TY  - JOUR
AU  - Vigvári, Szabolcs József
AU  - Sipos, Dávid
AU  - Solt, Jenő
AU  - Vincze, Áron
AU  - Kocsis, Béla
AU  - Nemes, Zsuzsanna
AU  - Kappéter, Ágnes
AU  - Feiszt, Zsófia
AU  - Kovács, Beáta
AU  - Péterfi, Zoltán
TI  - Faecal microbiota transplantation for Clostridium difficile infection using a lyophilized inoculum from non-related donors: A case series involving 19 patients
JF  - ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA
J2  - ACTA MICROBIOL IMMUNOL HUNG
VL  - 66
PY  - 2019
IS  - 1
SP  - 69
EP  - 78
PG  - 10
SN  - 1217-8950
DO  - 10.1556/030.64.2017.042
UR  - https://m2.mtmt.hu/api/publication/3304835
ID  - 3304835
N1  - Department of Infectious Diseases, 1st Department of Internal Medicine, University of Pécs, Pécs, Hungary            
            Department of Gastroenterology, 1st Department of Internal Medicine, University of Pécs, Pécs, Hungary            
            Department of Medical Microbiology and Immunology, University of Pécs, Pécs, Hungary            
            Cited By :10            
            Export Date: 23 April 2024            
            Correspondence Address: Vigvári, S.; Department of Infectious Diseases, Hungary; email: szabolcs.vigvari@gmail.com
AB  - Faecal microbiota transplantation (FMT) has been reported to be effective in treating relapsing of refractory Clostridium difficile infections, although some practical barriers are limiting its widespread use. In this study, our objective was to evaluate the rate of resolution of diarrhea following administration of lyophilized and resolved FMT via a nasogastric (NG) tube. We recruited 19 patients suffered from laboratory-confirmed C. difficile infection. Each of them was treated by lyophilized and resolved inoculum through a NG tube. One participant succumbed following the procedure due to unrelated diseases. Out of 18 cases, 15 patients reportedly experienced a resolution of the symptoms. One patient was treated with another course of antibiotics, and two of the non-responders were successfully retreated with another course of FMT utilizing a lyophilized inoculum. Notably, no significant adverse activities were observed. In accordance to our clinical experiences, a patient will likely benefit from FMT treatment including lyophilized inoculum.
LA  - English
DB  - MTMT
ER  -