TY  - JOUR
AU  - Szanya, J
AU  - Szakály, Péter
AU  - Magyarlaki, Tamás
AU  - Balogh, Z
AU  - Nagy, Judit
AU  - Nagy, KK
TI  - Predictive morphological findings in "zero-hour" biopsies of renal allografts.
JF  - ACTA CHIRURGICA HUNGARICA
J2  - ACTA CHIR HUNG
VL  - 36
PY  - 1997
IS  - 1-4
SP  - 346
EP  - 348
PG  - 3
SN  - 0231-4614
UR  - https://m2.mtmt.hu/api/publication/1434364
ID  - 1434364
N1  - Export Date: 27 January 2024
AB  - "Zero-hour" biopsies of 65 donors have been performed since 1994. Donor kidneys were categorized into five groups based on the morphological findings in "zero-hour" biopsies. No morphological abnormalities were found in 38% of the cases (group 1). Arteriosclerosis was present in 31% of donor kidneys (group 2). Specific morphological alterations, i.e. acute tubular necrosis [21.5%], tubulointerstitial nephritis [6.2%] or glomerulonephritis [3.1%] were detectable in the cases remained (group 3-5). During an average of 336 posttransplant days clinical and histological follow up was performed (50 rebiopsies). Statistical data of mismatch (1.4-2.0), average of donor/recipient age (35-42 years), cold and warm ischaemic time (1290 and 66 min) were comparable in all groups. According to our observations: 1. higher creatinin was found in grafts with arteriosclerosis (group 2) (p < 0.05), 2. there were more non-viable grafts and longer period of delayed graft function in acute tubular necrosis (group 3), 3 higher creatinin, rejections with the need of rehemodialysis were observed in four cases of tubulointerstitial nephritis (TIN-group 4). Glomerulonephritis (GN-group 5) grafts had only delayed graft function, however these groups were few for statistical evaluation. Biopsy complication in 1/115 cases was found (rebiopsy induced kidney haemorrhage). In conclusion, "zero-hour" biopsies can be useful and safe tools to predict early graft function. Besides "zero-hour" biopsies help the histological interpretation of consecutive graft rebiopsies.
LA  - English
DB  - MTMT
ER  -