1.
Orgován, Zoltán ; Péczka, Nikolett ; Petri, László ; Ábrányi-Balogh, Péter ; Ranđelović, Ivan ; Tóth, Szilárd ; Szakács, Gergely ; Nyíri, Kinga ; Vértessy, Beáta ; Pálfy, Gyula et al.
Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 250 Paper: 115212 (2023)
DOI Scopus PubMed Egyéb URL
Publication:33647485 Published Core Journal Article (Article ) Scientific
Article (Journal Article) | Scientific[33647485] [Approved]
2.
Kiss-Szemán, Anna J. ; Takács, Luca ; Orgován, Zoltán ; Stráner, Pál ; Jákli, Imre ; Schlosser, Gitta ; Masiulis, Simonas ; Harmat, Veronika ; Menyhárd, Dóra K. ; Perczel, András
A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase–meropenem complex
CHEMICAL SCIENCE 13 : 48 pp. 14264-14276. , 13 p. (2022)
DOI WoS REAL Scopus PubMed Egyéb URL
Publication:33307131 Validated Core Citing Journal Article (Article ) Scientific
Article (Journal Article) | Scientific[33307131] [Validated]
3.
Peczka, Nikolett ; Orgovan, Zoltan ; Abranyi-Balogh, Peter ; Keseru, Gyorgy Miklos ✉
Electrophilic warheads in covalent drug discovery: an overview
EXPERT OPINION ON DRUG DISCOVERY 17 pp. 413-422. , 10 p. (2022)
DOI ISSN: 1746-045X WoS Scopus PubMed
Publication:32756662 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 3 | Independent citation: 3 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 3 | Number of citations in Scopus: 1 | WoS/Scopus assigned: 3 | Number of citations with DOI: 3
Article (Journal Article) | Scientific[32756662] [Validated]
All citations+mentions: 3, External citations: 3, Self citations: 0, Unhandled citations: 0
4.
Orgovan, Zoltan ; Ferenczy, Gyorgy G. ; Keseru, Gyorgy M. ✉
Allosteric Molecular Switches in Metabotropic Glutamate Receptors
CHEMMEDCHEM 16 : 1 pp. 81-93. , 14 p. (2021)
DOI WoS Scopus PubMed
Publication:31698584 Validated Core Citing Journal Article (Survey paper ) Scientific
Citing papers: 4 | Independent citation: 4 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 4 | Number of citations in Scopus: 3 | WoS/Scopus assigned: 4 | Number of citations with DOI: 4
Survey paper (Journal Article) | Scientific[31698584] [Validated]
All citations+mentions: 4, External citations: 4, Self citations: 0, Unhandled citations: 0
5.
Jójárt, Balázs ; Orgován, Zoltán* ; Márki, Árpád ; Pándy-Szekeres, Gáspár ; Ferenczy, György G. ; Keserű, György M. ✉
Allosteric activation of metabotropic glutamate receptor 5
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 38 : 9 pp. 2624-2632. , 10 p. (2020)
DOI WoS Scopus PubMed SZTE Publicatio
Publication:30834454 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 5 | Independent citation: 3 | Self citation: 2 | Unknown citation: 0 | Number of citations in WoS: 5 | Number of citations in Scopus: 5 | WoS/Scopus assigned: 5 | Number of citations with DOI: 5
Article (Journal Article) | Scientific[30834454] [Validated]
All citations+mentions: 5, External citations: 3, Self citations: 2, Unhandled citations: 0
6.
Menyhard, Dora K. ; Palfy, Gyula ; Orgovan, Zoltan ; Vida, Istvan ; Keseru, Gyorgy M. ✉ ; Perczel, Andras ✉
Structural impact of GTP binding on downstream KRAS signaling
CHEMICAL SCIENCE 11 : 34 pp. 9272-9289. , 18 p. (2020)
DOI WoS PubMed Egyéb URL
Publication:31605838 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 12 | Independent citation: 10 | Self citation: 2 | Unknown citation: 0 | Number of citations in WoS: 9 | Number of citations in Scopus: 5 | WoS/Scopus assigned: 9 | Number of citations with DOI: 11
Article (Journal Article) | Scientific[31605838] [Validated]
All citations+mentions: 12, External citations: 10, Self citations: 2, Unhandled citations: 0
7.
