@article{MTMT:34763930, title = {Real-Time Cone-Growth Model for Determination of Pharmaceutical Powder Flow Properties}, url = {https://m2.mtmt.hu/api/publication/34763930}, author = {Farkas, Gyula and Nagy, Sándor and Dévay, Attila and Széchenyi, Aleksandar and Pál, Szilárd}, doi = {10.3390/pharmaceutics16030405}, journal-iso = {PHARMACEUTICS}, journal = {PHARMACEUTICS}, volume = {16}, unique-id = {34763930}, issn = {1999-4923}, abstract = {The flow properties of pellets or granules are crucial for further processing drug dosage forms. Optimal compression or filling of multiparticulate dosage forms into capsules is influenced by forces between discrete particles, which could be partially characterized by flow properties. Several techniques have been developed to examine flowability, including static and dynamic methods applying empirical studies and up-to-date chaos theory; however, the newest methods seem only to be powerful with the supplementation of empirical principles. Our experiments try to refine both the technique of analysis and the methods, by finding new, alternative ways. Our approach to the flowability measurements was to set up a dynamic time-dependent model that combined empirical observations and chaos theory on a geometrical basis, thus finding new characteristics regarding the flow properties of pellets and granules that could be relevant for drug developers. Our findings indicate that sphericity and particle size are the most significant factors influencing the flowability of pharmaceutical multiparticular preparations. Furthermore, this study confirms that integrating chaos theory and empirical observations in a time-dependent dynamic model provides a comprehensive understanding of particle flow behavior, pivotal for optimizing manufacturing processes.}, keywords = {Flow properties; flow time; flow curve; conical section; static angle of repose}, year = {2024}, eissn = {1999-4923}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:33806312, title = {A Facile Synthetic Approach toward Obtaining N-Doped Carbon Quantum Dots from Citric Acid and Amino Acids, and Their Application in Selective Detection of Fe(III) Ions}, url = {https://m2.mtmt.hu/api/publication/33806312}, author = {Šafranko, S. and Janđel, K. and Kovačević, M. and Stanković, A. and Dutour, Sikirić M. and Mandić, Š. and Széchenyi, Aleksandar and Glavaš, Obrovac L. and Leventić, M. and Strelec, I. and Aladić, K. and Jokić, S.}, doi = {10.3390/chemosensors11040205}, journal-iso = {CHEMOSENSORS}, journal = {CHEMOSENSORS}, volume = {11}, unique-id = {33806312}, year = {2023}, eissn = {2227-9040}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:33695774, title = {Development of the New Sensor Based on Functionalized Carbon Nanomaterials for Promethazine Hydrochloride Determination.}, url = {https://m2.mtmt.hu/api/publication/33695774}, author = {Samardžić, Mirela and Peršić, Mateja and Széchenyi, Aleksandar and Jozanović, Marija and Pukleš, Iva and Budetić, Mateja}, doi = {10.3390/s23052641}, journal-iso = {SENSORS-BASEL}, journal = {SENSORS}, volume = {23}, unique-id = {33695774}, abstract = {Promethazine hydrochloride (PM) is a widely used drug so its determination is important. Solid-contact potentiometric sensors could be an appropriate solution for that purpose due to their analytical properties. The aim of this research was to develop solid-contact sensor for potentiometric determination of PM. It had a liquid membrane containing hybrid sensing material based on functionalized carbon nanomaterials and PM ions. The membrane composition for the new PM sensor was optimized by varying different membrane plasticizers and the content of the sensing material. The plasticizer was selected based on calculations of Hansen solubility parameters (HSP) and experimental data. The best analytical performances