@article{MTMT:35655586, title = {A systematic review of liposomal nanofibrous scaffolds as a drug delivery system: a decade of progress in controlled release and therapeutic efficacy}, url = {https://m2.mtmt.hu/api/publication/35655586}, author = {Abboud, Houssam and Zelkó, Romána and Nochta-Kazsoki, Adrienn Katalin}, doi = {10.1080/10717544.2024.2445259}, journal-iso = {DRUG DELIV}, journal = {DRUG DELIVERY : JOURNAL OF DELIVERY AND TARGETING OF THERAPEUTIC AGENTS}, volume = {32}, unique-id = {35655586}, issn = {1071-7544}, year = {2025}, eissn = {1521-0464}, orcid-numbers = {Abboud, Houssam/0009-0001-5833-6506; Zelkó, Romána/0000-0002-5419-9137; Nochta-Kazsoki, Adrienn Katalin/0000-0002-0611-3124} } @CONFERENCE{MTMT:35959609, title = {A gyógyszerészek szerepe az idős betegek sztatinterápiás adherenciájának javításában: egy randomizált, kontrollált vizsgálat}, url = {https://m2.mtmt.hu/api/publication/35959609}, author = {Artner, Anna and Eőry, Ajándék and Hankó, Balázs and Torzsa, Péter and Zelkó, Romána}, booktitle = {CSALÁDORVOS KUTATÓK ORSZÁGOS SZERVEZETE - XXIII. Kongresszus}, unique-id = {35959609}, year = {2025}, pages = {n/a}, orcid-numbers = {Artner, Anna/0009-0005-8541-7925; Eőry, Ajándék/0000-0002-4434-1339; Hankó, Balázs/0000-0002-1953-2838; Torzsa, Péter/0000-0002-8148-4961; Zelkó, Romána/0000-0002-5419-9137} } @book{MTMT:36012044, title = {TOPICAL AMLODIPINE SALTS FOR THE TREATMENT OF ANORECTAL DISEASES}, url = {https://m2.mtmt.hu/api/publication/36012044}, author = {László, Ritter and László, Hornok and Mátyus, Péter and Zelkó, Romána and Andrea, Ujhelyi and Richárd, Balázs Kárpáti and Tamás, Solymosi and Hristos, Glavinas}, unique-id = {36012044}, year = {2025}, orcid-numbers = {Mátyus, Péter/0000-0003-3963-9445; Zelkó, Romána/0000-0002-5419-9137} } @misc{MTMT:36112298, title = {Development of a Multifunctional Nanofibrous Patch for Oral Aphthae Treatment.}, url = {https://m2.mtmt.hu/api/publication/36112298}, author = {Nochta-Kazsoki, Adrienn Katalin and Abboud, Houssam and Zelkó, Romána}, unique-id = {36112298}, year = {2025}, orcid-numbers = {Nochta-Kazsoki, Adrienn Katalin/0000-0002-0611-3124; Abboud, Houssam/0009-0001-5833-6506; Zelkó, Romána/0000-0002-5419-9137} } @article{MTMT:36215710, title = {Evaluation of 3D-Printed Balls with Photopolymer Resin as Grinding Medium Used to Alternatively Reduce Warmup During Dry Milling}, url = {https://m2.mtmt.hu/api/publication/36215710}, author = {Borbás, Bence and Kohod, Z. and Kállai-Szabó, Nikolett and Basa, Bálint and Lengyel, Miléna and Zelkó, Romána and Antal, István}, doi = {10.3390/polym17131795}, journal-iso = {POLYMERS-BASEL}, journal = {POLYMERS}, volume = {17}, unique-id = {36215710}, year = {2025}, eissn = {2073-4360}, orcid-numbers = {Borbás, Bence/0000-0002-4892-4347; Kállai-Szabó, Nikolett/0000-0002-8164-3993; Basa, Bálint/0000-0003-4546-1727; Lengyel, Miléna/0000-0001-8865-054X; Zelkó, Romána/0000-0002-5419-9137; Antal, István/0000-0002-5434-201X} } @article{MTMT:36216612, title = {Development of Low-Dose Disulfiram Rectal Suppository Intended for Application in Post-Treatment Lyme Disease Syndrome}, url = {https://m2.mtmt.hu/api/publication/36216612}, author = {Benkő, Beáta Mária and Szabó, B.