@article{MTMT:36102520,
	title = {Flavonoids from the leaves of Monanthotaxis filipes modulate PCSK9 and LDLR},
	url = {https://m2.mtmt.hu/api/publication/36102520},
	author = {Mayeka, James G. and Atilaw, Yoseph and Shadrack, Daniel M. and Sarnyai, Farkas and Csala, Miklós and Németh, Krisztina and Nyandoro, Stephen S. and Tamási, Viola and Erdelyi, Mate and Munissi, Joan J.E.},
	doi = {10.1016/j.sciaf.2025.e02709},
	journal-iso = {SCI AFRICAN},
	journal = {SCIENTIFIC AFRICAN},
	volume = {28},
	unique-id = {36102520},
	issn = {2468-2276},
	year = {2025},
	eissn = {2468-2276},
	orcid-numbers = {Mayeka, James G./0009-0007-2082-6263; Sarnyai, Farkas/0000-0002-5525-5508; Csala, Miklós/0000-0002-3829-4361; Németh, Krisztina/0000-0002-3825-2137; Tamási, Viola/0000-0001-7419-5603; Erdelyi, Mate/0000-0003-0359-5970; Munissi, Joan J.E./0000-0003-1505-6309}
}

@article{MTMT:36102781,
	title = {Dynamically chiral phosphonic acid-type metallo-β-lactamase inhibitors},
	url = {https://m2.mtmt.hu/api/publication/36102781},
	author = {Gulyás, Kinga Virág and Zhou, Liping and Salamonsen, Daniel and Prester, Andreas and Bartels, Kim and Bosman, Robert and Haffke, Paul and Li, Jintian and Tamási, Viola and Deufel, Fritz and Thoma, Johannes and Andersson Rasmussen, Anna and Csala, Miklós and Schroder Leiros, Hanna-Kirsti and Xu, Zhijian and Widersten, Mikael and Rohde, Holger and Schulz, Eike C. and Zhu, Weiliang and Erdélyi, Máté},
	doi = {10.1038/s42004-025-01510-5},
	journal-iso = {COMMUN CHEM},
	journal = {COMMUNICATIONS CHEMISTRY},
	volume = {8},
	unique-id = {36102781},
	issn = {2399-3669},
	abstract = {Antibiotic resistance is a growing global health threat that risks the lives of millions. Among the resistance mechanisms, that mediated by metallo-β-lactamases is of particular concern as these bacterial enzymes dismantle most β-lactam antibiotics, which are our widest applied and cheapest to produce antibiotic agents. So far, no clinically applicable metallo-β-lactamase inhibitors are available. Aiming to adapt to structural variations, we introduce the inhibitor concept: dynamically chiral phosphonic acids. We demonstrate that they are straightforward to synthesize, penetrate bacterial membranes, inhibit the metallo-β-lactamase enzymes NDM-1, VIM-2 and GIM-1, and are non-toxic to human cells. Mimicking the transition state of β-lactam hydrolysis, they target the Zn ions of the metallo-β-lactamase active site. As a unique feature, both of their stereoisomers bind metallo-β-lactamases, which provides them unparalleled adaptability to the structural diversity of these enzymes, and may allow them to hamper bacteria’s ability for resistance development.},
	year = {2025},
	eissn = {2399-3669},
	orcid-numbers = {Prester, Andreas/0000-0003-2738-7682; Tamási, Viola/0000-0001-7419-5603; Deufel, Fritz/0000-0003-4910-3388; Thoma, Johannes/0000-0003-3584-8274; Csala, Miklós/0000-0002-3829-4361; Schroder Leiros, Hanna-Kirsti/0000-0002-2726-6322; Xu, Zhijian/0000-0002-3063-8473; Widersten, Mikael/0000-0002-3203-3793; Rohde, Holger/0000-0001-8587-4433; Schulz, Eike C./0000-0002-1685-8605; Zhu, Weiliang/0000-0001-6699-5299; Erdélyi, Máté/0000-0003-0359-5970}
}

@book{MTMT:36437867,
	title = {Molecular Cell Biology},
	url = {https://m2.mtmt.hu/api/publication/36437867},
	isbn = {9789633316900},
	editor = {Csala, Miklós and Sipeki, Szabolcs},
	publisher = {Semmelweis Kiadó és Multimédia Stúdió},
	unique-id = {36437867},
	year = {2025},
	orcid-numbers = {Csala, Miklós/0000-0002-3829-4361; Sipeki, Szabolcs/0000-0002-9678-6743}
}

@{MTMT:36443126,
	title = {RNA synthesis and its regulation},
	url = {https://m2.mtmt.hu/api/publication/36443126},
	author = {Csala, Miklós},
	booktitle = {Molecular Cell Biology},
	unique-id = {36443126},
	year = {2025},
	pages = {68-93},
	orcid-numbers = {Csala, Miklós/0000-0002-3829-4361}
}

