@article{MTMT:34687262, title = {Preparation, characterization and in vitro evaluation of the antimicrobial and antitumor activity of MnOx nanoparticles}, url = {https://m2.mtmt.hu/api/publication/34687262}, author = {Rónavári, Andrea and Ochirkhuyag, Altantuya and Igaz, Nóra and Szerencsés, Bettina and Ballai, Gergő and Huliák, Ildikó and Bocz, Csenge and Kovács, Ákos and Pfeiffer, Ilona and Csontné Kiricsi, Mónika and Kónya, Zoltán}, doi = {10.1016/j.colsurfa.2024.133528}, journal-iso = {COLLOID SURFACE A}, journal = {COLLOIDS AND SURFACES A : PHYSICOCHEMICAL AND ENGINEERING ASPECTS}, volume = {688}, unique-id = {34687262}, issn = {0927-7757}, year = {2024}, eissn = {1873-4359}, orcid-numbers = {Rónavári, Andrea/0000-0001-7054-0975; Ochirkhuyag, Altantuya/0000-0001-6495-7360; Igaz, Nóra/0000-0003-1580-4397; Pfeiffer, Ilona/0000-0003-0680-7596; Csontné Kiricsi, Mónika/0000-0002-8416-2052; Kónya, Zoltán/0000-0002-9406-8596} } @article{MTMT:33538161, title = {Semi-Synthetic Ecdysteroid 6-Oxime Derivatives of 20-Hydroxyecdysone Possess Anti-Cryptococcal Activity}, url = {https://m2.mtmt.hu/api/publication/33538161}, author = {Szerencsés, Bettina and Vörös, Mónika and Bagi, Kristóf and Háznagy, Márton Benedek and Hunyadi, Attila and Vágvölgyi, Csaba and Pfeiffer, Ilona and Vágvölgyi, Máté}, doi = {10.3390/microbiolres13040071}, journal-iso = {MICROBIOL RES-ITALY}, journal = {MICROBIOLOGY RESEARCH}, volume = {13}, unique-id = {33538161}, issn = {2036-7473}, abstract = {Cryptococcosis, a life-threatening fungal infection, frequently occurs in patients suffering from AIDS. The treatment of the disease is hampered by the limited number of the effective drugs and the increasing resistance; therefore, to find new active substances is needed. As meningitis is the most serious infection affecting the AIDS patients, effective drugs have to be capable of entering to the central nervous system. Ecdysteroids are natural bioactive molecules with considerable anabolic activity and without toxic side effects on humans. The aim of this work was to study the anti-cryptococcal activity of a natural ecdysteroid, 20E, and its three semi-synthetic derivatives obtained by structural modification of the original molecule. We established the minimum inhibitory concentration of the compounds with microdilution method and demonstrated their fungicidal activity by flow cytometry and cultivation of the drug-treated cells. The interaction of the compounds with each other and efflux transporter inhibitors was assessed by checkerboard titration method. Two derivatives, 20E-EOx and 20E-ZOx, inhibited the growth of Cryptococcus neoformans with minimum inhibitory concentration 2 mg/mL and 1 mg/mL, respectively; both compounds possess fungicidal effect. A combination of the ecdysteroids with each other and verapamil resulted in additive interaction. This study confirmed that structural modification of an originally non-antimicrobial molecule can enhance its effectiveness.