@article{MTMT:32907495, title = {Influence of Aliphatic Chain Length on Structural, Thermal and Electrochemical Properties of n-alkylene Benzyl Alcohols : A Study of the Odd-Even Effect}, url = {https://m2.mtmt.hu/api/publication/32907495}, author = {Balić, Tomislav and Paurević, Marija and Počkaj, Marta and Medvidović-Kosanović, Martina and Goman, Dominik and Széchenyi, Aleksandar and Preisz, Zsolt and Kunsági-Máté, Sándor}, doi = {10.3390/molecules27123781}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {27}, unique-id = {32907495}, issn = {1420-3049}, abstract = {The century-old, well-known odd-even effect phenomenon is still a very attractive and intriguing topic in supramolecular and nano-scale organic chemistry. As a part of our continuous efforts in the study of supramolecular chemistry, we have prepared three novel aromatic alcohols (1,2-bis[2-(hydroxymethyl)phenoxy]butylene (Do4OH), 1,2-bis[2-(hydroxymethyl)phenoxy]pentylene (Do5OH) and 1,2-bis[2-(hydroxymethyl)phenoxy]hexylene (Do6OH)) and determined their crystal and molecular structures by single-crystal X-ray diffraction. In all compounds, two benzyl alcohol groups are linked by an aliphatic chain of different lengths (CH2)n; n = 4, 5 and 6. The major differences in the molecular structures were found in the overall planarity of the molecules and the conformation of the aliphatic chain. Molecules with an even number of CH2 groups tend to be planar with an all-trans conformation of the aliphatic chain, while the odd-numbered molecule is non-planar, with partial gauche conformation. A direct consequence of these structural differences is visible in the melting points-odd-numbered compounds of a particular series display systematically lower melting points. Crystal and molecular structures were additionally studied by the theoretical calculations and the melting points were correlated with packing density and the number of CH2 groups. The results have shown that the generally accepted rule, higher density = higher stability = higher melting point, could not be applied to these compounds. It was found that the denser packaging causes an increase in the percentage of repulsive H‧‧‧H interactions, thereby reducing the stability of the crystal, and consequently, the melting points. Another interesting consequence of different molecular structures is their electrochemical and antioxidative properties-a non-planar structure displays the highest oxidation peak of hydroxyl groups and moderate antioxidant activity.}, keywords = {crystal structures; odd-even effect; Aromatic alcohols; aliphatic chain; melting point deviation}, year = {2022}, eissn = {1420-3049}, orcid-numbers = {Széchenyi, Aleksandar/0000-0001-9207-2551} } @article{MTMT:33090440, title = {Szemelvények a PTE GyTK Szerves és Gyógyszerkémiai Intézetének újabb (2013-2021) kutatási eredményeiből}, url = {https://m2.mtmt.hu/api/publication/33090440}, author = {Bognár, Balázs and Lemli, Beáta and Kőrösi, László Tamás and Mohamed Ameen, Hiba Farooq and Derdák, Diána and Isbera, Mostafa and Preisz, Zsolt and Úr, Györgyi and Pápayné Sár, Cecília and Kunsági-Máté, Sándor and Kálai, Tamás}, doi = {10.24100/MKF.2022.02.68}, journal-iso = {MAGY KÉM FOLY KÉM KÖZL}, journal = {MAGYAR KÉMIAI FOLYÓIRAT - KÉMIAI KÖZLEMÉNYEK (1997-)}, volume = {128}, unique-id = {33090440}, issn = {1418-9933}, year = {2022}, eissn = {1418-8600}, pages = {68-78}, orcid-numbers = {Lemli, Beáta/0000-0001-8903-1337} } @book{MTMT:32646528, title = {X. JUBILEUMI INTERDISZCIPLINÁRIS DOKTORANDUSZ KONFERENCIA 2021 TANULMÁNYKÖTET = 10th JUBILEE INTERDISCIPLINARY DOCTORAL CONFERENCE 2021 CONFERENCE BOOK}, url = {https://m2.mtmt.hu/api/publication/32646528}, isbn = {9789634298199}, editor = {Kajos, Luca Fanni and Bali, Cintia and Preisz, Zsolt and Szabó, Rebeka}, publisher = {Doctoral Student Association of the University of Pécs}, unique-id = {32646528}, year = {2022}, orcid-numbers = {Kajos, Luca Fanni/0000-0002-0574-5787} } @mastersthesis{MTMT:33685148, title = {A metotrexát és egyes