TY - JOUR AU - Kelemen-Valkony, Ildikó AU - Kiss, Márton AU - Csiha, Judit AU - Kiss, András Attila AU - Bircher, Urs AU - Szidonya, János AU - Maróy, Péter AU - Juhász, Gábor AU - Komonyi, Orban AU - Csiszar, Katalin AU - Mink, Mátyás TI - Drosophila basement membrane collagen col4a1 mutations cause severe myopathy JF - MATRIX BIOLOGY J2 - MATRIX BIOL VL - 31 PY - 2012 IS - 1 SP - 29 EP - 37 PG - 9 SN - 0945-053X DO - 10.1016/j.matbio.2011.09.004 UR - https://m2.mtmt.hu/api/publication/2104514 ID - 2104514 N1 - Department of Genetics, University of Szeged, Középfasor 52, H-6726 Szeged, Hungary John A. Burns School of Medicine, University of Hawaii, 1960 East West Road, Honolulu, HI 96822, United States Department of General Zoology, Eötvös Loránd University, Pázmány sétány 1/C, H-1117 Budapest, Hungary Cited By :21 Export Date: 2 September 2019 CODEN: MTBOE Correspondence Address: Mink, M.; Department of Genetics, University of Szeged, Középfasor 52, H-6726 Szeged, Hungary; email: mink@bio.u-szeged.hu Chemicals/CAS: Collagen Type IV; Mutant Proteins LA - English DB - MTMT ER - TY - JOUR AU - Ryder, E AU - Ashburner, M AU - Bautista, Llacer R AU - Drummond, J AU - Webster, J AU - Johnson, G AU - Morley, T AU - Chan, YS AU - Blows, F AU - Coulson, D AU - Reuter, G AU - Baisch, H AU - Apelt, C AU - Kauk, A AU - Rudolph, T AU - Kube, M AU - Klimm, KM AU - Nickel, C AU - Szidonya, János AU - Maróy, Péter AU - Pál, Margit AU - Rasmuson, Lestander A AU - Ekstrom, K AU - Stocker, H AU - Hugentobler, C AU - Hafen, E AU - Gubb, D AU - Pflugfelder, G AU - Dorner, C AU - Mechler, B AU - Schenkel, H AU - Marhold, J AU - Serras, F AU - Corominas, M AU - Punset, A AU - Roote, J AU - Russell, S TI - The Drosdel Deletion Collection: A Drosophila Genomewide Chromosomal Deficiency Resource JF - GENETICS J2 - GENETICS VL - 177 PY - 2007 IS - 1 SP - 615 EP - 629 PG - 15 SN - 0016-6731 DO - 10.1534/genetics.107.076216 UR - https://m2.mtmt.hu/api/publication/1915229 ID - 1915229 N1 - Megjegyzés-22232557 Z9: 53 DI: 10.1534/genetics.107.076216 AB - We describe a second-gene ration deficiency kit for Drosophila melanogaster composed of molecularly mapped deletions on an isogenic background, covering similar to 77% of the Release 5.1 genome. Using a previously reported collection of FRT-bearing P-element insertions, we have generated 655 new deletions and verified a set of 209 deletion-bearing fly stocks. In addition to deletions, we demonstrate how the P elements may also be used to generate a set of custom inversions and duplications, particularly useful for balancing difficult regions of the genome carrying haplo-insufficient loci. We describe a simple computational resource that facilitates selection of appropriate elements for generating custom deletions. Finally, we provide a computational resource that facilitates selection of other mapped FRT-bearing elements that, when combined with the DrosDel collection, can theoretically generate over half a million precisely mapped deletions. LA - English DB - MTMT ER - TY - JOUR AU - Ryder, E AU - Blows, F AU - Ashburner, M AU - Bautista-Llacer, R AU - Coulson, D AU - Drummond, J AU - Webster, J AU - Gubb, D AU - Gunton, N AU - Johnson, G AU - O, Kane CJ AU - Huen, D AU - Sharma, P AU - Asztalos, Zoltán Imre AU - Baisch, H AU - Schulze, J AU - Kube, M AU - Kittlaus, K AU - Reuter, G AU - Maróy, Péter AU - Szidonya, János AU - Rasmuson-Lestander, A AU - Ekstrom, K AU - Dickson, B AU - Hugentobler, C AU - Stocker, H AU - Hafen, E AU - Lepesant, JA AU - Pflugfelder, G AU - Heisenberg, M AU - Mechler, B AU - Serras, F AU - Corominas, M AU - Schneuwly, S AU - Preat, T AU - Roote, J AU - Russell, S TI - The DrosDel collection: A set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster JF - GENETICS J2 - GENETICS VL - 167 PY - 2004 IS - 2 SP - 797 EP - 813 PG - 17 SN - 0016-6731 DO - 10.1534/genetics.104.026658 UR - https://m2.mtmt.hu/api/publication/1921708 ID - 1921708 AB - We describe a collection of P-element insertions that have considerable utility for generating custom chromosomal aberrations in Drosophila melanogaster. We have mobilized a pair of engineered P elements, p{RS3} and p{RS5}, to collect 3243 lines unambiguously mapped to the Drosophila genome sequence. The collection contains, on average, an element every 35 kb. We demonstrate the utility of the collection for generating custom chromosomal deletions that have their end points mapped, with base-pair resolution, to the genome sequence. The collection was generated in an isogenic strain, thus affording a uniform background for screens where sensitivity to genetic background is high. The entire collection, along with a computational and genetic toolbox for designing and generating custom deletions, is