@mastersthesis{MTMT:34115897, title = {Application of the Quality by Design methodology in the design and development process of liposomal delivery systems [Quality by Design módszertan alkalmazása liposzómális szállítórendszerek tervezési és fejlesztési folyamatában]}, url = {https://m2.mtmt.hu/api/publication/34115897}, author = {Németh, Zsófia}, doi = {10.14232/phd.11453}, publisher = {Universití of Szeged}, unique-id = {34115897}, year = {2022}, orcid-numbers = {Németh, Zsófia/0000-0003-3953-9831} } @misc{MTMT:33692135, title = {Hatóanyag-tartalmú liposzómák előállítása és jellemzése}, url = {https://m2.mtmt.hu/api/publication/33692135}, author = {Dobó, Dorina Gabriella and Németh, Zsófia and Reza, Semnani and Pannonhalminé Csóka, Ildikó}, unique-id = {33692135}, year = {2022}, orcid-numbers = {Németh, Zsófia/0000-0003-3953-9831; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781} } @CONFERENCE{MTMT:33199232, title = {Liposzómás készítmények gyártástechnológiai fejlesztése}, url = {https://m2.mtmt.hu/api/publication/33199232}, author = {Dobó, Dorina Gabriella and Németh, Zsófia and Sipos, Bence and Reza, Semnani Jazani and Pannonhalminé Csóka, Ildikó}, booktitle = {Gyógyszertechnológiai és Ipari Gyógyszerészeti Konferencia 2022: A Magyar Gyógyszerésztudományi Társaság Gyógyszeripari Szervezetének és Gyógyszertechnológiai Szakosztályának Konferenciája}, unique-id = {33199232}, year = {2022}, pages = {50-50}, orcid-numbers = {Németh, Zsófia/0000-0003-3953-9831; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781} } @article{MTMT:33070907, title = {Quality by Design-Driven Zeta Potential Optimisation Study of Liposomes with Charge Imparting Membrane Additives}, url = {https://m2.mtmt.hu/api/publication/33070907}, author = {Németh, Zsófia and Pannonhalminé Csóka, Ildikó and Semnani Jazani, Reza and Sipos, Bence and Haspel, Henrik and Kozma, Gábor and Kónya, Zoltán and Dobó, Dorina Gabriella}, doi = {10.3390/pharmaceutics14091798}, journal-iso = {PHARMACEUTICS}, journal = {PHARMACEUTICS}, volume = {14}, unique-id = {33070907}, issn = {1999-4923}, abstract = {Liposomal formulations, as versatile nanocarrier systems suitable for targeted delivery, have a highly focused role in the therapy development of unmet clinical needs and diagnostic imaging techniques. Formulating nanomedicine with suitable zeta potential is an essential but challenging task. Formulations with a minimum ±30 mV zeta potential are considered stable. The charge of the phospholipid bilayer can be adjusted with membrane additives. The present Quality by Design-derived study aimed to optimise liposomal formulations prepared via the thin-film hydration technique by applying stearylamine (SA) or dicetyl phosphate (DCP) as charge imparting agents. This 32 fractional factorial design-based study determined phosphatidylcholine, cholesterol, and SA/DCP molar ratios for liposomes with characteristics meeting the formulation requirements. The polynomials describing the effects on the zeta potential were calculated. The optimal molar ratios of the lipids were given as 12.0:5.0:5.0 for the SA-PBS pH 5.6 (optimised sample containing stearylamine) and 8.5:4.5:6.5 for the DCP-PBS pH 5.6 (optimised sample containing dicetyl phosphate) particles hydrated with phosphate-buffered saline pH 5.6. The SA-PBS pH 5.6 liposomes had a vesicle size of 108 ± 15 nm, 0.20 ± 0.04 polydispersity index, and +30.1 ± 1.2 mV zeta potential, while these values were given as 88 ± 14 nm, 0.21 ± 0.02, and −36.7 ± 3.3 mV for the DCP-PBS pH 5.6 vesicles. The prepared liposomes acquired the requirements of the zeta potential for stable formulations.