@article{MTMT:33721840,
	title = {A spinalis izomatrophia személyre szabott terápiás lehetőségei},
	url = {https://m2.mtmt.hu/api/publication/33721840},
	author = {Szabó-Taylor, Katalin and Molnár, Mária Judit},
	doi = {10.18071/isz.76.0077},
	journal-iso = {IDEGGYOGY SZEMLE},
	journal = {IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE},
	volume = {76},
	unique-id = {33721840},
	issn = {0019-1442},
	abstract = {Spinal muscular atrophy (SMA) is an autosomal recessive disease leading to progressive muscle weakness and atrophy, in severe cases also affecting the bulbar and respiratory muscles.The clinical spectrum of the disease is extremely variable, in the most severe cases resulting in perinatal death, while at the least severe end of the spectrum causing some motor deficits in old age without the loss of ambulation. Spinal muscular atrophy care has changed dramatically in recent years due to the availability of new therapeutic options. The FDA approved nusinersen in 2016, this was followed by the approval of onasemnogene abeparvovec in 2019 and risdiplam in 2020. The EMA approved all three therapies a year later. Two of the threapies work at the pre-mRNA level, one at the DNA level. The clinical studies leading to the approval of the three drugs included patients of different ages and clinical conditions, and utilised partly different motor and functional scales. Therefore, direct comparison of these clinical studies is not possible. However, an increasing amount of real-world data contribute to the better understanding of the efficacy of the different therapies for patients of different ages and clinical conditions, in a real-world setting. Thus, the question may arise “Which is the best SMA therapy?”. This is an impossible question to answer. Indeed the question “Which therapy is the most suitable for a certain patient at a certain time?” is much more realistic. Here, we provide a brief overview of the objectively measurable results of the three therapies to date and an outlook into future therapeutic avenues.},
	year = {2023},
	eissn = {2498-6208},
	pages = {77-94},
	orcid-numbers = {Szabó-Taylor, Katalin/0000-0002-4763-3521; Molnár, Mária Judit/0000-0001-9350-1864}
}

@article{MTMT:33334444,
	title = {Upregulation of exofacial peroxiredoxin-thioredoxin system of lymphocytes and monocytes in preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/33334444},
	author = {Alasztics, Bálint and Kovács, Árpád Ferenc and Pállinger, Éva and Szabó-Taylor, Katalin and Szabó, Gábor and Molvarec, Attila and Koller, Ákos and Rigó, János},
	doi = {10.1016/j.preghy.2022.12.002},
	journal-iso = {PREGNANCY HYPERTENS},
	journal = {PREGNANCY HYPERTENSION},
	volume = {31},
	unique-id = {33334444},
	issn = {2210-7789},
	year = {2023},
	eissn = {2210-7797},
	pages = {54-59},
	orcid-numbers = {Alasztics, Bálint/0000-0002-4011-8439; Kovács, Árpád Ferenc/0000-0002-7742-160X; Pállinger, Éva/0000-0002-5789-0951; Szabó-Taylor, Katalin/0000-0002-4763-3521; Szabó, Gábor/0000-0002-8573-8260; Molvarec, Attila/0000-0002-3229-3034; Koller, Ákos/0000-0003-3256-8701; Rigó, János/0000-0003-2762-6516}
}

