TY - JOUR AU - Ujma, Przemyslaw Péter AU - Bódizs, Róbert TI - Sleep alterations as a function of 88 health indicators JF - BMC MEDICINE J2 - BMC MED VL - 22 PY - 2024 IS - 1 PG - 15 SN - 1741-7015 DO - 10.1186/s12916-024-03358-3 UR - https://m2.mtmt.hu/api/publication/34765182 ID - 34765182 LA - English DB - MTMT ER - TY - JOUR AU - Bódizs, Róbert AU - Schneider, Bence AU - Ujma, Przemyslaw Péter AU - G. Horváth, Csenge AU - Dresler, Martin AU - Rosenblum, Yevgenia TI - Fundamentals of sleep regulation: Model and benchmark values for fractal and oscillatory neurodynamics JF - PROGRESS IN NEUROBIOLOGY: AN INTERNATIONAL REVIEW JOURNAL J2 - PROG NEUROBIOL VL - 234 PY - 2024 PG - 27 SN - 0301-0082 DO - 10.1016/j.pneurobio.2024.102589 UR - https://m2.mtmt.hu/api/publication/34736261 ID - 34736261 LA - English DB - MTMT ER - TY - JOUR AU - Vojnits, Blanka AU - Magyar, T.Z. AU - Szalárdy, Orsolya AU - Reicher, V. AU - Takács, M. AU - Bunford, N. AU - Bódizs, Róbert TI - Mobile sleep EEG suggests delayed brain maturation in adolescents with ADHD: A focus on oscillatory spindle frequency JF - RESEARCH IN DEVELOPMENTAL DISABILITIES J2 - RES DEV DISABIL VL - 146 PY - 2024 PG - 9 SN - 0891-4222 DO - 10.1016/j.ridd.2024.104693 UR - https://m2.mtmt.hu/api/publication/34720194 ID - 34720194 LA - English DB - MTMT ER - TY - JOUR AU - Szalárdy, Orsolya AU - Simor, Péter Dániel AU - Ujma, Przemyslaw Péter AU - Jordán, Zsófia AU - Halász, László AU - Erőss, Loránd AU - Fabó, Dániel AU - Bódizs, Róbert TI - Temporal association between sleep spindles and ripples in the human anterior and mediodorsal thalamus JF - EUROPEAN JOURNAL OF NEUROSCIENCE J2 - EUR J NEUROSCI VL - 59 PY - 2024 IS - 4 SP - 641 EP - 661 PG - 21 SN - 0953-816X DO - 10.1111/ejn.16240 UR - https://m2.mtmt.hu/api/publication/34505166 ID - 34505166 AB - Sleep spindles are major oscillatory components of Non-Rapid Eye Movement (NREM) sleep, reflecting hyperpolarization-rebound sequences of thalamocortical neurons. Reports suggest a link between sleep spindles and several forms of high-frequency oscillations which are considered as expressions of pathological off-line neural plasticity in the central nervous system. Here we investigated the relationship between thalamic sleep spindles and ripples in the anterior and mediodorsal nuclei (ANT and MD) of epilepsy patients. Whole-night LFP from the ANT and MD were co-registered with scalp EEG/polysomnography by using externalized leads in 15 epilepsy patients undergoing a Deep Brain Stimulation protocol. Slow (~12 Hz) and fast (~14 Hz) sleep spindles were present in the human ANT and MD and roughly, 20% of them were associated with ripples. Ripple-associated thalamic sleep spindles were characterized by longer duration and exceeded pure spindles in terms of spindle power as indicated by time-frequency analysis. Furthermore, ripple amplitude was modulated by the phase of sleep spindles within both thalamic nuclei. No signs of pathological processes were correlated with measures of ripple and spindle association, furthermore, the density of ripple-associated sleep spindles in the ANT showed a positive correlation with verbal comprehension. Our findings indicate the involvement of the human thalamus in coalescent spindle-ripple oscillations of NREM sleep. LA - English DB - MTMT ER - TY - JOUR AU - Ungvári, Zoltán István AU - Tabák, Ádám AU - Ádány, Róza AU - Purebl, György AU - Kaposvári, Csilla AU - Fazekas-Pongor, Vince AU - Csípő, Tamás AU - Szarvas, Zsófia AU - Horváth, Krisztián AU - Mukli, Péter AU - Balog, Piroska AU - Bódizs, Róbert AU - Ujma, Przemyslaw Péter AU - Stauder, Adrienne AU - Belsky, Daniel W. AU - Kovács, Illés AU - Yabluchanskiy, Andriy AU - Maier, Andrea B. AU - Moizs, Mariann AU - Östlin, Piroska AU - Yon, Yongjie AU - Varga, Péter AU - Vokó, Zoltán AU - Papp, Magor Csongor AU - Takács, István AU - Vásárhelyi, Barna AU - Torzsa, Péter AU - Ferdinandy, Péter AU - Csiszar, Anna AU - Benyó, Zoltán AU - Szabó, Attila AU - Bednárikné Dörnyei, Gabriella AU - Kivimäki, Mika AU - Kellermayer, Miklós AU - Merkely, Béla Péter TI - The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging JF - GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE) J2 - GEROSCIENCE VL - 46 PY - 2024 IS - 1 SP - 191 EP - 218 PG - 28 SN - 2509-2715 DO - 10.1007/s11357-023-01018-7 UR - https://m2.mtmt.hu/api/publication/34425939 ID - 34425939 N1 - International Training Program in Geroscience/Healthy Aging Program, Doctoral School of Basic and Translational Medicine/Department of Public Health, Semmelweis