@article{MTMT:34763514,
title = {Clinical Benefits of Decreased Photo-Oxidative Stress on Human Embryo Development},
url = {https://m2.mtmt.hu/api/publication/34763514},
author = {Gödöny, Krisztina and Herczeg, Róbert and Gyenesei, Attila and Várnagy, Ákos and Bognár, Zoltán and Kovács, L. Gábor and Szekeres, Júlia and Mauchart, Péter and Nagy, Bernadett and Erostyák, János and Kovács, Kálmán András and Bódis, József},
doi = {10.1159/000536358},
journal-iso = {MED PRIN PRACT},
journal = {MEDICAL PRINCIPLES AND PRACTICE},
unique-id = {34763514},
issn = {1011-7571},
abstract = {Objective: Early embryonic development is characterized by rapid cell division and gene activation, making the embryo extremely sensitive to environmental influences. Light exposure can affect embryonic development through a direct toxic effect on the embryo via the generation of reactive oxygen species. In a previous study, we demonstrated the positive effect of improved light-protected embryo culture conditions implemented in our laboratory. This study aimed to investigate the changes in human embryo development under light protection during the conventional in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). Materials and Methods: We tested the potential beneficial effect of light filters to reduce the risk of toxic effects of light. IVF outcomes were compared between two experimental conditions, light protection with red light filters versus no light protection as a control. Results: Blastocyst development rate in IVF was significantly higher in the light-protected group than in the group treated under conventional conditions (46.6 vs. 26.7%). In the case of ICSI, we obtained a similar result (44.5 vs. 31.6%). The rate of cryopreservation with at least one embryo was higher in the light-protected phase (32.8%) than in the conventionally manipulated phase (26.8%). The abortion rate was also significantly lower during the light-protected period in IVF, resulting in a higher live birth rate. Conclusions: The implementation of light protection to reduce the embryotoxic wavelengths of light in IVF centers may improve the blastocyst development rate and embryo quality while maintaining embryo safety.},
keywords = {blastocyst; abortion; intracytoplasmic sperm injection; In vitro fertilization; Live birth rate; light protection},
year = {2024},
eissn = {1423-0151},
orcid-numbers = {Herczeg, Róbert/0000-0002-5903-0082; Kovács, L. Gábor/0000-0001-5298-5401}
}
@CONFERENCE{MTMT:34667323,
title = {Magyarországi területi egyenlőtlenségek elemzése a női infertilitás diagnózis esetében},
url = {https://m2.mtmt.hu/api/publication/34667323},
author = {Pónusz-Kovács, Dalma and Csákvári, Tímea and Kajos, Luca Fanni and Elmer, Diána and Pónusz, Róbert and Bódis, József and Boncz, Imre},
booktitle = {Jubileumi Szakkollégiumi Konferencia: Absztrakt kötet},
unique-id = {34667323},
year = {2024},
pages = {20-20},
orcid-numbers = {Csákvári, Tímea/0000-0002-3339-4953; Kajos, Luca Fanni/0000-0002-0574-5787; Boncz, Imre/0000-0003-3699-6236}
}
@misc{MTMT:34525481,
title = {Detection of Ultraweak Photon Emissions from Mouse Embryos with Implications for Assisted Reproduction},
url = {https://m2.mtmt.hu/api/publication/34525481},
author = {Bódis, József and Bognár, Zoltán and Csabai-Tanics, Tímea Judith and Berke, József and Gulyás, István Tibor and Mauchart, Péter and Hans-Rudolf, Tinneberg and Farkas, Bálint and Várnagy, Ákos and Kovács, Kálmán András},
unique-id = {34525481},
year = {2024},
orcid-numbers = {Berke, József/0000-0002-0190-4197; Farkas, Bálint/0000-0003-0638-2057}
}
@misc{MTMT:34525317,
title = {Unique algorithm for the evaluation of embryo photon emission and viability},
url = {https://m2.mtmt.hu/api/publication/34525317},
