https://m2.mtmt.hu/
eng
2024-03-29 10:23
true
true
1
16
16
20
100
1
16
DESC
publishedYear
false
ASC
firstAuthor
true
JournalArticle
34232792
VALIDATED
true
0
false
2024-02-23T12:07:20.214+0000
2024-01-29T08:05:29.694+0000
2023-11-02T14:03:25.211+0000
true
10015499
Csanády
László
/api/author/10015499
Author
true
10015499
2024-02-17T07:04:09.323+0000
2024-01-29T08:05:30.017+0000
true
10080205
Szalóky-Siki
Ágnes
/api/admin/10080205
Admin
true
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Simon, Márton A
Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein.
true
true
/api/journal/10031024
REVIEWED
true
false
10031024
false
10031024
true
2050-084X
2050-084X
Journal
FOREIGN
12
e90736
e90736
19
2023
CFTR, the anion channel mutated in cystic fibrosis patients, is a model ABC protein whose ATP-driven conformational cycle is observable at single-molecule level in patch-clamp recordings. Bursts of CFTR pore openings are coupled to tight dimerization of its two nucleotide-binding domains (NBDs) and in wild-type (WT) channels are mostly terminated by ATP hydrolysis. The slow rate of non-hydrolytic closure - which determines how tightly bursts and ATP hydrolysis are coupled - is unknown, as burst durations of catalytic site mutants span a range of ~200-fold. Here, we show that Walker A mutation K1250A, Walker B mutation D1370N, and catalytic glutamate mutations E1371S and E1371Q all completely disrupt ATP hydrolysis. True non-hydrolytic closing rate of WT CFTR approximates that of K1250A and E1371S. That rate is slowed ~15-fold in E1371Q by a non-native inter-NBD H-bond, and accelerated ~15-fold in D1370N. These findings uncover unique features of the NBD interface in human CFTR.
Funding
2036410
/api/funding/2036410
false
true
Funding
2036411
/api/funding/2036411
false
true
Funding
2036412
/api/funding/2036412
false
true
true
2023
true
true
true
false
true
false
GOLD
2024-02-23
false
http://elife.elifesciences.org/
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
D1
false
10015499,10020191
false
false
false
2023-11-06T12:07:55.231+0000
Biokémiai Tanszék (SE / AOK / I / BMBI); Biokémiai és Molekuláris Biológiai Intézet (SE / AOK / I); HCEMM-SE Molekuláris Csatornabetegségek Kutatóc... (SE / AOK / I / BMBI / BT); HUN-REN-SE Ioncsatorna Kutatócsoport (SE / AOK / I / BMBI / BT)
4
18
4
4
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
111064555
/api/authorship/111064555
1
0.25
true
false
false
Author
10066737
/api/author/10066737
Simon
Márton
true
true
Simon
Márton A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111064556
/api/authorship/111064556
2
0.25
false
false
false
Author
10052053
/api/author/10052053
Iordanov
Iordan
true
10052053
true
Iordanov
Iordan
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111064557
/api/authorship/111064557
3
0.25
false
false
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
Andras
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111064558
/api/authorship/111064558
4
0.25
false
true
true
Author
10015499
/api/author/10015499
Csanády
László
true
10015499
true
Csanády
László
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
24612551
/api/publicationidentifier/24612551
IDENTICAL
10.7554/eLife.90736
https://doi.org/10.7554/eLife.90736
false
true
PublicationIdentifier
25378278
/api/publicationidentifier/25378278
IDENTICAL
001134823500001
https://www.webofscience.com/wos/woscc/full-record/001134823500001
true
true
PublicationIdentifier
24612552
/api/publicationidentifier/24612552
IDENTICAL
85174752039
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85174752039
false
true
PublicationIdentifier
24612550
/api/publicationidentifier/24612550
IDENTICAL
37782012
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37782012&dopt=Abstract
false
true
Keyword
1519
/api/keyword/1519
true
1519
true
Keyword
7673
/api/keyword/7673
true
7673
true
Keyword
1066395
/api/keyword/1066395
true
1066395
true
Keyword
1175577
/api/keyword/1175577
true
1175577
true
Keyword
1264463
/api/keyword/1264463
true
1264463
true
Keyword
3168070
/api/keyword/3168070
true
true
Keyword
3168071
/api/keyword/3168071
true
true
Keyword
3168072
/api/keyword/3168072
true
true
SjrRating
11358162
/api/sjrrating/11358162
14
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1301
/api/classificationexternal/1301
true
1301
true
D1
FROM_LAST_YEAR
true
true
/api/publication/34232792
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10066737"> <a href="/gui2/?type=authors&mode=browse&sel=10066737" target="_blank">Simon, Márton A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10052053"> <a href="/gui2/?type=authors&mode=browse&sel=10052053" target="_blank">Iordanov, Iordan</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, Andras</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10015499"> <a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády, László ✉</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34232792" mtid="34232792" target="_blank">Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein.</a></div> <div class="pub-info"> <span class="journal-title">ELIFE</span> <span class="journal-volume">12</span> <span class="page"> Paper: e90736 , 19 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.7554/eLife.90736" target="_blank" href="https://doi.org/10.7554/eLife.90736"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001134823500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001134823500001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85174752039" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85174752039"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37782012" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37782012&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:34232792 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10066737"><a href="/gui2/?type=authors&mode=browse&sel=10066737" target="_blank">Simon Márton A (<span class="authorship-author-name">Simon Márton</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Biokémiai és Molekuláris Biológiai Intézet; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Biokémiai Tanszék; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/HCEMM-SU Molecular Channelopathies Research Group</span> ; <span class="author-name" mtid="10052053"><a href="/gui2/?type=authors&mode=browse&sel=10052053" target="_blank">Iordanov Iordan (<span class="authorship-author-name">Iordanov Iordan</span> <span class="authorAux-mtmt"> biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Biokémiai és Molekuláris Biológiai Intézet; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Biokémiai Tanszék; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/HUN-REN-SE Ion Channel Research Group; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/HCEMM-SU Molecular Channelopathies Research Group</span> ; <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi Andras (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Biokémiai és Molekuláris Biológiai Intézet; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Biokémiai Tanszék; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/HUN-REN-SE Ion Channel Research Group; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/HCEMM-SU Molecular Channelopathies Research Group</span> ; <span class="author-name" mtid="10015499"><a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády László ✉ (<span class="authorship-author-name">Csanády László</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Biokémiai és Molekuláris Biológiai Intézet; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Biokémiai Tanszék; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/HUN-REN-SE Ion Channel Research Group; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/HCEMM-SU Molecular Channelopathies Research Group</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;34232792" target="_blank">Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein.</a></div> <div> <span class="journal-title">ELIFE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2050-084X">2050-084X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2050-084X">2050-084X</a>)</span>: <span class="journal-volume">12</span> <span class="page"> Paper e90736. 19 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.7554/eLife.90736" target="_blank" href="https://doi.org/10.7554/eLife.90736"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001134823500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001134823500001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85174752039" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85174752039"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37782012" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37782012&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34232792&sort=publishedYear,desc&sort=title"> Number of cited publications: 12 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 34232792</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (KKP 144199), (UNKP-22-3-II-SE-12), (CSANAD21G0) </div> <div class="notDuplums"><a target="_blank" href="/api/publication/34232792/notduplums">2 marked as not duplum</a> </div> <div class="lastModified">Last Modified: 2024.01.29. 09:05 Ágnes Szalóky-Siki (SE_KK_Admin5_SZSA, admin) </div> </div></div>
JournalArticle
34064647
VALIDATED
true
Department of Biochemistry, Semmelweis University, Tuzolto u. 37-47, Budapest, 1094, Hungary
Department of Physiology, Semmelweis University, Tuzolto u. 37-47, Budapest, 1094, Hungary
ELKH-SE Ion Channel Research Group, Semmelweis University, Tuzolto u. 37-47, Budapest, 1094, Hungary
HCEMM-SE Molecular Channelopathies Research Group, Semmelweis University, Tuzolto u. 37-47, Budapest, 1094, Hungary
Export Date: 4 September 2023
Correspondence Address: Szollosi, A.; Department of Biochemistry, Tuzolto u. 37-47, Hungary; email: szollo5@gmail.com
Chemicals/CAS: adenosine diphosphate ribose, 20762-30-5; calcium, 7440-70-2, 14092-94-5; Adenosine Diphosphate Ribose; Calcium; Cations; Lipid Bilayers; TRPM Cation Channels
Funding details: 739593
Funding details: Nemzeti Kutatási, Fejlesztési és Innovaciós Alap, NKFIA, KKP 144199
Funding text 1: This work was supported by Semmelweis Science and Innovation Fund STIA_18_M; EU Horizon 2020 Research and Innovation Program grant 739593 and National Research, Development and Innovation Fund grant KKP 144199. We thank László Csanády for funding and thorough reading and comments on the manuscript. We thank Balázs Tóth for help with poly- l -lysine measurements and stimulating discussions.
0
false
2024-02-22T21:45:29.266+0000
2023-11-30T07:57:51.106+0000
2023-07-17T08:44:31.802+0000
true
10020191
Szöllősi
András
/api/author/10020191
Author
true
10020191
2024-03-02T20:56:42.752+0000
2024-03-02T20:56:42.752+0000
2023-07-25T10:08:33.682+0000
true
10062250
Molnár-Taga
Márta
/api/admin/10062250
Admin
true
10062250
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Szollosi, Andras
Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer
true
true
/api/journal/10019966
REVIEWED
true
false
10019966
false
10019966
true
2045-2322
2045-2322
Journal
FOREIGN
13
1
11471
11471
10
2023
Transient receptor potential melastatin 2 (TRPM2) cation channel activity is required for insulin secretion, immune cell activation and body heat control. Channel activation upon oxidative stress is involved in the pathology of stroke and neurodegenerative disorders. Cytosolic Ca 2+ , ADP-ribose (ADPR) and phosphatidylinositol-4,5-bisphosphate (PIP 2 ) are the obligate activators of the channel. Several TRPM2 cryo-EM structures have been resolved to date, yet functionality of the purified protein has not been tested. Here we reconstituted overexpressed and purified TRPM2 from Nematostella vectensis (nvTRPM2) into lipid bilayers and found that the protein is fully functional. Consistent with the observations in native membranes, nvTRPM2 in lipid bilayers is co-activated by cytosolic Ca 2+ and either ADPR or ADPR-2′-phosphate (ADPRP). The physiological metabolite ADPRP has a higher apparent affinity than ADPR. In lipid bilayers nvTRPM2 displays a large linear unitary conductance, its open probability (P o ) shows little voltage dependence and is stable over several minutes. P o is high without addition of exogenous PIP 2 , but is largely blunted by treatment with poly- l -Lysine, a polycation that masks PIP 2 headgroups. These results indicate that PIP 2 or some other activating phosphoinositol lipid co-purifies with nvTRPM2, suggesting a high PIP 2 binding affinity of nvTRPM2 under physiological conditions.
