@article{MTMT:31290812,
	title = {The effect of the preimplantation factor on the cardiac expression of miR-21 in radiation-induced heart disease},
	url = {https://m2.mtmt.hu/api/publication/31290812},
	author = {Kovács, Mónika Gabriella and Kiscsatári, Laura and Varga, Zoltán and Kővári, Bence and Fábián, Gabriella and Cserni, Gábor and Thum, Thomas and Csont, Tamás Bálint and Bátkai, Sándor and Barnea, Eytan and Kahán, Zsuzsanna and Sárközy, Márta},
	journal-iso = {ACTA PHYSIOL},
	journal = {ACTA PHYSIOLOGICA},
	volume = {227},
	unique-id = {31290812},
	issn = {1748-1708},
	year = {2019},
	eissn = {1748-1716},
	pages = {166-167},
	orcid-numbers = {Kovács, Mónika Gabriella/0000-0002-5756-4662; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Fábián, Gabriella/0000-0002-2323-4948; Cserni, Gábor/0000-0003-1344-7744; Csont, Tamás Bálint/0000-0001-5792-2768; Kahán, Zsuzsanna/0000-0002-5021-8775; Sárközy, Márta/0000-0002-5929-2146}
}

@article{MTMT:31290227,
	title = {A preimplantációs faktor hatása a miR-21 kardiális expressziójára radiogén szívkárosodásban [The effect of preimplantation factor on the cardiac expression of miR-21 in radiation-induced heart disease]},
	url = {https://m2.mtmt.hu/api/publication/31290227},
	author = {Kovács, Mónika Gabriella and Kiscsatári, Laura and Varga, Zoltán and Kővári, Bence and Fábián, Gabriella and Cserni, Gábor and Thomas, Thum and Csont, Tamás Bálint and Bátkai, Sándor and Eytan, Barnea and Kahán, Zsuzsanna and Sárközy, Márta},
	journal-iso = {CARDIOL HUNG},
	journal = {CARDIOLOGIA HUNGARICA},
	volume = {49},
	unique-id = {31290227},
	issn = {0133-5596},
	year = {2019},
	eissn = {1588-0230},
	pages = {B29-B30},
	orcid-numbers = {Kovács, Mónika Gabriella/0000-0002-5756-4662; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Fábián, Gabriella/0000-0002-2323-4948; Cserni, Gábor/0000-0003-1344-7744; Csont, Tamás Bálint/0000-0001-5792-2768; Kahán, Zsuzsanna/0000-0002-5021-8775; Sárközy, Márta/0000-0002-5929-2146}
}

@{MTMT:31289421,
	title = {A preimplantációs faktor hatása a miR-21 kardiális expressziójára radiogén szívkárosodásban},
	url = {https://m2.mtmt.hu/api/publication/31289421},
	author = {Kovács, Mónika Gabriella and Kiscsatári, Laura and Varga, Zoltán and Kővári, Bence and Fábián, Gabriella and Cserni, Gábor and Thomas, Thum and Csont, Tamás Bálint and Bátkai, Sándor and Eytan, Barnea and Kahán, Zsuzsanna and Sárközy, Márta},
	booktitle = {FAMÉ 2019 Magyar Kísérletes és Klinikai Farmakológiai Társaság; Magyar Anatómus Társaság; Magyar Mikrocirkulációs és Vaszkuláris Biológiai Társaság; Magyar Élettani Társaság},
	unique-id = {31289421},
	year = {2019},
	pages = {72-72},
	orcid-numbers = {Kovács, Mónika Gabriella/0000-0002-5756-4662; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Fábián, Gabriella/0000-0002-2323-4948; Cserni, Gábor/0000-0003-1344-7744; Csont, Tamás Bálint/0000-0001-5792-2768; Kahán, Zsuzsanna/0000-0002-5021-8775; Sárközy, Márta/0000-0002-5929-2146}
}

