TY - CONF AU - Borbély, Noémi AU - Pamjav, Horolma AU - Egyed, Balázs AU - Máthé, István AU - Szécsényi-Nagy, Anna TI - Uniparental genetic diversity of three Hungarian-speaking isolated communities in the Carpathian Basin T2 - Programme and abstract book 12th Haploid Markers 2023 PY - 2023 SP - 78 UR - https://m2.mtmt.hu/api/publication/34580135 ID - 34580135 LA - English DB - MTMT ER - TY - CHAP AU - Pamjav, Horolma ED - Neparáczki, Endre TI - A magyar népesség genetikai összetétele apai ágon T2 - Magyar őstörténeti műhelybeszélgetés II. PB - Magyarságkutató Intézet CY - Budapest SN - 9786156117663 T3 - A Magyarságkutató Intézet Kiadványai, ISSN 2677-0261 ; 55. PY - 2022 SP - 39 EP - 66 PG - 28 DO - 10.53644/MKI.MAOSMB.2022.39 UR - https://m2.mtmt.hu/api/publication/33695386 ID - 33695386 AB - Az emberiség történelme szorosan összefügg a népvándorlás történetével. A genetikai sokféleség mintázatai információt nyújtanak a népesség történetéről, mivel minden jelentősebb demográfiai esemény nyomot hagyott a populációk genomiális sokféleségében. Ezek a demográfiai nyomok nemzedékről nemzedékre adódnak át, így a mai emberek genomja demográfiai történetüket tükrözi. A történelmi és régészeti adatok alapján a honfoglaló magyarok keletről érkeztek – hét törzsből álló szövetségben –, és úgy 895 körül véglegesen letelepedtek a Kárpát-medencében. Jelenlegi tudásunk alapján pontosan nem tudjuk megnevezni, hogy a honfoglaló magyarok magja konkrétan melyik földrajzi régióból indulhatott nyugat felé tartó útjára, azonban bizonyos – dél-szibériai eredetű – anyai és apai leszármazási vonalak jelenléte a recens magyar populációkban és a honfoglalás kori régészeti csontmintákban arra enged következtetni, hogy valahol Dél-Szibéria és a mai Mongólia területére mutat. Foglaljuk el képzeletünk repülő léghajóját, amelyről lepillantva láthatjuk, amint ezen feltételezett népcsoport – bizonyára eléggé szervezetten – családjával élte életét a vagyontárgyat képező állatállománnyal együtt és mindig egy kicsit tovább haladhatott – természetesen nyugat felé – a legfrissebb legelőterület kiválasztása miatt. Ki tudja, hány évszázad alatt tették meg az utat a Kárpát-medencéig… Természetesen útközben békésen kapcsolatba kerülhettek más népcsoportokkal, vagy egyeseket meghódítottak, talán behódoltak mások is. Ezen események következtében genetikai állományukba bekerülhettek azon népek genetikai nyomai, akikkel érintkezésbe kerültek, amellett megtartották az eredeti génállományt is. Ha a honfoglalók GPS-koordináták alapján cserkészték volna be a Kárpát-medencét éjjel-nappal menetelve, vagy repülőgépre szálltak volna fel, akkor kizárólag csak az eredeti génállományukat hozták volna az új honba. Talán voltak közöttük „felderítők”, akik előre mentek és kifürkészték, hogy hány napnyi vagy hónapnyi távolságra milyen területek vannak és kik laknak ott, ha egyáltalán a hírekkel visszatértek. Elgondolkodtató, hogy a honfoglalók miért pont a Kárpát-medencében maradtak és miért nem mentek tovább. Legészszerűbb válasz erre az lehetett, hogy meglehetősen alkalmasnak vélték az új területet (folyók, völgyek, alföldek és hegyek) az állatok legeltetésére és földművelésre, ugyanakkor valószínűleg olyan körülmények is közrejátszottak, hogy az új jövevényeket nem üldözték el a helybeliek a kiválasztott honból. Ezzel a kis történettel próbáltam emberközelivé tenni e tudományág szakmai berkeiben esetleg tájékozatlan személyeknek a túl szakmainak tűnő őstörténeti genetikai eredményeket, amelyek a későbbiek során következnek. LA - Hungarian DB - MTMT ER - TY - CHAP AU - Borbély, Noémi AU - Koppány, Kerestély AU - Benkő, Elek AU - Sófalvi, András AU - Zsolt, Nyárádi AU - Pamjav, Horolma AU - Szécsényi-Nagy, Anna ED - Balassa, Kinga ED - Balog, Luca Eszter ED - László, Loretta ED - Hamar, Renáta ED - Nyitray, László TI - Genetic study of modern and medieval Székely Land T2 - Annual Meeting of the Eötvös Loránd University Doctoral School of Biology SN - 9786150168364 PY - 2022 SP - 23 EP - 23 PG - 1 UR - https://m2.mtmt.hu/api/publication/33615692 ID - 33615692 AB - We examine DNA of ancient and modern-day Székely individuals from the Udvarhelyszék- region, in order to gather genetic information from Hungarian-speaking long-time residents of Transylvania. The aim of the research is to unveil genetic relationships between ancient and recent populations not only from the Carpathian Basin basin