-I. and Kádár, Szabina and Szabó, Edina and Tóth, Gergő and Szente, Lajos and Tonka-Nagy, P. and Zelkó, Romána and Sebe, István}, doi = {10.3390/pharmaceutics17070849}, journal-iso = {PHARMACEUTICS}, journal = {PHARMACEUTICS}, volume = {17}, unique-id = {36216612}, year = {2025}, eissn = {1999-4923}, orcid-numbers = {Benkő, Beáta Mária/0000-0002-3608-6219; Szabó, Edina/0000-0001-9616-5122; Tóth, Gergő/0000-0001-5341-319X; Zelkó, Romána/0000-0002-5419-9137; Sebe, István/0000-0003-0752-781X} } @article{MTMT:36226846, title = {Comparative Evaluation of Gelatin and HPMC Inhalation Capsule Shells Exposed to Simulated Humidity Conditions}, url = {https://m2.mtmt.hu/api/publication/36226846}, author = {MAGRAMANE, Sabrina and Kállai-Szabó, Nikolett and Farkas, Dóra and Süvegh, Károly and Zelkó, Romána and Antal, István}, doi = {10.3390/pharmaceutics17070877}, journal-iso = {PHARMACEUTICS}, journal = {PHARMACEUTICS}, volume = {17}, unique-id = {36226846}, abstract = {Background/Objectives: This study investigates the impact of high humidity (25 °C, 75% relative humidity) on gelatin and hydroxypropyl methylcellulose (HPMC) capsules used in dry powder inhalers (DPIs), focusing on moisture dynamics, structural responses, and mechanical performance, with an emphasis on understanding how different capsule types respond to prolonged exposure to humid conditions. Methods: Capsules were exposed to controlled humidity conditions, and moisture uptake was measured via thermal analysis. Visual observations of silica bead color changes were performed to assess moisture absorption, while surface wettability was measured using the sessile drop method. Hardness testing, mechanical deformation, and puncture tests were performed to evaluate structural and mechanical changes. Positron annihilation lifetime spectroscopy (PALS) was used to analyze free volume expansion. Results: HPMC capsules exhibited rapid moisture uptake, attributed to their lower equilibrium moisture content and ability to rearrange dynamically, preventing brittleness. In contrast, gelatin capsules showed slower moisture absorption but reached higher equilibrium levels, resulting in plasticization and softening. Mechanical testing showed that HPMC capsules retained structural integrity with minimal deformation, while gelatin capsules became softer and exhibited reduced puncture resistance. Structural analysis revealed greater free volume expansion in HPMC capsules, consistent with their amorphous nature, compared with gelatin’s semi-crystalline matrix. Conclusions: HPMC capsules demonstrated superior humidity resilience, making them more suitable for protecting moisture-sensitive active pharmaceutical ingredients (APIs) in DPI formulations. These findings underline the importance of appropriate storage conditions, as outlined in the Summary of Product Characteristics, to ensure optimal capsule performance throughout patient use.}, year = {2025}, eissn = {1999-4923}, orcid-numbers = {MAGRAMANE, Sabrina/0000-0001-6818-8300; Kállai-Szabó, Nikolett/0000-0002-8164-3993; Farkas, Dóra/0000-0003-4737-2108; Süvegh, Károly/0000-0001-8147-0546; Zelkó, Romána/0000-0002-5419-9137; Antal, István/0000-0002-5434-201X} } @article{MTMT:36241099, title = {How to manage the overwhelming amount of database-detected interactions? A focus group meeting study on the management of database-detected risks of drug interactions}, url = {https://m2.mtmt.hu/api/publication/36241099}, author = {Kleiner, Dénes and Haghverdi, Faraz and Szépe, Orsolya and Horváth, István László and Sebők, Szilvia and Csupor, Dezső and Horváth, András Attila and Balogh, Artúr György and Monostory, Katalin and Kóbori, László and Balázs, Máté Ádám and Dank, Magdolna and Móczár, Csaba and Becze, Ádám and Süle, András and Zelkó, Romána}, doi = {10.1136/ejhpharm-2025-004478}, journal-iso = {EUR J HOSP PHARM SCI PRACT}, journal = {EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE}, unique-id = {36241099}, issn = {2047-9956}, abstract = {Database-assisted screening may help detect the risks of drug interactions, but less than 10% of flagged interactions have clinical manifestations, potentially leading to alert fatigue