@article{MTMT:30755535,
	title = {Selective Heart Irradiation Induces Cardiac Overexpression of the Pro-hypertrophic miR-212},
	url = {https://m2.mtmt.hu/api/publication/30755535},
	author = {Sárközy, Márta and Molnár-Gáspár, Renáta and Zvara, Ágnes and Kiscsatári, Laura and Varga, Zoltán and Kővári, Bence and Kovács, Mónika Gabriella and Szűcs, Gergő and Fábián, Gabriella and Diószegi, Petra and Cserni, Gábor and Puskás, László and Thum, Thomas and Kahán, Zsuzsanna and Csont, Tamás Bálint and Batkai, Sandor},
	doi = {10.3389/fonc.2019.00598},
	journal-iso = {FRONT ONCOL},
	journal = {FRONTIERS IN ONCOLOGY},
	volume = {9},
	unique-id = {30755535},
	issn = {2234-943X},
	abstract = {Background: A deleterious, late-onset side effect of thoracic radiotherapy is the development of radiation-induced heart disease (RIHD). It covers a spectrum of cardiac pathology including also heart failure with preserved ejection fraction (HFpEF) characterized by left ventricular hypertrophy (LVH) and diastolic dysfunction. MicroRNA-212 (miR-212) is a crucial regulator of pathologic LVH via FOXO3-mediated pathways in pressure-overload-induced heart failure. We aimed to investigate whether miR-212 and its selected hypertrophy-associated targets play a role in the development of RIHD.Methods: RIHD was induced by selective heart irradiation (50Gy) in a clinically relevant rat model. One, three, and nineteen weeks after selective heart irradiation, transthoracic echocardiography was performed to monitor cardiac morphology and function. Cardiomyocyte hypertrophy and fibrosis were assessed by histology at week 19. qRT-PCR was performed to measure the gene expression changes of miR-212 and forkhead box O3 (FOXO3) in all follow-up time points. The cardiac transcript level of other selected hypertrophy-associated targets of miR-212 including extracellular signal-regulated kinase 2 (ERK2), myocyte enhancer factor 2a (MEF2a), AMP-activated protein kinase, (AMPK), heat shock protein 40 (HSP40), sirtuin 1, (SIRT1), calcineurin A-alpha and phosphatase and tensin homolog (PTEN) were also measured at week 19. Cardiac expression of FOXO3 and phospho-FOXO3 were investigated at the protein level by Western blot at week 19.Results: In RIHD, diastolic dysfunction was present at every time point. Septal hypertrophy developed at week 3 and a marked LVH with interstitial fibrosis developed at week 19 in the irradiated hearts. In RIHD, cardiac miR-212 was overexpressed at week 3 and 19, and FOXO3 was repressed at the mRNA level only at week 19. In contrast, the total FOXO3 protein level failed to decrease in response to heart irradiation at week 19. Other selected hypertrophy-associated target genes failed to change at the mRNA level in RIHD at week 19.Conclusions: LVH in RIHD was associated with cardiac overexpression of miR-212. However, miR-212 seems to play a role in the development of LVH via FOXO3-independent mechanisms in RIHD. As a central regulator of pathologic remodeling, miR-212 might become a novel target for RIHD-induced LVH and heart failure.},
	keywords = {left ventricular hypertrophy; Heart failure with preserved ejection fraction (HFpEF); FOXO3; thoracic irradiation; miRNA-212},
	year = {2019},
	eissn = {2234-943X},
	orcid-numbers = {Sárközy, Márta/0000-0002-5929-2146; Molnár-Gáspár, Renáta/0000-0001-9673-4532; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Kovács, Mónika Gabriella/0000-0002-5756-4662; Szűcs, Gergő/0000-0003-1874-2718; Fábián, Gabriella/0000-0002-2323-4948; Diószegi, Petra/0000-0001-8109-2266; Cserni, Gábor/0000-0003-1344-7744; Kahán, Zsuzsanna/0000-0002-5021-8775; Csont, Tamás Bálint/0000-0001-5792-2768}
}