Funding
2029213
/api/funding/2029213
false
true
Funding
2029214
/api/funding/2029214
false
true
Funding
2029215
/api/funding/2029215
false
true
true
true
2023
true
true
true
false
true
false
GOLD
2024-02-22
false
http://www.nature.com/srep/index.html
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
D1
A nemzetközi
false
10020191
false
false
false
2023-07-17T14:00:42.495+0000
Biokémiai Tanszék (SE / AOK / I / BMBI); Biokémiai és Molekuláris Biológiai Intézet (SE / AOK / I); ELKH-SE Ioncsatorna Kutatócsoport (SE / AOK / I / BMBI / BT); HCEMM-SE Molekuláris Csatornabetegségek Kutatóc... (SE / AOK / I / BMBI / BT); MTA-SE Lendület Ioncsatorna Kutatócsoport (SE / AOK / I / BMBI / BT); Élettani Intézet (SE / AOK / I)
2
18
6
2
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
109293544
/api/authorship/109293544
1
0.5
true
false
true
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
Andras
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
109293545
/api/authorship/109293545
2
0.5
false
true
false
Author
10034375
/api/author/10034375
Almássy
János
true
10034375
true
Almássy
János
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
24169490
/api/publicationidentifier/24169490
IDENTICAL
10.1038/s41598-023-38640-6
https://doi.org/10.1038/s41598-023-38640-6
false
true
PublicationIdentifier
24400372
/api/publicationidentifier/24400372
IDENTICAL
001055239000013
https://www.webofscience.com/wos/woscc/full-record/001055239000013
true
true
PublicationIdentifier
24169491
/api/publicationidentifier/24169491
IDENTICAL
85164760224
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85164760224
false
true
PublicationIdentifier
24177897
/api/publicationidentifier/24177897
IDENTICAL
37454209
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37454209&dopt=Abstract
true
true
MtaRating
519359
/api/mtarating/519359
RatingType
10007
/api/ratingtype/10007
SZTB
Institute
14102
/api/institute/14102
0
false
true
Szociológiai Tudományos Bizottság
Szociológiai Tudományos Bizottság
true
14102
true
true
true
A nemzetközi
true
19359
true
MtaRating
11551161
/api/mtarating/11551161
RatingType
10010
/api/ratingtype/10010
RegTB
Institute
14100
/api/institute/14100
0
false
true
Regionális Tudományok Bizottsága
Regionális Tudományok Bizottsága
true
14100
true
true
true
B nemzetközi
false
true
SjrRating
11400901
/api/sjrrating/11400901
13
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1000
/api/classificationexternal/1000
true
1000
true
D1
FROM_LAST_YEAR
true
true
/api/publication/34064647
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, Andras ✉</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10034375"> <a href="/gui2/?type=authors&mode=browse&sel=10034375" target="_blank">Almássy, János</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34064647" mtid="34064647" target="_blank">Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer</a></div> <div class="pub-info"> <span class="journal-title">SCIENTIFIC REPORTS</span> <span class="journal-volume">13</span> : <span class="journal-issue">1</span> <span class="page"> Paper: 11471 , 10 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1038/s41598-023-38640-6" target="_blank" href="https://doi.org/10.1038/s41598-023-38640-6"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001055239000013" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001055239000013"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85164760224" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85164760224"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37454209" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37454209&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:34064647 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" mtid="10020191"><a
href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi Andras ✉
(<span class="authorship-author-name">Szöllősi András</span>
<span class="authorAux-mtmt"> Biokémia</span>)
</a>
</span>
<span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/MTA-SE Ion Channel Research Group; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Biokémiai és Molekuláris Biológiai Intézet; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Biokémiai Tanszék; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/ELKH-SE Ion Channel Research Group; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/HCEMM-SU Molecular Channelopathies Research Group</span>
;
<span class="author-name" mtid="10034375"><a
href="/gui2/?type=authors&mode=browse&sel=10034375" target="_blank">Almássy János
(<span class="authorship-author-name">Almássy János</span>
<span class="authorAux-mtmt"> sejtélettan, incsatornák élettana, intracellulá...</span>)
</a>
</span>
<span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Physiology</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34064647" target="_blank">Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer</a></div> <div> <span class="journal-title">SCIENTIFIC REPORTS</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2045-2322">2045-2322</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2045-2322">2045-2322</a>)</span>:
<span class="journal-volume">13</span> <span class="journal-issue">1</span>
<span class="page">
Paper 11471.
10 p.
</span> <span class="year">(2023)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Language:
English
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="10.1038/s41598-023-38640-6" target="_blank" href="https://doi.org/10.1038/s41598-023-38640-6">
DOI
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="001055239000013" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001055239000013">
WoS
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="85164760224" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85164760224">
Scopus
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="37454209" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37454209&dopt=Abstract">
PubMed
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34064647&sort=publishedYear,desc&sort=title">
Number of cited publications: 8
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Publication: 34064647</span>
| <span class="status-data status-VALIDATED"> Validated
</span>
Core Citing
| <span class="type-subtype">Journal Article
( Article
)
</span>
| <span class="pub-category">Scientific</span>
| <span class="publication-sourceOfData">kézi felvitel</span>
</div>
<div class="funder"> (STIA_18_M), Establishing the Hungarian Center of Excellence for Molecular Medicine in partnership with EMBL(739593) Funder: Horizon 2020, (KKP 144199) </div>
<div class="lastModified">Last Modified: 2023.11.30. 08:57 Márta Molnár-Taga (SE 4-es admin)
</div>
<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Department of Biochemistry, Semmelweis University, Tuzolto u. 37-47, Budapest, 1094, Hungary
Department of Physiology, Semmelweis University, Tuzolto u. 37-47, Budapest, 1094, Hungary
ELKH-SE Ion Channel Research Group, Semmelweis University, Tuzolto u. 37-47, Budapest, 1094, Hungary
HCEMM-SE Molecular Channelopathies Resea...</pre>
</div></div>
JournalArticle
32040119
VALIDATED
true
Department of Medical Biochemistry, Semmelweis University, Budapest, 1085, Hungary
MTA-SE Lendület Ion Channel Research Group, Semmelweis University, Budapest, 1085, Hungary
HCEMM-SE Molecular Channelopathies Research Group, Semmelweis University, Budapest, 1085, Hungary
Cited By :2
Export Date: 9 March 2022
Correspondence Address: Szollosi, A.; Department of Medical Biochemistry, Hungary; email: szollosi.andras@med.semmelweis-univ.hu
Funding details: 739593
Funding details: LP2017-14/2017
Funding text 1: Supported by MTA Lend?let grant LP2017-14/2017 and EU Horizon 2020 Research and Innovation Program grant 739593.
Funding text 2: Funding: Supported by MTA Lendület grant LP2017-14/2017 and EU Horizon 2020 Research and Innovation Program grant 739593.
0
false
2024-02-21T10:50:27.760+0000
2023-11-29T14:38:49.889+0000
2021-05-28T11:27:32.560+0000
true
10074913
Sághi-Keszthelyi
Anna
/api/admin/10074913
Admin
true
2023-02-24T10:10:13.808+0000
2022-02-24T10:11:51.354+0000
true
10062250
Molnár-Taga
Márta
/api/admin/10062250
Admin
true
10062250
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
1134514
Survey paper
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/1134514
Összefoglaló cikk
SubType
102
true
1134514
true
1
/api/category/1
Category
true
1
Szollosi, A.
Two decades of evolution of our understanding of the transient receptor potential melastatin 2 (Trpm2) cation channel
true
true
/api/journal/10024487
REVIEWED
true
false
10024487
false
10024487
true
2075-1729
Journal
FOREIGN
11
5
397
397
23
2021
The transient receptor potential melastatin (TRPM) family belongs to the superfamily of TRP ion channels. It consists of eight family members that are involved in a plethora of cellular functions. TRPM2 is a homotetrameric Ca2+-permeable cation channel activated upon oxidative stress and is important, among others, for body heat control, immune cell activation and insulin secretion. Invertebrate TRPM2 proteins are channel enzymes; they hydrolyze the activating ligand, ADP-ribose, which is likely important for functional regulation. Since its cloning in 1998, the understanding of the biophysical properties of the channel has greatly advanced due to a vast number of structure– function studies. The physiological regulators of the channel have been identified and characterized in cell-free systems. In the wake of the recent structural biochemistry revolution, several TRPM2 cryo-EM structures have been published. These structures have helped to understand the general features of the channel, but at the same time have revealed unexplained mechanistic differences among channel orthologues. The present review aims at depicting the major research lines in TRPM2 structure-function. It discusses biophysical properties of the pore and the mode of action of direct channel effectors, and interprets these functional properties on the basis of recent three-dimensional structural models. © 2021 by the author. Licensee MDPI, Basel, Switzerland.
Funding
2010102
/api/funding/2010102
false
true
Funding
2010103
/api/funding/2010103
false
true
true
2021
true
true
true
false
true
false
GOLD
2024-02-21
true
https://doi.org/10.3390/life11050397
9
0
9
8
2
9
9
9
6
9
9
8
8
8
1
0
9
8
9
8
0
11
11
Q2
false
10020191
false
false
false
2021-05-27T11:33:04.633+0000
Biokémiai Tanszék (SE / AOK / I / BMBI); HCEMM-SE Molekuláris Csatornabetegségek Kutatóc... (SE / AOK / I / BMBI / BT); MTA-SE Lendület Ioncsatorna Kutatócsoport (SE / AOK / I / BMBI / BT)
1
10
3
1
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
96445875
/api/authorship/96445875
1
1.0
true
false
true
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A.
