@misc{MTMT:34498239, title = {Multirezisztens kórokozók szűrése egy egyetemi kórház központi intenzív osztályán}, url = {https://m2.mtmt.hu/api/publication/34498239}, author = {Schneider-Patkó, Brigitta and Kovács, Krisztina and Zsoldiné Urbán, Edit and Lutz, Zsolt and Nyul, Adrienn and Fenyvesi, Hajnalka and Csontos, Csaba and Rauth, Erika and Sonnevend, Ágnes}, unique-id = {34498239}, year = {2023}, orcid-numbers = {Zsoldiné Urbán, Edit/0000-0002-9602-7552} } @misc{MTMT:34498236, title = {NDM-5 termelő Escherichia coli ST361 megjelenése és terjedése Baranya vármegyében.}, url = {https://m2.mtmt.hu/api/publication/34498236}, author = {Meszéna, Réka and Schneider-Patkó, Brigitta and Halda-Kiss, Bernadett and Kovács, Krisztina and Zsoldiné Urbán, Edit and Lutz, Zsolt and Nyul, Adrienn and Fenyvesi, Hajnalka and Urbán, Péter and Gyenesei, Attila and Tóth, Ákos and Pál, Tibor and Sonnevend, Ágnes}, unique-id = {34498236}, year = {2023}, orcid-numbers = {Zsoldiné Urbán, Edit/0000-0002-9602-7552} } @CONFERENCE{MTMT:33118493, title = {Anaerob baktériumok által okozott véráramfertőzések epidemiológiája egy egyetemi központban: 5-éves retrospektív, megfigyeléses vizsgálat}, url = {https://m2.mtmt.hu/api/publication/33118493}, author = {Kovács, Krisztina and Nyul, Adrienn and Lutz, Zsolt and Mestyán, Gyula and Gajdács, Márió and Zsoldiné Urbán, Edit and Sonnevend, Ágnes}, booktitle = {Szegedi Fogorvosnapok 2022. Szegedi Fogorvos Találkozó és Tudományos Konferencia, Magyar Gyermekfogászati és Fogszabályozási Társaság IX. Tóth Pál Vándorgyűlés}, unique-id = {33118493}, year = {2022}, pages = {40-41}, orcid-numbers = {Gajdács, Márió/0000-0003-1270-0365; Zsoldiné Urbán, Edit/0000-0002-9602-7552} } @article{MTMT:33116337, title = {Incidence and Clinical Characteristics of Anaerobic Bacteremia at a University Hospital in Hungary: A 5-Year Retrospective Observational Study}, url = {https://m2.mtmt.hu/api/publication/33116337}, author = {Kovács, Krisztina and Nyul, Adrienn and Lutz, Zsolt and Mestyán, Gyula and Gajdács, Márió and Zsoldiné Urbán, Edit and Sonnevend, Ágnes}, doi = {10.3390/antibiotics11101326}, journal-iso = {ANTIBIOTICS-BASEL}, journal = {ANTIBIOTICS}, volume = {11}, unique-id = {33116337}, year = {2022}, eissn = {2079-6382}, orcid-numbers = {Gajdács, Márió/0000-0003-1270-0365; Zsoldiné Urbán, Edit/0000-0002-9602-7552} } @article{MTMT:31926267, title = {Isolation and Characterization of a Novel Lytic Bacteriophage against the K2 Capsule-Expressing Hypervirulent Klebsiella pneumoniae Strain 52145, and Identification of Its Functional Depolymerase}, url = {https://m2.mtmt.hu/api/publication/31926267}, author = {Pertics, Botond Zsombor and Cox, Alysia and Nyul, Adrienn and Szamek, Nóra and Kovács, Tamás and Schneider, György}, doi = {10.3390/microorganisms9030650}, journal-iso = {MICROORGANISMS}, journal = {MICROORGANISMS}, volume = {9}, unique-id = {31926267}, issn = {2076-2607}, abstract = {Klebsiella pneumoniae is among the leading bacteria that cause nosocomial infections. The capsule of this Gram-negative bacterium is a dominant virulence factor, with a prominent role in defense and biofilm formation. Bacteriophages, which are specific for one bacterial strain and its capsule type, can evoke the lysis of bacterial cells, aided by polysaccharide depolymerase enzymes. In this study, we isolated and characterized a bacteriophage against the nosocomial K. pneumoniae 52145 strain with K2 capsular serotype. The phage showed a narrow host range and stable lytic activity, even when exposed to different temperatures or detergents. Preventive effect of the phage in a nasal colonization model was investigated in vivo. Phlyogenetic analysis showed that the newly isolated Klebsiella phage B1 belongs to the Webervirus genus in Drexlerviridae family. We identified the location of the capsule depolymerase gene of the new phage, which was amplified, cloned, expressed, and purified. The efficacy of the recombinant B1dep depolymerase was tested by spotting on K. pneumoniae strains and it was confirmed that the extract lowers the thickness of the bacterium lawn as it degrades the protective capsule on bacterial cells. As K. pneumoniae strains possessing the K2 serotype have epidemiological importance, the B1 phage and its depolymerase are promising candidates for use as possible antimicrobial agents.}, keywords = {bacteriophage; klebsiella pneumoniae; K2 serotype; tail fibers; capsule depolymerase}, year = {2021}, eissn = {2076-2607}, orcid-numbers = {Pertics, Botond Zsombor/0000-0002-1734-1632} } @article{MTMT:31408959, title = {Streptococcus suis: An Underestimated Emerging Pathogen in Hungary?