TY - JOUR AU - Emmanuel, Michael AU - Horváth, Dezső AU - Tóth, Ágota AU - Abou-Hassan, Ali TI - Harnessing flow and microfluidics to direct inorganic crystal growth and architecture JF - CRYSTENGCOMM J2 - CRYSTENGCOMM VL - 28 PY - 2026 IS - 1 SP - 51 EP - 66 PG - 16 SN - 1466-8033 DO - 10.1039/D5CE00985E UR - https://m2.mtmt.hu/api/publication/36487209 ID - 36487209 AB - Flow-driven systems enable precise control of inorganic crystal nucleation, polymorph selection, and self-organization, creating tunable crystalline architectures under far-from-equilibrium conditions. LA - English DB - MTMT ER - TY - JOUR AU - Bortnikov, Evgeniy O AU - Paikar, Arpita AU - Zhigileva, Ekaterina A AU - Fomitskaya, Polina AU - Ariel, Noam AU - Diskin-Posner, Yael AU - Avram, Liat AU - Sui, Xiao-Meng AU - Skorb, Ekaterina V AU - Sütő, István AU - Horváth, Dezső AU - Tóth, Ágota AU - Semenov, Sergey N TI - Designing soft materials through synthetic morphogenesis JF - NATURE COMMUNICATIONS J2 - NAT COMMUN VL - 17 PY - 2026 IS - 1 PG - 11 SN - 2041-1723 DO - 10.1038/s41467-026-71999-4 UR - https://m2.mtmt.hu/api/publication/37108844 ID - 37108844 AB - While the principles of Turing-type morphogenesis are central to understanding biological pattern formation, their rational application for the design of synthetic materials remains a significant challenge. To address this gap, we rationally design stationary reaction-diffusion patterns using a chemical reaction network (CRN) of small organic molecules bearing thiol groups - a functional handle ubiquitous in materials chemistry. The CRN features autocatalysis coupled with both rapid direct inhibition and a negative feedback loop. We report the formation of dot, line, and net patterns obtained with the assistance of numerical modeling by adjusting reactant feed rates and concentrations. The use of disulfide-crosslinked polyacrylamide hydrogels enables the modulation of thiol diffusion and subsequent derivatization of the immobilized thiols with dyes, enzymes, and crosslinkers to produce soft materials. This entire process, from out-of-equilibrium self-organization to a patterned soft material, conceptually resembles the biological process that gives rise to skin patterns. Overall, this work establishes a pathway for applying Turing-type self-organization to the structuring of synthetic matter. © 2026. The Author(s). LA - English DB - MTMT ER - TY - JOUR AU - Zahorán, Réka AU - Papp, Paszkál AU - Horváth, Dezső AU - Tóth, Ágota TI - Collective dynamics and self-assembly of calcium-alginate motors of varying sizes JF - SCIENTIFIC REPORTS J2 - SCI REP PY - 2026 SN - 2045-2322 DO - 10.1038/s41598-026-61454-1 UR - https://m2.mtmt.hu/api/publication/37406019 ID - 37406019 AB - Self-propelling calcium-alginate motors exhibit complex interactions driven by attractive capillary and repulsive Marangoni forces, yet how motor size influences their collective dynamics remains unclear. Here we experimentally investigate the size-dependent oscillatory collisions, synchronization, and self-assembly of calcium-alginate motors ranging from two to fifteen units. Using high-speed imaging and a particle-based model incorporating pairwise interactions, we reveal that smaller motors sustain longer oscillations, while larger motors coordinate the motion of smaller ones, leading to vibrational-like dynamics. Assemblies of eight or more motors form clusters characterized topologically by Betti numbers, reflecting evolving connectivity and voids. Our findings elucidate how size-dependent forces govern the emergent spatiotemporal patterns and self-organization of active polymer motors, providing insights for designing intelligent collective systems with potential applications