TY  - JOUR
AU  - Mirdamadi, Seyedmohsen
AU  - Kothencz, Anna
AU  - Szűcs, Edina
AU  - Benyhe, Sándor
AU  - Szécsi, Mihály
AU  - Gáspár, Róbert
TI  - Non-genomic actions of sex hormones on pregnant uterine contractility in rats. An in vitro study at term
TS  - An in vitro study at term
JF  - LIFE SCIENCES
J2  - LIFE SCI
VL  - 263
PY  - 2020
PG  - 9
SN  - 0024-3205
DO  - 10.1016/j.lfs.2020.118584
UR  - https://m2.mtmt.hu/api/publication/31632111
ID  - 31632111
N1  - Funding Agency and Grant Number: Ministry of Human Capacities [20391-3/2018/FEKUSTRAT]; Stipendium Hungaricum Scholarship
            Funding text: This work was supported by the Ministry of Human Capacities. [Hungary grant 20391-3/2018/FEKUSTRAT] and the Stipendium Hungaricum Scholarship. Special thanks are due to Agnes Csiszarne for technical assistance in the experiments.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Herman, Bianka Edina
AU  - Gardi, János
AU  - Julesz, János
AU  - Tömböly, Csaba
AU  - Szánti-Pintér, Eszter
AU  - Fehér, Klaudia
AU  - Skoda-Földes, Rita
AU  - Szécsi, Mihály
TI  - Steroidal ferrocenes as potential enzyme inhibitors of the estrogen biosynthesis
JF  - BIOLOGIA FUTURA
J2  - BIOL FUTURA
VL  - 71
PY  - 2020
IS  - 3
SP  - 249
EP  - 264
PG  - 16
SN  - 2676-8615
DO  - 10.1007/s42977-020-00023-7
UR  - https://m2.mtmt.hu/api/publication/31365295
ID  - 31365295
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Herman, Bianka Edina
AU  - Kiss, Anita
AU  - Wölfling, János
AU  - Mernyák, Erzsébet
AU  - Szécsi, Mihály
AU  - Schneider, Gyula
TI  - Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1
JF  - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
J2  - J ENZYM INHIB MED CH
VL  - 34
PY  - 2019
IS  - 1
SP  - 1271
EP  - 1286
PG  - 16
SN  - 1475-6366
DO  - 10.1080/14756366.2019.1634064
UR  - https://m2.mtmt.hu/api/publication/30747981
ID  - 30747981
N1  - Export Date: 6 August 2019
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Jójárt, Rebeka
AU  - Traj, Péter
AU  - Kovács, Édua
AU  - Horváth, Ágnes
AU  - Schneider, Gyula
AU  - Szécsi, Mihály
AU  - Pál, Attila
AU  - Paragi, Gábor
AU  - Mernyák, Erzsébet
TI  - Synthesis, Biological Evaluation and Docking Studies of 13-Epimeric 10-fluoro- and 10-Chloroestra-1,4-dien-3-ones as Potential Aromatase Inhibitors
JF  - MOLECULES
J2  - MOLECULES
VL  - 24
PY  - 2019
IS  - 9
PG  - 18
SN  - 1420-3049
DO  - 10.3390/molecules24091783
UR  - https://m2.mtmt.hu/api/publication/30672179
ID  - 30672179
N1  - WoS:hiba:000469518100142 2020-01-10 07:35 cikkazonosító nem egyezik
LA  - English
DB  - MTMT
ER  - 

TY  - CONF
AU  - Jójárt, R
AU  - Pécsy, Sz
AU  - Szlávik, M
AU  - Szabó, V
AU  - Traj, P
AU  - Szécsi, Mihály
AU  - Laczkó-Rigó, Réka
AU  - Özvegy-Laczka, Cs
AU  - Mernyák, E
TI  - Synthesis and biochemical evaluation of novel 13?-estrone derivatives for targeted intracrine modulation of estrogen biosynthesis and transport
T2  - Serbian Biochemical Society - Eighth Conference
PY  - 2018
SP  - 137
EP  - 138
PG  - 2
UR  - https://m2.mtmt.hu/api/publication/30462098
ID  - 30462098
LA  - English
DB  - MTMT
ER  - 

TY  - CHAP
AU  - Jovanović-Šanta, SS
AU  - Herman, Bianka Edina
AU  - Zupkó, István
AU  - Kulmány, Ágnes Erika
AU  - Ocsovszki, I
AU  - Nikolić, AR
AU  - Savić, M
AU  - Oklješa, A
AU  - Szécsi, Mihály
ED  - Dávis, Szüts
ED  - László, Buday
ED  - Róbert, Hohol
ED  - Gergely, Szakáts
ED  - Gabriella, Bánfalvi
TI  - Screening of Antihormonal and Anticancer Potential of Heterocyclic Estrane Steroids
T2  - FEBS3+ Conference; From molecules to living systems
PB  - Diamond Congress Kft.