were obtained using a sensor with 2-nitrophenyl phenyl ether (NPPE) as the plasticizer and 4% of the sensing material. It had a Nernstian slope (59.4 mV/decade of activity), a wide working range (6.2 × 10-7 M-5.0 × 10-3 M), a low limit of detection (1.5 × 10-7 M), fast response time (6 s), low signal drift (-1.2 mV/h), and good selectivity. The working pH range of the sensor was between 2 and 7. The new PM sensor was successfully used for accurate PM determination in a pure aqueous PM solution and pharmaceutical products. For that purpose, the Gran method and potentiometric titration were used.}, keywords = {POTENTIOMETRY; Solid-contact sensor; Promethazine hydrochloride}, year = {2023}, eissn = {1424-8220}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:32907495, title = {Influence of Aliphatic Chain Length on Structural, Thermal and Electrochemical Properties of n-alkylene Benzyl Alcohols : A Study of the Odd-Even Effect}, url = {https://m2.mtmt.hu/api/publication/32907495}, author = {Balić, Tomislav and Paurević, Marija and Počkaj, Marta and Medvidović-Kosanović, Martina and Goman, Dominik and Széchenyi, Aleksandar and Preisz, Zsolt and Kunsági-Máté, Sándor}, doi = {10.3390/molecules27123781}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {27}, unique-id = {32907495}, issn = {1420-3049}, abstract = {The century-old, well-known odd-even effect phenomenon is still a very attractive and intriguing topic in supramolecular and nano-scale organic chemistry. As a part of our continuous efforts in the study of supramolecular chemistry, we have prepared three novel aromatic alcohols (1,2-bis[2-(hydroxymethyl)phenoxy]butylene (Do4OH), 1,2-bis[2-(hydroxymethyl)phenoxy]pentylene (Do5OH) and 1,2-bis[2-(hydroxymethyl)phenoxy]hexylene (Do6OH)) and determined their crystal and molecular structures by single-crystal X-ray diffraction. In all compounds, two benzyl alcohol groups are linked by an aliphatic chain of different lengths (CH2)n; n = 4, 5 and 6. The major differences in the molecular structures were found in the overall planarity of the molecules and the conformation of the aliphatic chain. Molecules with an even number of CH2 groups tend to be planar with an all-trans conformation of the aliphatic chain, while the odd-numbered molecule is non-planar, with partial gauche conformation. A direct consequence of these structural differences is visible in the melting points-odd-numbered compounds of a particular series display systematically lower melting points. Crystal and molecular structures were additionally studied by the theoretical calculations and the melting points were correlated with packing density and the number of CH2 groups. The results have shown that the generally accepted rule, higher density = higher stability = higher melting point, could not be applied to these compounds. It was found that the denser packaging causes an increase in the percentage of repulsive H‧‧‧H interactions, thereby reducing the stability of the crystal, and consequently, the melting points. Another interesting consequence of different molecular structures is their electrochemical and antioxidative properties-a non-planar structure displays the highest oxidation peak of hydroxyl groups and moderate antioxidant activity.