@{MTMT:36443133,
	title = {Molecular biology of viruses},
	url = {https://m2.mtmt.hu/api/publication/36443133},
	author = {Csala, Miklós},
	booktitle = {Molecular Cell Biology},
	unique-id = {36443133},
	year = {2025},
	pages = {150-185},
	orcid-numbers = {Csala, Miklós/0000-0002-3829-4361}
}

@{MTMT:36443144,
	title = {Control of the eukaryotic cell cycle},
	url = {https://m2.mtmt.hu/api/publication/36443144},
	author = {Csala, Miklós},
	booktitle = {Molecular Cell Biology},
	unique-id = {36443144},
	year = {2025},
	pages = {186-198},
	orcid-numbers = {Csala, Miklós/0000-0002-3829-4361}
}

@{MTMT:36443150,
	title = {Apoptosis},
	url = {https://m2.mtmt.hu/api/publication/36443150},
	author = {Csala, Miklós},
	booktitle = {Molecular Cell Biology},
	unique-id = {36443150},
	year = {2025},
	pages = {199-214},
	orcid-numbers = {Csala, Miklós/0000-0002-3829-4361}
}

@{MTMT:36443158,
	title = {Molecular basis of tumor formation},
	url = {https://m2.mtmt.hu/api/publication/36443158},
	author = {Csala, Miklós},
	booktitle = {Molecular Cell Biology},
	unique-id = {36443158},
	year = {2025},
	pages = {221-231},
	orcid-numbers = {Csala, Miklós/0000-0002-3829-4361}
}

@misc{MTMT:36945794,
	title = {Identification of ceramide synthase (CERS) isoenzyme(s) involved in the incorporation of trans fatty acids},
	url = {https://m2.mtmt.hu/api/publication/36945794},
	author = {Palczert, Zoltán and Blanka, Tóth and Sarnyai, Farkas and Emese, Domokos and Anar, Batzorig and Zsófia, Gonda and Mária, Katalin Geringen and Csala, Miklós and Tamási, Viola},
	unique-id = {36945794},
	year = {2025},
	orcid-numbers = {Sarnyai, Farkas/0000-0002-5525-5508; Csala, Miklós/0000-0002-3829-4361; Tamási, Viola/0000-0001-7419-5603}
}

@article{MTMT:34473748,
	title = {Allele-specific effect of various dietary fatty acids and ETS1 transcription factor on SCD1 expression},
	url = {https://m2.mtmt.hu/api/publication/34473748},
	author = {Tibori, Kinga and Zámbó, Veronika and Orosz, Gabriella and Szelényi, Péter and Sarnyai, Farkas and Tamási, Viola and Rónai, Zsolt and Csala, Miklós and Kereszturi, Éva},
	doi = {10.1038/s41598-023-50700-5},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {14},
	unique-id = {34473748},
	abstract = {Overnutrition and genetic predisposition are major risk factors for various metabolic disorders. Stearoyl-CoA desaturase-1 (SCD1) plays a key role in these conditions by synthesizing unsaturated fatty acids (FAs), thereby promoting fat storage and alleviating lipotoxicity. Expression of SCD1 is influenced by various saturated and cis-unsaturated FAs, but the possible role of dietary trans FAs (TFAs) and SCD1 promoter polymorphisms in its regulations has not been addressed. Therefore, we aimed to investigate the impact of the two main TFAs, vaccenate and elaidate, and four common promoter polymorphisms (rs1054411, rs670213, rs2275657, rs2275656) on SCD1 expression in HEK293T and HepG2 cell cultures using luciferase reporter assay, qPCR and immunoblotting. We found that SCD1 protein and mRNA levels as well as SCD1 promoter activity are markedly elevated by elaidate, but not altered by vaccenate. The promoter polymorphisms did not affect the basal transcriptional activity of SCD1 . However, the minor allele of rs1054411 increased SCD1 expression in the presence of various FAs. Moreover, this variant was predicted in silico and verified in vitro to reduce the binding of ETS1 transcription factor to SCD1 promoter. Although we could not confirm an association with type 2 diabetes mellitus, the FA-dependent and ETS1-mediated effect of rs1054411 polymorphism deserves further investigation as it may modulate the development of lipid metabolism-related conditions.},
	year = {2024},
	eissn = {2045-2322},
	orcid-numbers = {Tibori, Kinga/0000-0002-6808-4015; Orosz, Gabriella/0000-0002-2030-287X; Sarnyai, Farkas/0000-0002-5525-5508; Tamási, Viola/0000-0001-7419-5603; Rónai, Zsolt/0000-0002-0909-7932; Csala, Miklós/0000-0002-3829-4361}
}