in micro-actuation and soft robotics. LA - English DB - MTMT ER - TY - JOUR AU - Maćešić, Stevan AU - Tóth, Ágota AU - Horváth, Dezső TI - Reaction–Diffusion and Diffusion-Driven Fronts in Reversible Redox Autocatalytic Networks JF - CHEMSYSTEMSCHEM J2 - CHEMSYSTEMSCHEM VL - 8 PY - 2026 IS - 5 PG - 9 SN - 2570-4206 DO - 10.1002/syst.70046 UR - https://m2.mtmt.hu/api/publication/37475267 ID - 37475267 N1 - EID: 2-s2.0-105047552393 Export Date: 09 October 2026 Cited By: 0 Correspondence Address: D. Horváth; Department of Applied and Environmental Chemistry, University of Szeged, Szeged, Hungary; email: horvathd@chem.u-szeged.hu AB - Autocatalysis plays a critical role in the self‐organization of chemical and biological systems, influencing phenomena such as bistability and reaction–diffusion front formation. In the rhizosphere, the regulation of reactive oxygen species (ROS) is mediated by intricate networks of reversible autocatalytic reactions, yet the mechanisms governing their spatiotemporal dynamics remain unclear. Here, we perform comprehensive numerical simulations of a reaction–diffusion model for ROS dynamics incorporating redox couples, sodium borohydride, and oxygen. We identify oxidation‐driven autocatalysis as the primary mechanism responsible for the emergence of stable reaction–diffusion fronts that propagate with constant velocity and shape, whereas reduction fronts display diffusive broadening attenuated by the local oxygen concentration. Furthermore, we demonstrate that reversible quadratic autocatalytic cycles coupled to a simple autocatalyst removal and diffusion are sufficient to reproduce these characteristic front behaviors. These results also provide insights that are transferable to a wide range of autocatalytic networks exhibiting spatiotemporal pattern formation. LA - English DB - MTMT ER - TY - JOUR AU - Paikar, A. AU - Li, X. AU - Avram, L. AU - Smith, B.S. AU - Sütő, István AU - Horváth, Dezső AU - Rennert, E. AU - Qiu, Y. AU - Tóth, Ágota AU - Vaikuntanathan, S. AU - Semenov, S.N. TI - Chemical waves in reaction-diffusion networks of small organic molecules JF - CHEMICAL SCIENCE J2 - CHEM SCI VL - 16 PY - 2025 IS - 2 SP - 659 EP - 669 PG - 11 SN - 2041-6520 DO - 10.1039/d4sc06351a UR - https://m2.mtmt.hu/api/publication/35708780 ID - 35708780 N1 - Department of Molecular Chemistry and Materials Science, Weizmann Institute of Science, Rehovot, Israel Department of Chemistry, Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Southern University of Science and Technology, Shenzhen, China Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States Department of Physical Chemistry and Materials Science, University of Szeged, Szeged, Hungary Department of Applied and Environmental Chemistry, University of Szeged, Szeged, Hungary Graduate Program in Biophysical Sciences, University of Chicago, Chicago, IL, United States Department of Chemistry, University of Chicago, Chicago, IL, United States Export Date: 22 January 2025 CODEN: CSHCC Correspondence Address: Semenov, S.N.; Department of Molecular Chemistry and Materials Science, Israel; email: sergey.semenov@weizmann.ac.il LA - English DB - MTMT ER - TY - JOUR AU - Papp, Paszkál AU - Pecze, L. AU - Lantos, Emese AU - Tóth, Petra AU - Tóth, Ágota AU - Horváth, Dezső TI - Convection-driven mixing inside microdroplets JF - INTERNATIONAL JOURNAL OF MULTIPHASE FLOW J2 - INT J MULTIPHAS FLOW VL - 191 PY - 2025 PG - 7 SN - 0301-9322 DO - 10.1016/j.ijmultiphaseflow.2025.105277 UR - https://m2.mtmt.hu/api/publication/36185718 ID - 36185718 N1 - Department of Physical Chemistry and Materials Science, University of Szeged, Rerrich Béla tér 1., Szeged, H-6720, Hungary Department of Applied and Environmental