@article{MTMT:32544494,
	title = {The G protein database, GproteinDb},
	url = {https://m2.mtmt.hu/api/publication/32544494},
	author = {Pándy-Szekeres, Gáspár and Esguerra, Mauricio and Hauser, Alexander S and Caroli, Jimmy and Munk, Christian and Pilger, Steven and Keserű, György Miklós and Kooistra, Albert J and Gloriam, David E},
	doi = {10.1093/nar/gkab852},
	journal-iso = {NUCLEIC ACIDS RES},
	journal = {NUCLEIC ACIDS RESEARCH},
	volume = {50},
	unique-id = {32544494},
	issn = {0305-1048},
	year = {2022},
	eissn = {1362-4962},
	pages = {518-525},
	orcid-numbers = {Kooistra, Albert J/0000-0001-5514-6021; Gloriam, David E/0000-0002-4299-7561}
}

@article{MTMT:32044302,
	title = {Exploring protein hotspots by optimized fragment pharmacophores},
	url = {https://m2.mtmt.hu/api/publication/32044302},
	author = {Bajusz, Dávid and Wade, Warren S. and Satała, Grzegorz and Bojarski, Andrzej J. and Ilaš, Janez and Ebner, Jessica and Grebien, Florian and Papp, Henrietta and Jakab, Ferenc and Douangamath, Alice and Fearon, Daren and von Delft, Frank and Schuller, Marion and Ahel, Ivan and Wakefield, Amanda and Vajda, Sándor and Gerencsér, János and Pallai, Péter and Keserű, György Miklós},
	doi = {10.1038/s41467-021-23443-y},
	journal-iso = {NAT COMMUN},
	journal = {NATURE COMMUNICATIONS},
	volume = {12},
	unique-id = {32044302},
	issn = {2041-1723},
	year = {2021},
	eissn = {2041-1723},
	orcid-numbers = {Bajusz, Dávid/0000-0003-4277-9481; Ilaš, Janez/0000-0002-0124-0474; Grebien, Florian/0000-0003-4289-2281; Papp, Henrietta/0000-0003-3887-5657; Douangamath, Alice/0000-0002-9196-8644; Fearon, Daren/0000-0003-3529-7863; von Delft, Frank/0000-0003-0378-0017; Gerencsér, János/0000-0002-1928-0650}
}

@article{MTMT:31997728,
	title = {Controlling the selectivity of aminergic GPCR ligands from the extracellular vestibule},
	url = {https://m2.mtmt.hu/api/publication/31997728},
	author = {Egyed, Attila and Kelemen, Ádám Andor and Vass, Márton and Visegrády, András and Thee, Stephanie A. and Wang, Zhiyong and de Graaf, Chris and Brea, Jose and Loza, Maria Isabel and Leurs, Rob and Keserű, György Miklós},
	doi = {10.1016/j.bioorg.2021.104832},
	journal-iso = {BIOORG CHEM},
	journal = {BIOORGANIC CHEMISTRY},
	volume = {111},
	unique-id = {31997728},
	issn = {0045-2068},
	year = {2021},
	eissn = {1090-2120}
}

@article{MTMT:31817126,
	title = {GPCRdb in 2021: integrating GPCR sequence, structure and function},
	url = {https://m2.mtmt.hu/api/publication/31817126},
	author = {Kooistra, Albert J and Mordalski, Stefan and Pándy-Szekeres, Gáspár and Esguerra, Mauricio and Mamyrbekov, Alibek and Munk, Christian and Keserű, György Miklós and Gloriam, David E},
	doi = {10.1093/nar/gkaa1080},
	journal-iso = {NUCLEIC ACIDS RES},
	journal = {NUCLEIC ACIDS RESEARCH},
	volume = {49},
	unique-id = {31817126},
	issn = {0305-1048},
	year = {2021},
	eissn = {1362-4962},
	pages = {D335-D343},
	orcid-numbers = {Kooistra, Albert J/0000-0001-5514-6021; Gloriam, David E/0000-0002-4299-7561}
}

