TY  - JOUR
AU  - Schuster, Ildikó
AU  - Koch, A
AU  - Heydenreich, M
AU  - Kleinpeter, E
AU  - Lázár, László
AU  - Fülöp, Ferenc
TI  - Synthesis and conformational analysis of phenyl-substituted 1,3,2-oxazaphosphino[4,3-a]- and 1,2,3-oxathiazino[4,3-a]isoquinolines
JF  - JOURNAL OF MOLECULAR STRUCTURE
J2  - J MOL STRUCT
VL  - 888
PY  - 2008
IS  - 1-3
SP  - 124
EP  - 137
PG  - 14
SN  - 0022-2860
DO  - 10.1016/j.molstruc.2007.11.054
UR  - https://m2.mtmt.hu/api/publication/1140193
ID  - 1140193
N1  - Funding Agency and Grant Number: Hungarian Scientific Research Foundation [OTKA T 049407]
            Funding text: I.S. is grateful to the German Academic Exchange Service (DAAD) for a grant. The authors thank the Hungarian Scientific Research Foundation (Grant No. OTKA T 049407) for financial support.
AB  - Through the ring closures of tetrahydroisoquinoline 1,3-amino alcohols
bearing a phenyl group in the side-chain, diastereomers of novel 1- or
2-phenyl-substituted 1,3,2-oxazaphosphino[4,3-a]isoquinoline 4-oxides,
and 1,2,3-oxathiazino[4,3-a]isoquinoline 4-oxides and 4,4-dioxides were
prepared. NMR analysis and DFT calculations on the prepared
tetrahydroisoquinoline-condensed 1,2,3-heterocycles revealed that their
conformational equilibria of cis(1)-trans-cis(2) type are influenced by
the relative configuration of P-4 in the 1,3,2-oxazaphosphinanes, and
by the position of the phenyl group in the 1,2,3-oxathiazines. (C) 2007
Elsevier B.V. All rights reserved.
LA  - English
DB  - MTMT
ER  -