@article{MTMT:33648936,
	title = {Az aneuploidia eredete. A kevesebb és a több sem jó},
	url = {https://m2.mtmt.hu/api/publication/33648936},
	author = {Szabad, János and Zádori, János},
	journal-iso = {TERMÉSZET VILÁGA},
	journal = {TERMÉSZET VILÁGA},
	volume = {153},
	unique-id = {33648936},
	issn = {0040-3717},
	year = {2022},
	pages = {560-567}
}

@article{MTMT:33648918,
	title = {A kevesebb és a több sem jó. Az aneuploidia eredete és következményei},
	url = {https://m2.mtmt.hu/api/publication/33648918},
	author = {Zádori, János and Szabad, János},
	journal-iso = {TERMÉSZET VILÁGA},
	journal = {TERMÉSZET VILÁGA},
	volume = {153},
	unique-id = {33648918},
	issn = {0040-3717},
	year = {2022},
	pages = {512-517}
}

@book{MTMT:32661336,
	title = {Genetic Mosaicism},
	url = {https://m2.mtmt.hu/api/publication/32661336},
	isbn = {1527570584},
	author = {Szabad, János},
	publisher = {Cambridge Scholars Publishing},
	unique-id = {32661336},
	abstract = {The presence of green and yellow ornamental plants around us, dark spots on our skin, people with brown and blue mosaic irises, and white-spotted dogs and horses are all well-known phenomena of life, and are recognisable genetic mosaics. Although such genetics mosaics live with us (and, in fact, we are all a genetic mosaics), little is known about the genetic bases of their origin. This book provides a general overview of the mechanisms that lead to the formation of different types of mosaics, listing an ample collection of examples to illustrate the impact of the genetic mosaics on our life. The book will appeal to the reader interested in understanding the relationship between genetic events and mosaicism, especially undergraduate and graduate students and medical doctors, as well as experts engaged in horticulture and animal breeding.},
	keywords = {Mosaicism/*genetics},
	year = {2021}
}

@article{MTMT:31295471,
	title = {Control of Mating Plug Expelling and Sperm Storage in Drosophila: A Gynandromorph- and Mutation-Based Dissection},
	url = {https://m2.mtmt.hu/api/publication/31295471},
	author = {Szabad, János and Peng, Jing and Kubli, Eric},
	doi = {10.1556/019.70.2019.34},
	journal-iso = {BIOL FUTURA},
	journal = {BIOLOGIA FUTURA},
	volume = {70},
	unique-id = {31295471},
	issn = {2676-8615},
	abstract = {Introduction: In this study, we analyzed gynandromorphs with female terminalia, to dissect mating-related female behaviors in Drosophila. Materials and methods: We used gynandromorphs, experimentally modified wild-type (Oregon-R) females, and mutant females that lacked different components of the female reproductive apparatus. Results: Many of the gynandromorphs mated but did not expel the mating plug (MP). Some of these – with thousands of sperm in the uterus – failed to take up sperm into the storage organs. There were gynandromorphs that stored plenty of sperm but failed to release them to fertilize eggs. Expelling the MP, sperm uptake into the storage organs, and the release of stored sperm along egg production are separate steps occurring during Drosophila female fertility. Cuticle landmarks of the gynandromorphs revealed that while the nerve foci that control MP expelling and also those that control sperm uptake reside in the abdominal, the sperm release foci derive from the thoracic region of the blastoderm. Discussion and conclusion: The gynandromorph study is confirmed by analyses of (a) mutations that cause female sterility: Fs(3)Avar (preventing egg deposition), Tm2gs (removing germline cells), and iab-4DB (eliminating gonad formation) and (b) by experimentally manipulated wild-type
		females: decapitated or cut through ventral nerve cord.},
	year = {2019},
	eissn = {2676-8607},
	pages = {301-311}
}

@book{MTMT:31207173,
	title = {Genetikai mozaikok},
	url = {https://m2.mtmt.hu/api/publication/31207173},
	isbn = {9789633154076},
	author = {Szabad, János},
	publisher = {JATE Press Szegedi Egyetemi Kiadó},
	unique-id = {31207173},
	year = {2019}
}

