@article{MTMT:35295916,
	title = {A Bis(Acridino)-Crown Ether for Recognizing Oligoamines in Spermine Biosynthesis},
	url = {https://m2.mtmt.hu/api/publication/35295916},
	author = {Kisfaludi, Péter and Spátay, Sára and Krekó, Marcell and Vezse, Panna and Tóth, Tünde and Huszthy, Péter and Golcs, Ádám},
	doi = {10.3390/molecules29184390},
	journal-iso = {MOLECULES},
	journal = {MOLECULES},
	volume = {29},
	unique-id = {35295916},
	issn = {1420-3049},
	year = {2024},
	eissn = {1420-3049},
	orcid-numbers = {Krekó, Marcell/0000-0002-4972-972X; Huszthy, Péter/0000-0001-7305-3312}
}

@article{MTMT:35295835,
	title = {Vegyületek tisztítása korunk igényeire szabva},
	url = {https://m2.mtmt.hu/api/publication/35295835},
	author = {Golcs, Ádám},
	journal-iso = {TERMÉSZET VILÁGA},
	journal = {TERMÉSZET VILÁGA},
	volume = {155},
	unique-id = {35295835},
	issn = {0040-3717},
	year = {2024},
	pages = {399-403}
}

@article{MTMT:35294237,
	title = {One-Step, Catalyst-Free Continuous-Flow Method for the Rapid and Safe Synthesis of 1-Substituted 1H-Tetrazoles},
	url = {https://m2.mtmt.hu/api/publication/35294237},
	author = {Fülöp, Zsolt and Bana, Péter and Temesvári, Márton and Barabás, Júlia and Kazsu, Zoltán and Béni, Zoltán and Greiner, István and Éles, János},
	doi = {10.1021/acs.oprd.4c00239},
	journal-iso = {ORG PROCESS RES DEV},
	journal = {ORGANIC PROCESS RESEARCH & DEVELOPMENT},
	unique-id = {35294237},
	issn = {1083-6160},
	abstract = {1-Substituted 1H-tetrazoles are valuable building blocks in medicinal chemistry; however, their limited synthetic accessibility constrains their use. A new continuous-flow strategy was developed to safely obtain tetrazoles from primary amines within minutes. Method optimization was aided by theoretical studies leading to different conditions depending on the amine structure. The versatility of our method was demonstrated by using a set of benzylic, aromatic, aliphatic, and heteroaromatic amines leading to previously unexplored tetrazoles with satisfactory yields. © 2024 American Chemical Society.},
	keywords = {SAFETY; TETRAZOLES; theoretical study; MEDICINAL CHEMISTRY; Continuous-flow; Continuous-flow; Optimisations; Primary amines; Building blockes; catalyst-free; Theoretical studies; 1H-tetrazole; 1H-tetrazoles; Continuous flow methods},
	year = {2024},
	eissn = {1520-586X},
	orcid-numbers = {Fülöp, Zsolt/0000-0001-8423-1583}
}

@article{MTMT:35221562,
	title = {Ruthenium-catalyzed “open-loop” recycling of polyethylene via tandem isomerization-metathesis (ISOMET)},
	url = {https://m2.mtmt.hu/api/publication/35221562},
	author = {Farkas, Vajk and Albrecht, Pascal and Erdélyi, Ádám and Nagyházi, Márton and Csutorás, Beatrix and Turczel, Gábor and Miskolczi, Norbert and Bobek-Nagy, Janka and Osterthun, Ole and Klankermayer, Jürgen and Tuba, Róbert},
	doi = {10.1039/D4GC03912B},
	journal-iso = {GREEN CHEM},
	journal = {GREEN CHEMISTRY},
	unique-id = {35221562},
	issn = {1463-9262},
	abstract = {The highly efficient conversion of post-consumer PE waste into propylene by single metal-catalyzed isomerization-metathesis (ISOMET) opens up new alternatives for persistent plastic waste upcycling.},
	year = {2024},
	eissn = {1463-9270},
	orcid-numbers = {Farkas, Vajk/0000-0002-1189-0032; Albrecht, Pascal/0009-0008-3700-5135; Erdélyi, Ádám/0009-0008-0715-8907; Csutorás, Beatrix/0009-0003-5214-9042; Turczel, Gábor/0000-0002-6753-6796; Miskolczi, Norbert/0000-0003-4862-0148; Osterthun, Ole/0000-0002-9324-6864; Klankermayer, Jürgen/0000-0003-2143-9402}
}

@article{MTMT:35218635,
	title = {Synthetic Modifications of a Pb2+-Sensor Acridono-Crown Ether for Covalent Attachment and Their Effects on Selectivity},
	url = {https://m2.mtmt.hu/api/publication/35218635},
	author = {Vezse, Panna and Gede, M. and Golcs, Ádám and Huszthy, Péter and Tóth, Tünde},
	doi = {10.3390/molecules29051121},
	journal-iso = {MOLECULES},
	journal = {MOLECULES},
	volume = {29},
	unique-id = {35218635},
	issn = {1420-3049},
	year = {2024},
	eissn = {1420-3049},
	orcid-numbers = {Huszthy, Péter/0000-0001-7305-3312}
}

@article{MTMT:35218123,
	title = {Synthesis and Studies of 9-Activated 4,5-Dimethoxyacridine Multifunctionalizable Building Blocks},
	url = {https://m2.mtmt.hu/api/publication/35218123},
	author = {Vezse, Panna and Golcs, Ádám and Huszthy, Péter and Tóth, Tünde},
	doi = {10.3311/PPch.23808},
	journal-iso = {PERIOD POLYTECH CHEM ENG},
	journal = {PERIODICA POLYTECHNICA-CHEMICAL ENGINEERING},
	volume = {68},
	unique-id = {35218123},
	issn = {0324-5853},
	year = {2024},
	eissn = {1587-3765},
	pages = {277-286},
	orcid-numbers = {Huszthy, Péter/0000-0001-7305-3312}
}

