@article{MTMT:1124327,
	title = {Synthesis and conformational analysis of tetrahydroisoquinoline-fused 1,3,2-oxazaphospholidines and 1,2,3-oxathiazolidines},
	url = {https://m2.mtmt.hu/api/publication/1124327},
	author = {Schuster, Ildikó and Koch, A and Heydenreich, M and Kleinpeter, E and Forró, Enikő and Lázár, László and Sillanpaa, R and Fülöp, Ferenc},
	doi = {10.1002/ejoc.200701026},
	journal-iso = {EUR J ORG CHEM},
	journal = {EUROPEAN JOURNAL OF ORGANIC CHEMISTRY},
	volume = {2008},
	unique-id = {1124327},
	issn = {1434-193X},
	abstract = {The cyclizations of tetrahydroisoquinoline 1,2-amino alcohols with
		phenylphosphonic dichloride, bis(2-chloroethyl)phosphoramidic
		dichloride, thionyl chloride and sulfuryl chloride were utilized to
		synthesize
		1,5,6,10b-tetrahydro-1,3,2-oxazaphospholo[4,3-a]isoquinolines (2, 3),
		1,5,10,10a-tetrahydro-1,3,2-oxazaphospholo[3,4-b]isoquinolines (8, 9),
		1,5,6,10b-tetrahydro-1,2,3-oxathiazolo[4,3-a]isoquinolines (4-6) and a
		1,5,10,10a-tetrahydro-1,2,3-oxathiazolo[3,4-b]isoquinoline (11), which
		are the first representatives of these ring systems. NMR spectroscopic
		analysis revealed the existence of conformational equilibria that are
		fast on the NMR timescale. Theoretical DFT calculations pointed to the
		participation of generally two preferred conformers in the
		conformational equilibria; the positions of the equilibria were
		indicated by the experimental NMR spectroscopic parameters, and they
		are in good agreement with the theoretically calculated energy
		differences of the participating conformers. For two compounds, which
		could be not isolated (10, 12), both the preferred conformers and the
		stereochemistry could be concluded from the DFT calculation results.
		((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).},
	year = {2008},
	eissn = {1099-0690},
	pages = {1464-1472},
	orcid-numbers = {Forró, Enikő/0000-0001-6796-3889; Lázár, László/0000-0002-2135-8496; Fülöp, Ferenc/0000-0003-1066-5287}
}