TY - JOUR AU - Kállay-Menyhárd, Alfréd AU - Renkeczné Tátraaljai, Dóra AU - Pukánszky, Béla Jr. AU - Nagyné László, Krisztina AU - Bulátkó, Anna AU - Nagyné Albert, Emőke AU - Tegze, Borbála Ágnes AU - Márton, Péter AU - Hórvölgyi, Zoltán AU - Gyarmati, Benjámin Sándor AU - Szilágyi, András Ferenc AU - Hessz, Dóra AU - Kubinyi, Miklós AU - Kállay, Mihály TI - Kutatómunka a Fizikai Kémia és Anyagtudományi Tanszéken JF - MAGYAR KÉMIKUSOK LAPJA J2 - MAGY KEM LAP VL - 78 PY - 2023 IS - 12 SP - 370 EP - 375 PG - 6 SN - 0025-0163 UR - https://m2.mtmt.hu/api/publication/34452555 ID - 34452555 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Stankovits, József Gergely AU - Ábrahám, Ágnes AU - Kiss, Éva AU - Varga, Zoltán AU - Misra, Anil AU - Szilágyi, András Ferenc AU - Gyarmati, Benjámin Sándor TI - The interaction between mucin and poly(amino acid)s with controlled cationic group content in bulk phase and in thin layers JF - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES J2 - INT J BIOL MACROMOL VL - 253 PY - 2023 IS - 5 PG - 12 SN - 0141-8130 DO - 10.1016/j.ijbiomac.2023.126826 UR - https://m2.mtmt.hu/api/publication/34140818 ID - 34140818 N1 - Funding Agency and Grant Number: National Research, Development and Innovation (NRDI) Fund [TKP-9-8/PALY-2021]; NRDI Office [TKP2021-EGA]; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences [FK 138029]; NKP- 22-5 New National Excellence Program of the Ministry for Innovation and Technology from the source of the NRDI Fund; National Talent Programme of Hungary [NKP-22-5-BME-297]; Lenduelet (Momentum) Programme of the Hungarian Academy of Sciences; National Research, Development and Innovation Fund of Hungary [LENDULET_2021-28]; European Union [2018-1.2.1-NKP-2018-00005]; State of Hungary [2018-1.2.1- NKP]; European Regional Development Fund [VEKOP- 2.3.3-15-2017-00020]; NanoMed project; [H2020-MSCA-RISE-2016-734641] Funding text: Project no. TKP-9-8/PALY-2021 has been implemented with the support provided by the Ministry of Culture and Innovation of Hungary from the National Research, Development and Innovation (NRDI) Fund, financed under the TKP2021-EGA funding scheme. Further support was provided by the NRDI Office via grant FK 138029. B. Gyarmati and Z. Varga acknowledge the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences. The work was also supported by the & Uacute;NKP- 22-5 New National Excellence Program (& Uacute;NKP-22-5-BME-297) of the Ministry for Innovation and Technology from the source of the NRDI Fund. G. Stankovits is grateful for the scholarship of the National Talent Programme of Hungary. The work was supported by the Lenduelet (Momentum) Programme of the Hungarian Academy of Sciences (Grant ID: LENDULET_2021-28) . Project no. 2018-1.2.1-NKP-2018-00005 has been implemented with support from the National Research, Development and Innovation Fund of Hungary, financed under the 2018-1.2.1- NKP funding scheme. These studies were supported by a grant (VEKOP- 2.3.3-15-2017-00020) from the European Union and the State of Hungary, co -financed by the European Regional Development Fund. The research was also funded by the H2020-MSCA-RISE-2016-734641 NanoMed project. The authors thank David Kun for his assistance with statistical analysis. Part number: 5 AB - The type and concentration of charged groups in polymers have a key role in mucoadhesive interactions. A series of cationic poly(amino acid)s with different charge densities was designed to unravel the correlation between chemical structure and mucin-polymer interactions. Colloidal interactions between the mucin protein and synthetic polyaspartamides were tested by dynamic light scattering, zeta potential measurements and turbidimetric titration as a function of polymer-to-mucin mass ratio. The mucoadhesive interactions displayed a strongly non -linear change with polymer composition. The attractive interactions between mucin and the polyaspartamides with at least 