@article{MTMT:34724787, title = {Trans isomeric fatty acids in human milk and their role in infant health and development}, url = {https://m2.mtmt.hu/api/publication/34724787}, author = {Hatem, Okba and Kaçar, Ömer Furkan and Kaçar, Hüsna Kaya and Szentpéteri, József László (Joe Petersburger) and Marosvölgyi, Tamás and Szabó, Éva}, doi = {10.3389/fnut.2024.1379772}, journal-iso = {FRONT NUTR}, journal = {FRONTIERS IN NUTRITION}, volume = {11}, unique-id = {34724787}, issn = {2296-861X}, abstract = {It is well known that long chain polyunsaturated fatty acids (LCPUFAs) play an important role in neurodevelopment in the perinatal life. The most important source of these fatty acids is the diet, however, they can also be formed in the human body from their shorter chain precursors, the essential fatty acids. Since the WHO recommends exclusive breastfeeding for the first six months after birth, the exclusive source of these fatty acids for breastfed infants is human milk, which can be influenced by the mother’s diet. Unsaturated fatty acids can have either cis or trans configuration double bond in their chain with distinct physiological effects. Cis isomeric unsaturated fatty acids have several beneficial effects, while trans isomers are mostly detrimental, because of their similar structure to saturated fatty acids. Trans fatty acids (TFAs) can be further subdivided into industrial (iTFA) and ruminant-derived trans fatty acids (rTFA). However, the physiological effects of these two TFA subgroups may differ. In adults, dietary intake of iTFA has been linked to atherosclerosis, insulin resistance, obesity, chronic inflammation, and increased development of certain cancers, among other diseases. However, iTFAs can have a negative impact on health not only in adulthood but in childhood too. Results from previous studies have shown that iTFAs have a significant negative effect on LCPUFA levels in the blood of newborns and infants. In addition, iTFAs can affect the growth and development of infants, and animal studies suggest that they might even have lasting negative effects later in life. Since the only source of TFAs in the human body is the diet, the TFA content of breast milk may determine the TFA supply of breastfed infants and thus affect the levels of LCPUFAs important for neurodevelopment and the health of infants. In this review, we aim to provide an overview of the TFA content in human milk available in the literature and their potential effects on infant health and development.}, year = {2024}, eissn = {2296-861X}, orcid-numbers = {Marosvölgyi, Tamás/0000-0002-4244-5513} } @article{MTMT:34476390, title = {A second update on mapping the human genetic architecture of COVID-19.}, url = {https://m2.mtmt.hu/api/publication/34476390}, doi = {10.1038/s41586-023-06355-3}, journal-iso = {NATURE}, journal = {NATURE}, volume = {621}, unique-id = {34476390}, issn = {0028-0836}, year = {2023}, eissn = {1476-4687}, pages = {E7-E26} } @misc{MTMT:34397010, title = {TRADITIONAL EASTER EGGS - A UNIQUE METHOD TO DEVELOP MOTORIC SKILLS OF MEDICAL AND DENTISTRY STUDENTS}, url = {https://m2.mtmt.hu/api/publication/34397010}, isbn = {9789533880051}, author = {Szentpéteri, József László (Joe Petersburger) and Krizalkovicová, Zuzana and Fellenbeck, Dávid and Dávid, Kinga}, unique-id = {34397010}, year = {2023} } @misc{MTMT:34397000, title = {STUDY OF CENTRAL NERVOUS SYSTEM DEVELOPMENT IN PRESCHOOL-AGED CHILDREN WITH OR WITHOUT SNI OR BTM STATUS USING JUDO SPORT}, url = {https://m2.mtmt.hu/api/publication/34397000}, author = {Krizalkovicová, Zuzana and Makai, Alexandra and Szentpéteri, József László (Joe Petersburger)}, unique-id = {34397000}, year = {2023}, orcid-numbers = {Makai, Alexandra/0000-0002-1907-120X} } @misc{MTMT:34396781, title = {MEASURING OXYTOCIN IN A SPORT CONTEXT. SYSTEMATIC LITERATURE REVIEW}, url = {https://m2.mtmt.hu/api/publication/34396781}, isbn = {9789533880051}, author = {Szabó, Péter and Sara, Bonet and Hetényi, Roland and Hanna, Dániel and Lohner, Szimonetta and Prisztóka, Gyöngyvér and Szentpéteri, József László (Joe Petersburger)}, unique-id = {34396781}, year = {2023} } @misc{MTMT:34102938, title = {A second update on mapping the human genetic architecture of COVID-19}, url = {https://m2.mtmt.hu/api/publication/34102938}, author = {Andrea, Ganna}, unique-id = {34102938}, year = {2023} } @article{MTMT:34081449, title = {A comparative study to optimize experimental conditions of pentylenetetrazol and pilocarpine-induced epilepsy in zebrafish larvae}, url = {https://m2.mtmt.hu/api/publication/34081449}, author = {Szép, Dávid and Dittrich, Bianka and Görbe, Anikó and Szentpéteri, József László (Joe Petersburger) and Aly, Nour and Jin, Meng and Budán, Ferenc Csaba and Sík, Attila}, doi = {10.1371/journal.pone.0288904}, journal-iso = {PLOS ONE}, journal = {PLOS ONE}, volume = {18}, unique-id = {34081449}, issn = {1932-6203}, abstract = {A common way to investigate epilepsy and the effect of antiepileptic pharmaceuticals is to analyze the movement patterns