TY - JOUR AU - Kondor, Ariella Edina AU - Vereczkei, András AU - Varga, Péter AU - Sindler, Dóra Lili AU - Gowda, Yashwanth Sudheendra AU - Dergez, Tímea AU - Garcia, Elisabeth AU - Csontos, Armand AU - Faluhelyi, Nándor AU - Hegedűs, Ivett AU - Bogner, Barna AU - Baracs, József TI - The Role of MRI in the Preoperative Staging of Rectal Cancer : Ten-year Experience from a Single Tertiary Center JF - ANTICANCER RESEARCH J2 - ANTICANCER RES VL - 46 PY - 2026 IS - 4 SP - 2125 EP - 2132 PG - 8 SN - 0250-7005 DO - 10.21873/anticanres.18101 UR - https://m2.mtmt.hu/api/publication/37050602 ID - 37050602 N1 - Cited by: 0 AB - Accurate preoperative staging of rectal cancer (CRC) guides treatment decisions, particularly regarding neoadjuvant chemoradiotherapy. Although magnetic resonance imaging (MRI) is recommended for local staging, questions persist regarding whether T stage or circumferential resection margin (CRM) involvement is the stronger predictor of treatment necessity. This study evaluated ten years of institutional experience to determine whether MRI-based CRM assessment provides superior prognostic guidance compared to tumor-node-metastasis (TNM) staging alone.Between March 2014 and July 2023, 659 patients underwent surgery for histologically confirmed rectal adenocarcinoma; 258 received preoperative MRI and computed tomography (CT) imaging. After applying exclusion criteria (neoadjuvant therapy prior to surgery, transanal endoscopic procedures, patient refusal, contraindications), 114 patients undergoing primary surgical resection comprised the study cohort. MRI- and CT-derived T and N stages and CRM involvement were compared with definitive histopathological findings using chi-squared, Fisher's exact, independent t-tests, Mann-Whitney U-tests, and diagnostic accuracy calculations.MRI correctly predicted pathological T (pT) stage in 47.4% of cases versus CT in 48.2% (p=0.895), indicating no significant difference. CT more frequently underestimated T stage (33.3%), whereas MRI more often overestimated (36.8%, p<0.001). MRI demonstrated higher sensitivity for nodal metastasis (74% vs. 62%), although specificity was lower (39.1% vs. 54.7%). Critically, MRI correctly identified all seven patients with pathological circumferential resection margin (pCRM) ≤1 mm (6.14% of cohort), achieving 100% concordance. Local recurrence occurred in nine patients (7.9%) during follow-up; all received primary surgery based on negative mesorectal fascia (MRF) status on MRI.MRI reliably predicts CRM involvement and MRF status, serving as a key determinant for neoadjuvant chemoradiotherapy decisions. In patients with T3 tumors and negative MRF status on MRI, primary resection remains oncologically safe, avoiding unnecessary chemoradiotherapy-related morbidity while maintaining acceptable recurrence rates comparable to literature data. LA - English DB - MTMT ER - TY - JOUR AU - Papp, Csenge AU - Sindler, Dóra Lili AU - Palkovics, András AU - Csontos, Armand AU - Sándor, Zoltán AU - Németh, Balázs AU - Vereczkei, András AU - Papp, András TI - Early Oral Feeding in Patients Undergoing Upper Gastrointestinal Surgery : A Propensity Score-matching Study JF - IN VIVO J2 - IN VIVO VL - 39 PY - 2025 IS - 1 SP - 335 EP - 339 PG - 5 SN - 0258-851X DO - 10.21873/invivo.13832 UR - https://m2.mtmt.hu/api/publication/35696301 ID - 35696301 N1 - Department of Surgery, Clinical Center, Medical School, University of Pécs, Pécs, Hungary Department of Public Health Medicine, Medical School, University of Pécs, Pécs, Hungary Export Date: 16 January 2025 CODEN: IVIVE Correspondence Address: Papp, C.; Department of Surgery, Szigeti Str. 12, Hungary; email: pappcse@gmail.com AB - Enhanced recovery after surgery (ERAS) protocol is adopted in clinical practice worldwide, but a lack of evidence for measurable benefits after upper gastrointestinal (GI) surgeries can be detected especially regarding early oral feeding.A propensity score-matching study was conducted at the Department of Surgery of the University of Pécs between January 2020 and December 2023. The study included patients who underwent upper GI cancer surgery and were treated according to an early oral feeding protocol (EOF). Investigational and control groups were analyzed and compared from prospectively collected datasets.We enrolled 72 patients, 36 in the EOF group, and 36 case-matched patients in the traditional late oral feeding (LOF) group. Oral feeding in the EOF group started on an average of 1.94 days postoperatively, while in the LOF group, it began on an average of 5.72 days postoperatively. EOF could reduce the average length of hospital stay. Statistically significant decreases were observed in the EOF group concerning the time until the first bowel movements, and the length of postoperative intravenous fluid therapy. No significant differences were detected regarding mortality, anastomosis