50 % cationic groups caused increased light scattering of dispersions due to the aggregation of mucin particles upon their charge reversal. Interactions were further analysed in a thin mucin layer to model life-like situations using a quartz crystal microbalance (QCM) in flow mode. Results pointed out that the fully cationic polyaspartamide is not necessarily superior to derivatives with lower cationic group content. The maximum of adsorbed mass of polymers on mucin was experienced at medium cationic group contents. This emphasizes the relevance of cationic polyaspartamides as mucoadhesive excipients due to their multiple functionalities and the possibility of fine-tuning their interactions with mucin via straightforward chemical steps. LA - English DB - MTMT ER - TY - JOUR AU - Szilágyi, Barnabás Áron AU - Gyarmati, Benjámin Sándor AU - L. Kiss, Eszter AU - Budai-Szűcs, Mária AU - Misra, Anil AU - Csányi, Erzsébet AU - Nagyné László, Krisztina AU - Szilágyi, András Ferenc TI - In situ gelation of thiolated poly(aspartic acid) derivatives through oxidant-free disulfide formation for ophthalmic drug delivery JF - COLLOIDS AND SURFACES B: BIOINTERFACES J2 - COLLOID SURFACE B VL - 225 PY - 2023 PG - 10 SN - 0927-7765 DO - 10.1016/j.colsurfb.2023.113254 UR - https://m2.mtmt.hu/api/publication/33734502 ID - 33734502 N1 - Department of Physical Chemistry and Materials Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, H-1111, Hungary Institute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, Eötvös u. 6, Szeged, H-6720, Hungary Pharmidex Pharmaceutical Services, Office 3.05, 1 King Street, London, EC2V 8AU, United Kingdom CODEN: CSBBE Correspondence Address: Szilágyi, A.; Department of Physical Chemistry and Materials Science, Műegyetem rkp. 3, Hungary; email: szilagyi.andras@vbk.bme.hu LA - English DB - MTMT ER - TY - JOUR AU - Al-Lami, Munaf AU - Szilágyi, András Ferenc AU - Havasi, Dávid AU - Mika, László Tamás TI - 1,4-Pentanediol: Vapor Pressure, Density, Viscosity, Refractive Index, and Its Isobaric Vapor–Liquid Equilibrium with 2-Methyltetrahydrofurane JF - JOURNAL OF CHEMICAL AND ENGINEERING DATA J2 - J CHEM ENG DATA VL - 67 PY - 2022 IS - 6 SP - 1450 EP - 1459 PG - 10 SN - 0021-9568 DO - 10.1021/acs.jced.2c00049 UR - https://m2.mtmt.hu/api/publication/32896153 ID - 32896153 N1 - Funding Agency and Grant Number: National Research, Development and Innovation Office-NKFIH [KH 129508, 2019-1.3.1-KK-2019-00004]; National Research, Development and Innovation Fund of Hungary [2019-1.3.1-KK] Funding text: The authors thank Mr. Laszlo Monori, M.Sc. in chemical engineering, for synthesis and for performing vapor pressure measurements of 1,4-pentanediol. This work was funded by the National Research, Development and Innovation Office-NKFIH (KH 129508). Project no. 2019-1.3.1-KK-2019-00004 has been implemented with the support provided by the National Research, Development and Innovation Fund of Hungary, financed under the 2019-1.3.1-KK funding scheme. LA - English DB - MTMT ER - TY - JOUR AU - Mammadova, Aysel AU - Gyarmati, Benjámin Sándor AU - Sárdi, Kitti AU - Paudics, Adrien AU - Varga, Zoltán AU - Szilágyi, András Ferenc TI - Thiolated cationic poly(aspartamides) with side group dependent gelation properties for the delivery of anionic polyelectrolytes JF - JOURNAL OF MATERIALS CHEMISTRY B J2 - J MATER CHEM B VL - 10 PY - 2022 IS - 31 SP - 5946 EP - 5957 PG - 12 SN - 2050-750X DO - 10.1039/D2TB00674J UR - https://m2.mtmt.hu/api/publication/32895627 ID - 32895627 N1 - Funding Agency and Grant Number: Ministry for Innovation and Technology of Hungary from the National Research, Development and Innovation (NRDI) Fund [TKP2021-EGA-02]; NRDI Office [FK 125074, FK 138029]; Hungarian Academy of Sciences; New National Excellence Program of the Ministry for Innovation and Technology from the source of the NRDI Fund [uNKP-21-5]; Stipendium Hungaricum Funding text: We would like to thank Dr Katalin