}, keywords = {crystal structures; odd-even effect; Aromatic alcohols; aliphatic chain; melting point deviation}, year = {2022}, eissn = {1420-3049}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:32819183, title = {Omicron : increased transmissibility and decreased pathogenicity}, url = {https://m2.mtmt.hu/api/publication/32819183}, author = {Bálint, Gábor and Vörös-Horváth, Barbara and Széchenyi, Aleksandar}, doi = {10.1038/s41392-022-01009-8}, journal-iso = {SIGNAL TRANSDUCT TAR}, journal = {SIGNAL TRANSDUCTION AND TARGETED THERAPY}, volume = {7}, unique-id = {32819183}, issn = {2095-9907}, year = {2022}, eissn = {2059-3635}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:32843480, title = {A new sensor for direct potentiometric determination of thiabendazole in fruit peels using the Gran method}, url = {https://m2.mtmt.hu/api/publication/32843480}, author = {Budetić, Mateja and Samardžić, Mirela and Bubnjar, Karlo and Dandić, Andrea and Živković, Pavo and Széchenyi, Aleksandar and Kiss, László}, doi = {10.1016/j.foodchem.2022.133290}, journal-iso = {FOOD CHEM}, journal = {FOOD CHEMISTRY}, volume = {392}, unique-id = {32843480}, issn = {0308-8146}, year = {2022}, eissn = {1873-7072}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:32894547, title = {A New, MWCNT-Based, Solid-State Thiabendazole-Selective Sensor}, url = {https://m2.mtmt.hu/api/publication/32894547}, author = {Dandic, Andrea and Novak, Ivana and Jozanović, Marija and Pukleš, Iva and Széchenyi, Aleksandar and Budetic, Mateja and Samardzic, Mirela}, doi = {10.3390/s22103785}, journal-iso = {SENSORS-BASEL}, journal = {SENSORS}, volume = {22}, unique-id = {32894547}, abstract = {Direct potentiometric measurements using solid-state sensors have a great potential for thiabendazole (TBZ) determination, considering simplicity, accuracy, and low cost. Modifying the sensing material of the sensor with multi-walled carbon nanotubes (MWCNTs) leads to improved analytical properties of the sensor. In this study, a new potentiometric solid-state sensor for TBZ determination, based on MWCNTs modified with a sulfate group, and TBZ ion as sensing material was developed. The sensor exhibited a Nernstian response for TBZ (60.4 mV/decade of activity) in a working range between 8.6 x 10(-7) and 1.0 x 10(-3) M. The detection limit for TBZ was 6.2 x 10(-7) M. The response time of the sensor for TBZ was 8 s, and its signal drift was only 1.7 mV/h. The new sensor is applicable for direct potentiometric determination of TBZ in complex real samples, such as fruit peel. The accuracy of TBZ determination is confirmed using the standard addition method.}, keywords = {SAMPLES; CARBON NANOTUBES; Electrodes; IMMUNOASSAY; Chemistry, Analytical; Engineering, Electrical & Electronic; Thiabendazole; solid-state sensor; FUNGICIDE THIABENDAZOLE}, year = {2022}, eissn = {1424-8220}, orcid-numbers = {Jozanović, Marija/0000-0002-9509-8105; Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:32593111, title = {Review of characteristics and analytical methods for determination of indomethacin}, url = {https://m2.mtmt.hu/api/publication/32593111}, author = {Dandić, Andrea and Rajkovača, Katarina and Jozanović, Marija and Pukleš, Iva and Széchenyi, Aleksandar and Budetić, Mateja and Samardžić, Mirela}, doi = {10.1515/revac-2022-0032}, journal-iso = {REV ANAL CHEM}, journal = {REVIEWS IN ANALYTICAL CHEMISTRY}, volume = {41}, unique-id = {32593111}, issn = {0793-0135}, year = {2022}, eissn = {2191-0189}, pages = {34-62}, orcid-numbers = {Jozanović, Marija/0000-0002-9509-8105; Széchenyi, Aleksandar/0000-0001-9207-2551} } @inproceedings{MTMT:32733052, title = {Bioimpedancia mérő plate fejlesztése hipoxiás és hiperoxiás állapotok vizsgálatára sejtkultúrákban}, url = {https://m2.mtmt.hu/api/publication/32733052}, author = {Filotás, Nóra and Helt, Réka and Hencz, Alexandra Júlia and Tenzlinger, Kristóf and Odry, Ákos and Odry, Péter and Széchenyi, Aleksandar and Karádi, Zoltán György and Tóth, Attila and Vizvári, Zoltán Ákos and Pál, József}, booktitle = {Orvosbiológiai kérdések - multidiszciplináris, bioimpedancia alapú válaszok}, unique-id = {32733052}, year = {2022}, pages = {104-114}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @inproceedings{MTMT:32733167, title = {Grafén és indium-ón-oxid elektródák összehasonlítása alacsony frekvenciás elektromos impedancia spektroszkópia mérésekkel}, url = {https://m2.mtmt.hu/api/publication/32733167}, author = {Hencz, Alexandra Júlia and Szilágyi, Gábor and Győrfi, Nina Rubina and Tenzlinger, Kristóf and Odry, Ákos and Odry, Péter and Széchenyi, Aleksandar and Karádi, Zoltán and Tóth, Attila and Vizvári, Zoltán Ákos and Pál, József}, booktitle = {Orvosbiológiai kérdések - multidiszciplináris, bioimpedancia alapú válaszok}, unique-id = {32733167}, year = {2022}, pages = {115-123}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @inproceedings{MTMT:32733333, title = {Saját fejlesztésű bioimpedancia mérőelektród előkészítése és validálása tumorsejtek mérésére}, url = {https://m2.mtmt.hu/api/publication/32733333}, author = {Nádasdi, Lili and Maczkó, Gergő and Győrfi, Nina Rubina and Tenzlinger, Kristóf and Odry, Ákos and Odry, Péter and Széchenyi, Aleksandar and Karádi, Zoltán and Tóth, Attila and Pál, József and Vizvári, Zoltán Ákos}, booktitle = {Orvosbiológiai kérdések - multidiszciplináris, bioimpedancia alapú válaszok}, unique-id = {32733333}, year = {2022}, pages = {124-133}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:32907484, title = {Cocrystals of tuberculosis antibiotics : Challenges and missed opportunities}, url = {https://m2.mtmt.hu/api/publication/32907484}, author = {Salem, Ala' and Khanfar, Esam and Nagy, Sándor and Széchenyi, Aleksandar}, doi = {10.1016/j.ijpharm.2022.121924}, journal-iso = {INT J PHARM}, journal = {INTERNATIONAL JOURNAL OF PHARMACEUTICS}, volume = {623}, unique-id = {32907484}, issn = {0378-5173}, abstract = {Cocrystals have been extensively used to improve the physicochemical properties and bioavailability of active pharmaceutical ingredients. Cocrystals of anti-tuberculosis medications are among those commonly reported. This review provides a summary of the tuberculosis antibiotic cocrystals reported in the literature, providing the main results on current tuberculosis medications utilized in cocrystals. Moreover, anti-tuberculosis cocrystals limitations and advantages are described, including evidence for enhanced solubility, stability and effect. Opportunities to enhance anti-tuberculosis medications and fixed dose combinations using cocrystals are given. Several cocrystal pairs are suggested to enhance the effectiveness of anti-tuberculosis drugs.}, keywords = {Solubility; Cocrystal; multidrug-resistant; Anti-tuberculosis; Drug-drug cocrystal}, year = {2022}, eissn = {1873-3476}, orcid-numbers = {Khanfar, Esam/0000-0001-5260-7937; Széchenyi, Aleksandar/0000-0001-9207-2551} } @inproceedings{MTMT:32733357, title = {Grafénnel bevont mérőeszköz fejlesztése “sötét” neuronok vizsgálatára elektromos impedancia (EIS) mérés segítségével}, url = {https://m2.mtmt.hu/api/publication/32733357}, author = {Varga, Réka and Berta, Kiara and Győrfi, Nina Rubina and Tenzlinger, Kristóf and Odry, Ákos and Odry, Péter and Széchenyi, Aleksandar and Karádi, Zoltán and Tóth, Attila and Pál, József and Vizvári, Zoltán Ákos}, booktitle = {Orvosbiológiai kérdések - multidiszciplináris, bioimpedancia alapú válaszok}, unique-id = {32733357}, year = {2022}, pages = {134-143}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:32623813, title = {Preparation and Characterization of ACE2 Receptor Inhibitor-Loaded Chitosan Hydrogels for Nasal Formulation to Reduce the Risk of COVID-19 Viral Infection}, url = {https://m2.mtmt.hu/api/publication/32623813}, author = {Vörös-Horváth, Barbara and Zivkovic, Pavo and Bánfai, Krisztina and Bovári-Biri, Judit and Pongrácz, Judit and Bálint, Gábor and Pál, Szilárd and Széchenyi, Aleksandar}, doi = {10.1021/acsomega.1c05149}, journal-iso = {ACS OMEGA}, journal = {ACS OMEGA}, volume = {7}, unique-id = {32623813}, issn = {2470-1343}, abstract = {The COVID-19 virus is spread by pulmonary droplets. Its high infectivity is caused by the high-affinity binding of the viral spike protein to the ACE2 