among healthcare providers. To address this issue, this study aimed to develop a concise framework to support the management of database-indicated interaction risks.A grounded theory approach was used to design, evaluate and develop the framework. Participants included healthcare professionals and laypersons with experience using narrow therapeutic index medications, as well as individuals recommended by them. Two focus group discussions were conducted (N1=6 and N2=5), each lasting approximately 2 hours and following the same agenda. In one case, a follow-up one-on-one interview was held because the participant indicated further insights at the end of the session.Participants identified key decision-making questions for the framework, including the evidence base for interacting drugs, severity and documentation level of the interaction, availability of safer alternatives, and the presence of confounding factors. The framework was considered useful and, following refinement, potentially suitable for clinical implementation. A key insight was that integration into healthcare curricula is essential for achieving long-term impact. Overall, the proposed tool may assist in managing interaction risks in diverse clinical scenarios and reduce alert fatigue among healthcare professionals.Although further clinical validation is needed, the framework provides a foundation for improving the management of database-detected drug interactions.}, keywords = {clinical medicine; Evidence-Based Medicine; Education, Pharmacy; Drug-Related Side Effects and Adverse Reactions; Complementary therapies}, year = {2025}, eissn = {2047-9964}, orcid-numbers = {Kleiner, Dénes/0000-0002-4715-8695; Szépe, Orsolya/0009-0006-8174-4627; Csupor, Dezső/0000-0002-4088-3333; Kóbori, László/0000-0002-4843-6650; Balázs, Máté Ádám/0000-0002-1094-2523; Dank, Magdolna/0000-0002-4442-8733; Zelkó, Romána/0000-0002-5419-9137} } @article{MTMT:36245043, title = {Structure–dependent chlorine dioxide release from poly(acrylic acid) and hydroxyethyl cellulose hydrogels: Insights from real-time positron annihilation lifetime spectroscopy and quantum chemical calculations}, url = {https://m2.mtmt.hu/api/publication/36245043}, author = {Pegah, Poursafar and Nochta-Kazsoki, Adrienn Katalin and Palcsó, Barnabás and Károly, Süvegh and Zelkó, Romána}, doi = {10.1016/j.fochx.2025.102782}, journal-iso = {FOOD CHEM X}, journal = {FOOD CHEMISTRY: X}, volume = {29}, unique-id = {36245043}, issn = {2590-1575}, year = {2025}, eissn = {2590-1575}, orcid-numbers = {Nochta-Kazsoki, Adrienn Katalin/0000-0002-0611-3124; Palcsó, Barnabás/0000-0002-5593-1852; Zelkó, Romána/0000-0002-5419-9137} } @article{MTMT:34538437, title = {A Comparative Pharmacokinetic Study for Cysteamine-Containing Eye Drops as an Orphan Topical Therapy in Cystinosis}, url = {https://m2.mtmt.hu/api/publication/34538437}, author = {Csorba, Anita and Katona, Gábor and Budai-Szűcs, Mária and Balogh Weiser, Diána and Molnár, P. and Maka, Erika and Nochta-Kazsoki, Adrienn Katalin and Vajna, Márton Antal and Zelkó, Romána and Nagy, Zoltán Zsolt and Balogh, György Tibor}, doi = {10.3390/ijms25031623}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {25}, unique-id = {34538437}, issn = {1661-6596}, year = {2024}, eissn = {1422-0067}, orcid-numbers = {Csorba, Anita/0000-0002-3256-9440; Katona, Gábor/0000-0003-1564-4813; Budai-Szűcs, Mária/0000-0001-5187-5702; Balogh Weiser, Diána/0000-0002-9957-1203; Maka, Erika/0000-0002-3631-3506; Nochta-Kazsoki, Adrienn Katalin/0000-0002-0611-3124; Vajna, Márton Antal/0000-0001-5280-7533; Zelkó, Romána/0000-0002-5419-9137; Nagy, Zoltán Zsolt/0000-0002-7330-0464; Balogh, György Tibor/0000-0003-3347-1880} }