TY - CONF AU - Nochta-Kazsoki, Adrienn Katalin AU - Abboud, Houssam AU - Niczinger, Noémi AU - Nándor, Nagy AU - Zelkó, Romána TI - Development and characterization of a Nanofibrous Ophthalmic Insert for the Treatment of Age-related Macular Degeneration T2 - PhD Scientific Days 2024 PY - 2024 UR - https://m2.mtmt.hu/api/publication/35314817 ID - 35314817 LA - English DB - MTMT ER - TY - CONF AU - Abboud, Houssam AU - Eszter, Farkas AU - Nándor, Nagy AU - Balázs, Pinke AU - Zelkó, Romána AU - Nochta-Kazsoki, Adrienn Katalin TI - Development of Levofloxacin-loaded Electrospun Nanofibrous Ocular Insert for the Treatment of Antibacterial Conjunctivitis T2 - PhD Scientific Days 2024 PY - 2024 UR - https://m2.mtmt.hu/api/publication/35314738 ID - 35314738 LA - English DB - MTMT ER - TY - CONF AU - Abboud, Houssam AU - Eszter, Farkas AU - Nándor, Nagy AU - Balázs, Pinke AU - Zelkó, Romána AU - Nochta-Kazsoki, Adrienn Katalin TI - Development Levofloxacin-Loaded Electrospun Nanofibrous Ocular Insert for the Treatment of Antibacterial Conjunctivitis T2 - Congressus Pharmaceuticus Hungaricus XVII. and EUFEPS Annual Meeting 2024 PB - Magyar Gyógyszerésztudományi Társaság (MGYT) C1 - Budapest PY - 2024 SP - 181 EP - 182 PG - 2 UR - https://m2.mtmt.hu/api/publication/35314606 ID - 35314606 N1 - Poster presentation LA - English DB - MTMT ER - TY - JOUR AU - Farkas, Eszter AU - Abboud, Houssam AU - Nagy, Nándor AU - Hofmeister, Bálint AU - Ostorházi, Eszter AU - Tóth, Bence AU - Pinke, Balázs AU - Mészáros, László AU - Zelkó, Romána AU - Nochta-Kazsoki, Adrienn Katalin TI - Formulation and Development of Nanofiber-Based Ophthalmic Insert for the Treatment of Bacterial Conjunctivitis JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 25 PY - 2024 IS - 17 PG - 22 SN - 1661-6596 DO - 10.3390/ijms25179228 UR - https://m2.mtmt.hu/api/publication/35181230 ID - 35181230 LA - English DB - MTMT ER - TY - JOUR AU - Safaa, Mohammed Omer AU - Nagy, Nándor AU - Pinke, B. AU - Mészáros, László AU - Nochta-Kazsoki, Adrienn Katalin AU - Zelkó, Romána TI - Development and Evaluation of Different Electrospun Cysteamine-Loaded Nanofibrous Webs: A Promising Option for Treating a Rare Lysosomal Storage Disorder JF - PHARMACEUTICS J2 - PHARMACEUTICS VL - 16 PY - 2024 IS - 8 PG - 22 SN - 1999-4923 DO - 10.3390/pharmaceutics16081052 UR - https://m2.mtmt.hu/api/publication/35164929 ID - 35164929 LA - English DB - MTMT ER - TY - JOUR AU - Kürtösi, Balázs AU - Nochta-Kazsoki, Adrienn Katalin AU - Zelkó, Romána TI - A Systematic Review on Plant-Derived Extracellular Vesicles as Drug Delivery Systems JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 25 PY - 2024 IS - 14 PG - 19 SN - 1661-6596 DO - 10.3390/ijms25147559 UR - https://m2.mtmt.hu/api/publication/35093226 ID - 35093226 LA - English DB - MTMT ER - TY - JOUR AU - Rosário, Alexandra AU - Hankó, Balázs AU - Zelkó, Romána TI - Managing Drug Shortages in Pediatric Care JF - FRONTIERS IN PHARMACOLOGY J2 - FRONT PHARMACOL VL - 15 PY - 2024 PG - 11 SN - 1663-9812 DO - 10.3389/fphar.2024.1416029 UR - https://m2.mtmt.hu/api/publication/35061841 ID - 35061841 LA - English DB - MTMT ER - TY - JOUR AU - Benkő, Beáta Mária AU - Tóth, Gergő AU - Moldvai, Dorottya AU - Kádár, Szabina AU - Szabó, Edina AU - Szabó, Zoltán-István AU - Mazákné Kraszni, Márta AU - Szente, Lajos AU - Fiser, Béla AU - Sebestyén, Anna AU - Zelkó, Romána AU - Sebe, István TI - Cyclodextrin encapsulation enabling the anticancer repositioning of disulfiram: Preparation, analytical and in vitro biological characterization of the inclusion complexes JF - INTERNATIONAL JOURNAL OF PHARMACEUTICS J2 - INT J PHARM VL - 657 PY - 2024 PG - 14 SN - 0378-5173 DO - 10.1016/j.ijpharm.2024.124187 UR - https://m2.mtmt.hu/api/publication/34830527 ID - 34830527 N1 - Funding Agency and Grant Number: Semmelweis Science and Innovation Fund; New National Excellence Program of the Ministry for Culture and Innovation from National Research, Development and Innovation Fund [UNKP-23-3-II-SE- 95, UNKP-23-3-II-BME-88]; National Research, Development and Innovation