author = {Berke, József and Gulyás, István Tibor and Bognár, Zoltán and Dávid, Berke and Attila, Enyedi and Veronika, Kozma-Bognár and Mauchart, Péter and Nagy, Bernadett and Várnagy, Ákos and Kovács, Kálmán András and Bódis, József},
unique-id = {34525317},
year = {2024},
orcid-numbers = {Berke, József/0000-0002-0190-4197}
}
@misc{MTMT:34525263,
title = {Epidemiological disease burden and annual, nationwide health insurance treatment cost of female infertility based on real-world health insurance claims data in Hungary},
url = {https://m2.mtmt.hu/api/publication/34525263},
author = {Pónusz-Kovács, Dalma and Csákvári, Tímea and Kajos, Luca Fanni and Elmer, Diána and Pónusz, Róbert and Kovács, Bettina and Várnagy, Ákos and Kovács, Kálmán András and Bódis, József and Boncz, Imre},
unique-id = {34525263},
year = {2024},
orcid-numbers = {Csákvári, Tímea/0000-0002-3339-4953; Kajos, Luca Fanni/0000-0002-0574-5787; Boncz, Imre/0000-0003-3699-6236}
}
@misc{MTMT:34506735,
title = {A női infertilitással összefüggő egészségbiztosítási kiadások elemzése Magyarországon a 2010-2019. közötti időszakban című poszter bemutatása},
url = {https://m2.mtmt.hu/api/publication/34506735},
author = {Pónusz-Kovács, Dalma and Pónusz, Róbert and Kajos, Luca Fanni and Csákvári, Tímea and Bódis, József and Boncz, Imre},
unique-id = {34506735},
year = {2023},
orcid-numbers = {Kajos, Luca Fanni/0000-0002-0574-5787; Csákvári, Tímea/0000-0002-3339-4953; Boncz, Imre/0000-0003-3699-6236}
}
@article{MTMT:34477408,
title = {Thrombocytes and Platelet-Rich Plasma as Modulators of Reproduction and Fertility},
url = {https://m2.mtmt.hu/api/publication/34477408},
author = {Nagy, Bernadett and Kovács, Kálmán András and Sulyok, Endre and Várnagy, Ákos and Bódis, József},
doi = {10.3390/ijms242417336},
journal-iso = {INT J MOL SCI},
journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
volume = {24},
unique-id = {34477408},
issn = {1661-6596},
abstract = {Thrombocytes play an essential role in hemostasis and thrombosis. Moreover, the controlled activation of thrombocytes is required in reproduction and fertility. The platelet-activating factor and the controlled activation of platelets have important roles in folliculogenesis, ovulation, placental development, implantation and embryo development. Activated platelets accumulate in the follicular vessels surrounding the follicle and, due to its released soluble molecules (factors, mediators, chemokines, cytokines, neurotransmitters), locally increase oocyte maturation and hormone secretion. Furthermore, activated platelets are involved in the pathogenesis of ovarian hyperstimulation syndrome (OHSS) and preeclampsia. Low-dose aspirin can prevent OHSS during ovulation induction, while intrauterine or intraovarian administration of platelet-rich plasma (PRP) increases the endometrium thickness and receptivity as well as oocyte maturation. Activated thrombocytes rapidly release the contents of intracellular granules and have multiple adhesion molecules and receptors on their surface. Considering the numerous homeostatic endocrine functions of thrombocytes, it is reasonable to suppose a platelet-associated regulatory system (PARS) in reproduction. Although we are far from a complete understanding of the regulatory processes, the results of PARS research and the therapeutic application of aspirin and PRP during in vitro fertilization are promising.},
keywords = {reproduction; ASPIRIN; fertility; PREECLAMPSIA; In vitro fertilization; Thrombocytes; platelet-reach plasma},
year = {2023},
eissn = {1422-0067}
}
@article{MTMT:34227655,
title = {The Effect of Holder Pasteurization and Different Variants on Breast Milk Antioxidants},
url = {https://m2.mtmt.hu/api/publication/34227655},
author = {Vass, Réka Anna and Mikó, Éva and Gál, Csenge and Kőszegi, Tamás and Vass, Csaba I and Bokor, Szilvia and Molnár, Dénes and Funke Kiss, Simone and Kovács, Kálmán András and Bódis, József and Ertl, Tibor},
doi = {10.3390/antiox12101857},
