TY  - JOUR
AU  - Erős, Adrienn
AU  - Soós, Alexandra
AU  - Hegyi, Péter
AU  - Szakács, Zsolt
AU  - Benke, Márton
AU  - Szűcs, Ákos
AU  - Hartmann, Petra
AU  - Erőss, Bálint Mihály
AU  - Sarlós, Patrícia
TI  - Sarcopenia as an independent predictor of the surgical outcomes of patients with inflammatory bowel disease: a meta-analysis
JF  - SURGERY TODAY
J2  - SURG TODAY
VL  - 50
PY  - 2020
IS  - 10
SP  - 1138
EP  - 1150
PG  - 13
SN  - 0941-1291
DO  - 10.1007/s00595-019-01893-8
UR  - https://m2.mtmt.hu/api/publication/30850194
ID  - 30850194
AB  - Patients with inflammatory bowel disease (IBD) are at risk of sarcopenia, which is associated with poor clinical outcomes. We conducted this study to assess whether sarcopenia predicts the need for surgery and postoperative complications in patients with IBD. We performed a systematic search of four electronic databases, last updated in March, 2019. Data from studies comparing rates of surgery and postoperative complications in sarcopenic IBD patients versus non-sarcopenic IBD patients were pooled with the random-effects models. We calculated the odds ratios (OR) with a 95% confidence interval (CI). Ten studies with a collective total of 885 IBD patients were included in our meta-analysis. Although the analysis of raw data did not reveal significant differences between the two groups with respect to the rate of surgery and postoperative complications (OR = 1.826; 95% CI 0.913-3.654; p = 0.089 and OR = 3.265; 95% CI 0.575-18.557; p = 0.182, respectively), the analysis of adjusted data identified sarcopenia as an independent predictor for both of the undesirable outcomes (OR = 2.655; 95% CI 1.121-6.336; p = 0.027 and OR = 6.097; 95% CI 1.756-21.175; p = 0.004, respectively). Thus, early detection of sarcopenia in patients with IBD is important to prevent undesirable outcomes.
LA  - English
DB  - MTMT
ER  -