@article{MTMT:34558800,
	title = {The oral microbiome of a family including Papillon-Lefèvre-syndrome patients and clinically healthy members},
	url = {https://m2.mtmt.hu/api/publication/34558800},
	author = {Vályi, Péter and Wirth, Roland and Minárovits, János and Strang, Orsolya and Maróti, Gergely and Kovács, Kornél Lajos},
	doi = {10.1186/s12903-024-03856-z},
	journal-iso = {BMC ORAL HEALTH},
	journal = {BMC ORAL HEALTH},
	volume = {24},
	unique-id = {34558800},
	issn = {1472-6831},
	abstract = {The oral microbiota composition of patients diagnosed with Papillon-Lefèvre-syndrome and treated for several years were compared to those existing in the oral cavity of the clinically healthy family members and a cohort of patients having various stages of chronic periodontitis.},
	year = {2024},
	eissn = {1472-6831},
	orcid-numbers = {Vályi, Péter/0000-0002-9594-2038; Wirth, Roland/0000-0002-2383-2323; Strang, Orsolya/0000-0002-0259-9091; Maróti, Gergely/0000-0002-3705-0461; Kovács, Kornél Lajos/0000-0002-3926-0497}
}

@article{MTMT:34127552,
	title = {Interaction of biomolecules with anatase, rutile and amorphous TiO2 surfaces: A molecular dynamics study},
	url = {https://m2.mtmt.hu/api/publication/34127552},
	author = {Tarjányi, Tamás and Bogár, Ferenc and Minárovits, János and Gajdács, Márió and Tóth, Zsolt},
	doi = {10.1371/journal.pone.0289467},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {18},
	unique-id = {34127552},
	issn = {1932-6203},
	abstract = {The adhesion of biomolecules to dental and orthopedic implants is a fundamental step in the process of osseointegration. Short peptide motifs, such as RGD or KRSR, carried by extracellular matrix proteins or coated onto implant surfaces, accelerate cell adhesion and tissue formation. For this reason, understanding the binding mechanisms of adhesive peptides to oxidized surfaces of titanium implants is of paramount importance. We performed molecular dynamics simulations to compare the adhesion properties of 6 peptides, including the tripeptide RGD, its variants KGD and LGD, as well as the tetrapeptide KRSR, its variant LRSR and its truncated version RSR, on anatase, rutile, and amorphous titanium dioxide (TiO 2 ) surfaces. The migration of these molecules from the water phase to the surface was simulated in an aqueous environment. Based on these simulations, we calculated the residence time of each peptide bound to the three different TiO 2 structures. It was found that the presence of an N-terminal lysine or arginine amino acid residue resulted in more efficient surface binding. A pulling simulation was performed to detach the adhered molecules. The maximum pulling force and the binding energy were determined from the results of these simulations. The tri- and tetrapeptides had slightly greater adhesion affinity to the amorphous and anatase structure than to rutile in general, however specific surface and peptide binding characters could be detected. The binding energies obtained from our simulations allowed us to rank the adhesion strengths of the studied peptides.},
	year = {2023},
	eissn = {1932-6203},
	orcid-numbers = {Tarjányi, Tamás/0000-0002-9481-5977; Bogár, Ferenc/0000-0002-0611-1452; Gajdács, Márió/0000-0003-1270-0365}
}

@{MTMT:33562016,
	title = {Daganatvírusok},
	url = {https://m2.mtmt.hu/api/publication/33562016},
	author = {Minárovits, János},
	booktitle = {Orvosi virológia},
	unique-id = {33562016},
	year = {2022},
	pages = {502-506}
}

@CONFERENCE{MTMT:33162598,
	title = {Átvitt HIV gyógyszer-rezisztencia jelentősége a klinikai gyakorlatban},
	url = {https://m2.mtmt.hu/api/publication/33162598},
	author = {Áy, Éva and Adravecz, Lilla and Pocskay, Ágnes and Müller, Viktor and Lakatos, Botond and Szlávik, János and Pék, Tamás and Marschalkó, Márta and Tóth, Béla and Kárpáti, Sarolta and Mezei, Mária and Minárovits, János},
	booktitle = {Magyar Infektológiai és Klinikai Mikrobiológiai Társaság 49. Kongresszusa},
	unique-id = {33162598},
	year = {2022},
	pages = {62-62},
	orcid-numbers = {Pék, Tamás/0000-0001-5189-8656; Kárpáti, Sarolta/0000-0002-8472-0712}
}