@CONFERENCE{MTMT:31289399,
	title = {Selective heart irradiation induces cardiac overexpression of the pro-hypertrophic miR-212},
	url = {https://m2.mtmt.hu/api/publication/31289399},
	author = {Sárközy, Márta and Molnár-Gáspár, Renáta and Ágnes, Zvara and Kiscsatári, Laura and Varga, Zoltán and Kővári, Bence and Kovács, Mónika Gabriella and Szűcs, Gergő and Fábián, Gabriella and Cserni, Gábor and László, G. Puskás and Thomas, Thum and Kahán, Zsuzsanna and Csont, Tamás Bálint and Sándor, Bátkai},
	booktitle = {The 44th Annual Meeting of the European Radiation Research Society: Program and Abstract Book},
	unique-id = {31289399},
	abstract = {Poster session: Pre- and clinical research supporting human radiotherapy},
	year = {2018},
	pages = {160-160},
	orcid-numbers = {Sárközy, Márta/0000-0002-5929-2146; Molnár-Gáspár, Renáta/0000-0001-9673-4532; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Kovács, Mónika Gabriella/0000-0002-5756-4662; Szűcs, Gergő/0000-0003-1874-2718; Fábián, Gabriella/0000-0002-2323-4948; Cserni, Gábor/0000-0003-1344-7744; Kahán, Zsuzsanna/0000-0002-5021-8775; Csont, Tamás Bálint/0000-0001-5792-2768}
}

@CONFERENCE{MTMT:3399366,
	title = {A hipertrófiás miR-212/132 klaszter kardiális expressziója megemelkedik radiogén szívkárosodásban},
	url = {https://m2.mtmt.hu/api/publication/3399366},
	author = {Sárközy, Márta and Molnár-Gáspár, Renáta and Zvara, Ágnes and Kiscsatári, Laura and Varga, Zoltán and Kővári, Bence and Kovács, Mónika Gabriella and Szűcs, Gergő and Diószegi, Petra and Fábián, Gabriella and Cserni, Gábor and Puskás, G László and Thomas, Thum and Kahán, Zsuzsanna and Csont, Tamás Bálint and Bátkai, Sándor},
	booktitle = {Magyar Élettani Társaság 2018. évi Vándorgyűlése : előadás és poszter absztraktok},
	unique-id = {3399366},
	year = {2018},
	pages = {83-83},
	orcid-numbers = {Sárközy, Márta/0000-0002-5929-2146; Molnár-Gáspár, Renáta/0000-0001-9673-4532; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Kovács, Mónika Gabriella/0000-0002-5756-4662; Szűcs, Gergő/0000-0003-1874-2718; Diószegi, Petra/0000-0001-8109-2266; Fábián, Gabriella/0000-0002-2323-4948; Cserni, Gábor/0000-0003-1344-7744; Kahán, Zsuzsanna/0000-0002-5021-8775; Csont, Tamás Bálint/0000-0001-5792-2768}
}

@article{MTMT:3377886,
	title = {Selective heart irradiation induces left ventricular hypertrophy and diastolic dysfunction with overexpression of the miR-212/132 cluster},
	url = {https://m2.mtmt.hu/api/publication/3377886},
	author = {Sárközy, Márta and Molnár-Gáspár, Renáta and Zvara, Ágnes and Kiscsatári, Laura and Varga, Zoltán and Kővári, Bence and Kovács, Mónika Gabriella and Szűcs, Gergő and Fábián, Gabriella and Cserni, Gábor and László, G Puskás and Thomas, Thum and Kahán, Zsuzsanna and Csont, Tamás Bálint and Sándor, Bátkai},
	journal-iso = {EUR J HEART FAIL},
	journal = {EUROPEAN JOURNAL OF HEART FAILURE},
	volume = {20},
	unique-id = {3377886},
	issn = {1388-9842},
	year = {2018},
	eissn = {1879-0844},
	pages = {334-334},
	orcid-numbers = {Sárközy, Márta/0000-0002-5929-2146; Molnár-Gáspár, Renáta/0000-0001-9673-4532; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Kovács, Mónika Gabriella/0000-0002-5756-4662; Szűcs, Gergő/0000-0003-1874-2718; Fábián, Gabriella/0000-0002-2323-4948; Cserni, Gábor/0000-0003-1344-7744; Kahán, Zsuzsanna/0000-0002-5021-8775; Csont, Tamás Bálint/0000-0001-5792-2768}
}