publicly available. Using the collection it is theoretically possible to generate >12,000 deletions between 1 bp and 1 Mb in size by simple eye color selection. In addition, a further 37,000 deletions, selectable by molecular screening, may be generated. We are now rising the collection to generate a second-generation deficiency kit that is precisely mapped to the genome sequence. LA - English DB - MTMT ER - TY - JOUR AU - Deák, Péter AU - Omar, MM AU - Saunders, RDC AU - Pál, Margit AU - Komonyi, O AU - Szidonya, János AU - Maróy, Péter AU - Zhang, Y AU - Ashburner, M AU - more, null TI - P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: Correlation of physical and cytogenetic maps in chromosomal region 86E-87F JF - GENETICS J2 - GENETICS VL - 147 PY - 1997 SP - 1697 EP - 1722 PG - 26 SN - 0016-6731 UR - https://m2.mtmt.hu/api/publication/1912173 ID - 1912173 LA - English DB - MTMT ER - TY - JOUR AU - DORN, R AU - Szidonya, János AU - KORGE, G AU - SEHNERT, M AU - TAUBERT, H AU - ARCHOUKIEH, E AU - TSCHIERSCH, B AU - MORAWIETZ, H AU - WUSTMANN, G AU - Hoffmann, Gyula AU - REUTER, G TI - P-TRANSPOSON-INDUCED DOMINANT ENHANCER MUTATIONS OF POSITION-EFFECT VARIEGATION IN DROSOPHILA-MELANOGASTER JF - GENETICS J2 - GENETICS VL - 133 PY - 1993 IS - 2 SP - 279 EP - 290 PG - 12 SN - 0016-6731 DO - 10.1093/genetics/133.2.279 UR - https://m2.mtmt.hu/api/publication/1722630 ID - 1722630 N1 - : FN Thomson Reuters Web of Knowledge Z9: 44 WC: Genetics & Heredity AB - P transposon induced modifier mutations of position-effect variegation (PEV) were isolated with the help of hybrid dysgenic crosses (pi2 strain) and after transposition of the mutator elements pUChsneory+ and P[lArB]. Enhancer mutations were found with a ten times higher frequency than suppressors. The 19 pUChsneory+- and 15 P[lArB]-induced enhancer mutations can be used for cloning of genomic sequences at the insertion sites of the mutator elements via plasmid rescue. Together with a large sample of X-ray-induced (48) and spontaneous (93) enhancer mutations a basic genetic analysis of this group of modifier genes was performed. On the basis of complementation and mapping data we estimate the number of enhancer genes at about 30 in the third chromosome and between 50 and 60 for the whole autosome complement. Therefore, enhancer of PEV loci are found in the Drosophila genome as frequently as suppressor genes. Many of the enhancer mutations display paternal effects consistent with the hypothesis that some of these mutations can induce genomic imprinting. First studies on the developmentally regulated gene expression of PEV enhancer genes were performed by beta-galactosidase staining in P[lArB] induced mutations. LA - English DB - MTMT ER - TY - JOUR AU - Szidonya, János AU - Farkas, Tibor AU - Páli, Tibor TI - The fatty acid constitution and ordering state of membranes in dominant temperature sensitive letal mutation and wild type Drosophila melanogaster larvae. JF - BIOCHEMICAL GENETICS J2 - BIOCHEM GENET VL - 28 PY - 1990 SP - 233 EP - 246 PG - 14 SN - 0006-2928 DO - 10.1007/BF02401414 UR - https://m2.mtmt.hu/api/publication/1903889 ID - 1903889 LA - English DB - MTMT ER - TY - JOUR AU - WUSTMANN, G AU - Szidonya, János AU - REUTER, G TI - The genetics of position-effect variegation modifying loci in Drosophila melanogaster. JF - MOLECULAR & GENERAL GENETICS J2 - MOL GEN GENET VL - 217 PY - 1989 SP - 520 EP - 527 PG - 8 SN - 0026-8925 DO - 10.1007/BF02464926 UR - https://m2.mtmt.hu/api/publication/1903645 ID - 1903645 LA - English DB - MTMT ER - TY - JOUR AU - Szabad, János AU - Erdélyi, Miklós AU - Hoffmann, Gyula AU - Szidonya, János AU - WRIGHT, TRF TI - ISOLATION AND CHARACTERIZATION OF DOMINANT FEMALE STERILE MUTATIONS OF DROSOPHILA-MELANOGASTER .2. MUTATIONS ON THE 2ND CHROMOSOME JF - GENETICS J2 - GENETICS VL - 122 PY - 1989 IS - 4 SP - 823 EP - 835 PG - 13 SN - 0016-6731 DO - 10.1093/genetics/122.4.823 UR - https://m2.mtmt.hu/api/publication/1722696 ID - 1722696 LA - English DB - MTMT ER - TY - JOUR AU - Szabad, János AU - Erdélyi, Miklós AU - Szidonya, János TI - Characterization of FS(2)1, a germ-line dependent dominant female sterile mutation of Drosophila. JF - ACTA BIOLOGICA HUNGARICA (1983-2018) J2 - ACTA BIOL HUNG VL - 38 PY - 1987 IS - 2 SP - 257 EP - 266 PG - 10 SN - 0236-5383 UR - https://m2.mtmt.hu/api/publication/1903123 ID - 1903123 LA - English DB - MTMT ER - TY - JOUR AU - SEMESHIN, VF AU - Szidonya, János TI - EM mapping of rearrangement in the 24-25 section of Drosophila melanogaster 2L chromosomes. JF - DROSOPHILA INFORMATION SERVICE J2 - DROSOPHILA INFORMATION SERVICE VL - 61 PY - 1985 SP - 148 EP - 154 PG - 7 SN - 0070-7333 UR - https://m2.mtmt.hu/api/publication/1901987 ID - 1901987 LA - English DB - MTMT ER -