TY - JOUR AU - Juvancz, Zoltán AU - Bodáné Kendrovics, Rita AU - Ágoston, Csaba AU - Maklari, Dora AU - Voller, Csanad Csaba AU - Kaleta, Zoltán TI - Chiral Separation of Mandelic Acid Derivatives Using Various Permethylated Cyclodextrin Selectors Containing Stationary Phases in GC JF - MOLECULES J2 - MOLECULES VL - 30 PY - 2025 IS - 3 PG - 16 SN - 1431-5157 DO - 10.3390/molecules30030451 UR - https://m2.mtmt.hu/api/publication/35781947 ID - 35781947 AB - A good chiral separation usually results in a trial-and-error process; however, through systematic studies, certain principles can be established to correlate structure with chiral selectivity. These principles can then be applied to other chiral separations, reducing the time of developing chiral selective analytical methods. Using the model compounds, the established principles can be applied to a wider range of compounds. In this study, mandelic acid and its substituted derivatives were selected as model compounds to establish transferable rules. The chiral selectivity of 13 compounds was measured on various permethylated cyclodextrin selectors. Comparing the chiral selectivity of permethylated cyclodextrins with different ring sizes (alpha, beta, and gamma) provides further insight into the role of inclusion in the chiral selectivity of the cyclodextrin-based stationary phases. Different derivatives of acidic and hydroxyl functions of mandelic acids were tested. Ring- and alkyl-substituted mandelic acid enantiomeric pairs were also tested. By using these compounds, the role of hydrogen donor-acceptor interactions and dipole-dipole interactions and inclusions in chiral recognition processes were investigated. The chiral selectivity values were measured and extrapolated to the same temperature, for the sake of the comparison. Several general tendencies were concluded, which can be used for chiral separation of other enantiomer pairs. LA - English DB - MTMT ER - TY - JOUR AU - Hunyadi, Csaba AU - Szemán, Julianna AU - Juvancz, Zoltán AU - Mörtl, Mária AU - Székács, András AU - Kaleta, Zoltán TI - Chiral separation of conazole pesticides using supercritical fluid chromatography JF - INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY J2 - INT J ENVIRON AN CH VL - 104 PY - 2024 IS - 17 SP - 5012 EP - 5022 PG - 11 SN - 0306-7319 DO - 10.1080/03067319.2022.2115904 UR - https://m2.mtmt.hu/api/publication/33088474 ID - 33088474 N1 - Published online on: 31 Aug 2022 LA - English DB - MTMT ER - TY - JOUR AU - Juvancz, Zoltán AU - Bodáné Kendrovics, Rita AU - Ágoston, Csaba AU - Czegledi, B. AU - Kaleta, Zoltán AU - Jicsinszky, L. AU - Riszter, Gergő Attila TI - Chiral Selectivities of Permethylated α-, β-, and γ-Cyclodextrins Containing Gas Chromatographic Stationary Phases towards Ibuprofen and Its Derivatives JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 25 PY - 2024 IS - 14 PG - 11 SN - 1661-6596 DO - 10.3390/ijms25147802 UR - https://m2.mtmt.hu/api/publication/35159930 ID - 35159930 N1 - Rejtő Sándor Faculty of Light Industry and Environmental Engineering, Institute of Environmental Engineering and Natural Science, Óbuda University, Doberdó út 6, Budapest, H-1034, Hungary Department of Organic Chemistry, Semmelweis University, Hőgyes Endre Street 7, Budapest, H-1092, Hungary Dipartimento di Scienza e Tecnologia del Farmaco, University of Turin, Via P. Giuria, 9, Turin, 10125, Italy Artificial Transporters Research Group, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok Körútja 2, Budapest, H-1117, Hungary Export Date: 9 October 2024 Correspondence Address: Juvancz, Z.; Rejtő Sándor Faculty of Light Industry and Environmental Engineering, Doberdó út 6, Hungary; email: juvancz.zoltan@uni-obuda.hu Correspondence Address: Kaleta, Z.; Department of Organic Chemistry, Hőgyes Endre Street 7, Hungary; email: kaleta.zoltan@semmelweis.hu LA - English DB - MTMT ER - TY - JOUR AU - Repassy, Levente AU - Juvancz, Zoltán AU - Bodáné Kendrovics, Rita AU - Kaleta, Zoltán AU - Hunyadi, Csaba AU - Riszter, Gergő Attila TI - Structure–Chiral Selectivity Relationships of Various Mandelic Acid Derivatives on Octakis 2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl-gamma-cyclodextrin Containing Gas Chromatographic Stationary JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 24 PY - 2023 IS - 20 PG - 16 SN - 1661-6596 DO - 10.3390/ijms242015051 UR - https://m2.mtmt.hu/api/publication/34189557 ID - 34189557 AB - Frequently, a good chiral separation is the result of long trial and error processes. The three-point interaction mechanisms require the fair geometrical fitting and functional group compatibility of the interacting groups. Structure–chiral selectivity correlations are guidelines that can be established via trough systematic studies using model compounds. The enantiorecognition of the test compounds was studied on an octakis 