@article{MTMT:32189675,
	title = {Formation of a protein corona on the surface of extracellular vesicles in blood plasma},
	url = {https://m2.mtmt.hu/api/publication/32189675},
	author = {Tóth, Eszter Ágnes and Turiák, Lilla and Visnovitz, Tamás and Cserép, Csaba and Türk-Mázló, Anett and Sódar, Barbara and Försönits, András and Petővári, Gábor and Sebestyén, Anna and Komlósi, Zsolt and Drahos, László and Kittel, Ágnes and Nagy, György and Bácsi, Attila and Dénes, Ádám and Song Gho, Yong and Szabó-Taylor, Katalin and Buzás, Edit Irén},
	doi = {10.1002/jev2.12140},
	journal-iso = {J EXTRACELLULAR VESICL},
	journal = {JOURNAL OF EXTRACELLULAR VESICLES},
	volume = {10},
	unique-id = {32189675},
	year = {2021},
	eissn = {2001-3078},
	orcid-numbers = {Visnovitz, Tamás/0000-0002-7962-5083; Cserép, Csaba/0000-0001-5513-2471; Sódar, Barbara/0000-0002-8803-7304; Försönits, András/0000-0002-9298-8890; Petővári, Gábor/0000-0002-1957-2864; Sebestyén, Anna/0000-0001-8814-4794; Komlósi, Zsolt/0000-0002-4149-1497; Drahos, László/0000-0001-9589-6652; Nagy, György/0000-0003-1198-3228; Szabó-Taylor, Katalin/0000-0002-4763-3521; Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:30604411,
	title = {Surface protein cargo of extracellular vesicles in blood plasma; the effect of an inflammatory disease on the vesicle surface protein interactome},
	url = {https://m2.mtmt.hu/api/publication/30604411},
	author = {Tóth, Eszter Ágnes and Szabó-Taylor, Katalin and Visnovitz, Tamás and Nagy, György and Buzás, Edit Irén},
	journal-iso = {J EXTRACELLULAR VESICL},
	journal = {JOURNAL OF EXTRACELLULAR VESICLES},
	volume = {8},
	unique-id = {30604411},
	year = {2019},
	eissn = {2001-3078},
	pages = {140-140},
	orcid-numbers = {Szabó-Taylor, Katalin/0000-0002-4763-3521; Visnovitz, Tamás/0000-0002-7962-5083; Nagy, György/0000-0003-1198-3228; Buzás, Edit Irén/0000-0002-3744-206X}
}

@inbook{MTMT:30391582,
	title = {Kakucs Archaeological Expedition},
	url = {https://m2.mtmt.hu/api/publication/30391582},
	author = {Jaeger, M. and Kirleis, W. and Kiss, Viktória and Kulcsár, Gabriella and Müller, J. and Staniuk, R. and Szabó-Taylor, Katalin},
	booktitle = {Kakucs-Turján a Middle Bronze Age multi-layered fortified settlement in Central Hungary},
	unique-id = {30391582},
	year = {2018},
	pages = {13-21},
	orcid-numbers = {Szabó-Taylor, Katalin/0000-0002-4763-3521}
}

@article{MTMT:3403202,
	title = {Molecular interactions at the surface of extracellular vesicles},
	url = {https://m2.mtmt.hu/api/publication/3403202},
	author = {Buzás, Edit Irén and Tóth, Eszter Ágnes and Sódar, Barbara and Szabó-Taylor, Katalin},
	doi = {10.1007/s00281-018-0682-0},
	journal-iso = {SEMIN IMMUNOPATHOL},
	journal = {SEMINARS IN IMMUNOPATHOLOGY},
	volume = {40},
	unique-id = {3403202},
	issn = {1863-2297},
	abstract = {Extracellular vesicles such as exosomes, microvesicles, apoptotic bodies, and large oncosomes have been shown to participate in a wide variety of biological processes and are currently under intense investigation in many different fields of biomedicine. One of the key features of extracellular vesicles is that they have relatively large surface compared to their volume. Some extracellular vesicle surface molecules are shared with those of the plasma membrane of the releasing cell, while other molecules are characteristic for extracellular vesicular surfaces. Besides proteins, lipids, glycans, and nucleic acids are also players of extracellular vesicle surface interactions. Being secreted and present in high number in biological samples, collectively extracellular vesicles represent a uniquely large interactive surface area which can establish contacts both with cells and with molecules in the extracellular microenvironment. Here, we provide a brief overview of known components of the extracellular vesicle surface interactome and highlight some already established roles of the extracellular vesicle surface interactions in different biological processes in health and disease.},
	year = {2018},
	eissn = {1863-2300},
	pages = {453-464},
	orcid-numbers = {Buzás, Edit Irén/0000-0002-3744-206X; Sódar, Barbara/0000-0002-8803-7304; Szabó-Taylor, Katalin/0000-0002-4763-3521}
}

