TY - JOUR AU - Hadjadj, Rachid AU - Csizmadia, Imre Gyula AU - Qasim, Hadeer Waleed AU - Aljaberi , Dalal Karad Thbayh AU - Viskolcz, Béla AU - Fiser, Béla TI - Monoethanolamine assisted CO2 hydrogenation to methanol – A computational study JF - MOLECULAR CATALYSIS J2 - MOL CATAL VL - 559 PY - 2024 SN - 2468-8231 DO - 10.1016/j.mcat.2024.114091 UR - https://m2.mtmt.hu/api/publication/34829600 ID - 34829600 LA - English DB - MTMT ER - TY - JOUR AU - Hegedüs, Balázs AU - Palotás, Árpád Bence AU - Muránszky, Gábor AU - Dobó, Zsolt TI - Investigation of gasoline-like transportation fuel obtained by plastic waste pyrolysis and distillation JF - JOURNAL OF CLEANER PRODUCTION J2 - J CLEAN PROD VL - 447 PY - 2024 SN - 0959-6526 DO - 10.1016/j.jclepro.2024.141500 UR - https://m2.mtmt.hu/api/publication/34824897 ID - 34824897 LA - English DB - MTMT ER - TY - CONF AU - Konyhás, Vivien AU - Polyákné Kovács, Annamária TI - Optimization of Continuous Soft Polyurethane Foam Production Considering Sustainability Parameters T2 - Abstract Book of 4th International Artificial Intelligence and Data Science Congress ICADA 2024 SN - 9786256530904 PY - 2024 SP - 41 EP - 41 PG - 1 UR - https://m2.mtmt.hu/api/publication/34764698 ID - 34764698 LA - English DB - MTMT ER - TY - JOUR AU - Csomos, Attila AU - Madarász, Miklós AU - Turczel, Gábor AU - Cseri, Levente AU - Katona, Gergely AU - Rózsa J., Balázs AU - Kovács, Ervin AU - Mucsi, Zoltán TI - A Molecular Hybrid of the GFP Chromophore and 2,2′-Bipyridine: An Accessible Sensor for Zn2+ Detection with Fluorescence Microscopy JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 25 PY - 2024 IS - 6 PG - 14 SN - 1661-6596 DO - 10.3390/ijms25063504 UR - https://m2.mtmt.hu/api/publication/34748236 ID - 34748236 N1 - Department of Chemistry, Femtonics Ltd, Tűzoltó utca 59, Budapest, H-1094, Hungary Hevesy György PhD School of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, Budapest, H-1117, Hungary BrainVisionCenter, Liliom utca 43, Budapest, H-1094, Hungary NMR Research Laboratory, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok körútja 2, Budapest, H-1117, Hungary Department of Organic Chemistry & Technology, Budapest University of Technology & Economics, 3. Muegyetem rakpart, Budapest, H-1111, Hungary Two-Photon Measurement Technology Research Group, Pázmány Péter Catholic University, Práter utca 50/a, Budapest, H-1083, Hungary Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Szigony utca 43, Budapest, H-1083, Hungary Polymer Chemistry and Physics Research Group, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok körútja 2, Budapest, H-1117, Hungary Faculty of Materials and Chemical Sciences, University of Miskolc, Miskolc, H-3515, Hungary Export Date: 12 April 2024 Correspondence Address: Rózsa, B.; BrainVisionCenter, Liliom utca 43, Hungary; email: rozsabal@koki.hu Correspondence Address: Kovács, E.; Two-Photon Measurement Technology Research Group, Práter utca 50/a, Hungary; email: kovacs.ervin@ttk.hu AB - The few commercially available chemosensors and published probes for in vitro Zn2+ detection in two-photon microscopy are compromised by their flawed spectroscopic properties, causing issues in selectivity or challenging multistep syntheses. Herein, we present the development of an effective small molecular GFP chromophore-based fluorescent chemosensor with a 2,2′-bipyridine chelator moiety (GFZnP BIPY) for Zn2+ detection that has straightforward synthesis and uncompromised properties. Detailed experimental characterizations of the free and the zinc-bound compounds within the physiologically relevant pH range are presented. Excellent photophysical characteristics are reported, including a 53-fold fluorescence enhancement with excitation and emission maxima at 422 nm and 492 nm, respectively. A high two-photon cross section of 3.0 GM at 840 nm as well as excellent metal ion selectivity are reported. In vitro experiments on HEK 293 cell culture were carried out using two-photon microscopy to demonstrate