@article{MTMT:3106886, title = {Az emlőrák szisztémás kezelése. szakmai útmutatás}, url = {https://m2.mtmt.hu/api/publication/3106886}, author = {Horváth, Zsolt and Boér, Katalin and Dank, Magdolna and Kahán, Zsuzsanna and Kocsis, Judit and Kövér, Erika and Pajkos, G and Piko, B and Rubovszky, Gábor and Eckhardt, Sándor}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {60}, unique-id = {3106886}, issn = {0025-0244}, abstract = {The article presents the practice guideline of systemic treatment of breast cancer and recommendations of the 3rd Hungarian Breast Cancer Consensus Conference. It reflects the recent international guidelines (ESMO, NCCN, ABC2, St Gallen's) irrespectively of the current financial opportunities. Here we follow the early - locally advanced - locally relapsed - metastatic breast cancer line for didactic considerations and we discuss the different subgroups of breast cancer based on hormone receptor and HER2 receptor status. Diagnosis and treatment options of rare clinical entities are summarised at the end of the paper.}, year = {2016}, eissn = {2060-0399}, pages = {241-257}, orcid-numbers = {Horváth, Zsolt/0000-0002-5376-7737; Boér, Katalin/0000-0002-5101-7289; Dank, Magdolna/0000-0002-4442-8733; Kahán, Zsuzsanna/0000-0002-5021-8775; Kocsis, Judit/0000-0002-6110-9750; Rubovszky, Gábor/0000-0003-1723-5589} } @article{MTMT:3371919, title = {Célzott daganatterápiák : új utak a daganatok gyógyszeres kutatásában}, url = {https://m2.mtmt.hu/api/publication/3371919}, author = {Eckhardt, Sándor}, journal-iso = {MEDICAL TRIBUNE}, journal = {MEDICAL TRIBUNE}, volume = {10}, unique-id = {3371919}, issn = {1589-1283}, abstract = {Az utóbbi évtizedekben a sejtműködésre vonatkozó ismereteink rohamosan bővültek. Többet tudunk például a DNS-ről, az RNS-ről, a proteinekről, a jelátviteli folyamatokról vagy a sejt genetikus profiljáról. Érthető tehát, hogy a rák kezelése is irányt váltott: azokat a sejtműködési zavarokat "vette célba", amelyek daganat keletkezéséhez vezethetnek. E törekvések viselik a "célzott terápia" nevet.}, keywords = {terápia; daganatok; DAGANATELLENES SZEREK}, year = {2012}, pages = {10} } @article{MTMT:1695701, title = {Inflammatory breast cancer-comparing the effectivity of preoperative docetaxel-epirubicine protocol to conventional antracycline-containing chemotherapy to achieve clinical benefit and complete pathological response}, url = {https://m2.mtmt.hu/api/publication/1695701}, author = {Horváth, Zsolt and Torday, László and Hitre, Erika and Ganofszky, E and Juhos, E and Czegledi, F and Urbán, László and Polgár, Csaba and Láng, István and Eckhardt, Sándor and Kásler, Miklós}, doi = {10.1007/s12253-010-9344-9}, journal-iso = {PATHOL ONCOL RES}, journal = {PATHOLOGY AND ONCOLOGY RESEARCH}, volume = {17}, unique-id = {1695701}, issn = {1219-4956}, abstract = {Our retrospective analysis compared the effectiveness of conventional antracycline-containing protocols (A+) and docetaxel/epirubicine (TE) as primary systemic chemotherapies (PSCT) for inflammatory breast cancer (IBC). Seventy IBC patients received either A + (n = 48) or TE (n = 22) as PSCT. The objective clinical response and clinical benefit rate of treated patients were 54.3% (A+: 54,2% vs. TE: 54,5%; p = 0,28) and 92.8% (A+: 91,7% vs. TE: 95,5%; p = 0,57), respectively. The clinical complete response rate (cCR) was 23.2% (A+: 27,1% vs. TE:4,5%; chi (2) = 4,79; p = 0,03) with 7.14% (A+: 10,4% vs. TE:0%; chi (2) = 2,47; p = 0,12) of pathological complete responses (pCR). The median progression free (PFS)/local progression free (LPFS)/overall survival (OS) was 2.0/5.4/4.0 years, respectively. Patients achieving cCR had a tendency for better survival parameters than patients with less than cCR. Response rates or survival data were not statistically different in the two chemotherapy (CT) treatment groups. The survival was not influenced by the number of CT cycles in either protocols. In this set of patients, the clinical efficacy of the two alternative primary systemic chemotherapies (A + and TE) is equivalent in the treatment of inflammatory breast cancer (IBC), despite of the significant difference in favour of A + noticed in CRs. Six cycles of CT could be enough for patients achieving CR, however sequential pre- and/or postoperative CT with non cross-resistant drugs should be considered for non-responders.