Kopecsko and Erika Grossmann from the Faculty of Civil Engineering, Budapest University of Technology and Economics (BME), for their help in particle size and zeta potential measurements. The help of Robert Kovacs and Peter Gordon (Faculty of Electrical Engineering and Informatics, BME) in SEM measurements is highly appreciated. The research reported in this paper is part of project no. TKP2021-EGA-02, implemented with the support provided by the Ministry for Innovation and Technology of Hungary from the National Research, Development and Innovation (NRDI) Fund, financed under the TKP2021 funding scheme. Further support was provided by the NRDI Office via grants FK 125074 and FK 138029. B. Gyarmati acknowledges the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences. The work was also supported by the uNKP-21-5 New National Excellence Program of the Ministry for Innovation and Technology from the source of the NRDI Fund. A. Mammadova is grateful for the scholarship of Stipendium Hungaricum. AB - In situ gellable polymers have potential applications as injectable formulations in drug delivery and regenerative medicine. Herein, thiolated cationic polyaspartamides were synthesised via two different approaches to correlate the side group structure with gelation properties, gel strength and drug release kinetics. Cysteamine (CEA) was used as a thiolating agent to prepare thiolated cationic polyaspartamide groups with short thiolated side groups. As a new pathway, thiolactone chemistry was integrated with cationic modification of polyaspartamides to prepare thiolated derivatives with longer, flexible side groups using N-acetyl-DL-homocysteine (NAH) thiolactone. Both types of thiolated polyaspartamides could be converted into stiff hydrogels under mild reaction conditions through oxidation-induced intermolecular disulfide formation. We confirmed that the longer side groups largely accelerated gelation and the stiffness of the resultant hydrogels was higher than that of the CEA-modified counterparts. Both the gelation time and stiffness could be adjusted by the degree of thiolation. Poly(aspartic acid) (PASP) derivatives with a controlled concentration of anionic groups were entrapped in the hydrogels during the in situ gelation. Based on the possible electrostatic interaction between the linear anionic polyelectrolytes and the cationic polymer network, we hypothesized that the release of the encapsulated material is controlled by the charge density. In accordance, fully anionic PASP was entrapped completely in the hydrogels, whereas a reduction in the number of anionic groups caused the partial release of PASP derivatives. NAH- and CEA- modified cationic polyaspartamide hydrogels showed distinct release rates, indicating the interplay between cationic and thiol functionalities in release kinetics. LA - English DB - MTMT ER - TY - JOUR AU - Gyarmati, Benjámin Sándor AU - Stankovits, József Gergely AU - Szilágyi, Barnabás Áron AU - Galata, Dorián László AU - Gordon, Péter AU - Szilágyi, András Ferenc TI - A robust mucin-containing poly(vinyl alcohol) hydrogel model for the in vitro characterization of mucoadhesion of solid dosage forms JF - COLLOIDS AND SURFACES B: BIOINTERFACES J2 - COLLOID SURFACE B VL - 213 PY - 2022 SN - 0927-7765 DO - 10.1016/j.colsurfb.2022.112406 UR - https://m2.mtmt.hu/api/publication/32765035 ID - 32765035 N1 - Department of Physical Chemistry and Materials Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, H-1111, Hungary Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, H-1111, Hungary Department of Electronics Technology, Faculty of Electrical Engineering and Informatics, Budapest University of Technology and Economics, Műegyetem rkp. 3., Budapest, H-111, Hungary Export Date: 6 April 2022 CODEN: CSBBE Correspondence Address: Gyarmati, B.; Department of Physical Chemistry and Materials Science, Műegyetem rkp. 3, Hungary; email: gyarmati.benjamin@vbk.bme.hu