analogonjainak másodlagos kölcsönhatásai és antioxidáns tulajdonságai}, url = {https://m2.mtmt.hu/api/publication/33685148}, author = {Preisz, Zsolt}, unique-id = {33685148}, year = {2022} } @book{MTMT:32526207, title = {10th Jubilee Interdisciplinary Doctoral Conference : Book of Abstracts = 10. Jubileumi Interdiszciplináris Doktorandusz Konferencia : Absztraktkötet}, url = {https://m2.mtmt.hu/api/publication/32526207}, isbn = {9789634298205}, editor = {Kajos, Luca Fanni and Bali, Cintia and Preisz, Zsolt and Polgár, Petra Ibolya and Glázer-Kniesz, Adrienn and Tislér, Ádám and Szabó, Rebeka}, publisher = {Doctoral Student Association of the University of Pécs}, unique-id = {32526207}, year = {2021}, orcid-numbers = {Kajos, Luca Fanni/0000-0002-0574-5787; Polgár, Petra Ibolya/0000-0003-2710-6326} } @article{MTMT:31604212, title = {Effect of methotrexate and its photodegradation products on the temperature induced denaturation of human serum albumin}, url = {https://m2.mtmt.hu/api/publication/31604212}, author = {Preisz, Zsolt and Kunsági-Máté, Sándor}, doi = {10.1016/j.saa.2020.118905}, journal-iso = {SPECTROCHIM ACTA A}, journal = {SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY}, volume = {245}, unique-id = {31604212}, issn = {1386-1425}, year = {2021}, eissn = {1873-3557} } @article{MTMT:32396707, title = {Weak Interactions of the Isomers of Phototrexate and Two Cavitand Derivatives}, url = {https://m2.mtmt.hu/api/publication/32396707}, author = {Preisz, Zsolt and Nagymihaly, Zoltan and Kollár, László and Kálai, Tamás and Kunsági-Máté, Sándor}, doi = {10.3390/ijms221910764}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {22}, unique-id = {32396707}, issn = {1661-6596}, abstract = {The interactions of two conformers of newly synthesized photoswitchable azobenzene analogue of methotrexate, called Phototrexate, with two cavitand derivatives, have been investigated in dimethyl sulfoxide medium. Photoluminescence methods have been applied to determine the complex stabilities and the related enthalpy and entropy changes associated to the complex formation around room temperature. Results show opposite temperature dependence of complex stabilities. The structure of the upper rims of the host molecules and the reordered solvent structure were identified as the background of the opposite tendencies of temperature dependence at molecular level. These results can support the therapeutic application of the photoswitchable phototrexate, because the formation of inclusion complexes is a promising method to regulate the pharmacokinetics of drug molecules.}, keywords = {CHEMOTHERAPY; FLUORESCENCE; THERMODYNAMICS; inclusion complex; Cavitand; Phototrexate}, year = {2021}, eissn = {1422-0067} } @{MTMT:32217277, title = {A metotrexát és fotodegradációs termékeinek hatása a humán szérum albumin hődenaturációjára}, url = {https://m2.mtmt.hu/api/publication/32217277}, author = {Preisz, Zsolt}, booktitle = {XXIV. Tavaszi Szél Konferencia 2021: Absztrakt kötet}, unique-id = {32217277}, year = {2021}, pages = {496-496} } @article{MTMT:32102470, title = {Comparative EPR Study on the Scavenging Effect of Methotrexate with the Isomers of Its Photoswitchable Derivative}, url = {https://m2.mtmt.hu/api/publication/32102470}, author = {Preisz, Zsolt and Hartvig, Nóra and Bognár, Balázs and Kálai, Tamás and Kunsági-Máté, Sándor}, doi = {10.3390/ph14070665}, journal-iso = {PHARMACEUTICALS-BASE}, journal = {PHARMACEUTICALS}, volume = {14}, unique-id = {32102470}, year = {2021}, eissn = {1424-8247} } @article{MTMT:32634855, title = {Some Interactions of the Novel Photoswitchable Compound Phototrexate}, url = {https://m2.mtmt.hu/api/publication/32634855}, author = {Preisz, Zsolt and Bognár, Balázs and Kálai, Tamás and Kollár, László and Kunsági-Máté, Sándor}, doi = {10.33892/aph.2021.91.300-301}, journal-iso = {ACTA PHARM HUNG}, journal = {ACTA PHARMACEUTICA HUNGARICA}, volume = {91}, unique-id = {32634855}, issn = {0001-6659}, year = {2021}, eissn = {1587-1495}, pages = {300-301} }