University, Budapest, Hungary Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States Department of Health Promotion Sciences, The Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States Department of Public Health, Faculty of Medicine, Semmelweis University, Budapest, Hungary UCL Brain Sciences, University College London, London, United Kingdom Department of Internal Medicine and Oncology, Semmelweis University, Faculty of Medicine, Budapest, Hungary HUN-REN-UD Public Health Research Group, Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary Institute of Behavioral Sciences, Faculty of Medicine, Semmelweis University, Budapest, Hungary Robert N. Butler Columbia Aging Center, Columbia University, New York, NY, United States Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, United States Department of Ophthalmology, Faculty of Medicine, Semmelweis University, Budapest, Hungary Department of Ophthalmology, Weill Cornell Medical College, New York City, NY, United States Department of Clinical Ophthalmology, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Centre for Healthy Longevity, National University Health System, Singapore, Singapore Department of Human Movement Sciences, @AgeAmsterdam, Vrije Universiteit, Amsterdam Movement Sciences, Amsterdam, Netherlands Ministry of Interior of Hungary, Budapest, Hungary WHO Regional Office for Europe, Copenhagen, Denmark Clinical Center, Semmelweis University, Budapest, Hungary Center for Health Technology Assessment, Semmelweis University, Budapest, Hungary Department of Laboratory Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary Department of Family Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Budapest, Hungary Department of Translational Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary HUN-REN-SU Cerebrovascular and Neurocognitive Diseases Research Group, Budapest, Hungary First Department of Pediatrics, Faculty of Medicine, Semmelweis University, Budapest, Hungary HUN-REN-SU Pediatrics and Nephrology Research Group, Semmelweis University, Budapest, Hungary Department of Morphology and Physiology, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary Department of Biophysics and Radiation Biology, Faculty of Medicine, Semmelweis University, Budapest, Hungary Heart and Vascular Center, Semmelweis University, Budapest, Hungary Cited By :1 Export Date: 29 February 2024 Correspondence Address: Ungvari, Z.; International Training Program in Geroscience/Healthy Aging Program, Hungary; email: Zoltan-Ungvari@ouhsc.edu Correspondence Address: Adany, R.; International Training Program in Geroscience/Healthy Aging Program, Hungary AB - The Semmelweis Study is a prospective occupational cohort study that seeks to enroll all employees of Semmelweis University (Budapest, Hungary) aged 25 years and older, with a population of 8866 people, 70.5% of whom are women. The study builds on the successful experiences of the Whitehall II study and aims to investigate the complex relationships between lifestyle, environmental, and occupational risk factors, and the development and progression of chronic age-associated diseases. An important goal of the Semmelweis Study is to identify groups of people who are aging unsuccessfully and therefore have an increased risk of developing age-associated diseases. To achieve this, the study takes a multidisciplinary approach, collecting economic, social, psychological, cognitive, health, and biological data. The Semmelweis Study comprises a baseline data collection with open healthcare data linkage, followed by repeated data collection waves every 5 years. Data are collected through computer-assisted self-completed questionnaires, followed by a physical health examination, physiological measurements, and the assessment of biomarkers. This article provides a comprehensive overview of the Semmelweis Study, including its origin, context, objectives, design, relevance, and expected contributions. LA - English DB - MTMT ER - TY - JOUR AU - G. Horváth, Csenge AU - Bódizs, Róbert TI - Association of actigraphy-derived circadian phase indicators with the nadir of spindle frequency JF - BIOLOGICAL RHYTHM RESEARCH J2 - BIOL RHYTHM RES VL - 55 PY - 2024 IS - 1 SP - 16 EP - 29 PG - 14 SN - 0929-1016 DO - 10.1080/09291016.2023.2283656 UR - https://m2.mtmt.hu/api/publication/34351290 ID - 34351290 N1 - Export Date: 13 February 2024 CODEN: BRHRE Correspondence Address: G. Horváth, C.; Institute of Behavioural Sciences, Nagyvárad tér 4, Hungary; email: horvath.csenge@phd.semmelweis.hu LA - English DB - MTMT ER - TY - CHAP AU - Maczák, Bálint AU - G. Horváth, Csenge AU - Bódizs, Róbert AU - Vadai, Gergely ED - Theodorou, Christoforos TI - Revealing the generality of 1/f noise based spectral characteristics of human activity across different datasets T2 - Proceedings of the 26th International Conference on Noise and Fluctuations PB - IEEE CY - Grenoble PY - 2023 PG - 4 DO - 10.1109/ICNF57520.2023.10472765 UR - https://m2.mtmt.hu/api/publication/34721242 ID - 34721242 LA - English DB - MTMT ER - TY - JOUR AU - Vojnits, Blanka AU - Bódizs, Róbert TI - A pszichostimulánsok alkalmazásának alvásra gyakorolt hatása figyelemhiányos hiperaktivitás zavarral élő gyerekek körében: a poliszomnográfiás vizsgálatok szakirodalmának szisztematikus áttekintése JF - NEUROPSYCHOPHARMACOLOGIA HUNGARICA J2 - NEUROPSYCHOPHARM HUNG VL - 25 PY - 2023 IS - 4 SP - 212 EP - 222 PG - 11 SN - 1419-8711 UR - https://m2.mtmt.hu/api/publication/34499320 ID - 34499320 N1 - Export Date: 17 January 2024; Cited By: 0 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Ujma, Przemyslaw Péter AU - Bódizs, Róbert AU - Dresler, Martin AU - Simor, Péter Dániel AU - Purcell, Shaun AU - Stone, Katie L. AU - Yaffe, Kristine AU - Redline, Susan TI - Multivariate prediction of cognitive performance from the sleep electroencephalogram JF - NEUROIMAGE J2 - NEUROIMAGE VL - 279 PY - 2023 PG - 13 SN - 1053-8119 DO - 10.1016/j.neuroimage.2023.120319 UR - https://m2.mtmt.hu/api/publication/34104613 ID - 34104613 N1 - Semmelweis University, Institute of Behavioural Sciences, Budapest, Hungary Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center Nijmegen, Nijmegen, Netherlands Institute of Psychology, Eötvös Loránd University, Budapest, Hungary Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Harvard University, United States California Pacific Medical Center Research Institute, San Francisco, CA, United States Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, United States Department of Psychiatry, University of California, San Francisco, CA, United States Department of Neurology, University of California, San Francisco, CA, United States San Francisco VA Medical Center, San Francisco, CA, United States Brigham and Women's Hospital, Harvard University, Boston, MA, United States Export Date: 13 February 2024 CODEN: NEIME Correspondence Address: Ujma, P.P.; Semmelweis University, Hungary; email: ujma.peter@med.semmelweis-univ.hu LA - English DB - MTMT ER - TY - JOUR AU - Ujma, Przemyslaw Péter AU - G. Horváth, Csenge AU - Bódizs, Róbert TI - Daily rhythms, light exposure and social jetlag correlate with demographic characteristics and health in a nationally representative survey JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 13 PY - 2023 IS - 1 PG - 14 SN - 2045-2322 DO - 10.1038/s41598-023-39011-x UR - https://m2.mtmt.hu/api/publication/34081564 ID - 34081564 AB - The timing of daily activity in humans have been associated with various demographic and health-related factors, but the possibly complex patterns of confounding and interaction between these has not been systematically explored. We use data from Hungarostudy 2021, a nationally representative survey of 7000 Hungarian adults to assess the relationship between self-reported chronotype, social jetlag (using the Munich Chronotype Questionnaire), demographic variables and self-reported health and demographic variables, including ethnic minority membership. Supporting the validity of self-reports, participants with later chronotypes reported the lowest daytime sleepiness at a later clock time. We found that older age, female sex, a more eastward and southward geographical position, residence in a smaller settlement, less education and income, religiousness and cohabiting with small children were associated with an earlier chronotype. Younger age, higher education and income, and cohabiting with small children were associated with increased social jetlag. Of the 48 health-related variables surveyed, the relationship with both chronotype and social jetlag were mostly accounted for by age, sex, and socioeconomic effects, but we identified alcohol consumption, smoking, and physical activity as predictors of both social jetlag and chronotype, while a number of disorders were either positively or negatively associated with chronotype and social jetlag. Our findings from a large, nationally representative sample indicate that both biological and social factors influence chronotype and identified both demographic and health-related variables as risk factors for social jetlag. Our results, however, do not support a causal relationship between light exposure and mental health. LA - English DB - MTMT ER -