TY - CHAP AU - Maróti, Péter AU - Schlégl, Ádám Tibor AU - Nagy, Bálint AU - Tóth, Luca AU - Bogár, Péter Zoltán AU - Józsa, Gergő AU - Rendeki, Szilárd AU - Mallakpour, Shadpour AU - Hussain, Chaudhery Mustansar TI - Additive manufacturing in limb prosthetics and orthotics: the past, present and future of 3D printing orthopedic assistive devices T2 - Medical Additive Manufacturing PB - Elsevier SN - 9780323953832 PY - 2024 SP - 179 EP - 207 PG - 29 DO - 10.1016/B978-0-323-95383-2.00028-7 UR - https://m2.mtmt.hu/api/publication/34774903 ID - 34774903 LA - English DB - MTMT ER - TY - JOUR AU - Shenker, Benjámin AU - Fehér, Melinda AU - Erdősi, Petra AU - Papp, Leila AU - Vadai, Kitti AU - Hrivnák, Gergely AU - Tóth, Luca AU - Maróti, Péter AU - Horváth, Csaba AU - Cserháti, Péter TI - Examining the Efficacy of Lower Extremity Exoskeletons in the Rehabilitation Process of Spinal Cord Injury Patients. Case Studies TS - Case Studies JF - ACTA POLYTECHNICA HUNGARICA J2 - ACTA POLYTECH HUNG VL - 20 PY - 2023 IS - 8 SP - 111 EP - 131 PG - 21 SN - 1785-8860 DO - 10.12700/APH.20.8.2023.8.7 UR - https://m2.mtmt.hu/api/publication/34568744 ID - 34568744 LA - English DB - MTMT ER - TY - JOUR AU - Akay, Y. AU - Tóth, Luca TI - Successful International EMBS Conference on Biomedical Engineering and Innovation Held in Hungary JF - IEEE PULSE J2 - IEEE PULSE VL - 13 PY - 2022 IS - 6 SP - 33 EP - 36 PG - 4 SN - 2154-2287 DO - 10.1109/MPULS.2022.3227856 UR - https://m2.mtmt.hu/api/publication/33647818 ID - 33647818 LA - English DB - MTMT ER - TY - JOUR AU - Shenker, Benjámin AU - Tóth, Luca AU - Maróti, Péter AU - Fehér, Melinda AU - Cserháti, Péter TI - Gerincvelősérültek alsó végtagi exoszkeletonnal végzett rehabilitációja a COVID-járvány alatt JF - REHABILITÁCIÓ: A MAGYAR REHABILITÁCIÓS TÁRSASÁG FOLYÓIRATA J2 - REHABILITÁCIÓ VL - 32 PY - 2022 IS - 3 SP - 79 EP - 79 PG - 1 SN - 0866-479X UR - https://m2.mtmt.hu/api/publication/33121205 ID - 33121205 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Tóth, Luca AU - Czigler, András AU - Hegedüs, Emőke AU - Komáromy, Hedvig AU - Amrein, Krisztina AU - Czeiter, Endre AU - Yabluchanskiy, Andriy AU - Koller, Ákos AU - Orsi, Gergely AU - Perlaki, Gábor AU - Schwarcz, Attila AU - Büki, András AU - Ungvári, Zoltán István AU - Tóth, Péter József TI - Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults. JF - GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE) J2 - GEROSCIENCE VL - 44 PY - 2022 IS - 6 SP - 2771 EP - 2783 PG - 13 SN - 2509-2715 DO - 10.1007/s11357-022-00623-2 UR - https://m2.mtmt.hu/api/publication/33032134 ID - 33032134 AB - Impairment of moment-to-moment adjustment of cerebral blood flow (CBF) to the increased oxygen and energy requirements of active brain regions via neurovascular coupling (NVC) contributes to the genesis of age-related cognitive impairment. Aging is associated with marked deficiency in the vasoprotective hormone insulin-like growth factor-1 (IGF-1). Preclinical studies on animal models of aging suggest that circulating IGF-1 deficiency is causally linked to impairment of NVC responses. The present study was designed to test the hypotheses that decreases in circulating IGF-1 levels in older adults also predict the magnitude of age-related decline of NVC responses. In a single-center cross-sectional study, we enrolled healthy young (n = 31, 11 female, 20 male, mean age: 28.4 + / - 4.2 years) and aged volunteers (n = 32, 18 female, 