}, year = {2022}, eissn = {1999-4923}, orcid-numbers = {Németh, Zsófia/0000-0003-3953-9831; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781; Sipos, Bence/0000-0002-0131-4728; Haspel, Henrik/0000-0002-1362-2752; Kozma, Gábor/0000-0003-2033-0720; Kónya, Zoltán/0000-0002-9406-8596; Dobó, Dorina Gabriella/0000-0001-9528-9983} } @CONFERENCE{MTMT:32846146, title = {Knowledge space development and risk assessment-based evaluation on hyperlipidaemia-related patient adherence}, url = {https://m2.mtmt.hu/api/publication/32846146}, author = {Sipos, Bence and Németh, Zsófia and Kisvári, Edit Mária and Pannonhalminé Csóka, Ildikó}, booktitle = {XXV. Tavaszi Szél Konferencia 2022. Absztraktkötet}, unique-id = {32846146}, year = {2022}, pages = {748-748}, orcid-numbers = {Sipos, Bence/0000-0002-0131-4728; Németh, Zsófia/0000-0003-3953-9831; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781} } @article{MTMT:32707423, title = {Pharmaceutical Development and Design of Thermosensitive Liposomes Based on the QbD Approach}, url = {https://m2.mtmt.hu/api/publication/32707423}, author = {Dobó, Dorina Gabriella and Németh, Zsófia and Sipos, Bence and Cseh, Martin and Pallagi, Edina and Berkesi, Dániel Simon and Kozma, Gábor and Kónya, Zoltán and Pannonhalminé Csóka, Ildikó}, doi = {10.3390/molecules27051536}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {27}, unique-id = {32707423}, issn = {1420-3049}, year = {2022}, eissn = {1420-3049}, orcid-numbers = {Németh, Zsófia/0000-0003-3953-9831; Sipos, Bence/0000-0002-0131-4728; Kozma, Gábor/0000-0003-2033-0720; Kónya, Zoltán/0000-0002-9406-8596; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781} } @{MTMT:32613069, title = {Pharmaceutical study of essential oil-loaded liposomal formulations}, url = {https://m2.mtmt.hu/api/publication/32613069}, author = {Reza, Semnani Jazani and Németh, Zsófia and Dobó, Dorina Gabriella and Pannonhalminé Csóka, Ildikó}, booktitle = {IV. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science : book of abstracts}, doi = {10.14232/syrptbrs.2022.59}, unique-id = {32613069}, year = {2022}, pages = {59-59}, orcid-numbers = {Németh, Zsófia/0000-0003-3953-9831; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781} } @{MTMT:32612795, title = {Risk-based optimization of liposome-based nano-carrier systems}, url = {https://m2.mtmt.hu/api/publication/32612795}, author = {Németh, Zsófia and Reza, Semnani Jazani and Sipos, Bence and Dobó, Dorina Gabriella and Pallagi, Edina and Pannonhalminé Csóka, Ildikó}, booktitle = {IV. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science : book of abstracts}, doi = {10.14232/syrptbrs.2022.44}, unique-id = {32612795}, year = {2022}, pages = {44-44}, orcid-numbers = {Németh, Zsófia/0000-0003-3953-9831; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781} } @misc{MTMT:32748244, title = {Essential oils and liposomes – Potentials in their pharmaceutical use}, url = {https://m2.mtmt.hu/api/publication/32748244}, author = {Reza, Semnani Jazani and Németh, Zsófia and Dobó, Dorina Gabriella and Pannonhalminé Csóka, Ildikó}, unique-id = {32748244}, year = {2021}, orcid-numbers = {Németh, Zsófia/0000-0003-3953-9831; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781} } @CONFERENCE{MTMT:32612742, title = {Liposzóma alapú nano-hordozórendszerek kockázatbecslésre épülő optimalizálása}, url = {https://m2.mtmt.hu/api/publication/32612742}, author = {Németh, Zsófia and Sipos, Bence and Reza, Semnani Jazani and Dobó, Dorina Gabriella}, booktitle = {XIV. Clauder Ottó Emlékverseny 2021.}, unique-id = {32612742}, year = {2021}, pages = {28-28}, orcid-numbers = {Németh, Zsófia/0000-0003-3953-9831} }