TY  - JOUR
AU  - Őrfi, Zoltán
AU  - Meggyesi, Nóra
AU  - Varga, Lívia
AU  - Bors, András
AU  - Gopcsa, László
AU  - Paksi, Melinda
AU  - Lakatos, Viktor
AU  - Kállay, Krisztián Miklós
AU  - Kriván, Gergely
AU  - Jónás, Alexa
AU  - Tordai, Attila
AU  - Vályi-Nagy, István
AU  - Reményi, Péter
AU  - Andrikovics, Hajnalka
TI  - Microchimaerismus kimutatása nagy érzékenységű droplet digitális PCR technikával és szerepe a vérképzőőssejt-transzplantált betegek monitorozásában
JF  - ORVOSI HETILAP
J2  - ORV HETIL
VL  - 165
PY  - 2024
IS  - 8
SP  - 297
EP  - 308
PG  - 12
SN  - 0030-6002
DO  - 10.1556/650.2024.32995
UR  - https://m2.mtmt.hu/api/publication/34687517
ID  - 34687517
LA  - Hungarian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Naffa, R.
AU  - Hegedűs, L.
AU  - Hegedűs, Tamás
AU  - Tóth, Sarolta
AU  - Papp, B.
AU  - Tordai, Attila
AU  - Enyedi, Ágnes
TI  - Plasma membrane Ca2+ pump isoform 4 function in cell migration and cancer metastasis
JF  - JOURNAL OF PHYSIOLOGY-LONDON
J2  - J PHYSIOL-LONDON
PY  - 2024
SN  - 0022-3751
DO  - 10.1113/JP284179
UR  - https://m2.mtmt.hu/api/publication/33731782
ID  - 33731782
LA  - English
DB  - MTMT
ER  - 

TY  - CHAP
AU  - Andrikovics, Hajnalka
AU  - Csabán, Dóra
AU  - Tordai, Attila
AU  - Őrfi, Zoltán
ED  - Ongrádi, József
ED  - Tordai, Attila
TI  - Örökletes genetikai eltérések diagnosztikája az orvosi gyakorlatban
T2  - Orvosi biotechnológia
PB  - Semmelweis Kiadó
CY  - Budapest
SN  - 9789633315682
PY  - 2022
SP  - 99
UR  - https://m2.mtmt.hu/api/publication/34043436
ID  - 34043436
LA  - Hungarian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Tarcsai, Katalin Réka
AU  - Corolciuc, Oliga
AU  - Tordai, Attila
AU  - Ongrádi, József
TI  - SARS-CoV-2 infection in HIV-infected patients: potential role in the high mutational load of the Omicron variant emerging in South Africa
JF  - GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE)
J2  - GEROSCIENCE
VL  - 44
PY  - 2022
IS  - 5
SP  - 2337
EP  - 2345
PG  - 9
SN  - 2509-2715
DO  - 10.1007/s11357-022-00603-6
UR  - https://m2.mtmt.hu/api/publication/33261135
ID  - 33261135
AB  - A new variant of SARS-CoV-2 named Omicron (B.1.1.529) was isolated from an HIV-infected patient in Botswana, South Africa, in November 2021. Whole genome sequencing revealed a multitude of mutations and its relationship to the mutation-rich Alpha variant that had been isolated from a cancer patient. It is conceivable that very high prevalence of HIV-infected individuals as susceptible hosts in South Africa and their immunocompromised state may predispose for accumulation of coronavirus mutations. Coronaviruses uniquely code for an N-terminal 3′ to 5′exonuclease (ExoN, nsp14) that removes mismatched nucleotides paired by the RNA dependent RNA polymerase. Its activity depends preferably on Mg2+ and other divalent cations (manganese, cobalt and zinc). On the contrary, methyl transferase activity of non-structural protein (nsp) 14 and nsp16 both complexed with nsp10 requires Mn2+. Enzymes in successive stages of HIV infections require the same cations. In HIV-infected organisms, a subsequent coronavirus infection encounters with altered homeostasis of the body including relative starvation of divalent cations induced by interleukin production of HIV-infected cells. It is hypothesized that selective diminished efficacy of ExoN in the absence of sufficient amount of magnesium may result in the accumulation of mutations. Unusual mutations and recombinations of heterologous viruses detected in AIDS patients also suggest that long-lasting persistence of superinfecting viruses may also contribute to the selection of genetic variants. Non-nucleoside reverse transcriptase inhibitors partially restore divalent cations’ equilibrium. As a practical approach, implementation of highly active antiretroviral therapy against HIV replication and vaccination against coronaviruses may be a successful strategy to reduce the risk of selection of similar mutants.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Mezei, Tünde
AU  - Bőde, Imre
AU  - Tenke, Péter
AU  - Jósa, Valéria
AU  - Merkel, Keresztély
AU  - Szilasi, Zsuzsanna
AU  - Tordai, Attila
AU  - Máthé, Domokos
AU  - Baranyai, Zsolt
TI  - The Correlation Between Platelet Count and Survival in Prostate Cancer
JF  - RESEARCH AND REPORTS IN UROLOGY
J2  - RESEARCH AND REPORTS IN UROLOGY
VL  - 14
PY  - 2022
SP  - 193
EP  - 202
PG  - 10
SN  - 2253-2447
DO  - 10.2147/RRU.S359715
UR  - https://m2.mtmt.hu/api/publication/32837228
ID  - 32837228
AB  - A number of studies have confirmed that elevated platelet count accompanying various solid tumours is associated with worse survival. However, only meagre data are available on the relationship between thrombocytosis and survival in prostate cancer.We conducted a retrospective analysis on clinical-pathological data accumulated from 316 patients during on average 51 months of follow-up after laparoscopic prostatectomy performed for prostate cancer. We analyzed the relationship between platelet count, risk factors, prostate-specific antigen (PSA) and cancer stage with use the Tumor, Node, Metastase system (TNM), as well as surgical margin, and prognosis.Thrombocytosis occurred in only one out of the 316 patients. The multivariate Cox proportional hazard model showed that preoperative PSA, risk group, preoperative haemoglobin level, and surgical margin status were significant, independent predictors of biochemical progression-free survival. By contrast, age at diagnosis and thrombocytosis had no such predictive value.We could not demonstrate an association between elevated platelet count and worse survival in our study population of patients with prostate cancer.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Fodor, Eszter
AU  - Müller, Veronika
AU  - Iványi, Zsolt
AU  - Berki, Tímea
AU  - Kuten Pella, Olga
AU  - Hornyák, István
AU  - Ambrus, Mira
AU  - Sárkány, Ágnes
AU  - Skázel, Árpád
AU  - Madár, Ágnes
AU  - Kardos, Dorottya
AU  - Kemenesi, Gábor
AU  - Földes, Fanni Vivien
AU  - Nagy, Sándor
AU  - Matusovits, Andrea
AU  - Nacsa, Janos
AU  - Tordai, Attila
AU  - Jakab, Ferenc
AU  - Lacza, Zsombor
TI  - Correction to : Early Transfusion of Convalescent Plasma Improves the Clinical Outcome in Severe SARS-CoV2 Infection.