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
18846969
/api/publicationidentifier/18846969
GOLD
true
IDENTICAL
10.3390/life11050397
https://doi.org/10.3390/life11050397
false
true
PublicationIdentifier
18926098
/api/publicationidentifier/18926098
IDENTICAL
000654116000001
https://www.webofscience.com/wos/woscc/full-record/000654116000001
true
true
PublicationIdentifier
18846968
/api/publicationidentifier/18846968
IDENTICAL
85105782082
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85105782082
false
true
PublicationIdentifier
18926107
/api/publicationidentifier/18926107
IDENTICAL
33925466
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33925466&dopt=Abstract
false
true
Keyword
2282
/api/keyword/2282
true
2282
true
Keyword
1014845
/api/keyword/1014845
true
1014845
true
Keyword
1507502
/api/keyword/1507502
true
true
Keyword
1533642
/api/keyword/1533642
true
true
Keyword
1711741
/api/keyword/1711741
true
true
SjrRating
11195856
/api/sjrrating/11195856
102
0.49
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1301
/api/classificationexternal/1301
true
1301
true
Q2
DIRECT
true
true
/api/publication/32040119
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A. ✉</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;32040119" mtid="32040119" target="_blank">Two decades of evolution of our understanding of the transient receptor potential melastatin 2 (Trpm2) cation channel</a></div> <div class="pub-info"> <span class="journal-title">LIFE-BASEL</span> <span class="journal-volume">11</span> : <span class="journal-issue">5</span> <span class="page"> Paper: 397 , 23 p. </span> <span class="year">(2021)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/life11050397" target="_blank" href="https://doi.org/10.3390/life11050397"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000654116000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000654116000001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85105782082" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85105782082"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="33925466" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33925466&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:32040119 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Survey paper ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 9</span> | Independent citation: 8 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 9 | Number of citations in Scopus: 6 | WoS/Scopus assigned: 9 | Number of citations with DOI: 9 </div> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" mtid="10020191"><a
href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A. ✉
(<span class="authorship-author-name">Szöllősi András</span>
<span class="authorAux-mtmt"> Biokémia</span>)
</a>
</span>
<span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/MTA-SE Ion Channel Research Group; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Biokémiai Tanszék; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/<span title="Biokémiai Tanszék">BT</span>/HCEMM-SU Molecular Channelopathies Research Group</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;32040119" target="_blank">Two decades of evolution of our understanding of the transient receptor potential melastatin 2 (Trpm2) cation channel</a></div> <div> <span class="journal-title">LIFE-BASEL</span>
<span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2075-1729">2075-1729</a>)</span>:
<span class="journal-volume">11</span> <span class="journal-issue">5</span>
<span class="page">
Paper 397.
23 p.
</span> <span class="year">(2021)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Language:
English
| </span>
<span class="identifiers">
<span class="id identifier oa_GOLD" title=" Gold
">
<a style="color:blue" title="10.3390/life11050397" target="_blank" href="https://doi.org/10.3390/life11050397">
DOI
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="000654116000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000654116000001">
WoS
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="85105782082" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85105782082">
Scopus
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="33925466" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33925466&dopt=Abstract">
PubMed
</a>
</span>
</span>
<div class="publication-citation" style="margin-left: 0.5cm;">
<span title="" class="citingPub-count">Citing papers: 9</span>
| Independent citation: 8
| Self citation: 1
| Unknown citation: 0
| Number of citations in WoS: 9
| Number of citations in Scopus: 6
| WoS/Scopus assigned: 9
| Number of citations with DOI: 9
</div>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;32040119&sort=publishedYear,desc&sort=title">
Number of cited publications: 11
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Publication: 32040119</span>
| <span class="status-data status-VALIDATED"> Validated
</span>
Core Citing
| <span class="type-subtype">Journal Article
( Survey paper
)
</span>
| <span class="pub-category">Scientific</span>
| <span class="publication-sourceOfData">Scopus</span>
</div>
<div class="funder"> (LP2017-14/2017), Establishing the Hungarian Center of Excellence for Molecular Medicine in partnership with EMBL(739593) Funder: Horizon 2020 </div>
<div class="lastModified">Last Modified: 2023.11.29. 15:38 Márta Molnár-Taga (SE 4-es admin)
</div>
<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Department of Medical Biochemistry, Semmelweis University, Budapest, 1085, Hungary
MTA-SE Lendület Ion Channel Research Group, Semmelweis University, Budapest, 1085, Hungary
HCEMM-SE Molecular Channelopathies Research Group, Semmelweis University, Budapest, 1085, Hungary
Cited By :2
Export Date: 9 Ma...</pre>
</div></div>
JournalArticle
30637149
VALIDATED
true
Funding Agency and Grant Number: Howard Hughes Medical InstituteHoward Hughes Medical Institute; Magyar Tudomanyos Akademia [LP2017-14/2017]; Ministry of Human Capacities of Hungary [UNKP 17-4-I-SE-61, UNKP 18-4-SE-132]; Magyar Tudomanyos Akademia
Funding text: Howard Hughes Medical Institute International Early Career Scientist Award Laszlo Csanady; Magyar Tudomanyos Akademia LP2017-14/2017 Laszlo Csanady; Ministry of Human Capacities of Hungary UNKP 17-4-I-SE-61 Balazs Toth; Magyar Tudomanyos Akademia Bolyai Research Fellowship Balazs Toth; Ministry of Human Capacities of Hungary UNKP-FIKP Laszlo Csanady; Ministry of Human Capacities of Hungary UNKP 18-4-SE-132 Balazs Toth; The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.
Export Date: 7 January 2020
Correspondence Address: Csanády, L.; Department of Medical Biochemistry, Semmelweis UniversityHungary; email: csanady.laszlo@med.semmelweis-univ.hu
Export Date: 8 January 2020
Correspondence Address: Csanády, L.; Department of Medical Biochemistry, Semmelweis UniversityHungary; email: csanady.laszlo@med.semmelweis-univ.hu
0
false
2024-02-20T00:04:55.348+0000
2021-04-07T09:55:27.347+0000
2019-04-17T13:38:23.393+0000
true
10054198
xBökönyi
Zita
/api/admin/10054198
Admin
true
10054198
2023-02-24T10:10:52.469+0000
2019-09-23T10:03:26.437+0000
true
10015544
Csajbók
Edit
/api/admin/10015544
Admin
true
10015544
2019-10-03T09:03:28.735+0000
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Iordanov, Iordan
Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates
true
true
/api/journal/10031024
REVIEWED
true
false
10031024
false
10031024
true
2050-084X
2050-084X
Journal
FOREIGN
8
2019
e44556
e44556
23
2019
Transient Receptor Potential Melastatin 2 (TRPM2) is a cation channel important for the immune response, insulin secretion, and body temperature regulation. It is activated by cytosolic ADP ribose (ADPR) and contains a nudix-type motif 9 (NUDT9)-homology (NUDT9-H) domain homologous to ADPR phosphohydrolases (ADPRases). Human TRPM2 (hsTRPM2) is catalytically inactive due to mutations in the conserved Nudix box sequence. Here, we show that TRPM2 Nudix motifs are canonical in all invertebrates but vestigial in vertebrates. Correspondingly, TRPM2 of the cnidarian Nematostella vectensis (nvTRPM2) and the choanoflagellate Salpingoeca rosetta (srTRPM2) are active ADPRases. Disruption of ADPRase activity fails to affect nvTRPM2 channel currents, reporting a catalytic cycle uncoupled from gating. Furthermore, pore sequence substitutions responsible for inactivation of hsTRPM2 also appeared in vertebrates. Correspondingly, zebrafish (Danio rerio) TRPM2 (drTRPM2) and hsTRPM2 channels inactivate, but srTRPM2 and nvTRPM2 currents are stable. Thus, catalysis and pore stability were lost simultaneously in vertebrate TRPM2 channels.