Orgován, Z. ; Keserű, G.M. ✉
Small molecule inhibitors of RAS proteins with oncogenic mutations
CANCER AND METASTASIS REVIEWS 39 pp. 1107-1126. , 20 p. (2020)
DOI WoS Scopus
Publication:31473660 Validated Core Citing Journal Article (Survey paper ) Scientific
Citing papers: 10 | Independent citation: 9 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 10 | Number of citations in Scopus: 8 | WoS/Scopus assigned: 10 | Number of citations with DOI: 10 (Not published: 1)
Survey paper (Journal Article) | Scientific[31473660] [Validated]
All citations+mentions: 10, External citations: 9, Self citations: 1, Unhandled citations: 0
8.
Szabó, György ; Kolok, Sándor ; Orgován, Zoltán ; Vastag, Mónika ; Béni, Zoltán ; Kóti, János ; Sághy, Katalin ; Lévay, György I. ; Greiner, István ; Keserű, György M. ✉
Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs)
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 186 Paper: 111881 (2020)
DOI WoS Scopus Egyéb URL
Publication:30928052 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 2 | Independent citation: 1 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 2 | Number of citations in Scopus: 1 | WoS/Scopus assigned: 2 | Number of citations with DOI: 2
Article (Journal Article) | Scientific[30928052] [Validated]
All citations+mentions: 2, External citations: 1, Self citations: 1, Unhandled citations: 0
9.
Christopher, John A. ✉ ; Orgován, Zoltán ; Congreve, Miles ; Doré, Andrew S. ; Errey, James C. ; Marshall, Fiona H. ; Mason, Jonathan S. ; Okrasa, Krzysztof ; Rucktooa, Prakash ; Serrano-Vega, Maria J. et al.
Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu 5 ) X-ray Structures
JOURNAL OF MEDICINAL CHEMISTRY 62 : 1 pp. 207-222. , 16 p. (2019)
DOI WoS Scopus PubMed Egyéb URL
Publication:30334026 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 42 | Independent citation: 35 | Self citation: 7 | Unknown citation: 0 | Number of citations in WoS: 42 | Number of citations in Scopus: 29 | WoS/Scopus assigned: 42 | Number of citations with DOI: 42
Article (Journal Article) | Scientific[30334026] [Validated]
All citations+mentions: 42, External citations: 35, Self citations: 7, Unhandled citations: 0
10.
Nyíri, Kinga ; Koppány, Gergely ; Pálfy, Gyula ; Vida, István ; Tóth, Szilárd ; Orgován, Zoltán ; Ivan, Ranđelović ; Baranyi, Marcell ; Molnár, Eszter ; Keserű, György Miklós et al.
Allélspecifikus inhibitorok nyomában: a RASopátia konzorcium célpontjában a KRAS fehérje onkogén mutációi
MAGYAR ONKOLÓGIA 63 : 4 pp. 310-323. , 10 p. (2019)
Scopus PubMed Egyéb URL Matarka MOB
Locked Publication:31038395 Validated Core Citing Journal Article (Article ) Scientific
Article (Journal Article) | Scientific[31038395] [Validated]
11.
Orgován, Zoltán ; Ferenczy, György G. ; Keserű, György M. ✉
Fragment-Based Approaches for Allosteric Metabotropic Glutamate Receptor (mGluR) Modulators
CURRENT TOPICS IN MEDICINAL CHEMISTRY 19 : 19 pp. 1768-1781. , 14 p. (2019)
DOI WoS Scopus PubMed
Publication:30834430 Validated Core Citing Journal Article (Survey paper ) Scientific
Citing papers: 3 | Independent citation: 2 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 3 | Number of citations in Scopus: 1 | WoS/Scopus assigned: 3 | Number of citations with DOI: 3 (Not published: 2)
Survey paper (Journal Article) | Scientific[30834430] [Validated]
All citations+mentions: 3, External citations: 2, Self citations: 1, Unhandled citations: 0
12.