Funding details: FK 125074, FK 138029 Funding details: Magyar Tudományos Akadémia, MTA Funding details: Innovációs és Technológiai Minisztérium Funding details: National Research, Development and Innovation Office Funding text 1: The research reported in this paper is part of project no. TKP2021-EGA-02 , implemented with the support provided by the Ministry for Innovation and Technology of Hungary from the National Research , Development and Innovation (NRDI) Fund , financed under the TKP2021 funding scheme. We would like to thank Dr. János Móczó for his help in particle size measurements. Further support was provided by the NRDI Office via grant FK 125074 and FK 138029 . B. Gyarmati acknowledges the János Bolyai Research Scholarship of the Hungarian Academy of Sciences . The work was also supported by the ÚNKP-21–5 New National Excellence Program of the Ministry for Innovation and Technology from the source of the NRDI Fund . LA - English DB - MTMT ER - TY - JOUR AU - Gyarmati, Benjámin Sándor AU - Dargó, Gergő AU - Szilágyi, Barnabás Áron AU - Vincze, Anna AU - Facskó, Réka AU - Budai-Szűcs, Mária AU - L. Kiss, Eszter AU - Szente, Lajos AU - Szilágyi, András Ferenc AU - Balogh, György Tibor TI - Synthesis, complex formation and corneal permeation of cyclodextrin-modified, thiolated poly(aspartic acid) as self-gelling formulation of dexamethasone JF - EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS J2 - EUR J PHARM BIOPHARM VL - 174 PY - 2022 SP - 1 EP - 9 PG - 9 SN - 0939-6411 DO - 10.1016/j.ejpb.2022.03.008 UR - https://m2.mtmt.hu/api/publication/32759014 ID - 32759014 N1 - Department of Physical Chemistry and Materials Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., Budapest, H-1111, Hungary Department of Chemical and Process Engineering, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rakpart 3., Budapest, H-1111, Hungary Institute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, Eötvös utca 6., Szeged, H-6720, Hungary CycloLab Cyclodextrin R. and D. Laboratory, Ltd, H-1070 Budapest, Illatos út 7, Hungary Institute of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös utca 6., Szeged, H-6720, Hungary Export Date: 5 May 2022 CODEN: EJPBE Correspondence Address: Balogh, G.T.; Department of Chemical and Process Engineering, Műegyetem rakpart 3., Hungary; email: balogh.gyorgy@vbk.bme.hu Correspondence Address: Szilagyi, A.; Department of Physical Chemistry and Materials Science, Műegyetem rkp. 3., Hungary; email: szilagyi.andras@vkb.bme.hu LA - English DB - MTMT ER - TY - JOUR AU - Bakos, Vince AU - Gyarmati, Benjámin Sándor AU - Csizmadia, Péter AU - Till, Sára AU - Vachoud, L. AU - Göde, P. Nagy AU - Tardy, Gábor Márk AU - Szilágyi, András Ferenc AU - Jobbágy, A. AU - Wisniewski, C. TI - Viscous and filamentous bulking in activated sludge: Rheological and hydrodynamic modelling based on experimental data JF - WATER RESEARCH J2 - WATER RES VL - 214 PY - 2022 PG - 10 SN - 0043-1354 DO - 10.1016/j.watres.2022.118155 UR - https://m2.mtmt.hu/api/publication/32653430 ID - 32653430 N1 - Department of Applied Biotechnology and Food Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., Budapest, H-1111, Hungary Department of Chemical Engineering, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom Department of Physical Chemistry and Materials Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., Budapest, H-1111, Hungary Department of Hydrodynamic Systems, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Műegyetem rkp. 3., Budapest, H-1111, Hungary Qualisud, Université de Montpellier, CIRAD, Institut Agro, Avignon Université, Université de La Réunion, Montpellier, France DMRV Pte. Ltd., Kodály Zoltán út 3., Vác, H-2600, Hungary Export Date: 6 April 2022 CODEN: WATRA Correspondence Address: Bakos, V.; Department of Applied Biotechnology and Food Science, Műegyetem rkp. 3., Hungary; email: bakos.vince@vbk.bme.hu Funding details: Budapesti Műszaki és Gazdaságtudományi