TY - JOUR AU - Gera, Tamás Bence AU - Kondász, Bence AU - Smausz Kolumbán, Tamás AU - Heszlerné Kopniczky, Judit AU - Hodovány, Szabolcs AU - Ajtai, Tibor AU - Szabó-Révész, Piroska AU - Ambrus, Rita AU - Csóka, Ildikó AU - Hopp, Béla TI - Pulsed laser ablation of polymer-based magnetic nanocomposites for oil spill remediation JF - CLEANER MATERIALS J2 - CLEANER MATERIALS VL - 11 PY - 2024 SN - 2772-3976 DO - 10.1016/j.clema.2024.100235 UR - https://m2.mtmt.hu/api/publication/34723729 ID - 34723729 LA - English DB - MTMT ER - TY - JOUR AU - Smausz Kolumbán, Tamás AU - Kondász, Bence TI - Multiexposure laser speckle contrast analysis system calibration limited by perfusion-dependent scattering on the skin JF - JOURNAL OF BIOMEDICAL OPTICS J2 - J BIOMED OPT VL - 28 PY - 2023 IS - 9 PG - 10 SN - 1083-3668 DO - 10.1117/1.JBO.28.9.096006 UR - https://m2.mtmt.hu/api/publication/34144534 ID - 34144534 LA - English DB - MTMT ER - TY - JOUR AU - Nagy, Eszter AU - Heszlerné Kopniczky, Judit AU - Smausz Kolumbán, Tamás AU - Náfrádi, Máté AU - Alapi, Tünde AU - Bohus, János AU - Pajer, Viktor AU - Révész, Piroska AU - Ambrus, Rita AU - Hopp, Béla TI - A comparative study of femtosecond pulsed laser ablation of meloxicam in distilled water and in air JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 13 PY - 2023 IS - 1 PG - 12 SN - 2045-2322 DO - 10.1038/s41598-023-36922-7 UR - https://m2.mtmt.hu/api/publication/34034385 ID - 34034385 N1 - Department of Optics and Quantum Electronics, University of Szeged, Dóm tér 9, Szeged, 6720, Hungary Department of Inorganic and Analytical Chemistry, University of Szeged, Dóm tér 7, Szeged, 6720, Hungary ELI ALPS, ELI-HU Non-Profit Ltd., Wolfgang Sandner utca 3, Szeged, 6728, Hungary Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Eötvös utca 6, Szeged, 6720, Hungary Export Date: 21 September 2023 Correspondence Address: Hopp, B.; Department of Optics and Quantum Electronics, Dóm tér 9, Hungary; email: bhopp@physx.u-szeged.hu AB - The increasing prevalence of water insoluble or poorly soluble drugs calls for the development of new formulation methods. Common approaches include the reduction of particle size and degree of crystallinity. Pulsed laser ablation is a clean technique for producing sub-micrometre sized drug particles and has the potential to induce amorphization. We studied the effect of femtosecond pulsed laser ablation (ELI ALPS THz pump laser system: λ c = 781 nm, τ = 135 fs) on meloxicam in distilled water and in air. The ablated particles were characterized chemically, morphologically and in terms of crystallinity. We demonstrated that femtosecond laser ablation can induce partial amorphization of the particles in addition to a reduction in particle size. In the case of femtosecond pulsed laser ablation in air, the formation of pure meloxicam spheres showed that this technique can produce amorphous meloxicam without the use of excipients, which is a unique result. We also aimed to describe the ablation processes in both investigated media. LA - English DB - MTMT ER - TY - CONF AU - Ludasi, Krisztina AU - Sovány, Tamás AU - Jójártné Laczkovich, Orsolya AU - Hopp, Béla AU - Smausz Kolumbán, Tamás AU - Regdon, Géza (ifj.) TI - Lézerrel a gyógyszerhamisítás ellen T2 - Gyógyszertechnológiai és Ipari Gyógyszerészeti Konferencia 2022: A Magyar Gyógyszerésztudományi Társaság Gyógyszeripari Szervezetének és Gyógyszertechnológiai Szakosztályának Konferenciája PY - 2022 SP - 30 EP - 30 PG - 1 UR - https://m2.mtmt.hu/api/publication/33569293 ID - 33569293 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Homik, Zsolt AU - Heszlerné Kopniczky, Judit AU - Smausz Kolumbán, Tamás AU - Berkesi, Dániel Simon AU - Hopp, Béla TI - Formation of gold/silver composite nanoparticles by pulsed laser ablation of gold–silver layered films in liquid JF - APPLIED PHYSICS A - MATERIALS SCIENCE AND PROCESSING J2 - APPL PHYS A-MATER VL - 128 PY - 2022 IS - 9 PG - 13 SN - 0947-8396 DO - 10.1007/s00339-022-05938-7 UR - https://m2.mtmt.hu/api/publication/33134651 ID - 33134651 AB - Nanoparticles of high purity can be produced from a variety of materials by pulsed laser ablation of solids in liquid. Composite nanoparticles are of great importance in various applications such as catalysis or biomedicine and the process of their formation is still a subject of intense research. In this work, gold/silver composite nanoparticles were synthesized in aqueous media by ns pulsed laser ablation of gold–silver multilayer targets with different absolute layer thicknesses and layer thickness ratios. The generated nanoparticles showed a log-normal distribution of sizes, with average diameter in the 20–40 nm range and standard deviation of 9–30 nm. By comparing the UV–VIS absorbance spectra of the nanoparticle colloids with two theoretical calculations (based on the Mie and the BEM model), it was found that there is a direct correlation between the average Au and Ag content of the nanoparticles and the composition of the films on the substrate. Assuming thermal ablation, our model calculations showed that there is a maximum thickness of the top layer up to which both layers can be ablated simultaneously and alloy nanoparticles can be produced. LA - English DB - MTMT ER - TY - JOUR AU - Nagy, Eszter AU - Homik, Zsolt AU - Smausz Kolumbán, Tamás AU - Heszlerné Kopniczky, Judit AU - Náfrádi, Máté AU - Alapi, Tünde AU - Kókai, Dávid AU - Burián, Katalin AU - Révész, Piroska AU - Ambrus, Rita AU - Hopp, Béla TI - A comprehensive analysis of meloxicam particles produced by nanosecond laser ablation as a wet milling technique JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 12 PY - 2022 IS - 1 PG - 13 SN - 2045-2322 DO - 10.1038/s41598-022-16728-9 UR - https://m2.mtmt.hu/api/publication/33029379 ID - 33029379 N1 - Department of Optics and Quantum Electronics, University of Szeged, Dóm tér 9, Szeged, 6720, Hungary Department of Inorganic and Analytical Chemistry, University of Szeged, Dóm tér 7, Szeged, 6720, Hungary Department of Medical Microbiology, Albert Szent-Györgyi Medical School, University of Szeged, Dóm tér 10, Szeged, 6720, Hungary Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Eötvös utca 6, Szeged, LA - English DB - MTMT ER - TY - JOUR AU - Kondász, Bence AU - Hopp, Béla AU - Smausz Kolumbán, Tamás TI - Mixed scattering as a problem in laser speckle contrast analysis JF - APPLIED OPTICS J2 - APPL OPTICS VL - 60 PY - 2021 IS - 22 SP - 6593 EP - 6599 PG - 7 SN - 1559-128X DO - 10.1364/AO.428785 UR - https://m2.mtmt.hu/api/publication/32337027 ID - 32337027 AB - Static scattering is detrimental to the accuracy of laser speckle contrast analysis (LASCA) measurements on skin when, instead of percentile change monitoring, absolute perfusion values are needed, e.g., for tissue injury examination. Perfusion values were calculated using two evaluation models, while changing the dynamic/static scattering ratio of monitored skin and tissue phantoms. Results were strongly affected by the significant increase of static contribution. Measurements on a modified tissue phantom showed that the changes in the measured perfusion values were mostly caused by the mixed scattering, which was omitted by the tested models. Dynamic ratio values obtained by multi-exposure LASCA could be used for perfusion data correction. (C) 2021 Optical Society of