of zebrafish larvae treated with different convulsants like pentylenetetrazol (PTZ), pilocarpine, etc. Many articles have been written on this topic, but the research methods and exact settings are not sufficiently defined in most. Here we designed and executed a series of experiments to optimize and standardize the zebrafish epilepsy model. We found that during the light and the dark trials, the zebrafish larvae moved significantly more in the light, independent of the treatment, both in PTZ and pilocarpine-treated and the control groups. As expected, zebrafish larvae treated with convulsants moved significantly more than the ones in the control group, although this difference was higher between the individuals treated with PTZ than pilocarpine. When examining the optimal observation time, we divided the half-hour period into 5-minute time intervals, and between these, the first 5 minutes were found to be the most different from the others. There were fewer significant differences in the total movement of larvae between the other time intervals. We also performed a linear regression analysis with the cumulative values of the distance moved during the time intervals that fit the straight line. In conclusion, we recommend 30 minutes of drug pretreatment followed by a 10-minute test in light conditions with a 5-minute accommodation time. Our result paves the way toward improved experimental designs using zebrafish to develop novel pharmaceutical approaches to treat epilepsy.}, year = {2023}, eissn = {1932-6203} } @misc{MTMT:34016115, title = {Érzelemszabályozási Problémák és az Asszertivitás összehasonlítása a Brazil Jiu-Jitsu (BJJ) viszonylatában. Sportpszichológia}, url = {https://m2.mtmt.hu/api/publication/34016115}, author = {Szabó, Péter and Szentpéteri, József László (Joe Petersburger) and Csókási, Krisztina and Kovács, Zsófia and Prisztóka, Gyöngyvér}, unique-id = {34016115}, abstract = {A Brazil Jiu-Jitsu (BJJ) kapcsolata az iskolai zaklatással már több tanulmány vizsgálatának volt tárgya. A sport egyre gyakrabban igazoltan hasznos eszköz a bullying és poszttraumás stresszel kapcsolatos terápiás folyamatokban. Jelen vizsgálat célja az volt, hogy összehasonlítsuk egy BJJ-t gyakorló csoport értékeit egy más sportot űző és egy egyáltalán nem sportoló csoport értékeivel. Tanulmányunk az asszertivitásra, az érzelemszabályozási nehézségekre és az agresszióra összpontosított, amelyeknek komoly szerepe van az áldozattá válás prevenciójában és a rehabilitáció folyamataiban.}, year = {2023}, orcid-numbers = {Csókási, Krisztina/0000-0002-5197-3844} } @misc{MTMT:34007269, title = {"Speak Up!" - Communication Skills and Language Development}, url = {https://m2.mtmt.hu/api/publication/34007269}, author = {Szentpéteri, József László (Joe Petersburger) and Szabó, Péter}, unique-id = {34007269}, year = {2023} } @article{MTMT:33832899, title = {Higher Availability of Long-Chain Monounsaturated Fatty Acids in Preterm than in Full-Term Human Milk}, url = {https://m2.mtmt.hu/api/publication/33832899}, author = {Marosvölgyi, Tamás and Dergez, Tímea and Szentpéteri, József László (Joe Petersburger) and Szabó, Éva and Decsi, Tamás}, doi = {10.3390/life13051205}, journal-iso = {LIFE-BASEL}, journal = {LIFE-BASEL}, volume = {13}, unique-id = {33832899}, abstract = {While the role of n-3 and n-6 long-chain polyunsaturated fatty acids (LCPUFAs) in the maturation of the infantile nervous system is extensively studied and relatively well-characterized, data on the potential developmental importance of the n-9 long-chain monounsaturated fatty acid (LCMUFA), nervonic acid (NA, C24:1n-9) are scarce and ambiguous. Therefore, the aim of the present study was to reanalyze our available data on the contribution of NA and its LCMUFA precursors, gondoic acid (C20:1n-9) and erucic acid (EA, C22:1n-9) to the fatty acid composition of human milk (HM) during the first month of lactation in mothers of both preterm (PT) and full-term (FT) infants. HM samples were obtained daily during the first week of lactation, and then on the 14th, 21st, and 28th days. Values of the LCMUFAs, C20:1n-9, EA, and NA were significantly higher in colostrum than in transient and mature HM. Consequently, there were highly significant inverse associations between LCMUFA values and the duration of lactation. Moreover, C20:1n-9, EA, and NA values were monotonously, considerably, and at many timepoints significantly higher in PT than in FT HM samples. By the 28th day of lactation, summarized LCMUFA values in PT HM samples declined to the level measured in FT HM samples on the first day of lactation; however, EA and NA values were still significantly higher in PT than in FT HM on the 28th day. Significantly higher availability of LCMUFAs in PT than in FT HM underpins the potential biological role of this hitherto somewhat neglected group of fatty acids.}, year = {2023}, eissn = {2075-1729}, orcid-numbers = {Marosvölgyi, Tamás/0000-0002-4244-5513; Szentpéteri, József László (Joe Petersburger)/0000-0001-8685-5189} }