2019
true
true
true
false
true
false
GOLD
2024-02-20
true
https://doi.org/10.7554/eLife.44556
17
0
17
12
5
17
17
17
16
17
17
12
12
12
5
0
17
12
17
12
0
7
7
D1
false
10015499,10020191,10052053
false
false
false
2019-07-16T13:47:50.049+0000
MTA-SE Lendület Ioncsatorna Kutatócsoport (SE / AOK / I / BMBI / BT); Orvosi Biokémiai Intézet (SE / AOK / I)
4
15
2
4
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
86786446
/api/authorship/86786446
1
0.25
true
false
false
Author
10052053
/api/author/10052053
Iordanov
Iordan
true
10052053
true
Iordanov
Iordan
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
86786447
/api/authorship/86786447
2
0.25
true
false
false
Author
10024493
/api/author/10024493
Tóth
Balázs
true
10024493
true
Tóth
Balázs
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
86786448
/api/authorship/86786448
3
0.25
false
false
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
Andras
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
86786449
/api/authorship/86786449
4
0.25
false
true
true
Author
10015499
/api/author/10015499
Csanády
László
true
10015499
true
Csanády
László
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
15554121
/api/publicationidentifier/15554121
GOLD
true
IDENTICAL
10.7554/eLife.44556
https://doi.org/10.7554/eLife.44556
false
true
PublicationIdentifier
15879442
/api/publicationidentifier/15879442
GREEN
true
98903
http://real.mtak.hu/98903
false
true
PublicationIdentifier
15879441
/api/publicationidentifier/15879441
GREEN
true
IDENTICAL
7628
https://repo.lib.semmelweis.hu/handle/123456789/7628
false
true
PublicationIdentifier
15583074
/api/publicationidentifier/15583074
IDENTICAL
000464410300001
https://www.webofscience.com/wos/woscc/full-record/000464410300001
false
true
PublicationIdentifier
15839482
/api/publicationidentifier/15839482
IDENTICAL
85064725932
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85064725932
false
true
PublicationIdentifier
15554120
/api/publicationidentifier/15554120
IDENTICAL
30938679
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30938679&dopt=Abstract
false
true
Classification
10619
/api/classification/10619
true
true
Classification
10578
/api/classification/10578
true
true
Classification
10610
/api/classification/10610
true
true
Keyword
7673
/api/keyword/7673
true
7673
true
Keyword
1028508
/api/keyword/1028508
true
1028508
true
Keyword
1066395
/api/keyword/1066395
true
1066395
true
Keyword
1175577
/api/keyword/1175577
true
1175577
true
Keyword
1510500
/api/keyword/1510500
true
true
Keyword
1711740
/api/keyword/1711740
true
true
Keyword
1711741
/api/keyword/1711741
true
true
Keyword
1711742
/api/keyword/1711742
true
true
Keyword
1711743
/api/keyword/1711743
true
true
SjrRating
10751781
/api/sjrrating/10751781
7
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1301
/api/classificationexternal/1301
true
1301
true
D1
DIRECT
true
true
/api/publication/30637149
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10052053"> <a href="/gui2/?type=authors&mode=browse&sel=10052053" target="_blank">Iordanov, Iordan</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10024493"> <a href="/gui2/?type=authors&mode=browse&sel=10024493" target="_blank">Tóth, Balázs<sup>*</sup></a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, Andras</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10015499"> <a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády, László ✉</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;30637149" mtid="30637149" target="_blank">Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates</a></div> <div class="pub-info"> <span class="journal-title">ELIFE</span> <span class="journal-volume">8</span> : <span class="journal-issue">2019</span> <span class="page"> Paper: e44556 , 23 p. </span> <span class="year">(2019)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.7554/eLife.44556" target="_blank" href="https://doi.org/10.7554/eLife.44556"> DOI </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="98903" target="_blank" href="http://real.mtak.hu/98903"> REAL </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="7628" target="_blank" href="https://repo.lib.semmelweis.hu/handle/123456789/7628"> SE Repozitórium </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000464410300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000464410300001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85064725932" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85064725932"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="30938679" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30938679&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:30637149 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 17</span> | Independent citation: 12 | Self citation: 5 | Unknown citation: 0 | Number of citations in WoS: 17 | Number of citations in Scopus: 16 | WoS/Scopus assigned: 17 | Number of citations with DOI: 17 </div> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" mtid="10052053"><a
href="/gui2/?type=authors&mode=browse&sel=10052053" target="_blank">Iordanov Iordan
(<span class="authorship-author-name">Iordanov Iordan</span>
<span class="authorAux-mtmt"> biokémia</span>)
</a>
</span>
<span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Medical Biochemistry">DMB</span>/MTA-SE Ion Channel Research Group</span>
;
<span class="author-name" mtid="10024493"><a
href="/gui2/?type=authors&mode=browse&sel=10024493" target="_blank">Tóth Balázs<sup>*</sup>
(<span class="authorship-author-name">Tóth Balázs</span>
<span class="authorAux-mtmt"> elektrofiziológia</span>)
</a>
</span>
<span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Medical Biochemistry">DMB</span>/MTA-SE Ion Channel Research Group</span>
;
<span class="author-name" mtid="10020191"><a
href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi Andras
(<span class="authorship-author-name">Szöllősi András</span>
<span class="authorAux-mtmt"> Biokémia</span>)
</a>
</span>
<span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Medical Biochemistry">DMB</span>/MTA-SE Ion Channel Research Group</span>
;
<span class="author-name" mtid="10015499"><a
href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády László ✉
(<span class="authorship-author-name">Csanády László</span>
<span class="authorAux-mtmt"> Biokémia</span>)
</a>
</span>
<span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Medical Biochemistry">DMB</span>/MTA-SE Ion Channel Research Group</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;30637149" target="_blank">Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates</a></div> <div> <span class="journal-title">ELIFE</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2050-084X">2050-084X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2050-084X">2050-084X</a>)</span>:
<span class="journal-volume">8</span> <span class="journal-issue">2019</span>
<span class="page">
Paper e44556.
23 p.
</span> <span class="year">(2019)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Language:
English
| </span>
<span class="identifiers">
<span class="id identifier oa_GOLD" title=" Gold
">
<a style="color:blue" title="10.7554/eLife.44556" target="_blank" href="https://doi.org/10.7554/eLife.44556">
DOI
</a>
</span>
<span class="id identifier oa_GREEN" title=" Green
">
<a style="color:black" title="98903" target="_blank" href="http://real.mtak.hu/98903">
REAL
</a>
</span>
<span class="id identifier oa_GREEN" title=" Green
">
<a style="color:blue" title="7628" target="_blank" href="https://repo.lib.semmelweis.hu/handle/123456789/7628">
SE Repozitórium
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="000464410300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000464410300001">
WoS
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="85064725932" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85064725932">
Scopus
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="30938679" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30938679&dopt=Abstract">
PubMed
</a>
</span>
</span>
<div class="publication-citation" style="margin-left: 0.5cm;">
<span title="" class="citingPub-count">Citing papers: 17</span>
| Independent citation: 12
| Self citation: 5
| Unknown citation: 0
| Number of citations in WoS: 17
| Number of citations in Scopus: 16
| WoS/Scopus assigned: 17
| Number of citations with DOI: 17
</div>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;30637149&sort=publishedYear,desc&sort=title">
Number of cited publications: 7
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Publication: 30637149</span>
| <span class="status-data status-VALIDATED"> Validated
</span>
Core Citing
| <span class="type-subtype">Journal Article
( Article
)
</span>
| <span class="pub-category">Scientific</span>
| <span class="publication-sourceOfData">PubMed (pubmed_result (29).xml, 2019-04-17)</span>
</div>
<div class="lastModified">Last Modified: 2021.04.07. 11:55 Zita xBökönyi (INAKTÍV_SE_AOK_OBI_Admin5_BZ, admin)
</div>
<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Funding Agency and Grant Number: Howard Hughes Medical InstituteHoward Hughes Medical Institute; Magyar Tudomanyos Akademia [LP2017-14/2017]; Ministry of Human Capacities of Hungary [UNKP 17-4-I-SE-61, UNKP 18-4-SE-132]; Magyar Tudomanyos Akademia
Funding text: Howard Hughes Medical Institute International Early Career Scientist Award Laszlo Csanady; Magyar Tudomanyos Akademia LP201...</pre>
</div></div>
JournalArticle
30465914
VALIDATED
true
0
false
2024-03-21T12:04:07.228+0000
2021-04-07T12:43:53.037+0000
2019-02-26T05:51:14.177+0000
true
565
WoS
import
/api/admin/565
Admin
true
2021-04-07T12:43:53.054+0000
2021-04-07T12:43:53.054+0000
2020-01-07T21:48:58.337+0000
true
10015544
Csajbók
Edit
/api/admin/10015544
Admin
true
10015544
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Zhang, Zhe
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation
true
true
/api/journal/10031024
REVIEWED
true
false
10031024
false
10031024
true
2050-084X
2050-084X
Journal
FOREIGN
7
e36409
e36409
22
2018
Transient receptor potential melastatin 2 (TRPM2) is a Ca2+-permeable cation channel required for immune cell activation, insulin secretion, and body heat control. TRPM2 is activated by cytosolic Ca2+, phosphatidyl-inositol-4,5-bisphosphate and ADP ribose. Here, we present the 3 A resolution electron cryo-microscopic structure of TRPM2 from Nematostella vectensis, 63% similar in sequence to human TRPM2, in the Ca2+-bound closed state. Compared to other TRPM channels, TRPM2 exhibits unique structural features that correlate with its function. The pore is larger and more negatively charged, consistent with its high Ca2+ selectivity and larger conductance. The intracellular Ca2+ binding sites are connected to the pore and cytosol, explaining the unusual dependence of TRPM2 activity on intra- and extracellular Ca2+. In addition, the absence of a post filter motif is likely the cause of the rapid inactivation of human TRPM2. Together, our cryo-EM and electrophysiology studies provide a molecular understanding of the unique gating mechanism of TRPM2.
