám, Erzsébet Judit and Barnai, Mária and Szűcs, Mónika and Orosz, Andrea and Nemes, Attila and Baczkó, István and Kempler, Péter and Várkonyi, Tamás and Kósa, István and Lengyel, Csaba Attila}, journal-iso = {MBA}, journal = {MAGYAR BELORVOSI ARCHIVUM}, volume = {76}, unique-id = {34519512}, issn = {0133-5464}, year = {2023}, pages = {338-339}, orcid-numbers = {Vágvölgyi, Anna/0000-0002-8810-700X; Barnai, Mária/0000-0003-2184-2701; Szűcs, Mónika/0000-0002-8791-9452; Nemes, Attila/0000-0002-7570-6214; Baczkó, István/0000-0002-9588-0797; Kempler, Péter/0000-0002-6072-8832; Várkonyi, Tamás/0000-0001-6833-3563; Kósa, István/0000-0002-8805-4307; Lengyel, Csaba Attila/0000-0002-0434-0067} }