@article{MTMT:34335469,
	title = {Efficacy of high dose systemic versus combined (systemic and intratympanic) corticosteroid therapy in idiopathic sudden sensorineural hearing loss : A prospective randomized trial and risk factor analysis},
	url = {https://m2.mtmt.hu/api/publication/34335469},
	author = {Kovács, Márton and Uzsaly, János Gáspár and Bodzai, G and Pap, István and Lippai, Bálint and Dergez, Tímea and Németh, Adrienn and Gerlinger, Imre and Szanyi, István and Bakó, Péter},
	doi = {10.1016/j.amjoto.2023.104099},
	journal-iso = {AM J OTOLARYNG},
	journal = {AMERICAN JOURNAL OF OTOLARYNGOLOGY},
	volume = {45},
	unique-id = {34335469},
	issn = {0196-0709},
	abstract = {The pathophysiology and the proper treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) are an ongoing subject of debate. Locally or systemic administered corticosteroids are the most accepted drugs of treatment in reference to ISSNHL (idiopathic sudden sensorineural hearing loss), however, no strong evidence nor guidelines regarding their effectiveness yet exists. In our prospective, randomized, controlled trial 78 participants were enrolled. Patients were randomly assigned based on the day of admission to two groups according to treatment: group SS (n = 43) received intravenous systemic methylprednisolone alone, and group CT (n = 35) received intratympanic dexamethasone + systemic methylprednisolone. The primary outcome was to compare the hearing outcomes between the treatment groups based on different, widely accepted categories (Siegel, Kanzaki, modified Siegel and PTA4 gain). In consideration of the secondary outcome, we examined the effect of the various risk factors on the hearing improvement. No differences were detected regarding hearing improvement between the two groups, based on any criteria [Siegel's criteria (p = 0.604); Kanzaki's criteria (p = 0.720); modified Siegel's criteria (p = 0.524) and PTA 4 gain (p = 0.569)]. However, several clinical factors such as vertigo (p = 0.039), or cardiovascular comorbidity (p = 0.02) and the severity of initial hearing loss (p = 0.033) were found to bear a significant impact upon the hearing outcome. To the best of our knowledge, this is the first randomized controlled trial comparing high dose systemic and combination corticosteroid therapy in ISSNHL patients. Our findings suggest coexisting cardiovascular comorbidity, vertigo and severity of the initial hearing loss may bear a significantly higher impact upon hearing improvement, than the additional intratympanic steroid administration. The presented trial was registered in the European Union Drug Regulating Authorities Clinical Trials Database (name: Combinated systemic and intratympanic steroid therapy in idiopathic sudden sensorineural hearing loss, No.: 2017-000658-20) and with the ethical approval of The National Institute of Pharmacy and Nutrition (OGYÉI) (protocol No.: 7621, on 2017.02.16.).},
	keywords = {risk factor; steroid; Sudden hearing loss; Intratympanic injection},
	year = {2024},
	eissn = {1532-818X},
	orcid-numbers = {Lippai, Bálint/0009-0004-9117-1063}
}

@article{MTMT:33806009,
	title = {Matching the pitch perception of the cochlear implanted ear with the contralateral ear in patients with single-sided deafness: a novel approach},
	url = {https://m2.mtmt.hu/api/publication/33806009},
	author = {Tóth, Tamás Ferenc and Németh, Adrienn and Bakó, Péter and Révész, Péter and Gerlinger, Imre and Szanyi, István},
	doi = {10.1007/s00405-023-08002-z},
	journal-iso = {EUR ARCH OTO-RHINO-L},
	journal = {EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY},
	volume = {280},
	unique-id = {33806009},
	issn = {0937-4477},
	year = {2023},
	eissn = {1434-4726},
	pages = {4851-4859}
}