but from the historically relevant areas. We generated high quality uniparental and whole-genome data, aiming to monitor the continuity and relationships of the region’s populations. The ancient sample set we analysed contains nearly a hundred medieval (12- 16. century) individuals from the region of Székelyudvarhely, mostly from church-related burials, whereas the modern sample set consists of 115 Hungarian-speaking Székely individuals originating from isolated villages of the same region. We analyzed maternal lineages with whole mtDNA next-generation sequencing, compared the results to published modern and ancient mitogenomic datasets. The majority of the modern and medieval Székely population belongs to European mtDNA haplogroups, but the presence of a small number of Asian-derived haplotypes is evident. Phylogenetic analyses confirmed the presumed eastern origin of certain lineages and in some cases, they can be linked to ancient DNA data of early Hungarians. Among the Y-chromosome haplogroups mostly the European-related ones are dominant and a few samples are assigned to haplogroups with Asian-origin, which may reflect some level of Central Asian connections. The whole genome results demonstrate the homogeneity and continuity of the medieval Székely population up to the modern times. This study is funded by the NKFIH FK-127938 research grant. LA - English DB - MTMT ER - TY - JOUR AU - Neparáczki, Endre AU - Kis, Luca AU - Maróti, Zoltán AU - Kovács, Bence AU - Varga, Gergely István AU - Makoldi, Miklós Zsombor AU - Pamjav, Horolma AU - Teiszler, Éva AU - Tihanyi, Balázs AU - Nagy, Péter L. AU - Maár, Kitti AU - Gyenesei, Attila AU - Schütz, Oszkár AU - Dudás, Eszter AU - Török, Tibor AU - Pascuttini-Juraga, Vesna AU - Peharda, Ivančica AU - Vizi, László Tamás AU - Horváth-Lugossy, Gábor AU - Kásler, Miklós TI - The genetic legacy of the Hunyadi descendants JF - HELIYON J2 - HELIYON VL - 8 PY - 2022 IS - 11 PG - 8 SN - 2405-8440 DO - 10.1016/j.heliyon.2022.e11731 UR - https://m2.mtmt.hu/api/publication/33257861 ID - 33257861 N1 - Cited By :1 Export Date: 19 April 2023 AB - The Hunyadi family is one of the most influential families in the history of Central Europe in the 14th–16th centuries. The family’s prestige was established by Johannes Hunyadi, a Turk-beater who rose to the position of governor of the Kingdom of Hungary. His second son, Matthias Hunyadi, became the elected ruler of the Kingdom of Hungary in 1458. The Hunyadi family had unknown origin. Moreover, Matthias failed to found a dynasty because of lacking a legitimate heir and his illegitimate son Johannes Corvinus was unable to obtain the crown. His grandson, Christophorus Corvinus, died in childhood, thus the direct male line of the family ended. In the framework of on interdisciplinary research, we have determined the whole genome sequences of Johannes Corvinus and Christophorus Corvinus by next-generation sequencing technology. Both of them carried the Y-chromosome haplogroup is E1b1b1a1b1a6a1c ~, which is widespread in Eurasia. The father-son relationship was verified using the classical STR method and whole genome data. Christophorus Corvinus belongs to the rare, sporadically occurring T2c1þ146 mitochondrial haplogroup, most frequent around the Mediterranean, while his father belongs to the T2b mitochondrial haplogroup, widespread in Eurasia, both are consistent with the known origin of the mothers. Archaeogenomic analysis indicated that the Corvinus had an ancient European genome composition. Based on the reported genetic data, it will be possible to identify all the other Hunyadi family member, whose only known grave site is known, but who are resting assorted with several other skeletons. LA - English DB - MTMT ER - TY - GEN AU - Borbély, Noémi AU - Szeifert, Bea AU - Kerestély, Koppány AU - Pamjav, Horolma AU - Nyárádi, Zsolt AU - Egyed, Balázs AU - Sófalvi, András AU - Gál, Szilárd Sándor AU - Benkő, Elek AU - Szécsényi-Nagy, Anna TI - Investigating the archaic and modern-day Székely gene pool around Székelyudvarhely PY - 2022 SP - 488 PG - 1 UR - https://m2.mtmt.hu/api/publication/33227423 ID - 33227423 AB - We examine DNA from archaic and modern-day Székely samples from the region of Székelyudvarhely to expand our knowledge about Hungarian population genetics relationships and complete the genetic map of the Carpathian Basin with high quality uniparental (whole mitogenome and 17-23 Y-STR data) and full-genome data. The modern sample set we analyzed includes more than a hundred Hungarian-speaking Székely individuals from isolated villages near the town Székelyudvarhely. The donors’ maternal and paternal ancestry was thoroughly documented in order to exclude the effect of population migration in the last 100-150 years and to avoid sampling of close relatives. The archaic sample set contains nearly a hundred medieval (12- 15/16. century) individuals from the region of Székelyudvarhely (Székelyudvarhely, Székelykeresztúr, Fenyéd, Kányád, Nagygalambfalva, Patakfalva, Máréfalva, Bögöz) mostly from church-related burials. We analyzed maternal lineages with whole mtDNA next-generation sequencing, and the results were compared to published modern and ancient mitogenomic datasets. The majority of the modern and archaic Székely population can be assigned to European mtDNA haplogroups, but the presence of Asian haplotypes is not negligible either. Phylogenetic analyses confirmed the presumed eastern origin of certain lineages and in some cases, they can be linked to ancient DNA data of early Hungarians. In the modern data set, we found mostly European-related Y-haplogroups and the smaller proportion of the samples belonged to haplogroups with Asian-origin. These are the few Y-haplotypes that may reflect a Central Asian connection. Further observations are aimed to achieve from comparative analyses of the paternal lineages and the thorough analysis of whole-genome data. Through these studies, we can monitor the continuity and relationships of the region’s populations. This study was funded by the NKFIH FK-127938 research grant. LA - English DB - MTMT ER - TY - CHAP AU - Borbély, Noémi AU - Gerber, Dániel AU - Szeifert, Bea AU - Pamjav, Horolma AU - Mende, Balázs Gusztáv AU - Egyed, Balázs AU - Szécsényi-Nagy, Anna ED - László, Buday ED - Miklós, Erdélyi ED - Beáta, Lontay ED - József, Mihály ED - Sinka, Rita ED - László, Virág ED - Gergely, Szakáts ED - Attila, Varga TI - Towards building the genetic map of the Carpathian Basin T2 - Hungarian Molecular Life Sciences 2021 PB - Diamond Congress Kft. CY - Eger SN - 9786155270673 PY - 2021 SP - 199 EP - 199 PG - 1 UR - https://m2.mtmt.hu/api/publication/32672269 ID - 32672269 AB - Our research was aimed at mapping the genetic structure and paternal gene pool of the early 20th/ late 19th-century population of the Carpathian Basin, as part of which we performed full mtDNA-based and Y-chromosomal genotyping of samples collected from present-day Hungarian-speaking villages located in Transylvania, Drávaszög in Croatia, and Zobor-region in Slovakia. Our basic assumption was that we reconstruct the uniparental gene pool of the Hungarian speaking populations that existed 100- 150 years ago by finding elderly sample donors living in isolated villages and documenting their genealogies carefully. The aim of the research was to monitor any regional genetic structure discrepancies of the Hungarian speaking population and to confirm preliminary uniparental genetic studies that revealed an increased number of Eastern Eurasian lineages in isolated populations, compared to populations of larger cities. Our partial results from the Sekler population indicate a mainly West-Eurasian uniparental makeup that also points to limited admixture with neighboring populations. European mtDNA haplogroups characterize the majority of the population, but differently from the Hungarian-speaking population in Hungary, as there is a perceptibly higher proportion of Eastern Asian haplotypes. Phylogenetic analyses confirmed the presumed eastern origin of certain maternal lineages and in some particular cases, they can also be linked to ancient DNA data of early Hungarians. So far we have examined 286 newly sequenced whole mitochondrial genomes and Y chromosome STR and SNP profiles of 214 men from the three regions. Our follow-up plan is to generate whole-genome data to receive more detailed inferences on the origin and connection of ancient and modern-day Hungarian-speaking populations. LA - English DB - MTMT ER - TY - JOUR AU - Pamjav, Horolma AU - Krizsan, Krisztina TI - Biologia futura: confessions in genes JF - BIOLOGIA FUTURA J2 - BIOL FUTURA VL - 71 PY - 2020 IS - 4 SP - 435 EP - 441 PG - 7 SN - 2676-8615 DO - 10.1007/s42977-020-00049-x UR - https://m2.mtmt.hu/api/publication/31684563 