@article{MTMT:3370814,
	title = {A pro-hipertrófiás miR-212/132 klaszter kardiális expressziója megemelkedik radiogén szívkárosodásban [Selective heart irradiation induces cardiac over-expression of the pro-hypertropic miR-212/132 cluster]},
	url = {https://m2.mtmt.hu/api/publication/3370814},
	author = {Sárközy, Márta and Molnár-Gáspár, Renáta and Zvara, Ágnes and Kiscsatári, Laura and Varga, Zoltán and Kővári, Bence and Kovács, Mónika Gabriella and Szűcs, Gergő and Fábián, Gabriella and Cserni, Gábor and Puskás, G. László and Thum, Thomas and Kahán, Zsuzsanna and Csont, Tamás Bálint and Bátkai, Sándor},
	journal-iso = {CARDIOL HUNG},
	journal = {CARDIOLOGIA HUNGARICA},
	volume = {48},
	unique-id = {3370814},
	issn = {0133-5596},
	year = {2018},
	eissn = {1588-0230},
	pages = {C34-C35},
	orcid-numbers = {Sárközy, Márta/0000-0002-5929-2146; Molnár-Gáspár, Renáta/0000-0001-9673-4532; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Kovács, Mónika Gabriella/0000-0002-5756-4662; Szűcs, Gergő/0000-0003-1874-2718; Fábián, Gabriella/0000-0002-2323-4948; Cserni, Gábor/0000-0003-1344-7744; Kahán, Zsuzsanna/0000-0002-5021-8775; Csont, Tamás Bálint/0000-0001-5792-2768}
}

@article{MTMT:3247661,
	title = {A miR-212/132 cluster és a kalcineurin jelút szerepe a radiogén szívkárosodásban [The role of the miR-212/132 cluster and the calcineurin pathway in the development of radiation induced heart disease]},
	url = {https://m2.mtmt.hu/api/publication/3247661},
	author = {Sárközy, Márta and Kiscsatári, Laura and Molnár-Gáspár, Renáta and Varga, Zoltán and Kővári, Bence and Fábián, Gabriella and Cserni, Gábor and Thum, Thomas and Kahán, Zsuzsanna and Bátkai, Sándor and Csont, Tamás Bálint},
	journal-iso = {CARDIOL HUNG},
	journal = {CARDIOLOGIA HUNGARICA},
	volume = {47},
	unique-id = {3247661},
	issn = {0133-5596},
	year = {2017},
	eissn = {1588-0230},
	pages = {C44-C44},
	orcid-numbers = {Sárközy, Márta/0000-0002-5929-2146; Molnár-Gáspár, Renáta/0000-0001-9673-4532; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Fábián, Gabriella/0000-0002-2323-4948; Cserni, Gábor/0000-0003-1344-7744; Kahán, Zsuzsanna/0000-0002-5021-8775; Csont, Tamás Bálint/0000-0001-5792-2768}
}

@{MTMT:3247660,
	title = {The role of the miR-212/132 cluster in the development of radiation induced heart disease},
	url = {https://m2.mtmt.hu/api/publication/3247660},
	author = {Sárközy, Márta and Kiscsatári, Laura and Molnár-Gáspár, Renáta and Varga, Zoltán and Kővári, Bence and Fábián, Gabriella and Cserni, Gábor and Thomas, Thum and Kahán, Zsuzsanna and Sándor, Bátkai and Csont, Tamás Bálint},
	booktitle = {Hungarian Molecular Life Sciences 2017},
	unique-id = {3247660},
	year = {2017},
	pages = {222-222},
	orcid-numbers = {Sárközy, Márta/0000-0002-5929-2146; Molnár-Gáspár, Renáta/0000-0001-9673-4532; Varga, Zoltán/0000-0001-8537-6282; Kővári, Bence/0000-0002-4498-8781; Fábián, Gabriella/0000-0002-2323-4948; Cserni, Gábor/0000-0003-1344-7744; Kahán, Zsuzsanna/0000-0002-5021-8775; Csont, Tamás Bálint/0000-0001-5792-2768}
}