2019
true
true
true
false
true
false
GOLD
2024-03-21
true
https://doi.org/10.7554/eLife.36409
107
0
107
102
5
107
104
103
99
107
107
102
102
102
5
0
107
102
107
102
0
6
6
D1
false
10015499,10024493,10020191
false
false
false
2019-07-22T12:13:42.098+0000
MTA-SE Lendület Ioncsatorna Kutatócsoport (SE / AOK / I / BMBI / BT); Orvosi Biokémiai Intézet (SE / AOK / I)
3
15
2
5
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
85575241
/api/authorship/85575241
1
0.2
true
false
true
Zhang
Zhe
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
85575242
/api/authorship/85575242
2
0.2
true
false
Author
10024493
/api/author/10024493
Tóth
Balázs
true
10024493
true
Tóth
Balázs
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
85575243
/api/authorship/85575243
3
0.2
false
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
Andras
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
85575244
/api/authorship/85575244
4
0.2
false
false
Chen
Jue
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
85575245
/api/authorship/85575245
5
0.2
false
true
true
Author
10015499
/api/author/10015499
Csanády
László
true
10015499
true
Csanády
László
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
15245748
/api/publicationidentifier/15245748
GOLD
true
IDENTICAL
10.7554/eLife.36409
https://doi.org/10.7554/eLife.36409
false
true
PublicationIdentifier
15245747
/api/publicationidentifier/15245747
IDENTICAL
000433414600001
https://www.webofscience.com/wos/woscc/full-record/000433414600001
false
true
PublicationIdentifier
1315875
/api/publicationidentifier/1315875
false
IDENTICAL
85048315733
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85048315733
false
1822457
true
PublicationIdentifier
1315877
/api/publicationidentifier/1315877
false
IDENTICAL
29745897
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29745897&dopt=Abstract
false
1810648
true
PublicationIdentifier
1315878
/api/publicationidentifier/1315878
false
IDENTICAL
PMC5976436
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976436
false
1810647
true
Classification
10619
/api/classification/10619
true
true
Classification
10610
/api/classification/10610
true
true
Classification
10595
/api/classification/10595
true
true
SjrRating
10751786
/api/sjrrating/10751786
9
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1301
/api/classificationexternal/1301
true
1301
true
D1
DIRECT
true
true
/api/publication/30465914
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Zhang, Zhe ✉ </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10024493"> <a href="/gui2/?type=authors&mode=browse&sel=10024493" target="_blank">Tóth, Balázs<sup>*</sup></a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, Andras</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Chen, Jue </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10015499"> <a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády, László ✉</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;30465914" mtid="30465914" target="_blank">Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation</a></div> <div class="pub-info"> <span class="journal-title">ELIFE</span> <span class="journal-volume">7</span> <span class="page"> Paper: e36409 , 22 p. </span> <span class="year">(2018)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.7554/eLife.36409" target="_blank" href="https://doi.org/10.7554/eLife.36409"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000433414600001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000433414600001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85048315733" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85048315733"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="29745897" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29745897&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="PMC5976436" target="_blank" href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976436"> Pubmed Central </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:30465914 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 107</span> | Independent citation: 102 | Self citation: 5 | Unknown citation: 0 | Number of citations in WoS: 103 | Number of citations in Scopus: 99 | WoS/Scopus assigned: 107 | Number of citations with DOI: 104 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Zhang Zhe ✉ </span> ; <span class="author-name" mtid="10024493"><a href="/gui2/?type=authors&mode=browse&sel=10024493" target="_blank">Tóth Balázs<sup>*</sup> (<span class="authorship-author-name">Tóth Balázs</span> <span class="authorAux-mtmt"> elektrofiziológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Medical Biochemistry">DMB</span>/MTA-SE Ion Channel Research Group</span> ; <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi Andras (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Medical Biochemistry">DMB</span>/MTA-SE Ion Channel Research Group</span> ; <span class="author-name" >Chen Jue </span> ; <span class="author-name" mtid="10015499"><a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády László ✉ (<span class="authorship-author-name">Csanády László</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Medical Biochemistry">DMB</span>/MTA-SE Ion Channel Research Group</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;30465914" target="_blank">Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation</a></div> <div> <span class="journal-title">ELIFE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2050-084X">2050-084X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2050-084X">2050-084X</a>)</span>: <span class="journal-volume">7</span> <span class="page"> Paper e36409. 22 p. </span> <span class="year">(2018)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.7554/eLife.36409" target="_blank" href="https://doi.org/10.7554/eLife.36409"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000433414600001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000433414600001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85048315733" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85048315733"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="29745897" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29745897&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="PMC5976436" target="_blank" href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976436"> Pubmed Central </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 107</span> | Independent citation: 102 | Self citation: 5 | Unknown citation: 0 | Number of citations in WoS: 103 | Number of citations in Scopus: 99 | WoS/Scopus assigned: 107 | Number of citations with DOI: 104 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;30465914&sort=publishedYear,desc&sort=title"> Number of cited publications: 6 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 30465914</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WoS XML</span> </div> <div class="lastModified">Last Modified: 2021.04.07. 14:43 Zita xBökönyi (INAKTÍV_SE_AOK_OBI_Admin5_BZ, admin) </div> </div></div>
JournalArticle
3110723
VALIDATED
true
0
2017-04-07T13:13:10.000+0000
false
3110723
2024-02-18T13:16:29.681+0000
2022-05-17T12:32:58.494+0000
2016-09-13T09:28:00.000+0000
true
10020191
Szöllősi
András
/api/author/10020191
Author
true
10020191
2022-05-17T12:32:34.443+0000
2022-05-17T12:32:34.443+0000
2022-05-17T12:32:58.698+0000
true
10015544
Csajbók
Edit
/api/admin/10015544
Admin
true
10015544
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Szollosi, A
Dissecting the Molecular Mechanism of Nucleotide-Dependent Activation of the KtrAB K+ Transporter
true
true
/api/journal/10001349
REVIEWED
true
false
10001349
false
10001349
true
1544-9173
1545-7885
Journal
FOREIGN
14
1
e1002356
e1002356
2016
KtrAB belongs to the Trk/Ktr/HKT superfamily of monovalent cation (K+ and Na+) transport proteins that closely resemble K+ channels. These proteins underlie a plethora of cellular functions that are crucial for environmental adaptation in plants, fungi, archaea, and bacteria. The activation mechanism of the Trk/Ktr/HKT proteins remains unknown. It has been shown that ATP stimulates the activity of KtrAB while ADP does not. Here, we present X-ray structural information on the KtrAB complex with bound ADP. A comparison with the KtrAB-ATP structure reveals conformational changes in the ring and in the membrane protein. In combination with a biochemical and functional analysis, we uncover how ligand-dependent changes in the KtrA ring are propagated to the KtrB membrane protein and conclude that, despite their structural similarity, the activation mechanism of KtrAB is markedly different from the activation mechanism of K+ channels. © 2016 Szollosi et al.
2016
(Bökönyi Zita; 2016.09.13. 11:27:14)
true
true
true
false
true
false
GOLD
2024-02-18
true
https://doi.org/10.1371/journal.pbio.1002356
true
10054198
xBökönyi
Zita
/api/admin/10054198
Admin
true
10054198
19
0
19
18
0
19
19
19
17
19
19
18
18
18
1
0
19
18
19
18
0
1
1
D1
false
10020191
false
false
false
2016-12-12T10:34:33.000+0000
2016-09-13T09:34:33.000+0000
Orvosi Biokémiai Intézet (SE / AOK / I)
1
10
1
5
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
8236525
/api/authorship/8236525
1
0.125
true
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
24764570
true
PersonAuthorship
8236527
/api/authorship/8236527
2
0.125
false
false
Vieira-Pires
Ricardo S
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
24764569
true
PersonAuthorship
8236529
/api/authorship/8236529
3
0.125
false
false
Teixeira-Duarte
Celso M
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
24764568
true
PersonAuthorship
8236530
/api/authorship/8236530
4
0.125
false
false
Rocha
R
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
24764567
true
PersonAuthorship
8236532
/api/authorship/8236532
5
0.125
false
true
true
Morais-Cabral
Joao H
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
24764566
true
PublicationIdentifier
1125663
/api/publicationidentifier/1125663
GOLD
true
IDENTICAL
10.1371/journal.pbio.1002356
https://doi.org/10.1371/journal.pbio.1002356
false
1453688
true
PublicationIdentifier
15029244
/api/publicationidentifier/15029244
IDENTICAL
000371882900022
https://www.webofscience.com/wos/woscc/full-record/000371882900022
false
11901308
true
PublicationIdentifier
1125662
/api/publicationidentifier/1125662
false
IDENTICAL
84961353773
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84961353773
false
1453687
true
PublicationIdentifier
20992500
/api/publicationidentifier/20992500
IDENTICAL
26771197
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=26771197&dopt=Abstract
false
true
Classification
12125
/api/classification/12125
true
true
Classification
10545
/api/classification/10545
true
true
Classification
12713
/api/classification/12713
true
true
Keyword
1699
/api/keyword/1699
true
1699
true
Keyword
4511
/api/keyword/4511
true
4511
true
Keyword
4608
/api/keyword/4608
true
4608
true
Keyword
5079
/api/keyword/5079
true
5079
true
Keyword
8074
/api/keyword/8074
true
8074
true
Keyword
14267
/api/keyword/14267
true
14267
true
Keyword
14328
/api/keyword/14328
true
14328
true
Keyword
14385
/api/keyword/14385
true
14385
true
Keyword
14604
/api/keyword/14604
true
14604
true
Keyword
19707
/api/keyword/19707
true
19707
true
Keyword
19963
/api/keyword/19963
true
19963
true
Keyword
1002342
/api/keyword/1002342
true
1002342
true
Keyword
1009055
/api/keyword/1009055
true
1009055
true
Keyword
1009102
/api/keyword/1009102
true
1009102
true
Keyword
1009571
/api/keyword/1009571
true
1009571
true
Keyword
1013420
/api/keyword/1013420
true
1013420
true
Keyword
1032205
/api/keyword/1032205
true
1032205
true
Keyword
1034643
/api/keyword/1034643
true
1034643
true
Keyword
1183633
/api/keyword/1183633
true
1183633
true
Keyword
1414650
/api/keyword/1414650
true
1414650
true
Keyword
1414651
/api/keyword/1414651
true
1414651
true
SjrRating
10911934
/api/sjrrating/10911934
3
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1101
/api/classificationexternal/1101
true
1101
true
D1
DIRECT
true
true
/api/publication/3110723
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Vieira-Pires, Ricardo S </span> <span class="author-type"> </span> ; <span class="author-name" > Teixeira-Duarte, Celso M </span> <span class="author-type"> </span> ; <span class="author-name" > Rocha, R </span> <span class="author-type"> </span> ; <span class="author-name" > Morais-Cabral, Joao H ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;3110723" mtid="3110723" target="_blank">Dissecting the Molecular Mechanism of Nucleotide-Dependent Activation of the KtrAB K+ Transporter</a></div> <div class="pub-info"> <span class="journal-title">PLOS BIOLOGY</span> <span class="journal-volume">14</span> : <span class="journal-issue">1</span> <span class="page"> Paper: e1002356 </span> <span class="year">(2016)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1371/journal.pbio.1002356" target="_blank" href="https://doi.org/10.1371/journal.pbio.1002356"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000371882900022" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000371882900022"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84961353773" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84961353773"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="26771197" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=26771197&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:3110723 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 19</span> | Independent citation: 18 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 19 | Number of citations in Scopus: 17 | WoS/Scopus assigned: 19 | Number of citations with DOI: 19 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry</span> ; <span class="author-name" >Vieira-Pires Ricardo S </span> ; <span class="author-name" >Teixeira-Duarte Celso M </span> ; <span class="author-name" >Rocha R </span> ; <span class="author-name" >Morais-Cabral Joao H ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;3110723" target="_blank">Dissecting the Molecular Mechanism of Nucleotide-Dependent Activation of the KtrAB K+ Transporter</a></div> <div> <span class="journal-title">PLOS BIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1544-9173">1544-9173</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1545-7885">1545-7885</a>)</span>: <span class="journal-volume">14</span> <span class="journal-issue">1</span> <span class="page"> Paper e1002356. </span> <span class="year">(2016)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1371/journal.pbio.1002356" target="_blank" href="https://doi.org/10.1371/journal.pbio.1002356"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000371882900022" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000371882900022"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84961353773" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84961353773"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="26771197" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=26771197&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 19</span> | Independent citation: 18 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 19 | Number of citations in Scopus: 17 | WoS/Scopus assigned: 19 | Number of citations with DOI: 19 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;3110723&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 3110723</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 3110723</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Last Modified: 2022.05.17. 14:32 Edit Csajbók (SE_KK_Admin5_CSE, admin) </div> </div></div>
JournalArticle
2333381
VALIDATED
true
0
2014-12-24T11:24:32.000+0000
false
2333381
2024-02-17T01:55:35.314+0000
2023-09-02T14:35:42.444+0000
2013-06-12T08:03:06.000+0000
true
10015499
Csanády
László
/api/author/10015499
Author
true
10015499
2022-08-26T07:27:06.327+0000
2023-09-02T14:35:42.792+0000
true
10039043
Milánkovics
Róbert
/api/admin/10039043
Admin
true
10039043
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Csanády, L
Conformational changes in the catalytically inactive nucleotide-binding site of CFTR
true
true
/api/journal/2517
REVIEWED
true
false
2517
false
2517
true
0022-1295
1540-7748
Journal
FOREIGN
142
1
61
73
61
13
2013
A central step in the gating of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is the association of its two cytosolic nucleotide-binding domains (NBDs) into a head-to-tail dimer, with two nucleotides bound at the interface. Channel opening and closing, respectively, are coupled to formation and disruption of this tight NBD dimer. CFTR is an asymmetric adenosine triphosphate (ATP)-binding cassette protein in which the two interfacial-binding sites (composite sites 1 and 2) are functionally different. During gating, the canonical, catalytically active nucleotide-binding site (site 2) cycles between dimerized prehydrolytic (state O1), dimerized post-hydrolytic (state O2), and dissociated (state C) forms in a preferential C-->O1-->O2-->C sequence. In contrast, the catalytically inactive nucleotide-binding site (site 1) is believed to remain associated, ATP-bound, for several gating cycles. Here, we have examined the possibility of conformational changes in site 1 during gating, by studying gating effects of perturbations in site 1.Previous work showed that channel closure is slowed, both under hydrolytic and nonhydrolytic conditions, by occupancy of site 1 by N6-(2-phenylethyl)-ATP (P-ATP) as well as by the site-1 mutation H1348A (NBD2 signature sequence). Here, we found that P-ATP prolongs wild-type (WT) CFTR burst durations by selectively slowing (>2x) transition O1-->O2 and decreases the nonhydrolytic closing rate (transition O1-->C) of CFTR mutants K1250A ( approximately 4x) and E1371S ( approximately 3x). Mutation H1348A also slowed ( approximately 3x) the O1-->O2 transition in the WT background and decreased the nonhydrolytic closing rate of both K1250A ( approximately 3x) and E1371S ( approximately 3x) background mutants. Neither P-ATP nor the H1348A mutation affected the 1:1 stoichiometry between ATP occlusion and channel burst events characteristic to WT CFTR gating in ATP. The marked effect that different structural perturbations at site 1 have on both steps O1-->C and O1-->O2 suggests that the overall conformational changes that CFTR undergoes upon opening and coincident with hydrolysis at the active site 2 include significant structural rearrangement at site 1.