@article{MTMT:33764466,
	title = {Genetic Etiology of Nonsyndromic Hearing Loss in Hungarian Patients},
	url = {https://m2.mtmt.hu/api/publication/33764466},
	author = {Pál, Margit and Nagy, Dóra and Neller, Alexandra and Farkas, Katalin and Török, Dóra and Nagy, Nikoletta and Füstös, Dalma and Nagy, Roland and Németh, Adrienn and Szilvássy, Judit and Rovó, László and Kiss, József Géza and Széll, Márta},
	doi = {10.3390/ijms24087401},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {24},
	unique-id = {33764466},
	issn = {1661-6596},
	abstract = {Hearing loss is the most prevalent sensory disorder worldwide. The majority of congenital nonsyndromic hearing loss (NSHL) cases are caused by hereditary factors. Previously, the majority of NSHL studies focused on the GJB2 gene; however, with the availability of next-generation sequencing (NGS) methods, the number of novel variants associated with NSHL has increased. The purpose of this study was to design effective genetic screening for a Hungarian population based on a pilot study with 139 NSHL patients. A stepwise, comprehensive genetic approach was developed, including bidirectional capillary sequencing, multiplex ligation-dependent probe amplification (MLPA), and an NGS panel of 108 hearing loss genes. With our results, a genetic diagnosis was possible for 92 patients. Sanger sequencing and MLPA identified the genetic background of 50% of these diagnosed cases, and the NGS panel identified another 16%. The vast majority (92%) of the diagnosed cases showed autosomal recessive inheritance and 76% were attributed to GJB2. The implementation of this stepwise analysis markedly increased our diagnostic yield and proved to be cost-effective as well.},
	year = {2023},
	eissn = {1422-0067},
	orcid-numbers = {Pál, Margit/0000-0003-3662-0837; Nagy, Dóra/0000-0002-6224-1972; Nagy, Nikoletta/0000-0001-8576-7953; Németh, Adrienn/0000-0001-9965-0609; Rovó, László/0000-0003-1782-1756; Széll, Márta/0000-0002-0730-714X}
}

@article{MTMT:33255083,
	title = {Tág aquaeductus vestibuli okozta harmadikablak-szindróma komplex sebészeti ellátása},
	url = {https://m2.mtmt.hu/api/publication/33255083},
	author = {Szabó, Éva and Molnár, Krisztián and Kovács, Márton and Németh, Adrienn and Beke, Zsolt and Gerlinger, Imre and Szanyi, István and Bakó, Péter},
	journal-iso = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	journal = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	volume = {68},
	unique-id = {33255083},
	issn = {0016-237X},
	year = {2022},
	pages = {153-155}
}

@article{MTMT:33255050,
	title = {III. típusú inkomplett partíció - a cochlea ritka fejlődési rendellenessége, amely komoly kihívás a cochlearis implantációt végzőknek},
	url = {https://m2.mtmt.hu/api/publication/33255050},
	author = {Gerlinger, Imre and Bakó, Péter and Németh, Adrienn and Szanyi, István and Perényi, Ádám and Horváth, Bence and Rovó, László},
	journal-iso = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	journal = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	volume = {68},
	unique-id = {33255050},
	issn = {0016-237X},
	year = {2022},
	pages = {147-152}
}

@article{MTMT:33202705,
	title = {Subtotal Petrosectomy and Cochlear Implantation in Children With Chronic Suppurative Otitis Media: A Single Institutional Experience},
	url = {https://m2.mtmt.hu/api/publication/33202705},
	author = {Bakó, Péter and Kovács, Márton and Uzsaly, János Gáspár and Burián, András and Bodzai, Greta and Németh, Adrienn and Tóth, Arnold and Szanyi, István and Gerlinger, Imre},
	doi = {10.7874/jao.2022.00220},
	journal-iso = {Journal of Audiology and Otology},
	journal = {Journal of Audiology and Otology},
	volume = {26},
	unique-id = {33202705},
	issn = {2384-1621},
	abstract = {Chronic suppurative otitis media (CSOM) with or without cholesteatoma is a frequent chronic inflammatory condition in children, which may lead to severe hearing loss that affects speech development. Treatment of recurrent CSOM associated with unserviceable hearing requires a specialized approach with regard to disease eradication and hearing rehabilitation. In this study, we investigated the advantages of subtotal petrosectomy (SP) combined with cochlear implantation (CI) in children with CSOM associated with unserviceable hearing and describe our experience with regard to the efficacy of this method, together with a literature review.SP with sequential or simultaneous CI was performed in three children (four ears), and postoperative audiometric data were recorded.The study included two male and one female patient. Mean age at the time of SP was 10.75 years (7-13 years). Sequential implantation was performed in three ears. Facial nerve palsy occurred after SP in one patient. The latest word recognition scores of Cases 1, 2, and 3 were 80% (at 60 dB), 75% (at 60 dB), and 70% (at 50 dB) and 90% (at 50 dB), respectively.SP with CI may be safe and reliable in children with CSOM associated with unserviceable hearing.},
	keywords = {Otologic Surgical Procedures; cochlear implantation; otitis media; Correction of hearing impairment; Suppurative},
	year = {2022},
	pages = {214-222}
}