@article{MTMT:35218095,
	title = {Covalently Modified Molecular-Recognition-Capable UV-Transparent Microplate for Ultra-High-Throughput Screening of Dissolved Zn2+ and Pb2+},
	url = {https://m2.mtmt.hu/api/publication/35218095},
	author = {Ádám, B.Á. and Kis-Tót, B. and Jávor, B. and László, Szabolcs and Vezse, Panna and Huszthy, Péter and Tóth, Tünde and Golcs, Ádám},
	doi = {10.3390/s24144529},
	journal-iso = {SENSORS-BASEL},
	journal = {SENSORS},
	volume = {24},
	unique-id = {35218095},
	year = {2024},
	eissn = {1424-8220},
	orcid-numbers = {Huszthy, Péter/0000-0001-7305-3312}
}

@article{MTMT:35218062,
	title = {Ultrafast Solid-Phase Oxidation of Aldehydes to Carboxylic Acids by Atmosphseric Plasma Treatment},
	url = {https://m2.mtmt.hu/api/publication/35218062},
	author = {Ádám, B.A. and Golcs, Ádám and Tóth, Tünde and Huszthy, Péter},
	doi = {10.1021/acsomega.4c01596},
	journal-iso = {ACS OMEGA},
	journal = {ACS OMEGA},
	volume = {9},
	unique-id = {35218062},
	issn = {2470-1343},
	year = {2024},
	eissn = {2470-1343},
	pages = {27269-27277},
	orcid-numbers = {Huszthy, Péter/0000-0001-7305-3312}
}

@article{MTMT:35198234,
	title = {In-line indirect concentration measurement of ultralow dose API during twin-screw wet granulation based on NIR and Raman spectroscopy},
	url = {https://m2.mtmt.hu/api/publication/35198234},
	author = {Galata, Dorián László and Domokos, András and Démuth, Balázs and Záhonyi, Petra and Fülöp, Gergő and Nagy, Zsombor Kristóf and Nagy, Brigitta},
	doi = {10.1016/j.ijpharm.2024.124650},
	journal-iso = {INT J PHARM},
	journal = {INTERNATIONAL JOURNAL OF PHARMACEUTICS},
	volume = {664},
	unique-id = {35198234},
	issn = {0378-5173},
	year = {2024},
	eissn = {1873-3476},
	orcid-numbers = {Domokos, András/0000-0003-1968-4679}
}

@article{MTMT:35196297,
	title = {The PARP inhibitor rucaparib blocks SARS-CoV-2 virus binding to cells and the immune reaction in models of COVID-19},
	url = {https://m2.mtmt.hu/api/publication/35196297},
	author = {Papp, H. and Tóth, Emese and Bóvári-Biri, J. and Bánfai, K. and Juhász, P. and Mahdi, M. and Russo, L.C. and Bajusz, Dávid and Sipos, Adrienn and Petri, László and Szalai, Tibor Viktor and Kemény, Ágnes and Madai, M. and Kuczmog, A. and Batta, Gyula and Mózner, Orsolya and Vaskó, Dorottya and Hirsch, Edit and Bohus, P. and Méhes, G. and Tőzsér, J. and Curtin, N.J. and Helyes, Zsuzsanna and Tóth, A. and Hoch, N.C. and Jakab, F. and Keserű, György Miklós and Pongrácz, J.E. and Bay, Péter},
	doi = {10.1111/bph.17305},
	journal-iso = {BR J PHARMACOL},
	journal = {BRITISH JOURNAL OF PHARMACOLOGY},
	unique-id = {35196297},
	issn = {0007-1188},
	abstract = {Background and Purpose: To date, there are limited options for severe Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 virus. As ADP-ribosylation events are involved in regulating the life cycle of coronaviruses and the inflammatory reactions of the host; we have, here, assessed the repurposing of registered PARP inhibitors for the treatment of COVID-19. Experimental Approach: The effects of PARP inhibitors on virus uptake were assessed in cell-based experiments using multiple variants of SARS-CoV-2. The binding of rucaparib to spike protein was tested by molecular modelling and microcalorimetry. The anti-inflammatory properties of rucaparib were demonstrated in cell-based models upon challenging with recombinant spike protein or SARS-CoV-2 RNA vaccine. Key Results: We detected high levels of oxidative stress and strong PARylation in all cell types in the lungs of COVID-19 patients, both of which negatively correlated with lymphocytopaenia. Interestingly, rucaparib, unlike other tested PARP inhibitors, reduced the SARS-CoV-2 infection rate through binding to the conserved 493–498 amino acid region located in the spike-ACE2 interface in the spike protein and prevented viruses from binding to ACE2. In addition, the spike protein and viral RNA-induced overexpression of cytokines was down-regulated by the inhibition of PARP1 by rucaparib at pharmacologically relevant concentrations. Conclusion and Implications: These results point towards repurposing rucaparib for treating inflammatory responses in COVID-19. © 2024 The Author(s). British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.},
	keywords = {NFκB; rucaparib; ACE2; COVID-19; SARS-CoV-2 spike protein; SARS-CoV-2 RNA; viral lung inflammation},
	year = {2024},
	eissn = {1476-5381},
	orcid-numbers = {Bajusz, Dávid/0000-0003-4277-9481; Kemény, Ágnes/0000-0002-4523-3938; Batta, Gyula/0000-0002-0442-1828; Mózner, Orsolya/0000-0001-5784-7702; Vaskó, Dorottya/0000-0002-2502-0644}
}