@article{MTMT:30482041, title = {Reduction of gastrointestinal nitrosative stress by exogenous methane: neuroprotection through xanthine oxidoreductase inhibition}, url = {https://m2.mtmt.hu/api/publication/30482041}, author = {Poles, Marietta Zita and Bódi, Nikolett and Bagyánszki, Mária and Fekete, Éva and Tamás Mészáros, András and Varga, Gabriella and Szűcs, Szilárd and Nászai, Anna and Kiss, Liliána and Kozlov, Andrey and Boros, Mihály and Kaszaki, József}, journal-iso = {EUR SURG RES}, journal = {EUROPEAN SURGICAL RESEARCH}, volume = {59}, unique-id = {30482041}, issn = {0014-312X}, year = {2018}, eissn = {1421-9921}, pages = {36-36}, orcid-numbers = {Poles, Marietta Zita/0000-0003-4368-1275; Bódi, Nikolett/0000-0002-9774-1387; Bagyánszki, Mária/0000-0003-3533-9461; Varga, Gabriella/0000-0003-1888-8629; Boros, Mihály/0000-0003-1410-1999; Kaszaki, József/0000-0002-0750-7731} } @article{MTMT:3351594, title = {Reduction of nitrosative stress by methane: Neuroprotection through xanthine oxidoreductase inhibition in a rat model of mesenteric ischemia-reperfusion}, url = {https://m2.mtmt.hu/api/publication/3351594}, author = {Poles, Marietta Zita and Bódi, Nikolett and Bagyánszki, Mária and Fekete, Éva and Mészáros, András and Varga, Gabriella and Szűcs, Szilárd and Nászai, Anna and Kiss, Liliána and Kozlov, Andrey V and Boros, Mihály and Kaszaki, József}, doi = {10.1016/j.freeradbiomed.2018.03.024}, journal-iso = {FREE RADICAL BIO MED}, journal = {FREE RADICAL BIOLOGY AND MEDICINE}, volume = {120}, unique-id = {3351594}, issn = {0891-5849}, keywords = {NITROTYROSINE; MICROCIRCULATION; nitric oxide; ischemia-reperfusion; nitrogen biology; segment-specificity; nitrergic myenteric neurons, hypoxia}, year = {2018}, eissn = {1873-4596}, pages = {160-169}, orcid-numbers = {Poles, Marietta Zita/0000-0003-4368-1275; Bódi, Nikolett/0000-0002-9774-1387; Bagyánszki, Mária/0000-0003-3533-9461; Varga, Gabriella/0000-0003-1888-8629; Boros, Mihály/0000-0003-1410-1999; Kaszaki, József/0000-0002-0750-7731} } @article{MTMT:3314865, title = {A metáninhaláció elősegíti a myentericus nitrerg neuronok régióspecifikus adaptivitását patkány ischemia/reperfúzió modellen}, url = {https://m2.mtmt.hu/api/publication/3314865}, author = {Poles, Marietta Zita and Bódi, Nikolett and Bagyánszki, Mária and Fekete, Éva and Mészáros, András and Andrey, Kozlov and Boros, Mihály and Kaszaki, József}, journal-iso = {MAGYAR SEBÉSZET}, journal = {MAGYAR SEBÉSZET}, volume = {70}, unique-id = {3314865}, issn = {0025-0295}, year = {2017}, eissn = {1789-4301}, pages = {268-268}, orcid-numbers = {Poles, Marietta Zita/0000-0003-4368-1275; Bódi, Nikolett/0000-0002-9774-1387; Bagyánszki, Mária/0000-0003-3533-9461; Boros, Mihály/0000-0003-1410-1999; Kaszaki, József/0000-0002-0750-7731} } @misc{MTMT:3233709, title = {Methane Inhalation Enhances Adaptive Responses Of Nitrergic Neurons To Intestinal Ischemia-Reperfusion In A Region-Dependent Way In Rats}, url = {https://m2.mtmt.hu/api/publication/3233709}, author = {Poles, Marietta Zita and Bódi, Nikolett and Bagyánszki, Mária and Fekete, Éva and Mészáros, András and Kozlov, A and Boros, Mihály and Kaszaki, József}, editor = {Boros, Mihály and Vladimir, Jakovljevic and Dragan, M Djuric}, unique-id = {3233709}, year = {2017}, pages = {7-7}, orcid-numbers = {Poles, Marietta Zita/0000-0003-4368-1275; Bódi, Nikolett/0000-0002-9774-1387; Bagyánszki, Mária/0000-0003-3533-9461; Boros, Mihály/0000-0003-1410-1999; Kaszaki, József/0000-0002-0750-7731; Boros, Mihály/0000-0003-1410-1999} } @inproceedings{MTMT:3084698, title = {Exogén metán hatása a myentericus nitrerg neuronok kvantitatív sajátságaira és a bélcsatorna motilitására mesenterális ischaemia-reperfúzió alatt kísérletes patkánymodellen}, url = {https://m2.mtmt.hu/api/publication/3084698}, author = {Poles, Marietta Zita and Bódi, Nikolett and Talapka, Petra and Varga, Gabriella and Pál, Alexandra and Bagyánszki, Mária and Kaszaki, József and Fekete, Éva and Boros, Mihály}, booktitle = {Tavaszi Szél 2014 Konferencia = Spring Wind 2014: Konferenciakötet V.