journal-iso = {ANTIOXIDANTS-BASEL},
journal = {ANTIOXIDANTS},
volume = {12},
unique-id = {34227655},
abstract = {After birth, breast milk (BM) is a known essential source of antioxidants for infants. We analyzed the non-enzymatic total antioxidant capacity (TAC), oxygen radical absorbance capacity (ORAC), and glutathione, calcium, transferrin, and total protein levels of human breast milk before and after Holder pasteurization (HoP).The collected donor BM samples were pasteurized with HoP.HoP decreased TAC (-12.6%), ORAC (-12.1%), transferrin (-98.3%), and total protein (-21.4%) levels; HoP did not influence the glutathione concentration, and it increased the total calcium (+25.5%) concentration. Mothers who gave birth via Cesarean section had significantly lower TAC in their BM. TAC and glutathione levels were elevated in the BM of mothers over the age of 30. BM produced in the summer had higher glutathione and calcium levels compared to BM produced in the winter. The glutathione concentration in term milk samples was significantly higher in the first two months of lactation compared to the period between the third and sixth months. The transferrin level of BM for female infants was significantly higher than the BM for boys, and mothers with a BMI above 30 had increased transferrin in their samples.Antioxidant levels in human milk are influenced by numerous factors. Environmental and maternal factors, the postpartum age at breast milk collection, and Holder pasteurization of the milk influence the antioxidant intake of the infant.},
keywords = {calcium; GLUTATHIONE; TRANSFERRIN; TAC; breast milk; Total protein; donor milk; ORAC},
year = {2023},
eissn = {2076-3921},
orcid-numbers = {Vass, Réka Anna/0000-0002-0436-4261; Molnár, Dénes/0000-0002-3675-7019}
}
@article{MTMT:34214974,
title = {The investigation of endometrial microbiota and its possible role in IVF success},
url = {https://m2.mtmt.hu/api/publication/34214974},
author = {Mikó, Éva and Császár, András and Kovacs, Kalman and Szekeres, Júlia and Bódis, József},
doi = {10.1016/j.jri.2023.104034},
journal-iso = {J REPROD IMMUNOL},
journal = {JOURNAL OF REPRODUCTIVE IMMUNOLOGY},
volume = {159},
unique-id = {34214974},
issn = {0165-0378},
keywords = {immunology},
year = {2023},
eissn = {1872-7603},
pages = {18-18}
}
@article{MTMT:34196772,
title = {Disrupted Balance of the Oxidant–Antioxidant System in the Pathophysiology of Female Reproduction: Oxidative Stress and Adverse Pregnancy Outcomes},
url = {https://m2.mtmt.hu/api/publication/34196772},
author = {Joó, József Gábor and Sulyok, Endre and Bódis, József and Kornya, László},
doi = {10.3390/cimb45100511},
journal-iso = {CURR ISSUES MOL BIOL},
journal = {CURRENT ISSUES IN MOLECULAR BIOLOGY},
volume = {45},
unique-id = {34196772},
issn = {1467-3037},
abstract = {The significance of oxidative stress in the pathophysiology of male reproductive processes has been closely studied in the last two decades. Recently, it has become clear that oxidative stress can lead to numerous pathological conditions during female reproductive processes as well, contributing to the development of endometriosis, polycystic ovary syndrome and various forms of infertility. During pregnancy, physiological generation of reactive oxygen species (ROS) occurs in association with several developmental processes including oocyte maturation and implantation. An overproduction of ROS can lead to disturbances in fetal development and increases the risk for missed abortion, intrauterine growth restriction, pre-eclampsia, premature delivery and gestational diabetes. Our review focuses on the etiological role of the disrupted oxidant–antioxidant system during human gestation as it relates to adverse pregnancy outcomes.},
year = {2023},
eissn = {1467-3045},
pages = {8091-8111},
orcid-numbers = {Joó, József Gábor/0000-0001-9820-6514}
}