@article{MTMT:31698584,
	title = {Allosteric Molecular Switches in Metabotropic Glutamate Receptors},
	url = {https://m2.mtmt.hu/api/publication/31698584},
	author = {Orgován, Zoltán and Ferenczy, György and Keserű, György Miklós},
	doi = {10.1002/cmdc.202000444},
	journal-iso = {CHEMMEDCHEM},
	journal = {CHEMMEDCHEM},
	volume = {16},
	unique-id = {31698584},
	issn = {1860-7179},
	abstract = {Metabotropic glutamate receptors (mGlu) are class C G protein-coupled receptors of eight subtypes that are omnipresently expressed in the central nervous system. mGlus have relevance in several psychiatric and neurological disorders, therefore they raise considerable interest as drug targets. Allosteric modulators of mGlus offer advantages over orthosteric ligands owing to their increased potential to achieve subtype selectivity, and this has prompted discovery programs that have produced a large number of reported allosteric mGlu ligands. However, the optimization of allosteric ligands into drug candidates has proved to be challenging owing to induced-fit effects, flat or steep structure-activity relationships and unexpected changes in theirpharmacology. Subtle structural changes identified as molecular switches might modulate the functional activity of allosteric ligands. Here we review these switches discovered in the metabotropic glutamate receptor family..},
	keywords = {METABOTROPIC GLUTAMATE RECEPTORS; Allosteric modulation; MOLECULAR SWITCHES; GPCRs; water networks},
	year = {2021},
	eissn = {1860-7187},
	pages = {81-93},
	orcid-numbers = {Ferenczy, György/0000-0002-5771-4616}
}

@article{MTMT:32491765,
	title = {PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells},
	url = {https://m2.mtmt.hu/api/publication/32491765},
	author = {Prokop, Susanne Clara and Ábrányi-Balogh, Péter and Barti, Benjámin and Vámosi, Márton György and Zöldi, Miklós and Barna, László and Katona-Urbán, Gabriella and Tóth, András and Dudok, Barna and Egyed, Attila and Deng, Hui and Leggio, Gian Marco and Hunyady, László and van der Stelt, Mario and Keserű, György Miklós and Katona, István},
	doi = {10.1038/s41467-021-26757-z},
	journal-iso = {NAT COMMUN},
	journal = {NATURE COMMUNICATIONS},
	volume = {12},
	unique-id = {32491765},
	issn = {2041-1723},
	year = {2021},
	eissn = {2041-1723},
	orcid-numbers = {Prokop, Susanne Clara/0000-0003-0790-9324; Tóth, András/0000-0003-2746-9370; Dudok, Barna/0000-0001-5078-0090; Hunyady, László/0000-0002-8438-7251; van der Stelt, Mario/0000-0002-1029-5717}
}

@article{MTMT:31799297,
	title = {Controlling receptor function from the extracellular vestibule of G-protein coupled receptors},
	url = {https://m2.mtmt.hu/api/publication/31799297},
	author = {Egyed, Attila and Domány-Kovács, Katalin and Koványi, Bence and Horti, Ferenc and Kurko, Dalma and Kiss, Dóra Judit and Pándy-Szekeres, Gáspár and Greiner, István and Keserű, György Miklós},
	doi = {10.1039/D0CC05532H},
	journal-iso = {CHEM COMMUN},
	journal = {CHEMICAL COMMUNICATIONS},
	volume = {56},
	unique-id = {31799297},
	issn = {1359-7345},
	year = {2020},
	eissn = {1364-548X},
	pages = {14167-14170}
}

@article{MTMT:30834454,
	title = {Allosteric activation of metabotropic glutamate receptor 5},
	url = {https://m2.mtmt.hu/api/publication/30834454},
	author = {Jójárt, Balázs and Orgován, Zoltán and Márki, Árpád and Pándy-Szekeres, Gáspár and Ferenczy, György and Keserű, György Miklós},
	doi = {10.1080/07391102.2019.1638302},
	journal-iso = {J BIOMOL STRUCT DYN},
	journal = {JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS},
	volume = {38},
	unique-id = {30834454},
	issn = {0739-1102},
	year = {2020},
	eissn = {1538-0254},
	pages = {2624-2632},
	orcid-numbers = {Márki, Árpád/0000-0002-6056-8891; Ferenczy, György/0000-0002-5771-4616}
}

@article{MTMT:30763480,
	title = {Analysis of tractable allosteric sites in G protein-coupled receptors},
	url = {https://m2.mtmt.hu/api/publication/30763480},
	author = {Wakefield, Amanda E. and Mason, Jonathan S. and Vajda, Sandor and Keserű, György Miklós},
	doi = {10.1038/s41598-019-42618-8},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {9},
	unique-id = {30763480},
	issn = {2045-2322},
	year = {2019},
	eissn = {2045-2322}
}