TY - GEN AU - Nagy, András Péter AU - Bak, Mihály AU - Kenessey, István TI - A Colorectalis betegségek prevenciója elektromágneses rezonancia segítségével PY - 2021 UR - https://m2.mtmt.hu/api/publication/32548304 ID - 32548304 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Nagy, András Péter AU - Kenessey, István AU - Bak, Mihály TI - Colorectalis betegségek diagnosztizálása MORA készülékkel (prospektív tanulmány) JF - FOCUS MEDICINAE J2 - FOCUS MEDICINAE VL - 21 PY - 2019 IS - 4 SP - 35 EP - 40 PG - 6 SN - 1419-0478 UR - https://m2.mtmt.hu/api/publication/31400437 ID - 31400437 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Nagy, András Péter AU - Kenessey, István AU - Bak, Mihály TI - Colorectalis betegségek diagnosztizálása MORA készülékkel JF - MAGYAR SEBÉSZET J2 - MAGYAR SEBÉSZET VL - 72 PY - 2019 IS - 3 SP - 137 EP - 137 PG - 1 SN - 0025-0295 UR - https://m2.mtmt.hu/api/publication/31400427 ID - 31400427 LA - Hungarian DB - MTMT ER - TY - CHAP AU - Cserni, Gábor AU - Mátrai, Zoltán Tamás AU - Bak, Mihály ED - Mátrai, Zoltán Tamás ED - Gulyás, Gusztáv ED - Tibor, Kovács ED - Kásler, Miklós TI - Multidisciplanary approach to the treatment of breast cancer T2 - Principles and Practice of Oncoplastic Breast Surgery PB - Medicina Könyvkiadó CY - Budapest SN - 9789632267258 PY - 2019 SP - 89 EP - 96 PG - 8 UR - https://m2.mtmt.hu/api/publication/31156998 ID - 31156998 LA - English DB - MTMT ER - TY - JOUR AU - Újhelyi, Mihály AU - Pukancsik, Dávid AU - Kelemen, Péter Bertalan AU - Kovács, Eszter AU - Kenessey, István AU - Bak, Mihály AU - Kásler, Miklós AU - Kovács, T. AU - Mátrai, Zoltán Tamás TI - Barriers to organized mammography screening program in Hungary: a questionnaire-based study of 3 313 women JF - EUROPEAN JOURNAL OF SURGICAL ONCOLOGY J2 - EUR J SURG ONCOL (EJSO) VL - 45 PY - 2019 IS - 2 SP - e3 EP - e4 SN - 0748-7983 DO - 10.1016/j.ejso.2018.10.112 UR - https://m2.mtmt.hu/api/publication/31154105 ID - 31154105 LA - English DB - MTMT ER - TY - JOUR AU - Le, Ngoc Hoa Nha AU - Fillinger, János AU - Szanyi, Szilárd AU - Wichmann, B AU - Nagy, Zsófia Brigitta AU - Ivády-Szabó, Gabriella AU - Burai, M AU - Tarpay, Á AU - Pozsár, József AU - Pap, Á AU - Molnár, B AU - Csuka, O AU - Bak, Mihály AU - Tulassay, Zsolt AU - Szmola, Richárd TI - Analysis of microRNA expression in brush cytology specimens improves the diagnosis of pancreatobiliary cancer. JF - PANCREATOLOGY J2 - PANCREATOLOGY VL - 19 PY - 2019 IS - 6 SP - 873 EP - 879 PG - 7 SN - 1424-3903 DO - 10.1016/j.pan.2019.04.001 UR - https://m2.mtmt.hu/api/publication/30931650 ID - 30931650 AB - Malignant pancreatobiliary strictures are in many cases clinically indistinguishable and present a major problem to endoscopy specialists. Intraductal sampling procedures such as brush cytology are commonly used for diagnosis with a sensitivity that is low for a diagnostic test used in daily clinical practice. MicroRNA (miR) alterations detected in many cancers are disease-specific, which can be utilized in clinical applications. The aim of the present study was to analyze whether determination of miR expression levels in intraductal brush cytology specimens is a feasible approach to improve the diagnosis of pancreatobiliary cancer.Brush cytology specimens have been collected during endoscopic retrograde cholangio-pancreatography (ERCP) and analyzed by routine cytology and ancillary miR assays. Total RNA was extracted using the miRNeasy Mini Kit and the expression of miRs frequently dysregulated in pancreatobiliary cancer (miR-16, miR-21, miR-196a, miR-221) were analyzed by quantitative real-time PCR using RNU6B as internal control.Routine cytology resulted in no false positive diagnoses, however, the combined sensitivity remained at 53.8%. Expression (ΔCt values) of miR-16 (p = 0.0039), miR-196a (p = 0.0003) and miR-221 (p = 0.0049) showed a clear statistical significance between malignant and benign pancreatobiliary specimens (n = 35). Malignancy could be detected combining routine cytology and the miR-196a single marker expression levels with a sensitivity of 84.6% (92.9% in biliary strictures) with no false