TY - JOUR ED - Liptay, György / Selected by AU - Kiss, Tamás ED - Pretsch, Ernő / Interviewed person ED - Szántay, Csaba / Interviewed person ED - Lauri, Niinistö / Interviewed person ED - Fülöp, Ferenc / Interviewed person ED - Szántay, Csabáné / Interviewed person ED - Kertész, Éva / Interviewed person ED - Karasz, Gyöngyi / Interviewed person ED - Forgács, József / Interviewed person ED - Kiss, Tamás / Interviewed person TI - A közelmúlt és a jelen JF - MAGYAR KÉMIKUSOK LAPJA J2 - MAGY KEM LAP VL - 76 PY - 2021 IS - 4 SP - 112 EP - 116 PG - 5 SN - 0025-0163 UR - https://m2.mtmt.hu/api/publication/31966634 ID - 31966634 N1 - "...Ezúttal, rendhagyó módon, az MKL mostani főszerkesztőjének néhány interjújából válogattunk. Kiss Tamás 2008-ban vette át a főszerkesztői posztot, és számos interjút készített a főszerkesztői munka mellett...kutatókkal és tanárokkal készült interjúiból idézünk néhányat szemelvényszerűen." LA - Hungarian DB - MTMT ER - TY - JOUR AU - Keglevich, Péter AU - Ábrányi-Balogh, Péter AU - Szigetvári, Áron AU - Szántay, Csaba (Ifj.) AU - Szántay, Csaba AU - Hazai, László TI - Studies on the mechanism of quaternization of the catharanthine part of vinblastine and vincristine JF - TETRAHEDRON LETTERS J2 - TETRAHEDRON LETT VL - 57 PY - 2016 IS - 15 SP - 1672 EP - 1677 PG - 6 SN - 0040-4039 DO - 10.1016/j.tetlet.2016.03.004 UR - https://m2.mtmt.hu/api/publication/3041580 ID - 3041580 N1 - Department of Organic Chemistry and Technology, University of Technology and Economics, H-1111 Budapest, Gellért tér 4., Hungary Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, H-1519 Budapest, PO Box 286, Hungary Spectroscopic Research Division, Gedeon Richter Plc., H-1475 Budapest 10, PO Box 27, Hungary Export Date: 12 May 2021 CODEN: TELEA Correspondence Address: Hazai, L.; Department of Organic Chemistry and Technology, H-1111 Budapest, Hungary; email: hazai@mail.bme.hu Chemicals/CAS: catharanthine, 2468-21-5; diethylzinc, 557-20-0; nitrogen, 7727-37-9; vinblastine, 865-21-4; vincristine, 57-22-7 Funding details: Gedeon Richter, TÁMOP 4.2.1/B-09/1/KMR-2010-0002 Funding text 1: The authors are grateful to Gedeon Richter Plc for financial assistance. The research work has been accomplished in the framework of the ‘BME R+D+I project’ supported by the grant TÁMOP 4.2.1/B-09/1/KMR-2010-0002 . Department of Organic Chemistry and Technology, University of Technology and Economics, H-1111 Budapest, Gellért tér 4., Hungary Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, H-1519 Budapest, PO Box 286, Hungary Spectroscopic Research Division, Gedeon Richter Plc., H-1475 Budapest 10, PO Box 27, Hungary Export Date: 4 June 2021 CODEN: TELEA Correspondence Address: Hazai, L.; Department of Organic Chemistry and Technology, H-1111 Budapest, Hungary; email: hazai@mail.bme.hu Chemicals/CAS: catharanthine, 2468-21-5; diethylzinc, 557-20-0; nitrogen, 7727-37-9; vinblastine, 865-21-4; vincristine, 57-22-7 Funding details: Gedeon Richter, TÁMOP 4.2.1/B-09/1/KMR-2010-0002 Funding text 1: The authors are grateful to Gedeon Richter Plc for financial assistance. The research work has been accomplished in the framework of the ‘BME R+D+I project’ supported by the grant TÁMOP 4.2.1/B-09/1/KMR-2010-0002 . Funding Agency and Grant Number: Gedeon Richter Plc; [TAMOP 4.2.1/13-09/1/KMR-2010-0002] Funding text: The authors are grateful to Gedeon Richter Plc for financial assistance. The research work has been accomplished in the framework of the 'BME R+D+I project' supported by the grant TAMOP 4.2.1/13-09/1/KMR-2010-0002. LA - English DB - MTMT ER - TY - JOUR AU - Keglevich, Péter AU - Hazai, László AU - Kalaus, György AU - Szántay, Csaba TI - Új, daganatellenes hatású, ciklopropángyűrűt tartalmazó vinblasztinszármazékok előállítása JF - MAGYAR KÉMIAI FOLYÓIRAT - KÉMIAI KÖZLEMÉNYEK (1997-) J2 - MAGY KÉM FOLY KÉM KÖZL VL - 121 PY - 2015 IS - 4 SP - 136 EP - 141 PG - 6 SN - 1418-9933 UR - https://m2.mtmt.hu/api/publication/2986730 ID - 2986730 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Ilkei, Viktor AU - Bana, Péter AU - Tóth, Flórian AU - Palló, Anna AU - Holczbauer, Tamás AU - Czugler, Mátyás