Orgován, Zoltán ; Ferenczy, György G. ; Keserű, György M. ✉
The role of water and protein flexibility in the structure-based virtual screening of allosteric GPCR modulators: an mGlu5 receptor case study
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 33 : 9 pp. 787-797. , 11 p. (2019)
DOI WoS Scopus PubMed
Publication:30834424 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 5 | Independent citation: 5 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 5 | Number of citations in Scopus: 3 | WoS/Scopus assigned: 5 | Number of citations with DOI: 5
Article (Journal Article) | Scientific[30834424] [Validated]
All citations+mentions: 5, External citations: 5, Self citations: 0, Unhandled citations: 0
13.
Orgován, Zoltán ; Ferenczy, György G ; Steinbrecher, Thomas ; Szilágyi, Bence ; Bajusz, Dávid ; Keserű, György M ✉
Validation of tautomeric and protomeric binding modes by free energy calculations. A case study for the structure based optimization of d-amino acid oxidase inhibitors
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 32 : 2 pp. 331-345. , 15 p. (2018)
DOI WoS Scopus PubMed
Publication:3333356 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 7 | Independent citation: 4 | Self citation: 3 | Unknown citation: 0 | Number of citations in WoS: 7 | Number of citations in Scopus: 5 | WoS/Scopus assigned: 7 | Number of citations with DOI: 7
Article (Journal Article) | Scientific[3333356] [Validated]
All citations+mentions: 7, External citations: 4, Self citations: 3, Unhandled citations: 0
14.
Galambos, J ; Bielik, A ; Wágner, G ; Domány, G ; Kóti, J ; Béni, Z ; Szigetvári, Á ; Sánta, Z ; Orgován, Z ; Bobok, A et al.
Discovery of 4-amino-3-arylsulfoquinolines, a novel non-acetylenic chemotype of metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulators
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 133 pp. 240-254. , 15 p. (2017)
DOI Scopus
Publication:3291826 Validated Core Journal Article (Article ) Scientific
Citing papers: 3 | Independent citation: 2 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 3 | Number of citations in Scopus: 3 | WoS/Scopus assigned: 3 | Number of citations with DOI: 3
Article (Journal Article) | Scientific[3291826] [Validated]
All citations+mentions: 3, External citations: 2, Self citations: 1, Unhandled citations: 0
15.
Galambos, J ; Bielik, A ; Krasavin, M ; Orgován, Z ; Domány, G ; Nógrádi, K ; Wágner, G ; Balogh, GT ; Béni, Z ; Kóti, J et al.
Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications
JOURNAL OF MEDICINAL CHEMISTRY 60 : 6 pp. 2470-2484. , 15 p. (2017)
DOI WoS Scopus
Locked Publication:3291825 Admin approved Core Citing Journal Article (Article ) Scientific
Citing papers: 18 | Independent citation: 14 | Self citation: 4 | Unknown citation: 0 | Number of citations in WoS: 18 | Number of citations in Scopus: 16 | WoS/Scopus assigned: 18 | Number of citations with DOI: 18
Article (Journal Article) | Scientific[3291825] [Admin approved]
All citations+mentions: 18, External citations: 14, Self citations: 4, Unhandled citations: 0
16.
D K, Menyhárd ; Z, Orgován ; Z, Szeltner ; I, Szamosi ; V, Harmat
Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 71 pp. 461-472. , 12 p. (2015)
DOI REAL WoS Scopus PubMed
Publication:2832195 Admin approved Core Citing Journal Article (Article ) Scientific
Citing papers: 9 | Independent citation: 7 | Self citation: 2 | Unknown citation: 0 | Number of citations in WoS: 9 | Number of citations in Scopus: 9 | WoS/Scopus assigned: 9 | Number of citations with DOI: 9
Article (Journal Article) | Scientific[2832195] [Admin approved]
All citations+mentions: 9, External citations: 7, Self citations: 2, Unhandled citations: 0
2023-03-25 21:55