JF  - INFECTIOUS DISEASES AND THERAPY
J2  - INFECT DIS THER
VL  - 11
PY  - 2022
IS  - 4
SP  - 1767
EP  - 1768
PG  - 2
SN  - 2193-8229
DO  - 10.1007/s40121-022-00637-5
UR  - https://m2.mtmt.hu/api/publication/32827541
ID  - 32827541
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Csanádi, Marcell
AU  - Ágh, Tamás
AU  - Tordai, Attila
AU  - Tapprich, Christoph
AU  - Vokó, Zoltán
AU  - Stamatopoulos, Kostas
TI  - Secondary primary malignancies after treatment with chemo-immunotherapy in treatment-naïve patients with CLL: a systematic literature review
JF  - EXPERT REVIEW OF HEMATOLOGY
J2  - EXPERT REV HEMATOL
VL  - 15
PY  - 2022
IS  - 3
SP  - 273
EP  - 284
PG  - 12
SN  - 1747-4086
DO  - 10.1080/17474086.2022.2042246
UR  - https://m2.mtmt.hu/api/publication/32691840
ID  - 32691840
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Oshakbayev, K.
AU  - Zhankalova, Z.
AU  - Gazaliyeva, M.
AU  - Mustafin, K.
AU  - Bedelbayeva, G.
AU  - Dukenbayeva, B.
AU  - Otarbayev, N.
AU  - Tordai, Attila
TI  - Association between COVID-19 morbidity, mortality, and gross domestic product, overweight/ obesity, non-communicable diseases, vaccination rate: A cross-sectional study
JF  - JOURNAL OF INFECTION AND PUBLIC HEALTH
J2  - J INFECT PUBLIC HEALTH
VL  - 15
PY  - 2022
IS  - 2
SP  - 255
EP  - 260
PG  - 6
SN  - 1876-0341
DO  - 10.1016/j.jiph.2022.01.009
UR  - https://m2.mtmt.hu/api/publication/32637858
ID  - 32637858
N1  - Export Date: 1 February 2022            
            Correspondence Address: Oshakbayev, K.Str. Kerey and Zhanibek Khans, 22, Kazakhstan; email: okp.kuat@gmail.com
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Fodor, Eszter
AU  - Müller, Veronika
AU  - Iványi, Zsolt
AU  - Berki, Tímea
AU  - Kuten Pella, Olga
AU  - Hornyák, István
AU  - Ambrus, Mira
AU  - Sárkány, Ágnes
AU  - Skázel, Árpád
AU  - Madár, Ágnes
AU  - Kardos, Dorottya Virág
AU  - Kemenesi, Gábor
AU  - Földes, Fanni Vivien
AU  - Nagy, Sándor
AU  - Matusovits, Andrea
AU  - Nacsa, János
AU  - Tordai, Attila
AU  - Jakab, Ferenc
AU  - Lacza, Zsombor
TI  - Early Transfusion of Convalescent Plasma Improves the Clinical Outcome in Severe SARS-CoV2 Infection
JF  - INFECTIOUS DISEASES AND THERAPY
J2  - INFECT DIS THER
VL  - 11
PY  - 2022
IS  - 1
SP  - 293
EP  - 304
PG  - 12
SN  - 2193-8229
DO  - 10.1007/s40121-021-00514-7
UR  - https://m2.mtmt.hu/api/publication/32507740
ID  - 32507740
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Erdélyi, Dániel
AU  - Kovács, Gábor
AU  - Szabó, Sándor
AU  - Szegedi, Zsolt
AU  - Tordai, Attila
TI  - Aktualitások az irradiált vérkészítmények indikációjában
JF  - HEMATOLÓGIA-TRANSZFUZIOLÓGIA
J2  - HEMATOLÓGIA-TRANSZFUZIOLÓGIA
VL  - 54
PY  - 2021
IS  - 4
SP  - 198
EP  - 204
PG  - 7
SN  - 1786-5913
DO  - 10.1556/2068.2021.54.4.6
UR  - https://m2.mtmt.hu/api/publication/32639206
ID  - 32639206
LA  - Hungarian
DB  - MTMT
ER  -