14 male, mean age: 67.9 + / - 4.1 years). Serum IGF-1 level, basal CBF (phase contrast magnetic resonance imaging (MRI)), and NVC responses during the trail making task (with transcranial Doppler sonography) were assessed. We found that circulating IGF-1 levels were significantly decreased with age and associated with decreased basal CBF. Age-related decline in IGF-1 levels predicted the magnitude of age-related decline in NVC responses. In conclusion, our study provides additional evidence in support of the concept that age-related circulating IGF-1 deficiency contributes to neurovascular aging, impairing CBF and functional hyperemia in older adults. LA - English DB - MTMT ER - TY - CHAP AU - Tóth, Luca AU - Schiffer, Ádám AU - Pinczker, Veronika AU - Müller, Péter János AU - Büki, András AU - Maróti, Péter ED - Łach, Agnieszka ED - Gorczowska, Magdalena ED - Piaseczna, Natalia TI - Initial Results of Lower Limb Exoskeleton Therapy with Human Gait Analysis for a Paraplegic Patient T2 - Innovations and Developments of Technologies in Medicine, Biology and Healthcare PB - Springer Netherlands CY - Cham SN - 9783030889760 T3 - Advances in Intelligent Systems and Computing, ISSN 2194-5357 ; 1360. PY - 2022 SP - 151 EP - 157 PG - 7 DO - 10.1007/978-3-030-88976-0_20 UR - https://m2.mtmt.hu/api/publication/33027020 ID - 33027020 LA - English DB - MTMT ER - TY - JOUR AU - Környei, Bálint Soma AU - Szabó, Viktor AU - Perlaki, Gábor AU - Balogh, Bendegúz AU - Szabó Steigerwald, Dorottya K. AU - Nagy, Szilvia Anett AU - Tóth, Luca AU - Büki, András AU - Dóczi, Tamás Péter AU - Bogner, Péter AU - Schwarcz, Attila AU - Tóth, Arnold TI - Cerebral Microbleeds May Be Less Detectable by Susceptibility Weighted Imaging MRI From 24 to 72 Hours After Traumatic Brain Injury JF - FRONTIERS IN NEUROSCIENCE J2 - FRONT NEUROSCI-SWITZ VL - 15 PY - 2021 PG - 13 SN - 1662-4548 DO - 10.3389/fnins.2021.711074 UR - https://m2.mtmt.hu/api/publication/32320749 ID - 32320749 N1 - * Megosztott szerzőség AB - Purpose: A former rodent study showed that cerebral traumatic microbleeds (TMBs) may temporarily become invisible shortly after injury when detected by susceptibility weighted imaging (SWI). The present study aims to validate this phenomenon in human SWI. Methods: In this retrospective study, 46 traumatic brain injury (TBI) patients in various forms of severity were included and willingly complied with our strict selection criteria. Clinical parameters potentially affecting TMB count, Rotterdam and Marshall CT score, Mayo Clinic Classification, contusion number, and total volume were registered. The precise time between trauma and MRI [5 h 19 min to 141 h 54 min, including SWI and fluid-attenuated inversion recovery (FLAIR)] was individually recorded; TMB and FLAIR lesion counts were assessed. Four groups were created based on elapsed time between the trauma and MRI: 0-24, 24-48, 48-72, and >72 h. Kruskal-Wallis, ANOVA, Chi-square, and Fisher's exact tests were used to reveal differences among the groups within clinical and imaging parameters; statistical power was calculated retrospectively for each comparison. Results: The Kruskal-Wallis ANOVA with Conover post hoc analysis showed significant (p = 0.01; 1-β > 0.9) median TMB number differences in the subacute period: 0-24 h = 4.00 (n = 11); 24-48 h = 1 (n = 14); 48-72 h = 1 (n = 11); and 72 h ≤ 7.5 (n = 10). Neither clinical parameters nor FLAIR lesions depicted significant