2013
453133
true
true
true
false
true
false
GREEN
GREEN
2024-02-17
true
https://repo.lib.semmelweis.hu/handle/123456789/278
21
0
21
13
6
21
21
21
21
21
21
13
13
13
8
0
21
13
21
13
0
8
8
D1
false
10020191,10037593
false
false
false
2014-03-31T12:17:53.000+0000
2013-06-12T08:04:26.000+0000
MTA-SE Lendület Ioncsatorna Kutatócsoport (SE / AOK / I / BMBI / BT); Orvosi Biokémiai Intézet (SE / AOK / I)
4
21
2
5
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
4154919
/api/authorship/4154919
1
0.2
true
false
true
Author
10015499
/api/author/10015499
Csanády
László
true
10015499
true
Csanády
L
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
17862781
true
PersonAuthorship
4154920
/api/authorship/4154920
2
0.2
false
false
Author
10037593
/api/author/10037593
Mihályi
Csaba
true
10037593
true
Mihalyi
C
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
17862780
true
PersonAuthorship
4154921
/api/authorship/4154921
3
0.2
false
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
17862779
true
PersonAuthorship
4154922
/api/authorship/4154922
4
0.2
false
false
Author
10003430
/api/author/10003430
Törőcsik
Beáta
true
10003430
true
Torocsik
B
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
17862778
true
PersonAuthorship
4154923
/api/authorship/4154923
5
0.2
false
true
Vergani
P
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
17862777
true
PublicationIdentifier
677825
/api/publicationidentifier/677825
false
IDENTICAL
10.1085/jgp.201210954
https://doi.org/10.1085/jgp.201210954
false
437914
true
PublicationIdentifier
677827
/api/publicationidentifier/677827
false
IDENTICAL
7446
http://real.mtak.hu/7446
false
546356
true
PublicationIdentifier
677828
/api/publicationidentifier/677828
GREEN
true
IDENTICAL
278
https://repo.lib.semmelweis.hu/handle/123456789/278
false
908385
true
PublicationIdentifier
677823
/api/publicationidentifier/677823
false
IDENTICAL
000320774000005
https://www.webofscience.com/wos/woscc/full-record/000320774000005
false
640728
true
PublicationIdentifier
677824
/api/publicationidentifier/677824
false
IDENTICAL
84880024804
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84880024804
false
954095
true
PublicationIdentifier
677826
/api/publicationidentifier/677826
false
IDENTICAL
23752332
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=23752332&dopt=Abstract
false
437915
true
Classification
10619
/api/classification/10619
true
true
Classification
10610
/api/classification/10610
true
true
SjrRating
11156606
/api/sjrrating/11156606
11
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1314
/api/classificationexternal/1314
true
1314
true
D1
DIRECT
true
true
/api/publication/2333381
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10015499"> <a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády, L ✉</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10037593"> <a href="/gui2/?type=authors&mode=browse&sel=10037593" target="_blank">Mihalyi, C</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10003430"> <a href="/gui2/?type=authors&mode=browse&sel=10003430" target="_blank">Torocsik, B</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Vergani, P </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;2333381" mtid="2333381" target="_blank">Conformational changes in the catalytically inactive nucleotide-binding site of CFTR</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF GENERAL PHYSIOLOGY</span> <span class="journal-volume">142</span> : <span class="journal-issue">1</span> <span class="page"> pp. 61-73. , 13 p. </span> <span class="year">(2013)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1085/jgp.201210954" target="_blank" href="https://doi.org/10.1085/jgp.201210954"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="7446" target="_blank" href="http://real.mtak.hu/7446"> REAL </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="278" target="_blank" href="https://repo.lib.semmelweis.hu/handle/123456789/278"> SE Repozitórium </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000320774000005" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000320774000005"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84880024804" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84880024804"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="23752332" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=23752332&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:2333381 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 21</span> | Independent citation: 13 | Self citation: 8 | Unknown citation: 0 | Number of citations in WoS: 21 | Number of citations in Scopus: 21 | WoS/Scopus assigned: 21 | Number of citations with DOI: 21 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10015499"><a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády L ✉ (<span class="authorship-author-name">Csanády László</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Medical Biochemistry">DMB</span>/MTA-SE Ion Channel Research Group</span> ; <span class="author-name" mtid="10037593"><a href="/gui2/?type=authors&mode=browse&sel=10037593" target="_blank">Mihalyi C (<span class="authorship-author-name">Mihályi Csaba</span> <span class="authorAux-mtmt"> biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry</span> ; <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry</span> ; <span class="author-name" mtid="10003430"><a href="/gui2/?type=authors&mode=browse&sel=10003430" target="_blank">Torocsik B (<span class="authorship-author-name">Törőcsik Beáta</span> <span class="authorAux-mtmt"> orvosi biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry</span> ; <span class="author-name" >Vergani P </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;2333381" target="_blank">Conformational changes in the catalytically inactive nucleotide-binding site of CFTR</a></div> <div> <span class="journal-title">JOURNAL OF GENERAL PHYSIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0022-1295">0022-1295</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1540-7748">1540-7748</a>)</span>: <span class="journal-volume">142</span> <span class="journal-issue">1</span> <span class="page"> pp 61-73 </span> <span class="year">(2013)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1085/jgp.201210954" target="_blank" href="https://doi.org/10.1085/jgp.201210954"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="7446" target="_blank" href="http://real.mtak.hu/7446"> REAL </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="278" target="_blank" href="https://repo.lib.semmelweis.hu/handle/123456789/278"> SE Repozitórium </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000320774000005" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000320774000005"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84880024804" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84880024804"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="23752332" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=23752332&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 21</span> | Independent citation: 13 | Self citation: 8 | Unknown citation: 0 | Number of citations in WoS: 21 | Number of citations in Scopus: 21 | WoS/Scopus assigned: 21 | Number of citations with DOI: 21 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;2333381&sort=publishedYear,desc&sort=title"> Number of cited publications: 8 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 2333381</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 2333381</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Last Modified: 2023.09.02. 16:35 Róbert Milánkovics (PTE ÁOK admin 4) </div> </div></div>
JournalArticle
2329285
VALIDATED
true
0
2014-12-24T11:24:24.000+0000
false
2329285
2024-02-17T01:43:53.214+0000
2020-12-22T12:38:33.228+0000
2013-06-05T08:53:49.000+0000
true
10020191
Szöllősi
András
/api/author/10020191
Author
true
10020191
2018-10-20T17:03:24.888+0000
2018-10-20T17:03:24.888+0000
2014-09-23T12:30:45.000+0000
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
2014-09-23T12:30:45.000+0000
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Vieira-Pires, RS
The structure of the KtrAB potassium transporter
true
true
/api/journal/3308
REVIEWED
true
false
3308
false
3308
true
0028-0836
1476-4687
Journal
FOREIGN
496
7445
323
328
323
6
2013
In bacteria, archaea, fungi and plants the Trk, Ktr and HKT ion transporters are key components of osmotic regulation, pH homeostasis and resistance to drought and high salinity. These ion transporters are functionally diverse: they can function as Na + or K + channels and possibly as cation/K + symporters. They are closely related to potassium channels both at the level of the membrane protein and at the level of the cytosolic regulatory domains. Here we describe the crystal structure of a Ktr K + transporter, the KtrAB complex from Bacillus subtilis. The structure shows the dimeric membrane protein KtrB assembled with a cytosolic octameric KtrA ring bound to ATP, an activating ligand. A comparison between the structure of KtrAB-ATP and the structures of the isolated full-length KtrA protein with ATP or ADP reveals a ligand-dependent conformational change in the octameric ring, raising new ideas about the mechanism of activation in these transporters. © 2013 Macmillan Publishers Limited. All rights reserved.