receptors on the surface of respiratory epithelial cell membranes. The proper hydration of nasal mucosa plays an essential role in defense of bacterial and viral infections. Therefore, a nasal formulation, which can moisture the nasal mucosa and contains the ACE2 receptor inhibitor, can reduce the risk of COVID-19 infection. This article presents a systematic study of the preparation of chitosan hydrogels with dicarboxylic acids (malic and glutaric acid) and their detailed characterization (Fourier transform infrared spectroscopy, deter-mination of cross-linking efficiency, rheological studies, thermal analysis, and swelling kinetics). The results confirm that chemically cross-linked chitosan hydrogels can be synthesized using malic or glutaric acid without additives or catalysts. The adsorption capacity of hydrogels for three different ACE2 inhibitors, as APIs, has also been investigated. The API content of hydrogels and their mucoadhesive property can provide an excellent basis to use the hydrogels for the development of a nasal formulation in order to reduce the risk of SARS-CoV 2 infection.}, keywords = {DERIVATIVES; PROTEIN; antiviral activity; DRUG-DELIVERY; Chitin; Inserts; SARS coronavirus}, year = {2022}, eissn = {2470-1343}, pages = {3240-3253}, orcid-numbers = {Pongrácz, Judit/0000-0002-0278-5556; Széchenyi, Aleksandar/0000-0001-9207-2551} } @inproceedings{MTMT:32120818, title = {The development of graphene coated measuring plate for the investigation of “dark” neurons with electrical impedance spectrum (EIS) measurement}, url = {https://m2.mtmt.hu/api/publication/32120818}, author = {Berta, Kiara and Varga, Reka and Győrfi, Nina Rubina and Tenzlinger, Kristof and Odry, Ákos and Odry, Péter and Széchenyi, Aleksandar and Karádi, Zoltán György and Tóth, Attila and Vizvári, Zoltán Ákos and Pál, József}, booktitle = {15th IEEE International Symposium on Applied Computational Intelligence and Informatics SACI 2021}, doi = {10.1109/SACI51354.2021.9465541}, unique-id = {32120818}, year = {2021}, pages = {000159-000164}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @inproceedings{MTMT:32120790, title = {Development of a Bioimpedance Measuring Plate for the Study of Hypoxic and Hyperoxic Conditions in Cell Cultures}, url = {https://m2.mtmt.hu/api/publication/32120790}, author = {Filotas, Nora and Helt, Reka and Hencz, Alexandra Júlia and Tenzlinger, Kristof and Odry, Ákos and Odry, Péter and Karádi, Zoltán György and Vizvári, Zoltán Ákos and Tóth, Attila and Győrfi, Nina Rubina and Széchenyi, Aleksandar and Pál, József}, booktitle = {15th IEEE International Symposium on Applied Computational Intelligence and Informatics SACI 2021}, doi = {10.1109/SACI51354.2021.9465616}, unique-id = {32120790}, year = {2021}, pages = {153-158}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @inproceedings{MTMT:32120814, title = {Comparative electrical impedance spectroscopy study of graphene and indium tin oxide electrodes during low frequency measurements}, url = {https://m2.mtmt.hu/api/publication/32120814}, author = {Hencz, Alexandra Júlia and Szilagyi, Gabor and Győrfi, Nina Rubina and Tenzlinger, Kristof and Széchenyi, Aleksandar and Odry, Ákos and Odry, Péter and Karádi, Zoltán György and Vizvári, Zoltán Ákos and Tóth, Attila and Pál, József}, booktitle = {15th IEEE International Symposium on Applied Computational Intelligence and Informatics SACI 2021}, doi = {10.1109/SACI51354.2021.9465546}, unique-id = {32120814}, year = {2021}, pages = {000147-000152}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:32152322, title = {Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation}, url = {https://m2.mtmt.hu/api/publication/32152322}, author = {Jukić, Ivana and Kolobarić, Nikolina and Stupin, Ana and Matić, Anita and Kozina, Nataša and Mihaljević, Zrinka and Mihalj, Martina and