@article{MTMT:32711829,
	title = {TUBB4B gene mutation in Leber phenotype of congenital amaurosis syndrome associated with early-onset deafness},
	url = {https://m2.mtmt.hu/api/publication/32711829},
	author = {Maász, Anita and Hadzsiev, Kinga and Ripszám, Réka and Zsigmond, Anna and Maka, Erika and Knézy, Krisztina and Lesch, Balázs and Németh, Adrienn and Bene, Judit and Gálik, Bence and Gyenesei, Attila and Melegh, Béla},
	doi = {10.1016/j.ejmg.2022.104471},
	journal-iso = {EUR J MED GENET},
	journal = {EUROPEAN JOURNAL OF MEDICAL GENETICS},
	volume = {65},
	unique-id = {32711829},
	issn = {1769-7212},
	year = {2022},
	eissn = {1878-0849},
	orcid-numbers = {Maka, Erika/0000-0002-3631-3506; Lesch, Balázs/0000-0002-6289-4797}
}

@article{MTMT:32508864,
	title = {Az endoszkópos I-es típusú tympanoplastica ugyanolyan hatékony, mint a mikroszkópos I-es típusú tympanoplastica, de kevésbé invazív - Metaanalízis},
	url = {https://m2.mtmt.hu/api/publication/32508864},
	author = {Pap, István and Tóth, István and Szakács, Zsolt and Gede, Noémi and Koukkoullis, Alexandros and Révész, Péter and Harmat, Kinga and Németh, Adrienn and Lujber, László and Bocskai, Tímea and Hegyi, Péter and Varga, Gábor and Gerlinger, Imre and Szanyi, István},
	journal-iso = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	journal = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	volume = {67},
	unique-id = {32508864},
	issn = {0016-237X},
	keywords = {[Meta-analysis]},
	year = {2021},
	pages = {139-146},
	orcid-numbers = {Szakács, Zsolt/0000-0002-7035-941X; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:32298322,
	title = {A Vibrant Soundbridge aktív középfül-implantátum történeti áttekintése és sebészi alkalmazásának lehetőségei = Historical overview and surgical applications of the Vibrant Soundbridge active middle ear implant},
	url = {https://m2.mtmt.hu/api/publication/32298322},
	author = {Tóth, Tamás Ferenc and Gerlinger, Imre and Bölcsföldi T., Barbara and Kellényi, György and Németh, Adrienn and Papp, István and Szanyi, István},
	doi = {10.1556/650.2021.32216},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {162},
	unique-id = {32298322},
	issn = {0030-6002},
	abstract = {Összefoglaló. A Vibrant Soundbridge aktív középfül-implantátum vezetéses, sensorineuralis és kevert típusú halláscsökkenés esetén is megoldást jelenthet a beteg hallásrehabilitációja során. Sensorineuralis halláscsökkenés esetén akkor indikálható, ha a légvezetéses hallásküszöb nem haladja meg a 80-85 dBHL-t a 3-4 kHz frekvenciákon, vezetéses, illetve kevert típusú halláscsökkenés esetén pedig akkor, ha a csontvezetéses hallásküszöb nem haladja meg a 45-65 dBHL-t a 0,5-4 kHz közti frekvenciatartományban. Az implantátum beültetését eleinte tisztán sensorineuralis halláscsökkenés esetén végezték, és csupán egyféleképpen történhetett: a rezgéskeltő rendszer oldalán lévő rögzítőcsipeszt rá kellett applikálni az incus hosszú nyújtványára. Azokra az esetekre, amikor a rezgéskeltő rögzítése nem kivitelezhető, különböző rögzítőelemeket (coupler) fejlesztettek ki. Az incusra való rögzítés hosszúnyújtvány-couplerrel, illetve rövidnyújtvány-couplerrel lehetséges. Vezetéses és kevert típusú halláscsökkenés esetén a kerek ablak membránjához is illeszthető a rendszer, előrehaladott otosclerosis esetén pedig a Soundbridge-implantáció stapedotomiával kiegészített változata ("power stapes") hozhat kielégítő halláseredményt. Ezek a technikák meglehetősen megnövelték a sebész szabadságát, így széles körben alkalmazott, megbízható megoldássá váltak. A Pécsi Tudományegyetem Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinikáján az elmúlt évtizedben számos incusvibroplastica történt, de kerekablak-vibroplasticára is több alkalommal sor került. A jelen összefoglaló tanulmányban a Vibrant Soundbridge implantátum technikai fejlődésének történeti áttekintésén felül az alkalmazható műtéti megoldásokat mutatjuk be. Orv Hetil. 