Office, Hungary [TKP2021- NVA-14, NKFIH FK 146930, NKFI-K-142799] Funding text: This research was funded by the Semmelweis Science and Innovation Fund [I.S.: STIA-KFI 2022], by the New National Excellence Program of the Ministry for Culture and Innovation from the Source of the National Research, Development and Innovation Fund [B.M.B.: UNKP-23-3-II-SE- 95 and Sz.K.: UNKP-23-3-II-BME-88] and supported by the National Research, Development and Innovation Office, Hungary [B.F.: TKP2021- NVA-14; G.T.: NKFIH FK 146930; A.S.: NKFI-K-142799]. LA - English DB - MTMT ER - TY - JOUR AU - Romeo, Alessia AU - Nochta-Kazsoki, Adrienn Katalin AU - Musumeci, Teresa AU - Zelkó, Romána TI - A Clinical, Pharmacological, and Formulation Evaluation of Melatonin in the Treatment of Ocular Disorders—A Systematic Review JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 25 PY - 2024 IS - 7 PG - 21 SN - 1661-6596 DO - 10.3390/ijms25073999 UR - https://m2.mtmt.hu/api/publication/34768534 ID - 34768534 N1 - Submission received: 27 February 2024 / Revised: 25 March 2024 / Accepted: 1 April 2024 / Published: 3 April 2024 AB - Melatonin’s cytoprotective properties may have therapeutic implications in treating ocular diseases like glaucoma and age-related macular degeneration. Literature data suggest that melatonin could potentially protect ocular tissues by decreasing the production of free radicals and pro-inflammatory mediators. This study aims to summarize the screened articles on melatonin’s clinical, pharmacological, and formulation evaluation in treating ocular disorders. The identification of relevant studies on the topic in focus was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) guidelines. The studies were searched in the following databases and web search engines: Pubmed, Scopus, Science Direct, Web of Science, Reaxys, Google Scholar, Google Patents, Espacenet, and Patentscope. The search time interval was 2013–2023, with the following keywords: melatonin AND ocular OR ophthalmic AND formulation OR insert AND disease. Our key conclusion was that using melatonin-loaded nano-delivery systems enabled the improved permeation of the molecule into intraocular tissues and assured controlled release profiles. Although preclinical studies have demonstrated the efficacy of developed formulations, a considerable gap has been observed in the clinical translation of the results. To overcome this failure, revising the preclinical experimental phase might be useful by selecting endpoints close to clinical ones. LA - English DB - MTMT ER - TY - JOUR AU - Csorba, Anita AU - Katona, Gábor AU - Budai-Szűcs, Mária AU - Balogh Weiser, Diána AU - Molnár, P. AU - Maka, Erika AU - Nochta-Kazsoki, Adrienn Katalin AU - Vajna, Márton Antal AU - Zelkó, Romána AU - Nagy, Zoltán Zsolt AU - Balogh, György Tibor TI - A Comparative Pharmacokinetic Study for Cysteamine-Containing Eye Drops as an Orphan Topical Therapy in Cystinosis JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 25 PY - 2024 IS - 3 PG - 14 SN - 1661-6596 DO - 10.3390/ijms25031623 UR - https://m2.mtmt.hu/api/publication/34538437 ID - 34538437 N1 - Department of Ophthalmology, Semmelweis University, Mária Street 39, Budapest, H-1085, Hungary Institute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, Eötvös Street 6, Szeged, H-6720, Hungary Department of Physical Chemistry and Materials Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, H-1111, Hungary Molteam Llc., Mélyfúró Street 4, Budapest, H-1151, Hungary University Pharmacy Department of Pharmacy Administration, Semmelweis University, Hőgyes Endre Street 7-9, Budapest, H-1092, Hungary Department of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre Street 7-9, Budapest, H-1092, Hungary Export Date: 23 February 2024 Correspondence Address: Csorba, A.; Department of Ophthalmology, Mária Street 39, Hungary; email: csorba.anita@semmelweis-univ.hu Correspondence Address: Balogh, G.T.; Department of Pharmaceutical Chemistry, Hőgyes Endre Street 7-9, Hungary; email: balogh.gyorgy.tibor@semmelweis.hu LA - English DB - MTMT ER -