Egyetem, BME Funding details: Providence Health Care, PHC, 34474QA Funding details: Magyar Tudományos Akadémia, MTA, ÚNKP-19-4-BME-421, ÚNKP-20-5-BME-156 Funding details: Emberi Eroforrások Minisztériuma, EMMI Funding details: Campus France Funding details: Université de Montpellier, UM Funding details: Nemzeti Kutatási Fejlesztési és Innovációs Hivatal, NKFIH, TÉT-14-FR-1-2015-0033 Funding text 1: The cross-border cooperation was supported both by Hungarian National Research, Development and Innovation Office (T?T-14-FR-1-2015-0033) and Campus France (PHC Balaton No.34474QA). Professional contribution of Michele Delalonde and the technical help of Emilie Ruiz (UMR QualiSud, University of Montpellier) is highly acknowledged. Additional support of the Higher Education Excellence Program of the Ministry of Human Capacities (EMMI) within the frame of both Biotechnology and Water Science and Disaster Prevention research areas of Budapest University of Technology and Economics (BME FIKP-BIO and FIKP-VIZ) is also highly appreciated. Authors acknowledge the J?nos Bolyai Research Scholarship of the Hungarian Academy of Sciences and the ?NKP-19-4-BME-421, ?NKP-20-5-BME-156, ?NKP-21-5-BME New National Excellence Program of the Ministry of Human Capacities. Funding text 2: The cross-border cooperation was supported both by Hungarian National Research, Development and Innovation Office (TÉT-14-FR-1-2015-0033) and Campus France (PHC Balaton No.34474QA). Professional contribution of Michele Delalonde and the technical help of Emilie Ruiz (UMR QualiSud, University of Montpellier) is highly acknowledged. Additional support of the Higher Education Excellence Program of the Ministry of Human Capacities (EMMI) within the frame of both Biotechnology and Water Science and Disaster Prevention research areas of Budapest University of Technology and Economics (BME FIKP-BIO and FIKP-VIZ) is also highly appreciated. Authors acknowledge the János Bolyai Research Scholarship of the Hungarian Academy of Sciences and the ÚNKP-19-4-BME-421, ÚNKP-20-5-BME-156, ÚNKP-21-5-BME New National Excellence Program of the Ministry of Human Capacities. AB - Although achieving good activated sludge settleability is a key requirement for meeting effluent quality criteria, wastewater treatment plants often face undesired floc structure changes. Filamentous bulking has widely been studied, however, viscous sludge formation much less investigated so far. Our main goal was to find relationship between sludge floc structure and related rheological properties, moreover, to estimate pressure loss in pipe networks through hydrodynamic modelling of the non-Newtonian flows in case of well settling (ideal-like), viscous and filamentous sludge. Severe viscous and filamentous kinds of bulking were generated separately in continuous-flow lab-scale systems initially seeded with the same reference (ideal-like) biomass and the entire evolution of viscous and filamentous bulking was monitored. The results suggested correlation between the rheological properties and the floc structure transformations, and showed the most appropriate fit for the Herschel-Bulkley model (vs. Power-law and Bingham). Validated computational fluid dynamics studies estimated the pipe pressure loss in a wide Reynolds number range for the initial well settling (reference) and the final viscous and filamentous sludge as well. A practical standard modelling protocol was developed for improving energy efficiency of sludge pumping in different floc structure scenarios. LA - English DB - MTMT ER - TY - JOUR AU - Nagy, Flóra AU - Bell, Evelin AU - Jipa, Monica AU - Hornyánszky, Gábor AU - Szilágyi, András Ferenc AU - Nagyné László, Krisztina AU - Katona, Gábor AU - Paizs, Csaba AU - Poppe, László AU - Balogh Weiser, Diána TI - Cross-Linked Enzyme-Adhered Nanoparticles (CLEANs) for Continuous-Flow Bioproduction JF - CHEMSUSCHEM J2 - CHEMSUSCHEM VL - 15 PY - 2022 IS - 2 PG - 10 SN - 