AU - Sánta, Zsuzsanna AU - Dékány, Miklós AU - Szigetvári, Áron AU - Hazai, László AU - Szántay, Csaba (Ifj.) AU - Szántay, Csaba AU - Kalaus, György TI - A simple synthesis of bannucine and 5’-epibannucine from (-)-vindoline JF - TETRAHEDRON J2 - TETRAHEDRON VL - 71 PY - 2015 IS - 51 SP - 9579 EP - 9586 PG - 8 SN - 0040-4020 DO - 10.1016/j.tet.2015.10.020 UR - https://m2.mtmt.hu/api/publication/2986044 ID - 2986044 N1 - Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Gellért tér 4, Budapest, H-1111, Hungary XiMo Hungary Ltd., Záhony utca 7, Budapest, H-1031, Hungary Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2, Budapest, H-1117, Hungary Spectroscopic Research Division, Gedeon Richter Plc., Gyömroi út 19-21, Budapest, H-1103, Hungary Cited By :2 Export Date: 12 May 2021 CODEN: TETRA Correspondence Address: Ilkei, V.; Department of Organic Chemistry and Technology, Gellért tér 4, Hungary; email: vilkei@mail.bme.hu Chemicals/CAS: aspidospermine, 466-49-9; carbon, 7440-44-0; proton, 12408-02-5, 12586-59-3; succinimide, 123-56-8; vindoline, 2182-14-1 Funding text 1: The authors are grateful to Gedeon Richter Plc. for providing (−)-vindoline and for the financial assistance. The authors are also grateful to the National Institutes of Health (NIH) for the biological testing of the samples. Funding Agency and Grant Number: Gedeon Richter Plc. Funding text: The authors are grateful to Gedeon Richter Plc. for providing (-)-vindoline and for the financial assistance. The authors are also grateful to the National Institutes of Health (NIH) for the biological testing of the samples. LA - English DB - MTMT ER - TY - JOUR AU - Keglevich, Péter AU - Hazai, László AU - Kalaus, György AU - Szántay, Csaba TI - Cyclopropanation of Some Alkaloids JF - PERIODICA POLYTECHNICA-CHEMICAL ENGINEERING J2 - PERIOD POLYTECH CHEM ENG VL - 59 PY - 2015 IS - 1 SP - 3 EP - 15 PG - 13 SN - 0324-5853 DO - 10.3311/PPch.7257 UR - https://m2.mtmt.hu/api/publication/2910367 ID - 2910367 N1 - Admin megjegyzés-24738140 #JournalID1# Name: PERIOD POLYTECH-CHEM ISSN: 0324-5853 #JournalID2# Admin megjegyzés-24738413 #JournalID1# Name: PERIOD POLYTECH-CHEM ISSN: 0324-5853 #JournalID2# Admin megjegyzés-24738991 #JournalID1# Name: PERIOD POLYTECH-CHEM ISSN: 0324-5853 #JournalID2# Admin megjegyzés-24739359 #JournalID1# Name: PERIOD POLYTECH-CHEM ISSN: 0324-5853 #JournalID2# Admin megjegyzés-24740732 #JournalID1# Name: PERIOD POLYTECH-CHEM ISSN: 0324-5853 #JournalID2# Cited By :4 Export Date: 12 May 2021 Correspondence Address: Szántay, C.; Department of Organic Chemistry and Technology, P. O. B. 91, Hungary; email: szantay@mail.bme.hu Cited By :4 Export Date: 16 May 2021 Correspondence Address: Szántay, C.; Department of Organic Chemistry and Technology, P. O. B. 91, Hungary; email: szantay@mail.bme.hu Funding Agency and Grant Number: OTKA (Hungarian Academic Research Found)Orszagos Tudomanyos Kutatasi Alapprogramok (OTKA) [K 68734]; Gedeon Richter Plc Funding text: The authors are grateful to OTKA (Hungarian Academic Research Found Grant K 68734) and to Gedeon Richter Plc for financial assistance. Cited By :5 Export Date: 16 August 2021 Correspondence Address: Szántay, C.; Department of Organic Chemistry and Technology, P. O. B. 91, Hungary; email: szantay@mail.bme.hu AB - New derivatives of natural compounds, galanthamine using in treatment of Alzheimer's disease and antitumor dimer alkaloids vinblastine and vincristine were synthesized. In the course of the reaction between galanthamine and diazomethane in the presence of a catalyst, such as palladium (I!) acetate or copper(I) bromide, methylene insertion into the aromatic ring was observed instead of the expected cyclopropanation of the carbon-carbon double bond New vindoline derivatives conjugated with amino acid esters were prepared In Simmons-Smith reaction vinblastine and vincristine cyclopropanated in the carbon carbon double bond in position 14 and 15 of the vindoline monomer were obtained New dimer alkaloids showed significant inhibiting effects in several tumor cell lines. LA - English DB - MTMT ER - TY - JOUR AU - Keglevich, Péter AU - Hazai, László