differences among the groups. Conclusion: Our results demonstrate that TMBs on SWI MRI may temporarily become less detectable at 24-72 h following TBI. LA - English DB - MTMT ER - TY - CHAP AU - Shenker, Benjámin AU - Tóth, Luca AU - Maróti, Péter AU - Hrivnák, Gergely AU - Cserháti, Péter ED - Burger, Helena ED - Fazekas, Gábor ED - Vidmar, Gaj TI - First impressions with lower extremity exoskeleton during rehabilitation of spinal cord injured patients T2 - Congress of European Forum for Research in Rehabilitation PB - University Rehabilitation Institute Republic of Slovenia CY - Ljubljana SN - 9789617043068 PY - 2021 SP - 58 EP - 58 PG - 1 UR - https://m2.mtmt.hu/api/publication/32256992 ID - 32256992 LA - English DB - MTMT ER - TY - JOUR AU - Shenker, Benjámin AU - Tóth, Luca AU - Maróti, Péter AU - Büki, András AU - Fehér, Melinda AU - Klauber, András AU - Révay, Edit AU - Erdősi, Petra AU - Farkasinszky, Diána Edina AU - Nagy, Nikolett AU - Varga, Edina AU - Szabó-Szemenyei, Eszter AU - Vadai, Kitti AU - Papp, Leila AU - Hrivnák, Gergely AU - Cserháti, Péter TI - Alsó végtagi exoskeleton segítségével történő rehabilitációs tevékenység kezdeti tapasztalatai JF - IDŐSGYÓGYÁSZAT J2 - IDŐSGYÓGYÁSZAT VL - 6 PY - 2021 IS - 1-2 SP - 15 EP - 20 PG - 6 SN - 2498-8057 UR - https://m2.mtmt.hu/api/publication/32226057 ID - 32226057 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Tóth, Luca AU - Czigler, András AU - Horváth, Péter AU - Szarka, Nikolett AU - Környei, Bálint Soma AU - Tóth, Arnold AU - Schwarcz, Attila AU - Ungvári, Zoltán István AU - Büki, András AU - Tóth, Péter József TI - The effect of mild traumatic brain injury on cerebral microbleeds in aging JF - FRONTIERS IN AGING NEUROSCIENCE J2 - FRONT AGING NEUROSCI VL - 13 PY - 2021 PG - 7 SN - 1663-4365 DO - 10.3389/fnagi.2021.717391 UR - https://m2.mtmt.hu/api/publication/32172268 ID - 32172268 AB - A traumatic brain injury (TBI) induces the formation of cerebral microbleeds (CMBs), which are associated with cognitive impairments, psychiatric disorders, and gait dysfunctions in patients. Elderly people frequently suffer TBIs, especially mild brain trauma (mTBI). Interestingly, aging is also an independent risk factor for the development of CMBs. However, how TBI and aging may interact to promote the development of CMBs is not well established. In order to test the hypothesis that an mTBI exacerbates the development of CMBs in the elderly, we compared the number and cerebral distribution of CMBs and assessed them by analysing susceptibility weighted (SW) MRI in young (25 ± 10 years old, n = 18) and elder (72 ± 7 years old, n = 17) patients after an mTBI and in age-matched healthy subjects (young: 25 ± 6 years old, n = 20; aged: 68 ± 5 years old, n = 23). We found significantly more CMBs in elder patients after an mTBI compared with young patients; however, we did not observe a significant difference in the number of cerebral microhemorrhages between aged and aged patients with mTBI. The majority of CMBs were found supratentorially (lobar and basal ganglion). The lobar distribution of supratentorial CMBs showed that aging enhances the formation of parietal and occipital CMBs after mTBIs. This suggests that aging and mTBIs do not synergize in the induction of the development of CMBs, and that the different distribution of mTBI-induced CMBs in aged patients may lead to specific age-related clinical characteristics of mTBIs. LA - English DB - MTMT ER -