}, unique-id = {3084698}, year = {2014}, pages = {518-528}, orcid-numbers = {Poles, Marietta Zita/0000-0003-4368-1275; Bódi, Nikolett/0000-0002-9774-1387; Varga, Gabriella/0000-0003-1888-8629; Bagyánszki, Mária/0000-0003-3533-9461; Kaszaki, József/0000-0002-0750-7731; Boros, Mihály/0000-0003-1410-1999} } @article{MTMT:2870340, title = {Gut region-specific alterations in the composition of the intestinal microbiota in streptozotocin-induced diabetic rats}, url = {https://m2.mtmt.hu/api/publication/2870340}, author = {Bódi, Nikolett and Wirth, Roland and G, Maróti and Talapka, Petra and Fekete, Éva and K L, Kovács}, journal-iso = {UEG JOURNAL}, journal = {UNITED EUROPEAN GASTROENTEROLOGY JOURNAL}, volume = {2}, unique-id = {2870340}, issn = {2050-6406}, year = {2014}, eissn = {2050-6414}, orcid-numbers = {Bódi, Nikolett/0000-0002-9774-1387; Wirth, Roland/0000-0002-2383-2323} } @article{MTMT:2796003, title = {Alleviated mucosal and neuronal damage in a rat model of Crohn's disease}, url = {https://m2.mtmt.hu/api/publication/2796003}, author = {Talapka, Petra and Nagy, Lajos István and Pál, Alexandra and Poles, Marietta Zita and Magyariné, Berkó Anikó and Bagyánszki, Mária and Puskás, László and Fekete, Éva and Bódi, Nikolett}, doi = {10.3748/wjg.v20.i44.16690}, journal-iso = {WORLD J LGASTROENTEROL}, journal = {WORLD JOURNAL OF GASTROENTEROLOGY}, volume = {20}, unique-id = {2796003}, issn = {1007-9327}, abstract = {AIM: To establish a rat model suitable to investigate the repetitive relapsing inflammations (RRI) characteristic to Crohn's disease. METHODS: Colitis was induced by 2,4,6-trinitrobenzenesulfonic acid (TNBS). RRI were mimicked by repeating administrations of TNBS. Tissue samples were taken from control, once, twice and three times treated rats from the inflamed and adjacent non-inflamed colonic segments at different timepoints during the acute intestinal inflammation. The means of the ulcerated area were measured to evaluate the macroscopic mu-cosal damage. The density of myenteric neurons was determined on whole mounts by HuC/HuD immunohistochemistry. Heme oxygenase-1 (HO-1) expression was evaluated by molecular biological techniques. RESULTS: TNBS-treated rats displayed severe colitis, but the mortality was negligible, and an increase of body weight was characteristic throughout the experimental period. The widespread loss of myenteric neurons, and marked but transient HO-1 up-regulation were demonstrated after the first TNBS administration. After repeated doses the length of the recovery time and extent of the ulcerous colonic segments were markedly decreased, and the neuronal loss was on a smaller scale and was limited to the inflamed area. HO-1 mRNA level was notably greater than after a single dose and overexpression was sustained throughout the timepoints examined. Nevertheless, the HO-1 protein up-regulation after the second TNBS treatment proved to be transient. Following the third treatment HO-1 protein expression could not be detected. CONCLUSION: Experimentally provoked RRI may exert a protective preconditioning effect against the mucosal and neuronal damage. The persistent up-regulation of HO-1 mRNA expression may correlate with this. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.}, year = {2014}, eissn = {2219-2840}, pages = {16690-16697}, orcid-numbers = {Poles, Marietta Zita/0000-0003-4368-1275; Magyariné, Berkó Anikó/0000-0002-1237-5745; Bagyánszki, Mária/0000-0003-3533-9461; Bódi, Nikolett/0000-0002-9774-1387} } @article{MTMT:2789092, title = {Regionally Distinct Alterations in the Composition of the Gut Microbiota in Rats with Streptozotocin-Induced Diabetes}, url = {https://m2.mtmt.hu/api/publication/2789092}, author = {Wirth, Roland and Bódi, Nikolett and Maróti, Gergely and Bagyánszki, Mária and Talapka, Petra and Fekete, Éva and Bagi, Zoltán and Kovács, Kornél Lajos}, doi = {10.1371/journal.pone.0110440}, journal-iso = {PLOS ONE}, journal = {PLOS ONE}, volume = {9}, unique-id = {2789092}, issn = {1932-6203}, abstract = {The aim of this study was to map the microbiota distribution along the gut and establish whether colon/faecal samples from diabetic rats adequately reflect the diabetic alterations in the microbiome. Streptozotocin-treated rats were used to model type 1 diabetes mellitus (T1D). Segments of the duodenum, ileum and colon were dissected, and the microbiome of the lumen material was analysed by using next-generation DNA sequencing, from phylum to genus level. The intestinal luminal contents were compared between diabetic, insulin-treated diabetic and healthy control rats. No significant differences in bacterial composition were found in the luminal contents from the duodenum of the experimental animal groups, whereas distinct patterns were seen in the ileum and colon, depending on the history of the luminal samples. Ileal samples from diabetic rats exhibited particularly striking alterations, while the richness and diversity obscured some of the modifications in the colon. Characteristic rearrangements in microbiome composition and diversity were detected after insulin treatment, though the normal gut flora was not restored. The Proteobacteria displayed more pronounced shifts than those of the predominant phyla (Firmicutes and Bacteroidetes) in the rat model of T1D. Diabetes and insulin replacement affect the composition of the gut microbiota in different, gut region-specific manners. The luminal samples from the ileum appear more suitable for diagnostic purposes than the colon/faeces. The Proteobacteria should be at the focus of diagnosis and potential therapy. Klebsiella are recommended as biomarkers of T1D.}, keywords = {Body Weight; Adult; Male; COLON; DUODENUM; ARTICLE; controlled study; INSULIN; GLUCOSE; Rattus; nonhuman; glucose blood level; animal tissue; animal model; animal experiment; insulin treatment; insulin dependent diabetes mellitus; ILEUM; MICROBIAL DIVERSITY; PROTEOBACTERIA; Species richness; Klebsiella; intestine flora; SPECIES COMPOSITION; Firmicutes; Bacteroidetes; streptozotocin-induced diabetes mellitus; rat}, year = {2014}, eissn = {1932-6203}, orcid-numbers = {Wirth, Roland/0000-0002-2383-2323; Bódi, Nikolett/0000-0002-9774-1387; Maróti, Gergely/0000-0002-3705-0461; Bagyánszki, Mária/0000-0003-3533-9461; Bagi, Zoltán/0000-0001-7795-2024; Kovács, Kornél Lajos/0000-0002-3926-0497} } @article{MTMT:2727086, title = {Effect of methane on gastrointestinal motility in ischemia-reperfusion}, url = {https://m2.mtmt.hu/api/publication/2727086}, author = {Poles, Marietta Zita and Mészáros, András and Bódi, Nikolett and Bagyánszki, Mária and Varga, Gabriella and Fekete, Éva and Kaszaki, József and Boros, Mihály}, journal-iso = {MAGYAR SEBÉSZET}, journal = {MAGYAR SEBÉSZET}, volume = {67}, unique-id = {2727086}, issn = {0025-0295}, year = {2014}, eissn = {1789-4301}, pages = {235-236}, orcid-numbers = {Poles, Marietta Zita/0000-0003-4368-1275; Bódi, Nikolett/0000-0002-9774-1387; Bagyánszki, Mária/0000-0003-3533-9461; Varga, Gabriella/0000-0003-1888-8629; Kaszaki, József/0000-0002-0750-7731; Boros, Mihály/0000-0003-1410-1999} } @article{MTMT:2726239, title = {Gut region-specific rearrangement of the cellular and subcellular compartments of nitric oxide synthase isoforms after chronic ethanol consumption in rats}, url = {https://m2.mtmt.hu/api/publication/2726239}, author = {Bódi, Nikolett and Jancsó, Zsanett and Talapka, Petra and Pál, Alexandra and Poles, Marietta Zita and Bagyánszki, Mária and Hermesz, Edit and Fekete, Éva}, journal-iso = {HISTOL HISTOPATHOL}, journal = {HISTOLOGY AND HISTOPATHOLOGY}, volume = {29}, unique-id = {2726239}, issn = {0213-3911}, year = {2014}, eissn = {1699-5848}, pages = {1547-1555}, orcid-numbers = {Bódi, Nikolett/0000-0002-9774-1387; Jancsó, Zsanett/0000-0002-0572-5452; Poles, Marietta Zita/0000-0003-4368-1275; Bagyánszki, Mária/0000-0003-3533-9461; Hermesz, Edit/0000-0002-0543-6693} }