2021; 162(40): 1619-1626. Summary. The Vibrant Soundbridge active middle ear implant can provide a reliable solution for hearing rehabilitation of patients with conductive, sensorineural or mixed hearing loss. For sensorineural hearing loss, the air conduction threshold of the patient should not be more increased than 80-85 dBHL at the range of 3-4 kHz, and for conductive and mixed hearing loss, the bone conduction threshold should not be more increased than 45-65 dBHL between 0.5 and 4 kHz. The standard surgical procedure was originally designed for purely sensorineural hearing loss, and the fixation clip of the vibrating transducer needed to be crimped onto the long process of the incus. In many cases, it is impossible to crimp the vibrator onto the incus. In order to solve such circumstances, fixation clips (couplers) have been developed. There are two options to crimp the device on the incus: applying a long process coupler or a short process coupler. For conductive or mixed hearing loss, a round window soft coupler has been introduced. In advanced otosclerotic cases, a special combined technique of Soundbridge implantation with simultaneous stapedotomy can result in sufficient hearing rehabilitation. These techniques significantly broadened the scale of possibilities for the implantation, therefore, it became a widely utilized, reliable procedure. At the Department of Otorhino-laryngology, Clinical Center, University of Pécs, in addition to a noteworthy amount of incus vibroplasty, several cases of round window vibroplasty have also been performed. The aim of the present study is to summarize the history of development of the Vibrant Soundbridge and to present an overview of the applicable surgical techniques. Orv Hetil. 2021; 162(40): 1619-1626.},
	keywords = {surgical technique; Middle ear implant; középfül-implantátum; Vibrant Soundbridge; coupler; műtéti technika},
	year = {2021},
	eissn = {1788-6120},
	pages = {1619-1626}
}

@{MTMT:31638611,
	title = {The efficacy of chlorine dioxide containing mouthwashes in the oral hygiene – a meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/31638611},
	author = {Kerémi, Beáta and Márta, Katalin and Borbásné Farkas, Kornélia and Czumbel, László Márk and Tóth, Barbara and Szakács, Zsolt and Csupor, Dezső and Czimmer, J and Rumbus, Zoltán and Révész, Péter and Németh, Adrienn and Gerber, Gábor and Hegyi, Péter and Varga, Gábor},
	booktitle = {Proceedings of the EFOP-3.6.2-16-2017-00006 (LIVE LONGER) project},
	unique-id = {31638611},
	year = {2020},
	pages = {35-35},
	orcid-numbers = {Kerémi, Beáta/0000-0003-4000-9440; Márta, Katalin/0000-0002-2213-4865; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Czumbel, László Márk/0000-0002-5915-0383; Tóth, Barbara/0000-0002-6086-8819; Szakács, Zsolt/0000-0002-7035-941X; Csupor, Dezső/0000-0002-4088-3333; Gerber, Gábor/0000-0003-0256-2608; Hegyi, Péter/0000-0003-0399-7259; Varga, Gábor/0000-0002-5506-8198}
}