@CONFERENCE{MTMT:33118459,
	title = {Osszeointegráció molekuláris megközelítésben: kristályos és amorf titán-oxid felületekkel kölcsönható biomolekulák},
	url = {https://m2.mtmt.hu/api/publication/33118459},
	author = {Tarjányi, Tamás and Bogár, Ferenc and Gajdács, Márió and Minárovits, János and Tóth, Zsolt},
	booktitle = {Szegedi Fogorvosnapok 2022. Szegedi Fogorvos Találkozó és Tudományos Konferencia, Magyar Gyermekfogászati és Fogszabályozási Társaság IX. Tóth Pál Vándorgyűlés},
	unique-id = {33118459},
	year = {2022},
	pages = {25-25},
	orcid-numbers = {Tarjányi, Tamás/0000-0002-9481-5977; Bogár, Ferenc/0000-0002-0611-1452; Gajdács, Márió/0000-0003-1270-0365}
}

@{MTMT:33094830,
	title = {Coronaviridae},
	url = {https://m2.mtmt.hu/api/publication/33094830},
	author = {Takács, Mária and Minárovits, János},
	booktitle = {Orvosi virológia},
	unique-id = {33094830},
	year = {2022},
	pages = {154-162}
}

@article{MTMT:32788115,
	title = {Megemlékezés Földes István mikrobiológus, az orvostudomány doktora születésének centenáriumán = A Tribute to István Földes, DSc, Microbiologist on the Centenary of his Birth},
	url = {https://m2.mtmt.hu/api/publication/32788115},
	author = {Minárovits, János},
	doi = {10.1556/2065.183.2022.2.12},
	journal-iso = {MAGYAR TUDOMÁNY},
	journal = {MAGYAR TUDOMÁNY},
	volume = {183},
	unique-id = {32788115},
	issn = {0025-0325},
	year = {2022},
	eissn = {1588-1245},
	pages = {247-249}
}

@article{MTMT:32581214,
	title = {Integrative profiling of Epstein–Barr virus transcriptome using a multiplatform approach},
	url = {https://m2.mtmt.hu/api/publication/32581214},
	author = {Fülöp, Ádám and Torma, Gábor and Moldován, Norbert and Szenthe, Kálmán and Bánáti, Ferenc and Almsarrhad, Islam and Csabai, Zsolt and Tombácz, Dóra and Minárovits, János and Boldogkői, Zsolt},
	doi = {10.1186/s12985-021-01734-6},
	journal-iso = {VIROL J},
	journal = {VIROLOGY JOURNAL},
	volume = {19},
	unique-id = {32581214},
	issn = {1743-422X},
	abstract = {Background Epstein-Barr virus (EBV) is an important human pathogenic gammaherpesvirus with carcinogenic potential. The EBV transcriptome has previously been analyzed using both Illumina-based short read-sequencing and Pacific Biosciences RS II-based long-read sequencing technologies. Since the various sequencing methods have distinct strengths and limitations, the use of multiplatform approaches have proven to be valuable. The aim of this study is to provide a more complete picture on the transcriptomic architecture of EBV. Methods In this work, we apply the Oxford Nanopore Technologies MinION (long-read sequencing) platform for the generation of novel transcriptomic data, and integrate these with other's data generated by another LRS approach, Pacific BioSciences RSII sequencing and Illumina CAGE-Seq and Poly(A)-Seq approaches. Both amplified and non-amplified cDNA sequencings were applied for the generation of sequencing reads, including both oligo-d(T) and random oligonucleotide-primed reverse transcription. EBV transcripts are identified and annotated using the LoRTIA software suite developed in our laboratory. Results This study detected novel genes embedded into longer host genes containing 5 '-truncated in-frame open reading frames, which potentially encode N-terminally truncated proteins. We also detected a number of novel non-coding RNAs and transcript length isoforms encoded by the same genes but differing in their start and/or end sites. This study also reports the discovery of novel splice isoforms, many of which may represent altered coding potential, and of novel replication-origin-associated transcripts. Additionally, novel mono- and multigenic transcripts were identified. An intricate meshwork of transcriptional overlaps was revealed. Conclusions An integrative approach applying multi-technique sequencing technologies is suitable for reliable identification of complex transcriptomes because each techniques has different advantages and limitations, and the they can be used for the validation of the results obtained by a particular approach.},
	keywords = {EPSTEIN-BARR VIRUS; Transcriptome; SPLICE VARIANT; Herpesvirus; transcription start site; Long-read sequencing; nanopore sequencing; PacBio sequencing; transcript isoform; Transcription end site},
	year = {2022},
	eissn = {1743-422X},
	orcid-numbers = {Torma, Gábor/0000-0003-3241-0955; Moldován, Norbert/0000-0003-4138-586X; Bánáti, Ferenc/0000-0002-8999-523X; Csabai, Zsolt/0000-0003-0031-0116; Tombácz, Dóra/0000-0001-5520-2978; Boldogkői, Zsolt/0000-0003-1184-7293}
}