}, year = {2022}, eissn = {2036-7481}, pages = {985-994}, orcid-numbers = {Vörös, Mónika/0000-0003-4236-3929; Hunyadi, Attila/0000-0003-0074-3472; Vágvölgyi, Csaba/0000-0003-0009-7773; Pfeiffer, Ilona/0000-0003-0680-7596; Vágvölgyi, Máté/0000-0002-2233-9422} } @article{MTMT:32131688, title = {Polyvinyl-Pyrrolidone-Coated Silver Nanoparticles—The Colloidal, Chemical, and Biological Consequences of Steric Stabilization under Biorelevant Conditions}, url = {https://m2.mtmt.hu/api/publication/32131688}, author = {Rónavári, Andrea and Bélteky, Péter and Boka, Eszter and Zakupszky, Dalma and Igaz, Nóra and Szerencsés, Bettina and Pfeiffer, Ilona and Kónya, Zoltán and Csontné Kiricsi, Mónika}, doi = {10.3390/ijms22168673}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {22}, unique-id = {32131688}, issn = {1661-6596}, year = {2021}, eissn = {1422-0067}, orcid-numbers = {Rónavári, Andrea/0000-0001-7054-0975; Igaz, Nóra/0000-0003-1580-4397; Pfeiffer, Ilona/0000-0003-0680-7596; Kónya, Zoltán/0000-0002-9406-8596; Csontné Kiricsi, Mónika/0000-0002-8416-2052} } @article{MTMT:31982606, title = {Are Smaller Nanoparticles Always Better? Understanding the Biological Effect of Size-Dependent Silver Nanoparticle Aggregation Under Biorelevant Conditions}, url = {https://m2.mtmt.hu/api/publication/31982606}, author = {Bélteky, Péter and Rónavári, Andrea and Zakupszky, Dalma and Boka, Eszter and Igaz, Nóra and Szerencsés, Bettina and Pfeiffer, Ilona and Vágvölgyi, Csaba and Csontné Kiricsi, Mónika and Kónya, Zoltán}, doi = {10.2147/IJN.S304138}, journal-iso = {INT J NANOMED}, journal = {INTERNATIONAL JOURNAL OF NANOMEDICINE}, volume = {16}, unique-id = {31982606}, issn = {1176-9114}, year = {2021}, eissn = {1178-2013}, pages = {3021-3040}, orcid-numbers = {Rónavári, Andrea/0000-0001-7054-0975; Igaz, Nóra/0000-0003-1580-4397; Pfeiffer, Ilona/0000-0003-0680-7596; Vágvölgyi, Csaba/0000-0003-0009-7773; Csontné Kiricsi, Mónika/0000-0002-8416-2052; Kónya, Zoltán/0000-0002-9406-8596} } @article{MTMT:31953278, title = {Symbiotic NCR Peptide Fragments Affect the Viability, Morphology and Biofilm Formation of Candida Species}, url = {https://m2.mtmt.hu/api/publication/31953278}, author = {Szerencsés, Bettina and Gácser, Attila and Endre, Gabriella and Racskóné Domonkos, Ildikó and Tiricz, Hilda and Vágvölgyi, Csaba and Szolomájer, János and Howan, Dian Herlinda Octorina and Tóth, Gábor and Pfeiffer, Ilona and Kondorosi, Éva}, doi = {10.3390/ijms22073666}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {22}, unique-id = {31953278}, issn = {1661-6596}, year = {2021}, eissn = {1422-0067}, orcid-numbers = {Gácser, Attila/0000-0003-2939-9580; Vágvölgyi, Csaba/0000-0003-0009-7773; Szolomájer, János/0000-0003-1458-6156; Tóth, Gábor/0000-0002-3604-4385; Pfeiffer, Ilona/0000-0003-0680-7596; Kondorosi, Éva/0000-0002-4065-8515} } @article{MTMT:31852610, title = {Green Silver and Gold Nanoparticles: Biological Synthesis Approaches and Potentials for Biomedical Applications}, url = {https://m2.mtmt.hu/api/publication/31852610}, author = {Rónavári, Andrea and Igaz, Nóra and Adamecz, Dóra Izabella and Szerencsés, Bettina and Molnár, Csaba and Kónya, Zoltán and Pfeiffer, Ilona and Csontné Kiricsi, Mónika}, doi = {10.3390/molecules26040844}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {26}, unique-id = {31852610}, issn = {1420-3049}, year = {2021}, eissn = {1420-3049}, orcid-numbers = {Rónavári, Andrea/0000-0001-7054-0975; Igaz, Nóra/0000-0003-1580-4397; Adamecz, Dóra Izabella/0000-0002-1883-9600; Molnár, Csaba/0000-0002-6124-1209; Kónya, Zoltán/0000-0002-9406-8596; Pfeiffer, Ilona/0000-0003-0680-7596; Csontné Kiricsi, Mónika/0000-0002-8416-2052} } @{MTMT:31821390, title = {The effect of biological conditions on silver nanoparticle toxicity: just how important nanoparticle aggregation really is?