2013
(Szőllősi András; 2013.06.05. 10:53:25)
true
true
true
false
false
NONE
2024-02-17
false
89
0
89
83
1
89
88
85
75
89
89
83
83
83
6
0
89
83
89
83
0
0
0
D1
A
false
10020191
false
false
false
2014-09-23T12:30:45.000+0000
2013-06-05T09:01:08.000+0000
1
10
0
3
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
4130425
/api/authorship/4130425
1
0.33333334
true
false
Vieira-Pires
RS
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
17830123
true
PersonAuthorship
4130426
/api/authorship/4130426
2
0.33333334
false
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
17830122
true
PersonAuthorship
4130427
/api/authorship/4130427
3
0.33333334
false
true
Morais-Cabral
JH
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
17830121
true
PublicationIdentifier
676090
/api/publicationidentifier/676090
false
IDENTICAL
10.1038/nature12055
https://doi.org/10.1038/nature12055
false
434202
true
PublicationIdentifier
676088
/api/publicationidentifier/676088
false
IDENTICAL
000317599200029
https://www.webofscience.com/wos/woscc/full-record/000317599200029
false
954106
true
PublicationIdentifier
676089
/api/publicationidentifier/676089
false
IDENTICAL
84876273276
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84876273276
false
434201
true
PublicationIdentifier
676091
/api/publicationidentifier/676091
false
IDENTICAL
23598340
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=23598340&dopt=Abstract
false
434203
true
Classification
10799
/api/classification/10799
true
true
Keyword
131
/api/keyword/131
true
131
true
Keyword
473
/api/keyword/473
true
473
true
Keyword
945
/api/keyword/945
true
945
true
Keyword
1699
/api/keyword/1699
true
1699
true
Keyword
2180
/api/keyword/2180
true
2180
true
Keyword
3533
/api/keyword/3533
true
3533
true
Keyword
4380
/api/keyword/4380
true
4380
true
Keyword
4450
/api/keyword/4450
true
4450
true
Keyword
4511
/api/keyword/4511
true
4511
true
Keyword
4585
/api/keyword/4585
true
4585
true
Keyword
4600
/api/keyword/4600
true
4600
true
Keyword
4946
/api/keyword/4946
true
4946
true
Keyword
5027
/api/keyword/5027
true
5027
true
Keyword
5079
/api/keyword/5079
true
5079
true
Keyword
7734
/api/keyword/7734
true
7734
true
Keyword
7808
/api/keyword/7808
true
7808
true
Keyword
8074
/api/keyword/8074
true
8074
true
Keyword
9987
/api/keyword/9987
true
9987
true
Keyword
12551
/api/keyword/12551
true
12551
true
Keyword
13689
/api/keyword/13689
true
13689
true
Keyword
14267
/api/keyword/14267
true
14267
true
Keyword
14385
/api/keyword/14385
true
14385
true
Keyword
14604
/api/keyword/14604
true
14604
true
Keyword
14684
/api/keyword/14684
true
14684
true
Keyword
15183
/api/keyword/15183
true
15183
true
Keyword
19963
/api/keyword/19963
true
19963
true
Keyword
1002688
/api/keyword/1002688
true
1002688
true
Keyword
1003890
/api/keyword/1003890
true
1003890
true
Keyword
1005199
/api/keyword/1005199
true
1005199
true
Keyword
1011419
/api/keyword/1011419
true
1011419
true
Keyword
1012128
/api/keyword/1012128
true
1012128
true
Keyword
1013420
/api/keyword/1013420
true
1013420
true
Keyword
1027316
/api/keyword/1027316
true
1027316
true
Keyword
1027985
/api/keyword/1027985
true
1027985
true
Keyword
1030039
/api/keyword/1030039
true
1030039
true
Keyword
1034634
/api/keyword/1034634
true
1034634
true
Keyword
1038064
/api/keyword/1038064
true
1038064
true
Keyword
1118347
/api/keyword/1118347
true
1118347
true
Keyword
1246350
/api/keyword/1246350
true
1246350
true
Keyword
1246351
/api/keyword/1246351
true
1246351
true
Keyword
1246352
/api/keyword/1246352
true
1246352
true
Keyword
1246353
/api/keyword/1246353
true
1246353
true
MtaRating
11435135
/api/mtarating/11435135
RatingType
10031
/api/ratingtype/10031
X. FTO
Institute
70
/api/institute/70
0
false
false
X. Földtudományok Osztálya
HAS Section of Earth Sciences (X.)
true
70
true
true
true
A
true
true
MtaRating
11551101
/api/mtarating/11551101
RatingType
10010
/api/ratingtype/10010
RegTB
Institute
14100
/api/institute/14100
0
false
true
Regionális Tudományok Bizottsága
Regionális Tudományok Bizottsága
true
14100
true
true
true
A nemzetközi
false
true
MtaRating
519065
/api/mtarating/519065
RatingType
10007
/api/ratingtype/10007
SZTB
Institute
14102
/api/institute/14102
0
false
true
Szociológiai Tudományos Bizottság
Szociológiai Tudományos Bizottság
true
14102
true
true
true
A nemzetközi
true
19065
true
SjrRating
11150537
/api/sjrrating/11150537
1
0.0
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1000
/api/classificationexternal/1000
true
1000
true
D1
DIRECT
true
true
/api/publication/2329285
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Vieira-Pires, RS </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Morais-Cabral, JH </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;2329285" mtid="2329285" target="_blank">The structure of the KtrAB potassium transporter</a></div> <div class="pub-info"> <span class="journal-title">NATURE</span> <span class="journal-volume">496</span> : <span class="journal-issue">7445</span> <span class="page"> pp. 323-328. , 6 p. </span> <span class="year">(2013)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1038/nature12055" target="_blank" href="https://doi.org/10.1038/nature12055"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000317599200029" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000317599200029"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84876273276" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84876273276"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="23598340" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=23598340&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:2329285 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 89</span> | Independent citation: 83 | Self citation: 6 | Unknown citation: 0 | Number of citations in WoS: 85 | Number of citations in Scopus: 75 | WoS/Scopus assigned: 89 | Number of citations with DOI: 88 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" >Vieira-Pires RS </span> ; <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> ; <span class="author-name" >Morais-Cabral JH </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;2329285" target="_blank">The structure of the KtrAB potassium transporter</a></div> <div> <span class="journal-title">NATURE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0028-0836">0028-0836</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1476-4687">1476-4687</a>)</span>: <span class="journal-volume">496</span> <span class="journal-issue">7445</span> <span class="page"> pp 323-328 </span> <span class="year">(2013)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1038/nature12055" target="_blank" href="https://doi.org/10.1038/nature12055"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000317599200029" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000317599200029"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84876273276" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84876273276"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="23598340" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=23598340&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 89</span> | Independent citation: 83 | Self citation: 6 | Unknown citation: 0 | Number of citations in WoS: 85 | Number of citations in Scopus: 75 | WoS/Scopus assigned: 89 | Number of citations with DOI: 88 </div> <div class="mtid"><span class="long-pub-mtid">Publication: 2329285</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 2329285</span> | Core | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Last Modified: 2020.12.22. 13:38 Admin Szuper (admin) </div> </div></div>
JournalArticle
1690126
VALIDATED
true
0
2014-11-18T16:17:37.000+0000
false
1690126
2024-02-16T00:48:32.807+0000
2021-05-14T08:42:00.967+0000
2011-09-05T13:20:05.000+0000
true
10015499
Csanády
László
/api/author/10015499
Author
true
10015499
2022-07-15T13:46:34.859+0000
2022-07-15T13:46:34.859+0000
2021-05-13T13:11:23.105+0000
true
10054198
xBökönyi
Zita
/api/admin/10054198
Admin
true
10054198
2021-05-14T08:42:00.978+0000
true
10054198
xBökönyi
Zita
/api/admin/10054198
Admin
true
10054198
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Szollosi, A
Mutant cycles at CFTR's non-canonical ATP-binding site support little interface separation during gating
true
true
/api/journal/2517
REVIEWED
true
false
2517
false
2517
true
0022-1295
1540-7748
Journal
FOREIGN
137
6
549
562
549
14
2011
2011
92820
true
true
true
false
true
false
NONE
2024-02-16
false
38
0
38
29
5
37
36
37
37
38
38
29
29
29
9
0
38
29
38
29
0
7
7
Q1
false
10020191
false
false
false
2014-09-24T11:09:55.000+0000
2013-02-23T19:18:00.000+0000
Orvosi Biokémiai Intézet (SE / AOK / I)
2
12
1
4
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
1902629
/api/authorship/1902629
1
0.25
true
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
13381877
true
PersonAuthorship
1902630
/api/authorship/1902630
2
0.25
true
false
Muallem
DR
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
13381876
true
PersonAuthorship
1902631
/api/authorship/1902631
3
0.25
false
false
Author
10015499
/api/author/10015499
Csanády
László
true
10015499
true
Csanády
L
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
13381875
true
PersonAuthorship
1902632
/api/authorship/1902632
4
0.25
false
true
true
Vergani
P
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
13381874
true
PublicationIdentifier
416701
/api/publicationidentifier/416701
false
IDENTICAL
10.1085/jgp.201110608
https://doi.org/10.1085/jgp.201110608
false
245690
true
PublicationIdentifier
416699
/api/publicationidentifier/416699
false
IDENTICAL
000291047100007
https://www.webofscience.com/wos/woscc/full-record/000291047100007
false
245691
true
PublicationIdentifier
416700
/api/publicationidentifier/416700
false
IDENTICAL
79958076650
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-79958076650
false
954115
true
PublicationIdentifier
416702
/api/publicationidentifier/416702
false
IDENTICAL
21576373
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=21576373&dopt=Abstract
false
954116
true
Classification
10619
/api/classification/10619
true
true
Classification
10610
/api/classification/10610
true
true
SjrRating
5692549
/api/sjrrating/5692549
25
0.24
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1314
/api/classificationexternal/1314
true
1314
true
Q1
DIRECT
true
5692549
true
/api/publication/1690126