Šušnjara, Petar and Stupin, Marko and Ćurić, Željka Breškić and Selthofer-Relatić, Kristina and Kibel, Aleksandar and Lukinac, Anamarija and Kolar, Luka and Kralik, Gordana and Kralik, Zlata and Széchenyi, Aleksandar and Jozanović, Marija and Galović, Olivera and Medvidović-Kosanović, Martina and Drenjančević, Ines}, doi = {10.3390/antiox10071037}, journal-iso = {ANTIOXIDANTS-BASEL}, journal = {ANTIOXIDANTS}, volume = {10}, unique-id = {32152322}, year = {2021}, eissn = {2076-3921}, orcid-numbers = {Stupin, Ana/0000-0002-7446-0021; Matić, Anita/0000-0002-3374-8512; Mihaljević, Zrinka/0000-0002-6631-071X; Mihalj, Martina/0000-0002-5734-5849; Selthofer-Relatić, Kristina/0000-0002-9890-6489; Kralik, Zlata/0000-0001-9056-9564; Széchenyi, Aleksandar/0000-0001-9207-2551; Jozanović, Marija/0000-0002-9509-8105; Medvidović-Kosanović, Martina/0000-0002-9887-9169} } @inproceedings{MTMT:32120811, title = {Preparation and Validation of Self-developed Bioimpedance Electrode Array for Measurement of Tumor Cells}, url = {https://m2.mtmt.hu/api/publication/32120811}, author = {Nadasdi, Lili and Maczko, Gergo and Győrfi, Nina Rubina and Tenzlinger, Kristof and Odry, Ákos and Odry, Péter and Széchenyi, Aleksandar and Karádi, Zoltán György and Pál, József and Tóth, Attila and Vizvári, Zoltán Ákos}, booktitle = {15th IEEE International Symposium on Applied Computational Intelligence and Informatics SACI 2021}, doi = {10.1109/SACI51354.2021.9465598}, unique-id = {32120811}, year = {2021}, pages = {000129-000134}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:32188208, title = {Preparation of Multifunctional N-Doped Carbon Quantum Dots from Citrus clementina Peel: Investigating Targeted Pharmacological Activities and the Potential Application for Fe3+ Sensing}, url = {https://m2.mtmt.hu/api/publication/32188208}, author = {Šafranko, Silvija and Stanković, Anamarija and Hajra, Sugato and Kim, Hoe-Joon and Strelec, Ivica and Dutour-Sikirić, Maja and Weber, Igor and Bosnar, Maja H. and Grbčić, Petra and Pavelić, Sandra K. and Széchenyi, Aleksandar and Mishra, Yogendra K. and Jerković, Igor and Jokić, Stela}, doi = {10.3390/ph14090857}, journal-iso = {PHARMACEUTICALS-BASE}, journal = {PHARMACEUTICALS}, volume = {14}, unique-id = {32188208}, abstract = {Carbon quantum dots (CQDs) have recently emerged as innovative theranostic nanomaterials, enabling fast and effective diagnosis and treatment. In this study, a facile hydrothermal approach for N-doped biomass-derived CQDs preparation from Citrus clementina peel and amino acids glycine (Gly) and arginine (Arg) has been presented. The gradual increase in the N-dopant (amino acids) nitrogen content increased the quantum yield of synthesized CQDs. The prepared CQDs exhibited good biocompatibility, stability in aqueous, and high ionic strength media, similar optical properties, while differences were observed regarding the structural and chemical diversity, and biological and antioxidant activity. The antiproliferative effect of CQD@Gly against pancreatic cancer cell lines (CFPAC-1) was observed. At the same time, CQD@Arg has demonstrated the highest quantum yield and antioxidant activity by DPPH scavenging radical method of 81.39 ± 0.39% and has been further used for the ion sensing and cellular imaging of cancer cells. The obtained results have demonstrated selective response toward Fe3+ detection, with linear response ranging from 7.0 µmol dm−3 to 50.0 µmol dm−3 with R2 = 0.9931 and limit of detection (LOD) of 4.57 ± 0.27 µmol dm−3. This research could be a good example of sustainable biomass waste utilization with potential for biomedical analysis and ion sensing applications.}, keywords = {biocompatibility; CARBON QUANTUM DOTS; N-doping; Citrus waste; Fe3+ detection}, year = {2021}, eissn = {1424-8247}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} }