1864-5631 DO - 10.1002/cssc.202102284 UR - https://m2.mtmt.hu/api/publication/32515084 ID - 32515084 N1 - Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, 1111, Hungary Biocatalysis and Biotransformation Research Center, Babeş-Bolyai University of Cluj-Napoca, Arany János str. 11, Cluj-Napoca, 400028, Romania Department of Physical Chemistry and Materials Science, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, 1111, Hungary SynBiocat LLC, Szilasliget u 3, Budapest, 1072, Hungary Export Date: 5 April 2022 CODEN: CHEMI Correspondence Address: Poppe, L.; Department of Organic Chemistry and Technology, Műegyetem rkp. 3, Hungary; email: poppe.laszlo@vbk.bme.hu Correspondence Address: Balogh-Weiser, D.; Department of Organic Chemistry and Technology, Műegyetem rkp. 3, Hungary; email: balogh.weiser.diana@vbk.bme.hu Funding details: 103413, P37_273 Funding details: 131467 Funding details: Budapesti Műszaki és Gazdaságtudományi Egyetem, BME Funding details: Magyar Tudományos Akadémia, MTA, BO/00175/21, ÚNKP‐21‐5‐BME‐386 Funding details: Emberi Eroforrások Minisztériuma, EMMI Funding text 1: This work was supported by the Higher Education Excellence Program of the Ministry of Human Capacities (Budapest, Hungary) in the frame of Biotechnology research area of Budapest University of Technology and Economics (TKP2020 IES, Grant No. BME‐IE‐BIO). D.B.W. thanks support form NKFIH‐PD‐19 (ID: 131467) and acknowledges the János Bolyai Research Scholarship of the Hungarian Academy of Sciences (BO/00175/21) and the ÚNKP‐21‐5 (ÚNKP‐21‐5‐BME‐386) New National Excellence Program of the Ministry of Human Capacities. C.P., G.K., and L.P. thank the support of NEMSyB, ID P37_273, Cod MySMIS 103413 [funded by Ministry of Education and Research, Bucharest, Romania and European Regional Development Fund, Competitiveness Operational Program 2014–2020 (POC), Priority axis 1, Action 1.1]. D.B.W. was also financed by CELSA (KU Leuven‐BME: ConSolid, 2020). AB - Nanostructured but micro-sized biocatalysts were created by bottom-up technology using multi-functionalized silica nanoparticles (NPs) as nano-sized building blocks to form cross-linked enzyme-adhered nanoparticles (CLEANs) as robust micro-sized particles with beneficial internal structure and good mechanical properties. Systematic surface modification of NPs with a grafting mixture consisting of organosilanes with reactive (aminopropyl) and inert (e. g., vinyl, propyl, phenyl, or octyl) functions resulted in functional NPs enabling cross-linking agents, such as glutardialdehyde or bisepoxides (glycerol diglycidyl ether, neopentylglycol diglycidyl ether, and poly(propylene glycol) diglycidyl ether), to bind and cross-link enzymes covalently and to form macroporous microparticles. These CLEANs were able to diminish several weaknesses of traditional cross-linked enzyme aggregates as biocatalysts, such as poor mechanical resistance, difficult recovery, and storage, strengthening their use for packed-bed enzyme reactors. Lipase B from Candida antarctica (CaLB) was selected as model enzyme for development of robust CLEANs, which were successfully tested for various industrially relevant applications including a kinetic resolution of a racemic alcohol and the production of various natural fragrance compounds under continuous-flow conditions. LA - English DB - MTMT ER - TY - JOUR AU - Koplányi, Gábor AU - Bell, Evelin AU - Molnár, Zsófia Klára AU - Tóth, Gergő Dániel AU - Józó, Muriel AU - Szilágyi, András Ferenc AU - Ender, Ferenc AU - Pukánszky, Béla AU - Vértessy, Beáta (Grolmuszné) AU - Poppe, László AU - Balogh Weiser, Diána TI - Entrapment of Phenylalanine Ammonia-Lyase in Nanofibrous Polylactic Acid Matrices by Emulsion Electrospinning JF - CATALYSTS J2 - CATALYSTS VL - 11 PY - 2021 IS - 10 PG - 14 SN - 2073-4344 DO - 10.3390/catal11101149 UR - https://m2.mtmt.hu/api/publication/32242806 ID - 32242806 N1 - Export Date: 26 October 2021 LA - English DB - MTMT ER -