}, url = {https://m2.mtmt.hu/api/publication/31408959}, author = {Gajdács, Márió and Németh, Anita and Knausz, Márta and Barrak, Ibrahim Ádám and Stájer, Anette and Mestyán, Gyula and Melegh, Szilvia Zsóka and Nyul, Adrienn and Tóth, Ákos and Ágoston, Zsuzsanna and Zsoldiné Urbán, Edit}, doi = {10.3390/microorganisms8091292}, journal-iso = {MICROORGANISMS}, journal = {MICROORGANISMS}, volume = {8}, unique-id = {31408959}, issn = {2076-2607}, year = {2020}, eissn = {2076-2607}, orcid-numbers = {Gajdács, Márió/0000-0003-1270-0365; Barrak, Ibrahim Ádám/0000-0001-8808-1762; Stájer, Anette/0000-0003-4158-173X; Zsoldiné Urbán, Edit/0000-0002-9602-7552} } @article{MTMT:30637910, title = {Kórokozóspektrum egy hematológiai osztályon}, url = {https://m2.mtmt.hu/api/publication/30637910}, author = {Sipos, Dávid and Nyul, Adrienn and Kovács, Krisztina and Alizadeh, Hussain and Péterfi, Zoltán}, doi = {10.1556/2068.2019.52.1.11}, journal-iso = {HEMATOLÓGIA-TRANSZFUZIOLÓGIA}, journal = {HEMATOLÓGIA-TRANSZFUZIOLÓGIA}, volume = {52}, unique-id = {30637910}, issn = {1786-5913}, year = {2019}, pages = {57-61}, orcid-numbers = {Péterfi, Zoltán/0000-0001-9658-153X} } @article{MTMT:3371681, title = {Dissemination of VanA-Type Enterococcus faecium Isolates in Hungary.}, url = {https://m2.mtmt.hu/api/publication/3371681}, author = {Melegh, Szilvia Zsóka and Nyul, Adrienn and Kovács, Krisztina and Kovács, Tamás and Ghidán, Ágoston and Dombrádi, Zsuzsanna Rita and Szabó, Judit and Berta, B and Lesinszki, V and Paszti, J and Tóth, Ákos and Mestyán, Gyula}, doi = {10.1089/mdr.2017.0296}, journal-iso = {MICROB DRUG RESIST}, journal = {MICROBIAL DRUG RESISTANCE}, volume = {24}, unique-id = {3371681}, issn = {1076-6294}, abstract = {Although vanA carrying Enterococcus faecium human clinical isolates have been rarely found in Hungary before 2012, they have been detected in continuously increasing numbers since then. To identify factors associated with their dissemination, we investigated the clonal relatedness and plasmids of 30 vanA carrying E. faecium isolates originating from different Hungarian healthcare institutions from 2012 to 2014. Molecular typing of the isolates (n = 30) was performed with pulsed-field gel electrophoresis (PFGE), multilocus sequence typing, Tn1546 polymerase chain reaction mapping, plasmid restriction fragment length polymorphism analysis, and sequencing. A single Tn1546 variant was detected in all of the isolates. It harbored IS1251 in the vanS-vanH intergenic region, had an entire deletion of the transposase gene and a partial deletion of the resolvase gene, and was located on a pRUM-like plasmid. Based on PFGE, the isolates could be grouped into 13 pulsotypes. Representative strains of these pulsotypes belonged to ST17, ST18, ST80, ST117, and ST203, which are known to be part of the hospital-adapted clades. The increase in the number of vanA carrying E. faecium clinical isolates in Hungary could be explained by the dissemination of pRUM-like vancomycin resistance plasmids in hospital-adapted clonal lineages.}, keywords = {Molecular Epidemiology; Vancomycin Resistance; Enterococcus faecium}, year = {2018}, eissn = {1931-8448}, pages = {1376-1390}, orcid-numbers = {Ghidán, Ágoston/0000-0002-2397-1809} } @article{MTMT:3097563, title = {Emergence and interhospital spread of OXA-48-producing Klebsiella pneumoniae ST395 clone in Western Hungary.}, url = {https://m2.mtmt.hu/api/publication/3097563}, author = {Kovács, Krisztina and Nyul, Adrienn and Mestyan, G and Melegh, Szilvia Zsóka and Fenyvesi, H and Jakab, G and Szabo, H and Janvari, L and Damjanova, I and Tóth, Ákos}, doi = {10.1080/23744235.2016.1207252}, journal-iso = {INFECT DIS-NOR}, journal = {INFECTIOUS DISEASES}, volume = {49}, unique-id = {3097563}, issn = {2374-4235}, year = {2017}, eissn = {2374-4243}, pages = {231-233} } @article{MTMT:2540197, title = {Emergence of VIM-4 metallo-β-lactamase-producing Klebsiella pneumoniae ST15 clone in the Clinical Centre University of Pécs, Hungary}, url = {https://m2.mtmt.hu/api/publication/2540197}, author = {Melegh, Szilvia Zsóka and Kovács, Krisztina and Gám, T and Nyul, Adrienn and Patkó, B and Tóth, Ákos and Damjanova, I and Mestyán, G}, doi = {10.1111/1469-0691.12293}, journal-iso = {CLIN MICROBIOL INFEC}, journal = {CLINICAL MICROBIOLOGY AND INFECTION}, volume = {20}, unique-id = {2540197}, issn = {1198-743X}, keywords = {Humans; Hungary/epidemiology; polymerase chain reaction; Microbial Sensitivity Tests; Anti-Bacterial Agents/pharmacology; molecular typing; Klebsiella Infections/*microbiology; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Drug Resistance, Multiple, Bacterial; Hospitals, University; beta-Lactamases/*genetics/*metabolism; Klebsiella pneumoniae/classification/*enzymology/*isolation & purification; Carbapenems/pharmacology}, year = {2014}, eissn = {1469-0691}, pages = {O27-O29} }