@article{MTMT:3353499,
	title = {Detection and proteomic characterization of extracellular vesicles in human pancreatic juice},
	url = {https://m2.mtmt.hu/api/publication/3353499},
	author = {Osteikoetxea, Xabier and Benke, Márton and Rodriguez, M and Pálóczi, Krisztina and Sódar, Barbara and Szvicsek, Zsuzsanna and Szabó-Taylor, Katalin and Visnovitzné Dr Vukman, Krisztina and Kittel, Ágnes and Wiener, Zoltán and Vékey, Károly and Harsányi, László and Szűcs, Ákos and Turiák, Lilla and Buzás, Edit Irén},
	doi = {10.1016/j.bbrc.2018.03.107},
	journal-iso = {BIOCHEM BIOPH RES CO},
	journal = {BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS},
	volume = {499},
	unique-id = {3353499},
	issn = {0006-291X},
	abstract = {AIMS: The prognosis of patients with pancreatic cancer has remained virtually unchanged with a high mortality rate compared to other types of cancers. An earlier detection would provide a time window of opportunity for treatment and prevention of deaths. In the present study we investigated extracellular vesicle (EV)-associated potential biomarkers for pancreatic cancer by directly assessing EV size-based subpopulations in pancreatic juice samples of patients with chronic pancreatitis or pancreatic cancer. In addition, we also studied blood plasma and pancreatic cancer cell line-derived EVs. METHODS: Comparative proteomic analysis was performed of 102EV preparations from human pancreatic juices, blood, and pancreatic cancer cell lines Capan-1 and MIA PaCa-2. EV preparations were also characterized by electron microscopy, tunable resistive pulse sensing, and flow cytometry. RESULTS: Here we describe the presence of EVs in human pancreatic juice samples. Pancreatic juice EV-associated proteins that we identified as possible candidate markers for pancreatic cancer included mucins, such as MUC1, MUC4, MUC5AC, MUC6 and MUC16, CFTR, and MDR1 proteins. These candidate biomarkers could also be detected by flow cytometry in EVs found in pancreatic juice and those secreted by pancreatic cancer cell lines. CONCLUSIONS: Together our data show that detection and characterization of EVs directly in pancreatic juice is feasible and may prove to be a valuable source of potential biomarkers of pancreatic cancer.},
	year = {2018},
	eissn = {1090-2104},
	pages = {37-43},
	orcid-numbers = {Osteikoetxea, Xabier/0000-0003-3628-0174; Benke, Márton/0000-0002-8438-7438; Pálóczi, Krisztina/0000-0001-7065-3582; Sódar, Barbara/0000-0002-8803-7304; Szabó-Taylor, Katalin/0000-0002-4763-3521; Wiener, Zoltán/0000-0001-7056-4926; Harsányi, László/0000-0003-2657-0039; Buzás, Edit Irén/0000-0002-3744-206X}
}

@CONFERENCE{MTMT:30391726,
	title = {Technológiák Kakucson – csonteszközök használata egy középső bronzkori településen (KEX BONE)},
	url = {https://m2.mtmt.hu/api/publication/30391726},
	author = {Kulcsár, Gabriella and Gál, Erika and Szabó-Taylor, Katalin and Jaeger, M},
	booktitle = {Momos X. Őskori technikák, őskori technológiák},
	unique-id = {30391726},
	year = {2017},
	pages = {28},
	orcid-numbers = {Gál, Erika/0000-0002-4226-3218; Szabó-Taylor, Katalin/0000-0002-4763-3521}
}