}, year = {2011}, eissn = {1532-2807}, pages = {541-550}, orcid-numbers = {Horváth, Zsolt/0000-0002-5376-7737; Torday, László/0000-0002-2911-5499; Polgár, Csaba/0000-0001-7245-0762; Kásler, Miklós/0000-0002-7235-8787} } @article{MTMT:3371928, title = {Búcsúzunk Horti Józseftől (1958-2010)}, url = {https://m2.mtmt.hu/api/publication/3371928}, author = {Eckhardt, Sándor and HORTI, JÓZSEF}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {54}, unique-id = {3371928}, issn = {0025-0244}, keywords = {nekrológ; Orvosok}, year = {2010}, eissn = {2060-0399}, pages = {281} } @article{MTMT:3371914, title = {Búcsúzunk Sugár János professzortól (1922-2010)}, url = {https://m2.mtmt.hu/api/publication/3371914}, author = {Eckhardt, Sándor and SUGÁR, JÁNOS}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {54}, unique-id = {3371914}, issn = {0025-0244}, keywords = {nekrológ; Orvosok}, year = {2010}, eissn = {2060-0399}, pages = {5} } @article{MTMT:1816058, title = {Az emlőrák belgyógyászati onkológiai (gyógyszeres) kezelése [Clinical oncology treatment of breast cancer]}, url = {https://m2.mtmt.hu/api/publication/1816058}, author = {Láng, István and Kahán, Zsuzsanna and Pintér, T and Dank, Magdolna and Boér, Katalin and Pajkos, G and Faluhelyi, Zs and Pikó, B and Eckhardt, Sándor and Horváth, Zsolt}, journal-iso = {ORVOSKÉPZÉS}, journal = {ORVOSKÉPZÉS}, volume = {85}, unique-id = {1816058}, issn = {0030-6037}, year = {2010}, pages = {305-322}, orcid-numbers = {Kahán, Zsuzsanna/0000-0002-5021-8775; Dank, Magdolna/0000-0002-4442-8733; Boér, Katalin/0000-0002-5101-7289; Horváth, Zsolt/0000-0002-5376-7737} } @article{MTMT:1622272, title = {Az emlőrák belgyógyászati onkológiai (gyógyszeres) kezelése}, url = {https://m2.mtmt.hu/api/publication/1622272}, author = {Láng, István and Kahán, Zsuzsanna and Pintér, Tamás and Dank, Magdolna and Boér, Katalin and Pajkos, Gábor and Faluhelyi, Zsolt and Pikó, Béla and Eckhardt, Sándor and Horváth, Zsolt}, doi = {10.1556/MOnkol.54.2010.3.5}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {54}, unique-id = {1622272}, issn = {0025-0244}, year = {2010}, eissn = {2060-0399}, pages = {237-254}, orcid-numbers = {Kahán, Zsuzsanna/0000-0002-5021-8775; Dank, Magdolna/0000-0002-4442-8733; Boér, Katalin/0000-0002-5101-7289; Horváth, Zsolt/0000-0002-5376-7737} } @article{MTMT:3371949, title = {Gondolatok a magyar nép egészségéről}, url = {https://m2.mtmt.hu/api/publication/3371949}, author = {Eckhardt, Sándor}, journal-iso = {EGÉSZSÉGTUDOMÁNY}, journal = {EGÉSZSÉGTUDOMÁNY}, volume = {53}, unique-id = {3371949}, issn = {0013-2268}, abstract = {A szerző az MTA Prevenciós Bizottsága elnökeként tíz év alatt számos népegészségügyi probléma megvitatását szervezte meg. E viták tanulságaként kifejti véleményét a népegészségügyi programok eddig elért eredményeiről és kudarcairól, valamint számba veszi a közeljövő feladatait}, keywords = {PREVENTIO; NÉPEGÉSZSÉGÜGY}, year = {2009}, pages = {7-17} } @article{MTMT:1281160, title = {Epidermal growth factor receptor (EGFR) high gene copy number and activating mutations in lung adenocarcinomas are not consistently accompanied by positivity for EGFR protein by standard immunohistochemistry}, url = {https://m2.mtmt.hu/api/publication/1281160}, author = {Pintér, Ferenc and Pápay, Judit and Almasi, A and Sápi, Zoltán and Z. Szabó, Edit and Kanya, M and Tamasi, A and Jori, B and Varkondi, E and Moldvay, Judit and Szondy, Klára and Kéri, György and Dominici, M and Conte, P and Eckhardt, Sándor and Kopper, László and Schwab, R and Peták, István}, doi = {10.2353/jmoldx.2008.070125}, journal-iso = {J MOL DIAGN}, journal = {JOURNAL OF MOLECULAR DIAGNOSTICS}, volume = {10}, unique-id = {1281160}, issn = {1525-1578}, year = {2008}, eissn = {1943-7811}, pages = {160-168}, orcid-numbers = {Pápay, Judit/0000-0003-2642-2060; Szondy, Klára/0000-0002-3717-3293; Kopper, László/0000-0002-4921-3678; Peták, István/0000-0003-0422-9286} } @article{MTMT:1122596, title = {A Magyar Onkológusok Társaságának XXVII. Jubileumi Kongresszusa}, url = {https://m2.mtmt.hu/api/publication/1122596}, author = {Besznyák, István Endre and Eckhardt, Sándor and Lapis, Károly and Kásler, Miklós and Szűcs, Miklós and Oláh, Edit and Landherr, László and Faluhelyi, Zsolt and Horváth, Zsolt and Rahóty, Pál}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {51}, unique-id = {1122596}, issn = {0025-0244}, year = {2007}, eissn = {2060-0399}, pages = {285-420}, orcid-numbers = {Kásler, Miklós/0000-0002-7235-8787; Horváth, Zsolt/0000-0002-5376-7737} }