the applicability of the novel sensor for zinc bioimaging. LA - English DB - MTMT ER - TY - JOUR AU - Tóth Ugyonka, Helga AU - Hantal, György AU - Szőri, Milán AU - Jedlovszky, Pál TI - Computer Simulation Insights into the Chemical Origins of Life: Can HCN Enrichment on Interstellar Amorphous Ice Be a Starting Point? JF - ACS EARTH AND SPACE CHEMISTRY J2 - ACS EARTH SPACE CHEM VL - 8 PY - 2024 IS - 3 SP - 520 EP - 532 PG - 13 SN - 2472-3452 DO - 10.1021/acsearthspacechem.3c00299 UR - https://m2.mtmt.hu/api/publication/34743348 ID - 34743348 N1 - Export Date: 27 March 2024 Correspondence Address: Szőri, M.; Institute of Chemistry, Egyetemváros A/2, Hungary; email: milan.szori@uni-miskolc.hu Correspondence Address: Jedlovszky, P.; Department of Chemistry, Leányka utca 12, Hungary; email: jedlovszky.pal@uni-eszterhazy.hu LA - English DB - MTMT ER - TY - JOUR AU - Csomos, Attila AU - Madarász, Miklós AU - Turczel, Gábor AU - Cseri, Levente AU - Bodor, Andrea AU - Anett, Matuscsák AU - Katona, Gergely AU - Kovács, Ervin AU - Rózsa J., Balázs AU - Mucsi, Zoltán TI - A GFP inspired 8-methoxyquinoline-derived fluorescent molecular sensor for the detection of Zn2+ by two-photon microscopy JF - CHEMISTRY-A EUROPEAN JOURNAL J2 - CHEM-EUR J PY - 2024 SN - 0947-6539 DO - 10.1002/chem.202400009 UR - https://m2.mtmt.hu/api/publication/34724516 ID - 34724516 AB - An effective, GFP-inspired fluorescent Zn2+ sensor is developed for two-photon microscopy and related biological application that featured an 8-methoxyquinoline moiety. Excellent photophysical characteristics including a 37-fold fluorescence enhancement with excitation and emission maxima at 440 nm and 505 nm, respectively, as well as a high two-photon cross-section of 73 GM at 880 nm are reported. Based on the experimental data, the relationship between the structure and properties was elucidated and explained backed up by DFT calculations, particularly to the observed PeT phenomenon for the turn-on process. Biological validation and detailed experimental and theoretical characterization of the free and the zinc-bound compounds are presented. LA - English DB - MTMT ER - TY - JOUR AU - Reizer, Edina AU - Tokaji, György Marcell AU - Palusiak, Marcin AU - Viskolcz, Béla AU - Fiser, Béla TI - The first step of polycyclic aromatic hydrocarbon growth – A case study of hydrogen abstractions by •H, •OH, and •CH3 radical JF - COMPUTATIONAL AND THEORETICAL CHEMISTRY J2 - COMPUT THEOR CHEM VL - 1234 PY - 2024 PG - 7 SN - 2210-271X DO - 10.1016/j.comptc.2024.114530 UR - https://m2.mtmt.hu/api/publication/34717280 ID - 34717280 LA - English DB - MTMT ER - TY - JOUR AU - Dobó, Máté AU - Dombi, Gergely AU - Köteles, István AU - Fiser, Béla AU - Kis, Csenge AU - Szabó, Zoltán-István AU - Tóth, Gergő TI - Simultaneous Determination of Enantiomeric Purity and Organic Impurities of Dexketoprofen Using Reversed-Phase Liquid Chromatography—Enhancing Enantioselectivity through Hysteretic Behavior and Temperature-Dependent Enantiomer Elution Order Reversal on Polysaccharide Chiral Stationary Phases JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 25 PY - 2024 IS - 5 PG - 15 SN - 1661-6596 DO - 10.3390/ijms25052697 UR - https://m2.mtmt.hu/api/publication/34688029 ID - 34688029 N1 - Export Date: 12 April 2024 Correspondence Address: Tóth, G.; Department of Pharmaceutical Chemistry, Hogyes 9, Hungary; email: toth.gergo@semmelweis.hu AB - A reversed-phase high-performance liquid chromatographic (HPLC) method was developed for the simultaneous determination of the potential impurities of dexketoprofen, including the distomer R-ketoprofen. After screening the separation capability of four polysaccharide columns (Lux Amylose-1, Lux Amylose-2, Lux Cellulose-1 and Lux Cellulose-2) in polar organic and in reversed-phase modes, appropriate enantioseparation was observed only on the Lux Amylose-2 column in an acidified acetonitrile/water mixture. A detailed investigation of the mobile phase composition and temperature for enantio- and