@article{MTMT:3254659,
	title = {Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA},
	url = {https://m2.mtmt.hu/api/publication/3254659},
	author = {Németh, Andrea and Orgován, Norbert and Sódar, Barbara and Osteikoetxea, Xabier and Pálóczi, Krisztina and Szabó-Taylor, Katalin and Visnovitzné Dr Vukman, Krisztina and Kittel, Ágnes and Turiák, Lilla and Wiener, Zoltán and Tóth, Sára and Drahos, László and Vékey, Károly and Horváth, Róbert and Buzás, Edit Irén},
	doi = {10.1038/s41598-017-08392-1},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {7},
	unique-id = {3254659},
	issn = {2045-2322},
	year = {2017},
	eissn = {2045-2322},
	orcid-numbers = {Németh, Andrea/0000-0002-0015-8436; Sódar, Barbara/0000-0002-8803-7304; Osteikoetxea, Xabier/0000-0003-3628-0174; Pálóczi, Krisztina/0000-0001-7065-3582; Szabó-Taylor, Katalin/0000-0002-4763-3521; Wiener, Zoltán/0000-0001-7056-4926; Tóth, Sára/0000-0001-9852-0458; Drahos, László/0000-0001-9589-6652; Horváth, Róbert/0000-0001-8617-2302; Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:3214054,
	title = {Monocyte activation drives preservation of membrane thiols by promoting release of oxidised membrane moieties via extracellular vesicles},
	url = {https://m2.mtmt.hu/api/publication/3214054},
	author = {Szabó-Taylor, Katalin and Tóth, Eszter Ágnes and Balogh, AM and Sódar, Barbara and Kadar, L and Pálóczi, Krisztina and Fekete, Nóra and Németh, Andrea and Osteikoetxea, Xabier and Visnovitzné Dr Vukman, Krisztina and Holub Marianna, Csilla and Pállinger, Éva and Nagy, György and Winyard, PG and Buzás, Edit Irén},
	doi = {10.1016/j.freeradbiomed.2017.03.016},
	journal-iso = {FREE RADICAL BIO MED},
	journal = {FREE RADICAL BIOLOGY AND MEDICINE},
	volume = {108},
	unique-id = {3214054},
	issn = {0891-5849},
	abstract = {The redox state of cellular exofacial molecules is reflected by the amount of available thiols. Furthermore, surface thiols can be considered as indicators of immune cell activation. One group of thiol containing proteins, peroxiredoxins, in particular, have been associated with inflammation. In this study, we assessed surface thiols of the U937 and Thp1 monocyte cell lines and primary monocytes in vitro upon inflammatory stimulation by irreversibly labelling the cells with a fluorescent derivative of maleimide. We also investigated exofacial thiols on circulating blood mononuclear cells in patients with rheumatoid arthritis and healthy controls. When analysing extracellular vesicles, we combined thiol labelling with the use of antibodies to specific CD markers to exclude extracellular vesicle mimicking signals from thiol containing protein aggregates. Furthermore, differential detergent lysis was applied to confirm the vesicular nature of the detected extracellular events in blood plasma. We found an increase in exofacial thiols on monocytes upon in vitro stimulation by LPS or TNF, both in primary monocytes and monocytic cell lines (p<0.0005). At the same time, newly released extracellular vesicles showed a decrease in their exofacial thiols compared with those from unstimulated cells (p<0.05). We also found a significant elevation of surface thiols on circulating monocytes in rheumatoid arthritis patients (p<0.05) and newly released extracellular vesicles of isolated CD14+ cells from rheumatoid arthritis patients had decreased thiol levels compared with healthy subjects (p<0.01). Exofacial peroxiredoxin 1 was demonstrated on the surface of primary and cultured monocytes, and the number of peroxiredoxin 1 positive extracellular vesicles was increased in rheumatoid arthritis blood plasma (p<0.05). Furthermore, an overoxidised form of peroxiredoxin was detected in extracellular vesicle-enriched preparations from blood plasma. Our data show that cell surface thiols play a protective role and reflect oxidative stress resistance state in activated immune cells. Furthermore, they support a role of extracellular vesicles in the redox regulation of human monocytes, possibly representing an antioxidant mechanism.},
	year = {2017},
	eissn = {1873-4596},
	pages = {56-65},
	orcid-numbers = {Szabó-Taylor, Katalin/0000-0002-4763-3521; Sódar, Barbara/0000-0002-8803-7304; Pálóczi, Krisztina/0000-0001-7065-3582; Németh, Andrea/0000-0002-0015-8436; Osteikoetxea, Xabier/0000-0003-3628-0174; Holub Marianna, Csilla/0000-0002-5772-665X; Pállinger, Éva/0000-0002-5789-0951; Nagy, György/0000-0003-1198-3228; Buzás, Edit Irén/0000-0002-3744-206X}
}