}, url = {https://m2.mtmt.hu/api/publication/31821390}, author = {Bélteky, Péter and Rónavári, Andrea and Eszter, Boka and Dalma, Zakupszky and Igaz, Nóra and Szerencsés, Bettina and Tóth, Ildikó and Pfeiffer, Ilona and Csontné Kiricsi, Mónika and Zoltán, Kónya}, booktitle = {IX. INTERDISZCIPLINÁRIS DOKTORANDUSZ KONFERENCIA 2020 ABSZTRAKTKÖTET}, unique-id = {31821390}, year = {2020}, pages = {311-311}, orcid-numbers = {Rónavári, Andrea/0000-0001-7054-0975; Igaz, Nóra/0000-0003-1580-4397; Tóth, Ildikó/0000-0002-4937-0526; Pfeiffer, Ilona/0000-0003-0680-7596; Csontné Kiricsi, Mónika/0000-0002-8416-2052; Zoltán, Kónya/0000-0002-9406-8596} } @article{MTMT:31353819, title = {Size-dependent activity of silver nanoparticles on the morphological switch and biofilm formation of opportunistic pathogenic yeasts}, url = {https://m2.mtmt.hu/api/publication/31353819}, author = {Szerencsés, Bettina and Igaz, Nóra and Tóbiás, Ákos and Prucsi, Zsombor and Rónavári, Andrea and Bélteky, Péter and Madarász, Dániel and Papp, Csaba Gergő and Makra, Ildikó and Vágvölgyi, Csaba and Kónya, Zoltán and Pfeiffer, Ilona and Csontné Kiricsi, Mónika}, doi = {10.1186/s12866-020-01858-9}, journal-iso = {BMC MICROBIOL}, journal = {BMC MICROBIOLOGY}, volume = {20}, unique-id = {31353819}, issn = {1471-2180}, year = {2020}, eissn = {1471-2180}, orcid-numbers = {Igaz, Nóra/0000-0003-1580-4397; Rónavári, Andrea/0000-0001-7054-0975; Papp, Csaba Gergő/0000-0003-4450-0667; Vágvölgyi, Csaba/0000-0003-0009-7773; Kónya, Zoltán/0000-0002-9406-8596; Pfeiffer, Ilona/0000-0003-0680-7596; Csontné Kiricsi, Mónika/0000-0002-8416-2052} } @article{MTMT:31364282, title = {In vitro interactions of amphotericin B and non-antifungal compounds against opportunistic human pathogen Cryptococcus neoformans}, url = {https://m2.mtmt.hu/api/publication/31364282}, author = {Szerencsés, Bettina and Mülbacher, Anna and Vágvölgyi, Csaba and Pfeiffer, Ilona}, doi = {10.14232/abs.2019.2.181-184}, journal-iso = {ACTA BIOL SZEGED}, journal = {ACTA BIOLOGICA SZEGEDIENSIS}, volume = {63}, unique-id = {31364282}, issn = {1588-385X}, year = {2019}, eissn = {1588-4082}, pages = {181-184}, orcid-numbers = {Vágvölgyi, Csaba/0000-0003-0009-7773; Pfeiffer, Ilona/0000-0003-0680-7596} } @article{MTMT:30398793, title = {Silver nanoparticles: aggregation behavior in biorelevant conditions and its impact on biological activity}, url = {https://m2.mtmt.hu/api/publication/30398793}, author = {Bélteky, Péter and Rónavári, Andrea and Igaz, Nóra and Szerencsés, Bettina and Tóth, Ildikó and Pfeiffer, Ilona and Csontné Kiricsi, Mónika and Kónya, Zoltán}, doi = {10.2147/IJN.S185965}, journal-iso = {INT J NANOMED}, journal = {INTERNATIONAL JOURNAL OF NANOMEDICINE}, volume = {14}, unique-id = {30398793}, issn = {1176-9114}, abstract = {Purpose: The biomedical applications of silver nanoparticles (AgNPs) are heavily investigated due to their cytotoxic and antimicrobial properties. However, the scientific literature is lacking in data on the aggregation behavior of nanoparticles, especially regarding its impact on biological activity. Therefore, to assess the potential of AgNPs in therapeutic applications, two different AgNP samples were compared under biorelevant conditions.}, year = {2019}, eissn = {1178-2013}, pages = {667-687}, orcid-numbers = {Rónavári, Andrea/0000-0001-7054-0975; Igaz, Nóra/0000-0003-1580-4397; Tóth, Ildikó/0000-0002-4937-0526; Pfeiffer, Ilona/0000-0003-0680-7596; Csontné Kiricsi, Mónika/0000-0002-8416-2052; Kónya, Zoltán/0000-0002-9406-8596} }