Chemistry, University of Szeged, Rerrich Béla tér 1., Szeged, H-6720, Hungary Export Date: 11 June 2025; Cited By: 0; Correspondence Address: D. Horváth; Department of Applied and Environmental Chemistry, University of Szeged, Szeged, Rerrich Béla tér 1., H-6720, Hungary; email: horvathd@chem.u-szeged.hu AB - Droplet generators represent a fast-growing area of microfluidics, since each volume of the dispersed phase functions as an individual microreactor, therefore they offer high throughput and reduced sample consumption. By injecting the dispersed phases containing the reactants, the mixing can be tuned separately, thus a higher control over reactions inside the droplets is achievable. The numerical investigation of such multi-phase and multi-component systems proposes various challenges, since the concentrations of species also depend on the distribution of phases. In this article, we investigate the concentration distribution of the species in microfluidic droplet generators both experimentally and theoretically. Besides the characterization of the distribution of the dispersed and continuous phases, we have also studied the effect of injection rates on mixing inside the droplets. The size of the droplets decreases on increasing the flow rate of the oil phase and increases on increasing the flow rate of water phase compared to the oil phase. The numerical analysis based on solving the Navier–Stokes equation with volume-of-fluid method including a diffusive component in the aqueous phase corroborated the experimental findings. Furthermore, by determining the contribution of various transport processes to mixing of reactants inside the dispersed phases, we have shown that convection is dominant inside the droplets for all parameters used. © 2025 The Authors LA - English DB - MTMT ER - TY - JOUR AU - Gárdi, Bálint AU - Kumar, Pawan AU - Horváth, Dezső AU - Tóth, Ágota TI - Synchronization modes of chitosan surfers with various sizes JF - SOFT MATTER J2 - SOFT MATTER VL - 21 PY - 2025 IS - 46 SP - 8803 EP - 8810 PG - 8 SN - 1744-683X DO - 10.1039/D5SM00857C UR - https://m2.mtmt.hu/api/publication/36413960 ID - 36413960 AB - The interplay of capillary attraction and Marangoni-driven repulsion between two surfer beads results in a spatial oscillator. In clusters of these beads the coupling leads to partially and fully synchronized states depending on their size. LA - English DB - MTMT ER - TY - JOUR AU - Papp, Paszkál AU - Tóth, Ágota AU - Horváth, Dezső TI - Population Mass Balance Model for Precipitation with Turbidity Measurements JF - ACS OMEGA J2 - ACS OMEGA VL - 9 PY - 2024 IS - 11 SP - 13412 EP - 13417 PG - 6 SN - 2470-1343 DO - 10.1021/acsomega.3c10516 UR - https://m2.mtmt.hu/api/publication/34728312 ID - 34728312 LA - English DB - MTMT ER - TY - JOUR AU - Stergiou, Yorgos AU - Escala, Dario M. AU - Papp, Paszkál AU - Horváth, Dezső AU - Hauser, Marcus J. B. AU - Brau, Fabian AU - De Wit, Anne AU - Tóth, Ágota AU - Eckert, Kerstin AU - Schwarzenberger, Karin TI - Unraveling dispersion and buoyancy dynamics around radial A + B → C reaction fronts: microgravity experiments and numerical simulations JF - NPJ MICROGRAVITY J2 - NPJ MICROGRAVITY VL - 10 PY - 2024 IS - 1 PG - 9 SN - 2373-8065 DO - 10.1038/s41526-024-00390-8 UR - https://m2.mtmt.hu/api/publication/34902412 ID - 34902412 LA - English DB - MTMT ER - TY - JOUR AU - Papp, Paszkál AU - Tóth, Ágota AU - Horváth, Dezső TI - PaReDiSo: A reaction-diffusion solver coupled with OpenMPI and CVODE JF - COMPUTER PHYSICS COMMUNICATIONS J2 - COMPUT PHYS COMMUN VL - 301 PY - 2024 PG - 7 SN - 0010-4655 DO - 10.1016/j.cpc.2024.109193 UR - https://m2.mtmt.hu/api/publication/34983416 ID - 34983416 LA - English DB - MTMT ER -