insufficiency, inflammation and stricture or seroma formation.Early oral nutritional support positively impacts the recovery of patients following upper GI surgery without increasing mortality or anastomosis insufficiency rates compared to traditional protocols. Significant improvements were observed in quality of life indicators for patients in the early oral feeding group. This approach aligns with ERAS goals and suggests a valuable strategy for postoperative care in upper GI cancer surgeries. LA - English DB - MTMT ER - TY - JOUR AU - Sindler, Dóra Lili AU - Papp, Csenge AU - Csontos, Armand AU - Szakó, Lajos AU - Vereczkei, András AU - Halvax, Péter Ákos AU - Palkovics, András AU - Papp, András TI - A korai, szájon keresztüli táplálás nem jelent veszélyt a felső tápcsatornai műtétek után : Becsült részvételi valószínűség szerinti párosítási tanulmány JF - ORVOSI HETILAP J2 - ORV HETIL VL - 165 PY - 2024 IS - 1 SP - 24 EP - 29 PG - 6 SN - 0030-6002 DO - 10.1556/650.2024.32936 UR - https://m2.mtmt.hu/api/publication/34506134 ID - 34506134 N1 - Export Date: 09 April 2025; CODEN: ORHEA LA - Hungarian DB - MTMT ER - TY - JOUR AU - Csontos, Armand AU - Németh, Dávid AU - Szakó, Lajos AU - Berke, Gergő AU - Sindler, Dóra Lili AU - Berki, Dávid AU - Papp, Csenge AU - Hegyi, Péter AU - Vereczkei, András AU - Papp, András TI - Intraoperative pyloric drainage is unnecessary during esophagectomies: a meta-analysis and systematic review of randomized controlled trials JF - PATHOLOGY AND ONCOLOGY RESEARCH J2 - PATHOL ONCOL RES VL - 30 PY - 2024 PG - 11 SN - 1219-4956 DO - 10.3389/pore.2024.1611823 UR - https://m2.mtmt.hu/api/publication/35169697 ID - 35169697 N1 - Export Date: 09 April 2025; CODEN: POREF AB - Objective: The topic of this meta-analysis is the comparison of gastric conduit esophageal reconstructions with or without pyloroplasty. LA - English DB - MTMT ER - TY - JOUR AU - Papp, András AU - Palkovics, András AU - Sindler, Dóra Lili AU - Papp, Csenge AU - Halvax, Péter Ákos AU - Czimmer, József AU - Nagy, Bálint AU - Vereczkei, András TI - Achalasia miatt végzett robotasszisztált laparoszkópos cardiomyotomia és fundoplicatio (Heller–Dor-műtét) JF - ORVOSI HETILAP J2 - ORV HETIL VL - 164 PY - 2023 IS - 14 SP - 542 EP - 547 PG - 6 SN - 0030-6002 DO - 10.1556/650.2023.32748 UR - https://m2.mtmt.hu/api/publication/33754879 ID - 33754879 AB - The outcomes of surgical interventions for achalasia treatment improved with the advent of minimally invasive surgery. Robotic-assisted Heller-Dor's (RAHD) procedure established over the last years, provides important advantages to surgeons, such as binocular three-dimensional vision and improvement of fine motor control.Between October and December of 2022, first in Hungary, 3 patients (37-year-old man, 55- and 72-year-old women) underwent RAHD procedure for achalasia at the Clinical Centre of the University of Pécs using the da Vinci Xi system.RAHD procedure was feasible without any particular problems and the postoperative course of all three patients was uneventful. The operation times were 198, 204 and 238 minutes, including 23, 19 and 14 minutes for the setup time of the robot. By the last patient, due to an accompanying hiatal hernia, an additional hiatal reconstruction was also performed. In the first 2 cases, the patients were discharged on the 4th postoperative day, while in the last case, with the additional hiatal reconstruction, the patient was emitted on the 6th postoperative day.There are several published studies about RAHD cardiomyotomy. The general conclusion is that, in experienced hands, RAHD procedure is easy to perform, ensures a meticulous esophageal and gastric myotomy, allowing to visualize and divide each muscle fiber with a significantly lower rate of mucosal perforations. However, by RAHD procedure, the overall costs are higher, including a longer operation time during the learning curve. At the same time, the avoidance of mucosal lacerations and their possible consequences has to be weighed against the higher overall costs.Laparoscopic cardiomyotomy is the first standard upper-gastrointestinal operation where a clear advantage of the use of a surgical robot has been proven. Thus, wherever this equipment is available, it should be preferred for this procedure. Orv Hetil. 2023; 164(14): 542-547. LA - Hungarian DB - MTMT ER - TY - JOUR AU - Sindler, Dóra Lili AU - Mátrai, Péter AU - Szakó, Lajos AU - Berki, Dávid AU - Berke, Gergő AU - Csontos, Armand AU - Papp, Csenge AU - Hegyi, Péter AU - Papp, András TI - Faster recovery and bowel movement after early oral feeding compared to late oral feeding after upper GI tumor resections: a meta-analysis JF - FRONTIERS IN SURGERY J2 - FRONT SURG VL - 10 PY - 2023 PG - 11 SN - 2296-875X DO - 10.3389/fsurg.2023.1092303 UR - https://m2.mtmt.hu/api/publication/34011864 ID - 34011864 N1 - Export Date: 09 April 2025 LA - English DB - MTMT ER -