chemoselectivity showed many unexpected observations. It was observed that both the resolution and the enantiomer elution order can be fine-tuned by varying the temperature and mobile phase composition. Moreover, hysteresis of the retention times and enantioselectivity was also observed in reversed-phase mode using methanol/water mixtures on amylose-type columns. This could indicate that the three-dimensional structure of the amylose column can change by transitioning from a polar organic to a reversed-phase mode, which affects the enantioseparation process. Temperature-dependent enantiomer elution order and rare enthalpic/entropic controlled enantioseparation in the operative temperature range were also observed in reversed-phase mode. To find the best methodological conditions for the determination of dexketoprofen impurities, a full factorial optimization design was performed. Using the optimized parameters (Lux Amylose-2 column with water/acetonitrile/acetic acid 50/50/0.1 (v/v/v) at a 1 mL/min flow rate at 20 °C), baseline separations were achieved between all compounds within 15 min. Our newly developed HPLC method was validated according to the current guidelines, and its application was tested on commercially available pharmaceutical formulations. According to the authors’ knowledge, this is the first study to report hysteretic behavior on polysaccharide columns in reversed-phase mode. LA - English DB - MTMT ER - TY - JOUR AU - Hatvani-Nagy, Alpár Ferencz AU - Hajdu, Viktória AU - Ilosvai, Mária Ágnes AU - Muránszky, Gábor AU - Sikora, Emőke AU - Kristály, Ferenc AU - Daróczi, Lajos AU - Viskolcz, Béla AU - Fiser, Béla AU - Vanyorek, László TI - Bentonite as eco-friendly natural mineral support for Pd/CoFe2O4 catalyst applied in toluene diamine synthesis JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 14 PY - 2024 IS - 1 PG - 9 SN - 2045-2322 DO - 10.1038/s41598-024-54792-5 UR - https://m2.mtmt.hu/api/publication/34656926 ID - 34656926 AB - Toluene diamine (TDA) is a major raw material in the polyurethane industry and thus, its production is highly important. TDA is obtained through the catalytic hydrogenation of 2,4-dinitrotoluene (2,4-DNT). In this study a special hydrogenation catalyst has been developed by decomposition cobalt ferrite nanoparticles onto a natural clay-oxide nanocomposite (bentonite) surface using a microwave-assisted solvothermal method. The catalyst particles were examined by TEM and X-ray diffraction. The palladium immobilized on the bentonite crystal surface was identified using an XRD and HRTEM device. The obtained catalyst possesses the advantageous property of being easily separable due to its magnetizability on a natural mineral support largely available and obtained through low carbon- and energy footprint methods. The catalyst demonstrated outstanding performance with a 2,4-DNT conversion rate exceeding 99% along with high yields and selectivity towards 2,4-TDA and all of this achieved within a short reaction time. Furthermore, the developed catalyst exhibited excellent stability, attributed to the strong interaction between the catalytically active metal and its support. Even after four cycles of reuse, the catalytic activity remained unaffected and the Pd content of the catalyst did not change, which indicates that the palladium component remained firmly attached to the magnetic support's surface. LA - English DB - MTMT ER - TY - JOUR AU - Qasim, Hadeer Waleed AU - Hadjadj, Rachid AU - Viskolcz, Béla AU - Fiser, Béla TI - Stoichiometric reaction and catalytic effect of 2-dimethylaminoethanol in urethane formation JF - PHYSICAL CHEMISTRY CHEMICAL PHYSICS J2 - PHYS CHEM CHEM PHYS VL - 26 PY - 2024 IS - 8 SP - 7103 EP - 7108 PG - 6 SN - 1463-9076 DO - 10.1039/D3CP05800J UR - https://m2.mtmt.hu/api/publication/34576072 ID - 34576072 AB - A computational study of the stoichiometric reaction and catalytic effect of 2-dimethylaminoethanol (DMEA) in urethane formation was performed. LA - English DB - MTMT ER -