2,3-Di-O-acetyl-6-O-tert-butyldimethylsilyl-gamma-cyclodextrin (TBDMSDAGCD) chiral selector. In our work, mandelic acid and its variously substituted compounds were used as model compounds to establish adaptable rules for other enantiomeric pairs. The mandelic acid and its modified compounds were altered at both their carboxyl and hydroxyl positions to test the key interaction forces of the chiral recognition processes. Ring- and alkyl-substituted mandelic acid derivatives were also used in our experiments. The chiral selectivity values of 20 test compounds were measured and extrapolated to 100 °C. The hydrogen donor abilities of test compounds improved their chiral selectivities. The inclusion phenomenon also played a role in chiral recognition processes in several cases. Enantiomer elution reversals were observed for different derivatives of hydroxyl groups, providing evidence for the multimodal character of the selector. The results of our research can serve as guidelines to achieve appropriate chiral separation for other enantiomeric pairs. LA - English DB - MTMT ER - TY - CHAP AU - Juvancz, Zoltán AU - Bodáné Kendrovics, Rita AU - Zita, LACZKÓ ED - Bayoumi Hamuda, Hosam TI - CHIRAL SEPARATIONS OF PHYRETROIC ACIDS USING CYCLODEXTRIN SELECTORS T2 - Proceedings of VI. International Symposium on Biosphere & Environmental Safety PB - Óbudai Egyetem CY - Budapest SN - 9789634492856 PY - 2022 SP - 357 EP - 365 PG - 9 UR - https://m2.mtmt.hu/api/publication/33089206 ID - 33089206 LA - English DB - MTMT ER - TY - JOUR AU - Juvancz, Zoltán AU - László, Tolner TI - Combination of energy production and plastic waste management JF - INTERNATIONAL JOURNAL OF LATEST RESEARCH IN ENGINEERING AND TECHNOLOGY J2 - IJLRET VL - & PY - 2022 SP - 1 EP - 7 PG - 7 SN - 2454-5031 UR - https://m2.mtmt.hu/api/publication/33124697 ID - 33124697 LA - English DB - MTMT ER - TY - CHAP AU - Bodáné Kendrovics, Rita AU - Juvancz, Zoltán ED - Mitryasova, Olena TI - Chapter VII. T2 - New Challenges of the Century: Textbook PB - Bona CY - Lviv SN - 9786178097011 PY - 2022 SP - 237 EP - 250 PG - 14 UR - https://m2.mtmt.hu/api/publication/33124704 ID - 33124704 LA - English DB - MTMT ER - TY - CHAP AU - RÉPÁSSY, Levente AU - Juvancz, Zoltán AU - Bodáné Kendrovics, Rita ED - Koltai, László TI - KÖRNYEZETI SZEMPONTBÓL FONTOS MANDULASAV-SZÁRMAZÉKOK ENANTIOMER SZELEKTÍV GÁZKROMATOGRÁFIÁS ELVÁLASZTÁSA GAMMA CIKLODEXTRIN SZELEKTORON T2 - REJTŐ ’50’ JUBILEUMI KONFERENCIA PB - Óbudai Egyetem CY - Budapest SN - 9789634493082 PY - 2022 SP - 250 EP - 259 PG - 10 UR - https://m2.mtmt.hu/api/publication/33251547 ID - 33251547 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Juvancz, Zoltán AU - Bodáné Kendrovics, Rita AU - Laczkó, Zita AU - Iványi, Róbert AU - Varga, Erzsébet TI - Chiral Separations of Pyrethroic Acids Using Cyclodextrin Selectors JF - MOLECULES J2 - MOLECULES VL - 27 PY - 2022 IS - 24 SN - 1431-5157 DO - 10.3390/molecules27248718 UR - https://m2.mtmt.hu/api/publication/33318067 ID - 33318067 AB - Pyrethroid insecticides are broadly used. They have low toxicity for warm-blooded living creatures, but high toxicity for both insects and fish. Therefore, it is important to reduce the environmental impact of pyrethroids. Pyrethroic acids are chiral compounds. An effective way to decrease pollution is to use enantio-pure insecticide products instead of their racemic mixtures. Enantiomer-pure products require enantiomer selective synthesis and analysis. The chiral selective analysis of pyrethroic acids (an intermediate of pyrethroids) is also important in terms of process control and from the point of view of their degradation metabolism in the environment. This study used various enantiomeric selective chromatographic methods for the separation of different pyrethroic acids, including gas chromatography, supercritical fluid chromatography and capillary electrophoresis. Systematic experiments were conducted to find the optimum conditions for their chiral separation. The employed enantio-selective agents were cyclodextrin derivatives with different ring sizes and substitution patterns. The β-cyclodextrin proved to be excellent for the chiral separation of these acids. The different chiral recognition mechanisms were established using different ring-sized cyclodextrins. The results of these systematic studies demonstrated the correlations of the chiral selectivity features of selectors and the structures of analytes. LA - English DB - MTMT ER - TY - JOUR AU - Juvancz, Zoltán AU - Bodáné Kendrovics, Rita AU - Szente, Lajos AU - Maklári, Dóra TI - Cyclodextrins as Dominant Chiral Selective Agents in the Capillary Separation Techniques JF - PERIODICA POLYTECHNICA-CHEMICAL ENGINEERING J2 - PERIOD POLYTECH CHEM ENG VL - 65 PY - 2021 IS - 4 SP - 580 EP - 594 PG - 15 SN - 0324-5853 DO - 10.3311/PPch.18067 UR - https://m2.mtmt.hu/api/publication/32173480 ID - 32173480 LA - English DB - MTMT ER -