ID - 31684563 AB - Y-DNA and mtDNA have been a widely used tool not only in forensic genetic applications but in human evolutionary and population genetic studies. Its paternal or maternal inheritance and lack of recombination have offered the opportunity to explore genealogical relationships among individuals and to study the frequency differences of paternal and maternal clades among human populations at continental and regional levels. It is unbelievable, but true, that the disadvantages of paternal and maternal lineages in forensic genetic studies, i.e., everyone within a family have the same paternal or maternal haplotype and haplogroup, become advantages in human evolutionary studies, i.e., reveal the genetic history of successful mothers and successful fathers. Thanks to these amazing properties of haploid markers, they provide tools for mapping the migration routes of human populations during prehistoric and historical periods, separately as maternal and paternal lineages, and together as the genetic history of a population. LA - English DB - MTMT ER - TY - JOUR AU - Csáky, Veronika AU - Gerber, Dániel AU - Koncz, István AU - Csiky, Gergely AU - Mende, Balázs Gusztáv AU - Szeifert, Bea AU - Egyed, Balázs AU - Pamjav, Horolma AU - Marcsik, Antónia AU - Molnár, Erika AU - Pálfi, György AU - Gulyás, András Zoltán AU - Kovacsóczy, Bernadett AU - Lezsák, Gabriella AU - Lőrinczy, Gábor AU - Szécsényi-Nagy, Anna AU - Vida, Tivadar TI - Genetic insights into the social organisation of the Avar period elite in the 7th century AD Carpathian Basin JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 10 PY - 2020 IS - 1 PG - 14 SN - 2045-2322 DO - 10.1038/s41598-019-57378-8 UR - https://m2.mtmt.hu/api/publication/31041051 ID - 31041051 N1 - M. Lezsák Gabriella: The Avar-period cemetery of Kunszállás-Fülöpjakab (Bács-Kiskun county, Hungary). LA - English DB - MTMT ER - TY - JOUR AU - Dudás, Eszter AU - Susa, Éva AU - Pamjav, Horolma AU - Szabolcsi, Zoltán TI - Identification of World War II bone remains found in Ukraine using classical anthropological and mitochondrial DNA results JF - INTERNATIONAL JOURNAL OF LEGAL MEDICINE J2 - INT J LEGAL MED VL - 134 PY - 2020 SP - 487 EP - 489 PG - 3 SN - 0937-9827 DO - 10.1007/s00414-019-02026-z UR - https://m2.mtmt.hu/api/publication/30876979 ID - 30876979 N1 - Department of Reference Samples Analysis, Hungarian Institute for Forensic Sciences, Institute of Forensic Genetics, Gyorskocsi u. 25, Budapest, H-1027, Hungary Anthropologist, Institute of National Heritage, Fiumei str. 16-18, Budapest, 1086, Hungary Georgikon Faculty, Department of Animal Sciences and Animal Husbandry, University of Pannonia, Deák Ferenc u. 16, Keszthely, H-8361, Hungary Cited By :7 Export Date: 18 November 2022 CODEN: IJLME Correspondence Address: Szabolcsi, Z.; Georgikon Faculty, Deák Ferenc u. 16, Hungary; email: szabzoltan@gmail.com AB - Gyula Ágner was a Royal Hungarian First Lieutenant (1st Lt.) during the World War II and died at 30 years old due to a mine shrapnel injury on 27 April 1944 in Luczky, Ukraine. In October 2014, the Hungarian Ministry of Defence exhumated the remains then transported them to Budapest in Hungary. Classical anthropological methods were used to determine morphological gender, height and age at death; furthermore, metrical and pathological characters were also analysed. Determination of maternal lineage was the only solution to examine the possible relationship of the bone fragments. Gyula Ágner did not have direct descendants, thus the living niece of the deceased (his sister's daughter) served as the reference person during the investigations. Hypervariable regions of the mtDNA control region (HV1, HV2 and HV3) were amplified by Qiagen® Multiplex PCR Kit in different monoplex reactions. The results of the anthropological and genetical analysis supported the hypothesis that the bone remains belong to Gyula Ágner. LA - English DB - MTMT ER - TY - JOUR AU - Pamjav, Horolma AU - Dudás, E AU - Krizsán, K AU - Galambos, A TI - A Y-chromosomal study of Mansi population from Konda River Basin in Ural JF - FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES J2 - FORENSIC SCI INT-GEN SUPPL SER VL - 7 PY - 2019 IS - 1 SP - 602 EP - 603 PG - 2 SN - 1875-1768 DO - 10.1016/j.fsigss.2019.10.106 UR - https://m2.mtmt.hu/api/publication/30869716 ID - 30869716 LA - English DB - MTMT ER -