positives.The results offer the first direct demonstration that microRNAs are readily detectable in brush cytology specimens obtained during ERCP, and have the potential to help the cytological diagnosis of pancreatobiliary malignancy. LA - English DB - MTMT ER - TY - JOUR AU - Le, N AU - Fillinger, János AU - Szanyi, Szilárd AU - Wichmann, B AU - Nagy, ZB AU - Ivády-Szabó, Gabriella AU - Burai, M AU - Tarpay, Á AU - Pozsár, József AU - Pap, Á AU - Molnár, B AU - Csuka, O AU - Bak, Mihály AU - Tulassay, Z AU - Szmola, Richárd TI - Analysis Of MicRorna Expression in Brush Cytology Specimens Improves the Diagnosis of Pancreatobiliary Cancer JF - ENDOSCOPY J2 - ENDOSCOPY VL - 50 PY - 2018 IS - 4 SN - 0013-726X DO - 10.1055/s-0038-1637153 UR - https://m2.mtmt.hu/api/publication/30429890 ID - 30429890 LA - English DB - MTMT ER - TY - JOUR AU - Újhelyi, Mihály AU - Pukancsik, Dávid AU - Kelemen, Péter Bertalan AU - Kovács, Eszter AU - Kenessey, István AU - Bak, Mihály AU - Kásler, Miklós AU - Kovacs, Tibor Gyorgy AU - Mátrai, Zoltán Tamás TI - Barriers to Organized Mammography Screening Programs in Hungary: A Questionnaire-based Study of 3,313 Women. JF - ANTICANCER RESEARCH J2 - ANTICANCER RES VL - 38 PY - 2018 IS - 3 SP - 1727 EP - 1734 PG - 8 SN - 0250-7005 DO - 10.21873/anticanres.12408 UR - https://m2.mtmt.hu/api/publication/3343778 ID - 3343778 N1 - Departments of Breast and Sarcoma Surgery, Ráth György str. 7-9, Budapest, 1122, Hungary Departments of Radiological Diagnostics, Budapest, Hungary Departments of Cytopathology, Budapest, Hungary National Cancer Registry, National Institute of Oncology, Budapest, Hungary National Institute of Oncology, Budapest, Hungary Second Department of Pathology, Semmelweis University, Budapest, Hungary Breast Unit, Guy's Hospital, London, United Kingdom Cited By :1 Export Date: 22 May 2023 CODEN: ANTRD Correspondence Address: Újhelyi, M.; Departments of Breast and Sarcoma Surgery, Ráth György str. 7-9, Hungary; email: ujmisi@gmail.com AB - BACKGROUND/AIM: Despite well-organized Hungarian invitational mammography screening, participation rates have never reached 50%. This is similar to rates in Central Eastern Europe. In order to reduce breast cancer mortality, the participation rate should be at least 70%. This questionnaire-based study assessed the barriers associated with low adherence rates. MATERIALS AND METHODS: Women 45-65 years of age were interviewed by questionnaire containing 15 structured questions focused on socioeconomic status and barriers to screening. RESULTS: A total of 3,313 women completed the questionnaire. The main reasons for avoiding screening were work absenteeism (18.9%), fear of painful examination (18.39%), and poor understanding of mammography screening (14.94%). CONCLUSION: Education is required to increase awareness among women about the utility and availability of breast screening services. This report provides information on the appropriate level of intervention needed to increase screening participation in Hungary and other developing countries in Central Eastern Europe to reduce breast cancer-related mortality. LA - English DB - MTMT ER - TY - JOUR AU - Újhelyi, Mihály AU - Pukancsik, Dávid AU - Kelemen, Péter Bertalan AU - Sávolt, Ákos AU - Gődény, Mária AU - Kenessey, István AU - Mátrai, Tamás AU - Bak, Mihály AU - Kásler, Miklós AU - Mátrai, Zoltán Tamás TI - A lakossági emlőrákszűréstől való távolmaradás okai Magyarországon. 3313 eset kérdőíves vizsgálata JF - MAGYAR ONKOLÓGIA J2 - MAGYAR ONKOLÓGIA VL - 61 PY - 2017 IS - 1.suppl. SP - 47 EP - 48 PG - 2 SN - 0025-0244 UR - https://m2.mtmt.hu/api/publication/31616168 ID - 31616168 LA - Hungarian DB - MTMT ER - TY - GEN AU - Újhelyi, Mihály AU - Pukancsik, Dávid AU - Kelemen, Péter Bertalan AU - Sávolt, Ákos AU - Gődény, Mária AU - Kenessey, István AU - Mátrai, Tamás AU - Bak, Mihály AU - Kásler, Miklós AU - Mátrai, Zoltán Tamás TI - A lakossági emlőrákszűréstől való távolmaradás okai Magyarországon. 3313 eset kérdőíves vizsgálata PY - 2017 SP - 52 EP - 53 PG - 2 UR - https://m2.mtmt.hu/api/publication/31270003 ID - 31270003 N1 - online LA - Hungarian DB - MTMT ER -