@article{MTMT:32020395,
	title = {Microbiomes in supragingival biofilms and saliva of adolescents with gingivitis and gingival health},
	url = {https://m2.mtmt.hu/api/publication/32020395},
	author = {Wirth, Roland and Maróti, Gergely and Lipták, Lídia and Mester, Mónika Klára and Al Ayoubi, Alaa and Pap, Bernadett and Madléna, Melinda and Minárovits, János and Kovács, Kornél Lajos},
	doi = {10.1111/odi.13883},
	journal-iso = {ORAL DIS},
	journal = {ORAL DISEASES},
	volume = {28},
	unique-id = {32020395},
	issn = {1354-523X},
	abstract = {Background Important alterations exist in the microbiomes of supragingival biofilm and saliva samples from adolescent patients developing induced or spontaneous gingivitis relative to healthy controls. These and the relationships to dental health are not fully understood yet. Subjects and Methods Supragingival biofilm samples (n = 36) were collected from the teeth of 9 adolescents with gingivitis induced by orthodontic appliances, as well as dental plaques (n = 40) from 10 adolescents with spontaneous gingivitis, in addition to similar samples (n = 36) from 9 healthy controls. The bacterial metagenomes were analyzed by 16S rRNA gene amplicon sequencing. Salivary microbiomes of the same persons were characterized by shotgun metagenome sequencing. The data sets were examined using advanced bioinformatics workflows and two reference databases. Results The composition and diversity of bacterial communities did not differ extensively among the three study groups. Nevertheless, the relative abundances of the genera Fusobacterium, Akkermansia, Treponema, and Campylobacter were prominently higher in gingivitis patients versus controls. In contrast, the genera Lautropia, Kingella, Neisseria, Actinomyces, and Rothia were significantly more abundant in controls than in either of the two gingivitis groups. Conclusions The abundance pattern of certain taxa rather than individual strains shows characteristic features of potential diagnostic value. Stringent bioinformatics treatment of the sequencing data is mandatory to avoid unintentional misinterpretations.},
	year = {2022},
	eissn = {1601-0825},
	pages = {2000-2014},
	orcid-numbers = {Wirth, Roland/0000-0002-2383-2323; Maróti, Gergely/0000-0002-3705-0461; Madléna, Melinda/0000-0002-2154-3069; Kovács, Kornél Lajos/0000-0002-3926-0497}
}

@{MTMT:32776471,
	title = {Virus latency: Heterogeneity of host-virus interaction in shaping the virosphere},
	url = {https://m2.mtmt.hu/api/publication/32776471},
	author = {Chofong, G.N. and Minárovits, János and Richert-Pöggeler, K.R.},
	booktitle = {Plant Virus-Host Interaction},
	doi = {10.1016/B978-0-12-821629-3.00016-6},
	unique-id = {32776471},
	abstract = {Viruses and viroids that are not causing symptoms on their initial host plant are described by the terms “latent”, “cryptic” or “symptomless” and represent 6% and 2% of the classified plant viruses and viroids, respectively. Additionally, endogenous plant pararetroviruses that reside in their host genome are often dormant and therefore asymptomatic. Improved sequencing and diagnostic technology demonstrated that viral sequences are ubiquitously present in the biosphere even if the signs or symptoms of infection are not obvious. Accordingly, the number of latent plant viruses listed today does not reflect the true amount of latent viruses existing in plants. Biodiversity within the virosphere comprises virus-host, virus-vector, virus-virus and virus-viroid interactions. Invasion of new host plants, climatic changes and changes in plant production and distribution can have a major impact on symptomatic outbreaks of otherwise latent viruses which seem incapacitated but remain potentially undefeated. Here we describe for selected ornamentals how these changes can induce latent viruses and report on possible underlying biochemical mechanisms. Comparison of virus latency in plant and animal hosts indicates that epigenetic modifications are an important factor for regulation in both systems. © 2021 Elsevier Inc. All rights reserved.},
	keywords = {Retrovirus; Herpesvirus; Epigenetic regulation; Ornamental plant viruses; Latent viruses; Endogenous pararetrovirus},
	year = {2021},
	pages = {111-137}
}