1.
Ábrányi-Balogh, Péter ; Bajusz, Dávid* ; Orgován, Zoltán* ; Keeley, Aaron B. ; Petri, László ; Péczka, Nikolett ; Szalai, Tibor Viktor ; Pálfy, Gyula ; Gadanecz, Márton ; Grant, Emma K. et al.
Mapping protein binding sites by photoreactive fragment pharmacophores
COMMUNICATIONS CHEMISTRY 7 : 1 Paper: 168 , 13 p. (2024)
DOI WoS Scopus PubMed Other URL
Publication:35160281 Validated Core Citing Journal Article (Article ) Scientific
Article (Journal Article) | Scientific[35160281] [Validated]
2.
Keeley, Aaron B. ; Kopranovic, Aleksandra ; Di Lorenzo, Vincenzo ; Ábrányi-Balogh, Péter ; Jänsch, Niklas ; Lai, Linh N. ; Petri, László ; Orgován, Zoltán ; Pölöske, Daniel ; Orlova, Anna et al.
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY 67 : 1 pp. 572-585. , 14 p. (2024)
DOI WoS Scopus PubMed Other URL
Publication:34445373 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 3 | Independent citation: 2 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 3 | Number of citations in Scopus: 2 | WoS/Scopus assigned: 3 | Number of citations with DOI: 3
Article (Journal Article) | Scientific[34445373] [Validated]
All citations+mentions: 3, External citations: 2, Self citations: 1, Unhandled citations: 0
3.
Péczka, Nikolett ; Ranđelović, Ivan ; Orgován, Zoltán ; Csorba, Noémi ; Egyed, Attila ; Petri, László ; Ábrányi-Balogh, Péter ; Gadanecz, Márton ; Perczel, András ; Tóvári, József et al.
Contribution of Noncovalent Recognition and Reactivity to the Optimization of Covalent Inhibitors : A Case Study on KRasG12C
ACS CHEMICAL BIOLOGY 19 : 8 pp. 1743-1756. , 14 p. (2024)
DOI WoS Scopus PubMed
Publication:35134356 Validated Core Citing Journal Article (Article ) Scientific
Article (Journal Article) | Scientific[35134356] [Validated]
4.
Wéber, Edit ; Ábrányi-Balogh, Péter* ; Martinek, Tamas A. ; Nagymihály, Bence ; Menyhárd, Dóra Karancsiné ; Péczka, Nikolett ; Gadanecz, Márton ; Schlosser, Gitta ; Orgován, Zoltán ; Bogár, Ferenc et al.
Target‐templated Construction of Functional Proteomimetics Using Photo‐foldamer Libraries
ANGEWANDTE CHEMIE Paper: e202410435 (2024)
DOI Other URL
Publication:35427664 Published Core Journal Article (Article ) Scientific
Article (Journal Article) | Scientific[35427664] [Approved]
5.
Orgován, Zoltán
Computational investigation of the allosteric modulation of metabotropic glutamate receptor 5 163 p.
Budapest University of Technology and Economics, Budapesti Műszaki és Gazdaságtudományi Egyetem, Oláh György Doktori Iskola, Keserű György Miklós Accepted: 2023 Published/defended: 2023
Műegyetem Digitális Archívum ODT védés
Publication:34738155 Published Core Thesis (PhD ) Scientific
PhD (Thesis) | Scientific[34738155] [Approved]
6.
Orgován, Zoltán ; Péczka, Nikolett* ; Petri, László ; Ábrányi-Balogh, Péter ; Ranđelović, Ivan ; Tóth, Szilárd ; Szakács, Gergely ; Nyíri, Kinga ; Vértessy, Beáta ; Pálfy, Gyula et al.
Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 250 Paper: 115212 , 7 p. (2023)
DOI WoS Scopus PubMed Other URL
Locked Publication:33647485 Published Core Citing Journal Article (Article ) Scientific
Citing papers: 2 | Independent citation: 1 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 1 | Number of citations in Scopus: 2 | WoS/Scopus assigned: 2 | Number of citations with DOI: 2
Article (Journal Article) | Scientific[33647485] [Approved]
All citations+mentions: 2, External citations: 1, Self citations: 1, Unhandled citations: 0
7.
Kiss-Szemán, Anna J. ; Takács, Luca ; Orgován, Zoltán ; Stráner, Pál ; Jákli, Imre ; Schlosser, Gitta ; Masiulis, Simonas ; Harmat, Veronika ; Menyhárd, Dóra K. ; Perczel, András
A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase–meropenem complex
CHEMICAL SCIENCE 13 : 48 pp. 14264-14276. , 13 p. (2022)
DOI WoS REAL Scopus PubMed Other URL
Publication:33307131 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 2 | Independent citation: 2 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 2 | Number of citations in Scopus: 2 | WoS/Scopus assigned: 2 | Number of citations with DOI: 2
Article (Journal Article) | Scientific[33307131] [Validated]
All citations+mentions: 2, External citations: 2, Self citations: 0, Unhandled citations: 0
8.
Peczka, Nikolett ; Orgovan, Zoltan ; Abranyi-Balogh, Peter ; Keseru, Gyorgy Miklos ✉
Electrophilic warheads in covalent drug discovery: an overview
EXPERT OPINION ON DRUG DISCOVERY 17 pp. 413-422. , 10 p. (2022)
DOI ISSN: 1746-045X WoS Scopus PubMed
Publication:32756662 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 35 | Independent citation: 32 | Self citation: 3 | Unknown citation: 0 | Number of citations in WoS: 35 | Number of citations in Scopus: 15 | WoS/Scopus assigned: 35 | Number of citations with DOI: 35
Article (Journal Article) | Scientific[32756662] [Validated]
All citations+mentions: 35, External citations: 32, Self citations: 3, Unhandled citations: 0
9.
Orgovan, Zoltan ; Ferenczy, Gyorgy G. ; Keseru, Gyorgy M. ✉
Allosteric Molecular Switches in Metabotropic Glutamate Receptors
CHEMMEDCHEM 16 : 1 pp. 81-93. , 14 p. (2021)
DOI WoS Scopus PubMed
Publication:31698584 Validated Core Citing Journal Article (Survey paper ) Scientific
Citing papers: 11 | Independent citation: 11 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 11 | Number of citations in Scopus: 5 | WoS/Scopus assigned: 11 | Number of citations with DOI: 11
Survey paper (Journal Article) | Scientific[31698584] [Validated]
All citations+mentions: 11, External citations: 11, Self citations: 0, Unhandled citations: 0
10.
Jójárt, Balázs ; Orgován, Zoltán* ; Márki, Árpád ; Pándy-Szekeres, Gáspár ; Ferenczy, György G. ; Keserű, György M. ✉
Allosteric activation of metabotropic glutamate receptor 5
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 38 : 9 pp. 2624-2632. , 10 p. (2020)
DOI WoS Scopus PubMed SZTE Publicatio
Publication:30834454 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 5 | Independent citation: 3 | Self citation: 2 | Unknown citation: 0 | Number of citations in WoS: 5 | Number of citations in Scopus: 5 | WoS/Scopus assigned: 5 | Number of citations with DOI: 5
Article (Journal Article) | Scientific[30834454] [Validated]
All citations+mentions: 5, External citations: 3, Self citations: 2, Unhandled citations: 0
11.