America LA - English DB - MTMT ER - TY - JOUR AU - Gera, Tamás Bence AU - Smausz Kolumbán, Tamás AU - Ajtai, Tibor AU - Kurilla, Boldizsár AU - Homik, Zsolt AU - Heszlerné Kopniczky, Judit AU - Bozóki, Zoltán AU - Révész, Piroska AU - Ambrus, Rita AU - Hopp, Béla TI - Production of ibuprofen-magnetite nanocomposites by pulsed laser ablation JF - JOURNAL OF PHYSICS D-APPLIED PHYSICS J2 - J PHYS D APPL PHYS VL - 54 PY - 2021 IS - 39 PG - 11 SN - 0022-3727 DO - 10.1088/1361-6463/ac07df UR - https://m2.mtmt.hu/api/publication/32218309 ID - 32218309 LA - English DB - MTMT ER - TY - JOUR AU - Ludasi, Krisztina AU - Jójártné Laczkovich, Orsolya AU - Sovány, Tamás AU - Hopp, Béla AU - Smausz Kolumbán, Tamás AU - Andrásik, Attila AU - Gera, Tamás Bence AU - Kovács, Zsolt AU - Regdon, Géza (ifj.) TI - Anti-counterfeiting protection, personalized medicines - Development of 2D identification methods using laser technology JF - INTERNATIONAL JOURNAL OF PHARMACEUTICS J2 - INT J PHARM VL - 605 PY - 2021 PG - 12 SN - 0378-5173 DO - 10.1016/j.ijpharm.2021.120793 UR - https://m2.mtmt.hu/api/publication/32101093 ID - 32101093 N1 - Összes idézések száma a WoS-ban: 0 LA - English DB - MTMT ER - TY - JOUR AU - Nagy, Eszter AU - Andrásik, Attila AU - Smausz Kolumbán, Tamás AU - Ajtai, Tibor AU - Kun-Szabó, Fruzsina AU - Heszlerné Kopniczky, Judit AU - Bozóki, Zoltán AU - Révész, Piroska AU - Ambrus, Rita AU - Hopp, Béla TI - Fabrication of Submicrometer-Sized Meloxicam Particles Using Femtosecond Laser Ablation in Gas and Liquid Environments JF - NANOMATERIALS J2 - NANOMATERIALS-BASEL VL - 11 PY - 2021 IS - 4 PG - 12 SN - 2079-4991 DO - 10.3390/nano11040996 UR - https://m2.mtmt.hu/api/publication/31971131 ID - 31971131 N1 - Department of Optics and Quantum Electronics, University of Szeged, Dóm tér 9, Szeged, 6720, Hungary Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Eötvös utca 6, Szeged, 6720, Hungary Interdisciplinary Excellence Centre, Department of Materials Science, University of Szeged, Dugonics tér 13, Szeged, 6720, Hungary Export Date: 29 September 2021 Correspondence Address: Nagy, E.; Department of Optics and Quantum Electronics, Dóm tér 9, Hungary; email: nagyeszter.physx@gmail.com Funding details: TUDFO/47138-1/2019-ITM Funding details: Magyar Tudományos Akadémia, MTA Funding details: Ministry for Innovation and Technology, GINOP-2.3.2-15-2016-00036 Funding text 1: Acknowledgments: This work was supported by the ÚNKP-19-3-SZTE-208 New National Excellence Program of the Ministry for Innovation and Technology, the GINOP-2.3.2-15-2016-00036 grant (“Development and application of multimodal optical nanoscopy methods in life and materials sciences”) and the Ministry of Human Capacities, Hungary grant (TUDFO/47138-1/2019-ITM FIKP program). T. Ajtai is indebted for his János Bolyai Research Scholarship of the Hungarian Academy of Sciences. The authors wish to thank Bálint Nagyillés from the TeWaTi group of the University of Szeged for his essential contribution to the laser system operation. Funding text 2: This work was supported by the ?NKP-19-3-SZTE-208 New National Excellence Program of the Ministry for Innovation and Technology, the GINOP-2.3.2-15-2016-00036 grant (?Development and application of multimodal optical nanoscopy methods in life and materials sciences?) and the Ministry of Human Capacities, Hungary grant (TUDFO/47138-1/2019-ITM FIKP program). T. Ajtai is indebted for his J?nos Bolyai Research Scholarship of the Hungarian Academy of Sciences. The authors wish to thank B?lint Nagyill?s from the TeWaTi group of the University of Szeged for his essential contribution to the laser system operation. LA - English DB - MTMT ER -