@article{MTMT:3243692,
	title = {Mi van beleírva kromoszómáinkba?},
	url = {https://m2.mtmt.hu/api/publication/3243692},
	author = {Szabad, János},
	journal-iso = {TERMÉSZET VILÁGA},
	journal = {TERMÉSZET VILÁGA},
	volume = {148},
	unique-id = {3243692},
	issn = {0040-3717},
	year = {2017},
	pages = {242-246}
}

@article{MTMT:3006363,
	title = {Belső óra, napi ritmus},
	url = {https://m2.mtmt.hu/api/publication/3006363},
	author = {Szabad, János},
	journal-iso = {TERMÉSZET VILÁGA},
	journal = {TERMÉSZET VILÁGA},
	volume = {146},
	unique-id = {3006363},
	issn = {0040-3717},
	year = {2015},
	pages = {72-77}
}

@article{MTMT:2930170,
	title = {Élet a cserépodúban},
	url = {https://m2.mtmt.hu/api/publication/2930170},
	author = {Laukó, Zoltán and Szabad, János},
	journal-iso = {TERMÉSZET VILÁGA},
	journal = {TERMÉSZET VILÁGA},
	volume = {146},
	unique-id = {2930170},
	issn = {0040-3717},
	year = {2015},
	pages = {209-210}
}

@article{MTMT:2984167,
	title = {Towards long term cultivation of Drosophila wing imaginal discs in vitro},
	url = {https://m2.mtmt.hu/api/publication/2984167},
	author = {Handke, B and Szabad, János and Lidsky, PV and Hafen, E and Lehner, CF},
	doi = {10.1371/journal.pone.0107333},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {9},
	unique-id = {2984167},
	issn = {1932-6203},
	abstract = {The wing imaginal disc of Drosophila melanogaster is a prominent experimental system for research on control of cell growth, proliferation and death, as well as on pattern formation and morphogenesis during organogenesis. The precise genetic methodology applicable in this system has facilitated conceptual advances of fundamental importance for developmental biology. Experimental accessibility and versatility would gain further if long term development of wing imaginal discs could be studied also in vitro. For example, culture systems would allow live imaging with maximal temporal and spatial resolution. However, as clearly demonstrated here, standard culture methods result in a rapid cell proliferation arrest within hours of cultivation of dissected wing imaginal discs. Analysis with established markers for cells in S- and M phase, as well as with RGB cell cycle tracker, a novel reporter transgene, revealed that in vitro cultivation interferes with cell cycle progression throughout interphase and not just exclusively during G1. Moreover, quantification of EGFP expression from an inducible transgene revealed rapid adverse effects of disc culture on basic cellular functions beyond cell cycle progression. Disc transplantation experiments confirmed that these detrimental consequences do not reflect fatal damage of imaginal discs during isolation, arguing clearly for a medium insufficiency. Alternative culture media were evaluated, including hemolymph, which surrounds imaginal discs during growth in situ. But isolated larval hemolymph was found to be even less adequate than current culture media, presumably as a result of conversion processes during hemolymph isolation or disc culture. The significance of prominent growth-regulating pathways during disc culture was analyzed, as well as effects of insulin and disc co-culture with larval tissues as potential sources of endocrine factors. Based on our analyses, we developed a culture protocol that prolongs cell proliferation in cultured discs.},
	keywords = {Animals; metabolism; GENETICS; animal; growth, development and aging; culture medium; gene expression regulation; larva; developmental biology; in vitro study; Cell Cycle; Gene Expression Regulation, Developmental; Drosophila melanogaster; Culture Media; Coculture Techniques; MORPHOGENESIS; coculture; Forelimb; Drosophila Proteins; Hemolymph; Wing; Drosophila protein; imaginal disc; IMAGINAL DISCS; procedures; In Vitro Techniques},
	year = {2014},
	eissn = {1932-6203}
}

@article{MTMT:2392076,
	title = {Assaying benzene, a parguet varnish and a synthetic thinner with respect to induction of in vivo chromosome loss in wing primordial cells of Drosophila},
	url = {https://m2.mtmt.hu/api/publication/2392076},
	author = {Soós, István and Szabad, János},
	doi = {10.1016/j.mrgentox.2013.11.007},
	journal-iso = {MUTAT RES-GEN TOX EN},
	journal = {MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS},
	volume = {763},
	unique-id = {2392076},
	issn = {1383-5718},
	year = {2014},
	eissn = {1879-3592},
	pages = {18-22}
}