Menyhard, Dora K. ; Palfy, Gyula ; Orgovan, Zoltan ; Vida, Istvan ; Keseru, Gyorgy M. ✉ ; Perczel, Andras ✉
Structural impact of GTP binding on downstream KRAS signaling
CHEMICAL SCIENCE 11 : 34 pp. 9272-9289. , 18 p. (2020)
DOI WoS Scopus PubMed Other URL
Publication:31605838 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 25 | Independent citation: 22 | Self citation: 3 | Unknown citation: 0 | Number of citations in WoS: 21 | Number of citations in Scopus: 22 | WoS/Scopus assigned: 22 | Number of citations with DOI: 23
Article (Journal Article) | Scientific[31605838] [Validated]
All citations+mentions: 25, External citations: 22, Self citations: 3, Unhandled citations: 0
12.
Orgován, Z. ; Keserű, G.M. ✉
Small molecule inhibitors of RAS proteins with oncogenic mutations
CANCER AND METASTASIS REVIEWS 39 pp. 1107-1126. , 20 p. (2020)
DOI WoS Scopus
Publication:31473660 Validated Core Citing Journal Article (Survey paper ) Scientific
Citing papers: 17 | Independent citation: 13 | Self citation: 4 | Unknown citation: 0 | Number of citations in WoS: 17 | Number of citations in Scopus: 11 | WoS/Scopus assigned: 17 | Number of citations with DOI: 17
Survey paper (Journal Article) | Scientific[31473660] [Validated]
All citations+mentions: 17, External citations: 13, Self citations: 4, Unhandled citations: 0
13.
Szabó, György ; Kolok, Sándor ; Orgován, Zoltán ; Vastag, Mónika ; Béni, Zoltán ; Kóti, János ; Sághy, Katalin ; Lévay, György I. ; Greiner, István ; Keserű, György M. ✉
Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs)
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 186 Paper: 111881 (2020)
DOI WoS Scopus Other URL
Publication:30928052 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 5 | Independent citation: 4 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 5 | Number of citations in Scopus: 4 | WoS/Scopus assigned: 5 | Number of citations with DOI: 5
Article (Journal Article) | Scientific[30928052] [Validated]
All citations+mentions: 5, External citations: 4, Self citations: 1, Unhandled citations: 0
14.
Christopher, John A. ✉ ; Orgován, Zoltán ; Congreve, Miles ; Doré, Andrew S. ; Errey, James C. ; Marshall, Fiona H. ; Mason, Jonathan S. ; Okrasa, Krzysztof ; Rucktooa, Prakash ; Serrano-Vega, Maria J. et al.
Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu 5 ) X-ray Structures
JOURNAL OF MEDICINAL CHEMISTRY 62 : 1 pp. 207-222. , 16 p. (2019)
DOI WoS Scopus PubMed Other URL
Publication:30334026 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 54 | Independent citation: 47 | Self citation: 7 | Unknown citation: 0 | Number of citations in WoS: 54 | Number of citations in Scopus: 36 | WoS/Scopus assigned: 54 | Number of citations with DOI: 54
Article (Journal Article) | Scientific[30334026] [Validated]
All citations+mentions: 54, External citations: 47, Self citations: 7, Unhandled citations: 0
15.
Nyíri, Kinga ; Koppány, Gergely ; Pálfy, Gyula ; Vida, István ; Tóth, Szilárd ; Orgován, Zoltán ; Ivan, Ranđelović ; Baranyi, Marcell ; Molnár, Eszter ; Keserű, György Miklós et al.
Allélspecifikus inhibitorok nyomában: a RASopátia konzorcium célpontjában a KRAS fehérje onkogén mutációi
MAGYAR ONKOLÓGIA 63 : 4 pp. 310-323. , 10 p. (2019)
Scopus PubMed Other URL Matarka MOB
Locked Publication:31038395 Validated Core Citing Journal Article (Article ) Scientific
Article (Journal Article) | Scientific[31038395] [Validated]
16.