CY  - Veszprém
SN  - 9786155270475
PY  - 2018
SP  - 247
UR  - https://m2.mtmt.hu/api/publication/30462091
ID  - 30462091
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Jójárt, Rebeka
AU  - Pécsy, S.
AU  - Keglevich, György
AU  - Szécsi, Mihály
AU  - Laczkó-Rigó, Réka
AU  - Laczka, Csilla
AU  - Kecskeméti, Gábor
AU  - Mernyák, Erzsébet
TI  - Pd-Catalyzed microwave-assisted synthesis of phosphonated 13α-estrones as potential OATP2B1, 17β-HSD1 and/or STS inhibitors
JF  - BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
J2  - BEILSTEIN J ORG CHEM
VL  - 14
ET  - 0
PY  - 2018
SP  - 2838
EP  - 2845
PG  - 8
SN  - 1860-5397
DO  - 10.3762/bjoc.14.262
UR  - https://m2.mtmt.hu/api/publication/30331520
ID  - 30331520
AB  - Novel 2- or 4-phosphonated 13 alpha-estrone derivatives were synthesized via the Hirao reaction. Bromo regioisomers (2- or 4-) of 13 alpha-estrone and its 3-benzyl or 3-methyl ether were reacted with diethyl phosphite or diphenylphosphine oxide using Pd(PPh3)(4) as catalyst under microwave irradiation. The influence of the new compounds on the transport function of the organic anion transporting polypeptide OATP2B1 was investigated by measuring Cascade Blue uptake. Derivatives bearing a 3-benzyl ether function displayed substantial submicromolar OATP2B1 inhibitory activity. The inhibitory effects of the compounds on human placental steroid sulfatase (STS) and 17 beta-hydroxysteroid dehydrogenase type 1 isozyme (17 beta-HSD1) were investigated by in vitro radiosub-strate incubation methods. None of the test compounds inhibited the STS markedly. The structure-activity relationship evaluation revealed that 2-substituted 3-hydroxy derivatives are able to inhibit the 17 beta-HSD1 enzyme with submicromolar IC50 values. Dual OATP2B1 and 17 beta-HSD1 inhibitors have been identified.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Bacsa, Ildikó
AU  - Herman, Bianka Edina
AU  - Jójárt, Rebeka
AU  - Herman, Kevin Stefan
AU  - Wölfling, János
AU  - Schneider, Gyula
AU  - Varga, Mónika
AU  - Tömböly, Csaba
AU  - Rizner, Tea Lanisnik
AU  - Szécsi, Mihály
AU  - Mernyák, Erzsébet
TI  - Synthesis and structure–activity relationships of 2- and/or 4-halogenated 13β- and 13α-estrone derivatives as enzyme inhibitors of estrogen biosynthesis
JF  - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
J2  - J ENZYM INHIB MED CH
VL  - 33
PY  - 2018
IS  - 1
SP  - 1271
EP  - 1282
PG  - 12
SN  - 1475-6366
DO  - 10.1080/14756366.2018.1490731
UR  - https://m2.mtmt.hu/api/publication/27701563
ID  - 27701563
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kiss, Anita
AU  - Herman, Bianka Edina
AU  - Görbe, Tamás
AU  - Mernyák, Erzsébet
AU  - Molnár, Barnabás
AU  - Wölfling, János
AU  - Szécsi, Mihály
AU  - Schneider, Gyula
TI  - Synthesis of novel 17-triazolyl-androst-5-en-3-ol epimers via Cu(I)-catalyzed azide-alkyne cycloaddition and their inhibitory effect on 17α-hydroxylase/C17,20-lyase
JF  - STEROIDS
J2  - STEROIDS
VL  - 135
PY  - 2018
SP  - 79
EP  - 91
PG  - 13
SN  - 0039-128X
DO  - 10.1016/j.steroids.2018.03.006
UR  - https://m2.mtmt.hu/api/publication/3372993
ID  - 3372993
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Szánti-Pintér, Eszter
AU  - L, Maksó
AU  - Gömöry, Ágnes
AU  - J, Wouters
AU  - Herman, Bianka Edina
AU  - Szécsi, Mihály
AU  - Mikle, Gábor
AU  - Kollár, László
AU  - Skodáné Földes, Rita
TI  - Synthesis of 16α-amino-pregnenolone derivatives via ionic liquid-catalyzed aza-Michael addition and their evaluation as C17,20-lyase inhibitors
JF  - STEROIDS
J2  - STEROIDS
VL  - 123
PY  - 2017
SP  - 61
EP  - 66
PG  - 6
SN  - 0039-128X
DO  - 10.1016/j.steroids.2017.05.006
UR  - https://m2.mtmt.hu/api/publication/3227244
ID  - 3227244
N1  - WoS:hiba:000403131400009 2019-12-12 23:24 cím nem egyezik
LA  - English
DB  - MTMT
ER  -