AU - Dubrovay, Zs AU - Sánta, Zs AU - Dékány, M AU - Szántay, Csaba (Ifj.) AU - Kalaus, György AU - Szántay, Csaba TI - Bisindole alkaloids condensed with a cyclopropane ring, Part 2. Cyclopropano-vinorelbine and its derivatives JF - HETEROCYCLES J2 - HETEROCYCLES VL - 90 PY - 2015 IS - 1 SP - 316 EP - 326 PG - 11 SN - 0385-5414 DO - 10.3987/COM-14-S(K)20 UR - https://m2.mtmt.hu/api/publication/2829430 ID - 2829430 N1 - Funding Agency and Grant Number: Gedeon Richter Plc Funding text: The authors are grateful to Gedeon Richter Plc for financial assistance. LA - English DB - MTMT ER - TY - PAT AU - Szántay, Csaba AU - Hazai, László AU - Kalaus, György AU - Keglevich, Péter TI - New bis-indole alkaloids as anticancer drugs PY - 2014 UR - https://m2.mtmt.hu/api/publication/3415399 ID - 3415399 LA - English DB - MTMT ER - TY - JOUR AU - Ilkei, Viktor AU - Faragó, Kornél AU - Sánta, Zsuzsanna AU - Dékány, Miklós AU - Hazai, László AU - Szántay, Csaba (Ifj.) AU - Szántay, Csaba AU - Kalaus, György TI - The First Synthesis of Sessiline JF - INTERNATIONAL JOURNAL OF ORGANIC CHEMISTRY J2 - IJOC VL - 4 PY - 2014 IS - 5 SP - 309 EP - 313 PG - 5 SN - 2161-4687 DO - 10.4236/ijoc.2014.45033 UR - https://m2.mtmt.hu/api/publication/2840555 ID - 2840555 AB - Sessiline is an alkaloid which was recently isolated from the fruits of Acanthopanax sessiliflorus. The molecule contains two five-membered heterocyclic units joined together by an acylaminocarbinol-ether type bond. Here, we describe the first, simple synthesis of sessiline from 5-hydroxypyrrolidin-2-one and 5-hydroxymethylfurfural, which are prepared from succinimide and furfuryl alcohol, respectively. The coupling reaction takes place on moderate heating under neat conditions. LA - English DB - MTMT ER - TY - JOUR AU - Keglevich, Péter AU - Keglevich, András Imre AU - Hazai, László AU - Kalaus, György AU - Szántay, Csaba TI - Natural Compounds Containing a Condensed Cyclopropane Ring. Natural and Synthetic Aspects JF - CURRENT ORGANIC CHEMISTRY J2 - CURR ORG CHEM VL - 18 PY - 2014 IS - 15 SP - 2037 EP - 2042 PG - 6 SN - 1385-2728 DO - 10.2174/1385272819666140721190257 UR - https://m2.mtmt.hu/api/publication/2836711 ID - 2836711 N1 - Cited By :15 Export Date: 16 May 2021 CODEN: CORCF Correspondence Address: Szántay, C.; Department of Organic Chemistry and Technology, Szt. Gellért tér 4, Hungary Cited By :15 Export Date: 4 June 2021 CODEN: CORCF Correspondence Address: Szántay, C.; Department of Organic Chemistry and Technology, Szt. Gellért tér 4, Hungary AB - The carbon-carbon double bond offers a possibility to incorporate a cyclopropane ring into a molecule. The special electronic nature of the cyclopropane ring can significantly change the electronic and biological properties of the new derivatives. Herein we present natural compounds containing a fused cyclopropane ring and natural compounds condensed with a cyclopropane ring synthetically. LA - English DB - MTMT ER - TY - JOUR AU - Keglevich, Péter AU - Hazai, László AU - Dubrovay, Zs AU - Dékány, M AU - Szántay, Csaba (Ifj.) AU - Kalaus, György AU - Szántay, Csaba TI - Bisindole alkaloids condensed with a cyclopropane ring. Part 1. 14,15-Cyclopropanovinblastine and -vincristine JF - HETEROCYCLES J2 - HETEROCYCLES VL - 89 PY - 2014 IS - 3 SP - 653 EP - 668 PG - 16 SN - 0385-5414 DO - 10.3987/COM-13-12918 UR - https://m2.mtmt.hu/api/publication/2559508 ID - 2559508 N1 - Department of Organic Chemistry and Technology, University of Technology and Economics, Gellért tér 4., H-1111 Budapest, Hungary Spectroscopic Research Division, Gedeon Richter Plc., 10, P. O. Box 27, H-1475 Budapest, Hungary Cited By :7 Export Date: 12 May 2021 CODEN: HTCYA Department of Organic Chemistry and Technology, University of Technology and Economics, Gellért tér 4., H-1111 Budapest, Hungary Spectroscopic Research Division, Gedeon Richter Plc., 10, P. O. Box 27, H-1475 Budapest, Hungary Cited By :7 Export Date: 16 May 2021 CODEN: HTCYA Funding Agency and Grant Number: Gedeon Richter Plc Funding text: The authors are grateful to Gedeon Richter Plc for financial assistance. LA - English DB - MTMT ER -