Orgován, Zoltán ; Ferenczy, György G. ; Keserű, György M. ✉
Fragment-Based Approaches for Allosteric Metabotropic Glutamate Receptor (mGluR) Modulators
CURRENT TOPICS IN MEDICINAL CHEMISTRY 19 : 19 pp. 1768-1781. , 14 p. (2019)
DOI WoS Scopus PubMed
Publication:30834430 Validated Core Citing Journal Article (Survey paper ) Scientific
Citing papers: 6 | Independent citation: 4 | Self citation: 2 | Unknown citation: 0 | Number of citations in WoS: 6 | Number of citations in Scopus: 3 | WoS/Scopus assigned: 6 | Number of citations with DOI: 6
Survey paper (Journal Article) | Scientific[30834430] [Validated]
All citations+mentions: 6, External citations: 4, Self citations: 2, Unhandled citations: 0
17.
Orgován, Zoltán ; Ferenczy, György G. ; Keserű, György M. ✉
The role of water and protein flexibility in the structure-based virtual screening of allosteric GPCR modulators: an mGlu5 receptor case study
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 33 : 9 pp. 787-797. , 11 p. (2019)
DOI WoS Scopus PubMed
Publication:30834424 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 6 | Independent citation: 6 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 6 | Number of citations in Scopus: 3 | WoS/Scopus assigned: 6 | Number of citations with DOI: 6
Article (Journal Article) | Scientific[30834424] [Validated]
All citations+mentions: 6, External citations: 6, Self citations: 0, Unhandled citations: 0
18.
Orgován, Zoltán ; Ferenczy, György G ; Steinbrecher, Thomas ; Szilágyi, Bence ; Bajusz, Dávid ; Keserű, György M ✉
Validation of tautomeric and protomeric binding modes by free energy calculations. A case study for the structure based optimization of d-amino acid oxidase inhibitors
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 32 : 2 pp. 331-345. , 15 p. (2018)
DOI WoS Scopus PubMed
Publication:3333356 Validated Core Citing Journal Article (Article ) Scientific
Citing papers: 8 | Independent citation: 5 | Self citation: 3 | Unknown citation: 0 | Number of citations in WoS: 8 | Number of citations in Scopus: 5 | WoS/Scopus assigned: 8 | Number of citations with DOI: 8
Article (Journal Article) | Scientific[3333356] [Validated]
All citations+mentions: 8, External citations: 5, Self citations: 3, Unhandled citations: 0
19.
Galambos, J ; Bielik, A ; Wágner, G ; Domány, G ; Kóti, J ; Béni, Z ; Szigetvári, Á ; Sánta, Z ; Orgován, Z ; Bobok, A et al.
Discovery of 4-amino-3-arylsulfoquinolines, a novel non-acetylenic chemotype of metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulators
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 133 pp. 240-254. , 15 p. (2017)
DOI Scopus
Publication:3291826 Validated Core Journal Article (Article ) Scientific
Citing papers: 3 | Independent citation: 2 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 3 | Number of citations in Scopus: 3 | WoS/Scopus assigned: 3 | Number of citations with DOI: 3
Article (Journal Article) | Scientific[3291826] [Validated]
All citations+mentions: 3, External citations: 2, Self citations: 1, Unhandled citations: 0
20.
Galambos, J ; Bielik, A ; Krasavin, M ; Orgován, Z ; Domány, G ; Nógrádi, K ; Wágner, G ; Balogh, GT ; Béni, Z ; Kóti, J et al.
Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications
JOURNAL OF MEDICINAL CHEMISTRY 60 : 6 pp. 2470-2484. , 15 p. (2017)
DOI WoS Scopus PubMed
Locked Publication:3291825 Admin approved Core Citing Journal Article (Article ) Scientific
Citing papers: 24 | Independent citation: 20 | Self citation: 4 | Unknown citation: 0 | Number of citations in WoS: 24 | Number of citations in Scopus: 17 | WoS/Scopus assigned: 24 | Number of citations with DOI: 24
Article (Journal Article) | Scientific[3291825] [Admin approved]
All citations+mentions: 24, External citations: 20, Self citations: 4, Unhandled citations: 0
2024-10-08 17:54