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Muallem, DR<sup>*</sup> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10015499"> <a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády, L</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Vergani, P ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1690126" mtid="1690126" target="_blank">Mutant cycles at CFTR's non-canonical ATP-binding site support little interface separation during gating</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF GENERAL PHYSIOLOGY</span> <span class="journal-volume">137</span> : <span class="journal-issue">6</span> <span class="page"> pp. 549-562. , 14 p. </span> <span class="year">(2011)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1085/jgp.201110608" target="_blank" href="https://doi.org/10.1085/jgp.201110608"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000291047100007" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000291047100007"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="79958076650" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-79958076650"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="21576373" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=21576373&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:1690126 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 38</span> | Independent citation: 29 | Self citation: 9 | Unknown citation: 0 | Number of citations in WoS: 37 | Number of citations in Scopus: 37 | WoS/Scopus assigned: 38 | Number of citations with DOI: 36 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry</span> ; <span class="author-name" >Muallem DR<sup>*</sup> </span> ; <span class="author-name" mtid="10015499"><a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády L (<span class="authorship-author-name">Csanády László</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry</span> ; <span class="author-name" >Vergani P ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1690126" target="_blank">Mutant cycles at CFTR's non-canonical ATP-binding site support little interface separation during gating</a></div> <div> <span class="journal-title">JOURNAL OF GENERAL PHYSIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0022-1295">0022-1295</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1540-7748">1540-7748</a>)</span>: <span class="journal-volume">137</span> <span class="journal-issue">6</span> <span class="page"> pp 549-562 </span> <span class="year">(2011)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1085/jgp.201110608" target="_blank" href="https://doi.org/10.1085/jgp.201110608"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000291047100007" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000291047100007"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="79958076650" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-79958076650"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="21576373" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=21576373&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 38</span> | Independent citation: 29 | Self citation: 9 | Unknown citation: 0 | Number of citations in WoS: 37 | Number of citations in Scopus: 37 | WoS/Scopus assigned: 38 | Number of citations with DOI: 36 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1690126&sort=publishedYear,desc&sort=title"> Number of cited publications: 7 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 1690126</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 1690126</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Last Modified: 2021.05.14. 10:42 Zita xBökönyi (INAKTÍV_SE_AOK_OBI_Admin5_BZ, admin) </div> </div></div>
JournalArticle
1504152
VALIDATED
true
0
2014-10-16T16:19:11.000+0000
false
1504152
2024-02-15T20:23:55.873+0000
2018-10-09T09:59:41.618+0000
2011-04-20T10:42:28.000+0000
true
10020191
Szöllősi
András
/api/author/10020191
Author
true
10020191
2018-10-09T09:59:41.618+0000
2018-10-09T10:21:29.613+0000
2012-01-13T10:19:55.000+0000
true
10019992
Zsárik
Judit
/api/admin/10019992
Admin
true
10019992
2014-09-23T13:07:56.000+0000
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Szollosi, A
Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K plus channels
true
true
/api/journal/825
REVIEWED
true
false
825
false
825
true
0007-1188
1476-5381
Journal
FOREIGN
159
3
669
677
669
9
2010
2011
true
true
true
false
false
NONE
2024-02-15
false
35
0
35
32
0
35
34
35
32
35
35
32
32
32
3
0
35
32
35
32
0
2
2
D1
false
false
false
false
2012-01-13T10:19:55.000+0000
2013-02-23T19:18:00.000+0000
1
10
0
3
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
1512443
/api/authorship/1512443
1
0.33333334
true
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135682
true
PersonAuthorship
1512444
/api/authorship/1512444
2
0.33333334
false
false
Nenquin
M
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135681
true
PersonAuthorship
1512445
/api/authorship/1512445
3
0.333
false
true
true
Henquin
JC
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135680
true
PublicationIdentifier
366211
/api/publicationidentifier/366211
false
IDENTICAL
10.1111/j.1476-5381.2009.00588.x
https://doi.org/10.1111/j.1476-5381.2009.00588.x
false
210254
true
PublicationIdentifier
366209
/api/publicationidentifier/366209
false
IDENTICAL
000274407400016
https://www.webofscience.com/wos/woscc/full-record/000274407400016
false
210255
true
PublicationIdentifier
366210
/api/publicationidentifier/366210
false
IDENTICAL
76449109012
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-76449109012
false
954129
true
PublicationIdentifier
366212
/api/publicationidentifier/366212
false
IDENTICAL
20128805
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=20128805&dopt=Abstract
false
954130
true
Classification
12125
/api/classification/12125
true
true
SjrRating
5770388
/api/sjrrating/5770388
28
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
3004
/api/classificationexternal/3004
true
3004
true
D1
DIRECT
true
5770388
true
/api/publication/1504152
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Nenquin, M </span> <span class="author-type"> </span> ; <span class="author-name" > Henquin, JC ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504152" mtid="1504152" target="_blank">Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K plus channels</a></div> <div class="pub-info"> <span class="journal-title">BRITISH JOURNAL OF PHARMACOLOGY</span> <span class="journal-volume">159</span> : <span class="journal-issue">3</span> <span class="page"> pp. 669-677. , 9 p. </span> <span class="year">(2010)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1111/j.1476-5381.2009.00588.x" target="_blank" href="https://doi.org/10.1111/j.1476-5381.2009.00588.x"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000274407400016" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000274407400016"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="76449109012" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-76449109012"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="20128805" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=20128805&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:1504152 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 35</span> | Independent citation: 32 | Self citation: 3 | Unknown citation: 0 | Number of citations in WoS: 35 | Number of citations in Scopus: 32 | WoS/Scopus assigned: 35 | Number of citations with DOI: 34 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> ; <span class="author-name" >Nenquin M </span> ; <span class="author-name" >Henquin JC ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504152" target="_blank">Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K plus channels</a></div> <div> <span class="journal-title">BRITISH JOURNAL OF PHARMACOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0007-1188">0007-1188</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1476-5381">1476-5381</a>)</span>: <span class="journal-volume">159</span> <span class="journal-issue">3</span> <span class="page"> pp 669-677 </span> <span class="year">(2010)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1111/j.1476-5381.2009.00588.x" target="_blank" href="https://doi.org/10.1111/j.1476-5381.2009.00588.x"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000274407400016" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000274407400016"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="76449109012" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-76449109012"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="20128805" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=20128805&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 35</span> | Independent citation: 32 | Self citation: 3 | Unknown citation: 0 | Number of citations in WoS: 35 | Number of citations in Scopus: 32 | WoS/Scopus assigned: 35 | Number of citations with DOI: 34 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1504152&sort=publishedYear,desc&sort=title"> Number of cited publications: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 1504152</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 1504152</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Last Modified: 2018.10.09. 11:59 Admin Szuper (admin) </div> </div></div>
JournalArticle
1493077
VALIDATED
true
Department of Medical Biochemistry, Semmelweis University, Budapest H-1094, Hungary
Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 7HY, United Kingdom
Cited By :17
Export Date: 9 March 2022
CODEN: JGPLA
Correspondence Address: Csanády, L.; Department of Medical Biochemistry, , Budapest H-1094, Hungary; email: laszlo.csanady@eok.sote.hu
Chemicals/CAS: adenosine triphosphate, 15237-44-2, 56-65-5, 987-65-5; Adenosine Triphosphate, 56-65-5; Cystic Fibrosis Transmembrane Conductance Regulator, 126880-72-6
Funding details: Medical Research Council, MRC, G0501200
0
2014-11-18T16:17:37.000+0000
false
1493077
2024-02-15T19:56:06.181+0000
2021-05-14T08:42:03.149+0000
2011-04-04T12:14:43.000+0000
true
10015499
Csanády
László
/api/author/10015499
Author
true
10015499
2022-03-09T13:05:53.145+0000
2022-03-09T13:05:53.145+0000
2021-05-14T08:31:54.779+0000
true
10054198
xBökönyi
Zita
/api/admin/10054198
Admin
true
10054198
2021-05-14T08:42:03.163+0000
true
10054198
xBökönyi
Zita
/api/admin/10054198
Admin
true
10054198
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Szollosi, A
Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2
true
true
/api/journal/2517
REVIEWED
true
false
2517
false
2517
true
0022-1295
1540-7748
Journal
FOREIGN
136
4
407
423
407
17
2010
2011
true
true
true
false
true
false
NONE
2024-02-15
false
23
0
22
17
5
23
21
21
19
21
21
16
16
18
5
0
23
18
22
17
0
6
6
D1
false
10020191
false
false
false
2014-02-03T11:11:10.000+0000
2013-02-23T19:18:00.000+0000
Orvosi Biokémiai Intézet (SE / AOK / I)
2
12
1
3
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
1492345
/api/authorship/1492345
1
0.33333334
true
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12096235
true
PersonAuthorship
1492346
/api/authorship/1492346
2
0.33333334
false
false
Vergani
P
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12096234
true
PersonAuthorship
1492347
/api/authorship/1492347
3
0.333
false
true
true
Author
10015499
/api/author/10015499
Csanády
László
true
10015499
true
Csanády
L
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12096233
true
PublicationIdentifier
361316
/api/publicationidentifier/361316
false
IDENTICAL
10.1085/jgp.201010434
https://doi.org/10.1085/jgp.201010434
false
206800
true
PublicationIdentifier
361314
/api/publicationidentifier/361314
false
IDENTICAL
000284831500003
https://www.webofscience.com/wos/woscc/full-record/000284831500003
false
206801
true
PublicationIdentifier
361315
/api/publicationidentifier/361315
false
IDENTICAL
77957853858
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-77957853858
false
954125
true
PublicationIdentifier
361317
/api/publicationidentifier/361317
false
IDENTICAL
20876359
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=20876359&dopt=Abstract
false
954126
true
Classification
10619
/api/classification/10619
true
true
Classification
10610
/api/classification/10610
true
true
SjrRating
5741151
/api/sjrrating/5741151
10
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1314
/api/classificationexternal/1314
true
1314
true
D1
DIRECT
true
5741151
true
/api/publication/1493077
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Vergani, P </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10015499"> <a href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády, L ✉</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1493077" mtid="1493077" target="_blank">Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF GENERAL PHYSIOLOGY</span> <span class="journal-volume">136</span> : <span class="journal-issue">4</span> <span class="page"> pp. 407-423. , 17 p. </span> <span class="year">(2010)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1085/jgp.201010434" target="_blank" href="https://doi.org/10.1085/jgp.201010434"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000284831500003" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000284831500003"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="77957853858" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-77957853858"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="20876359" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=20876359&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:1493077 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 23</span> | Independent citation: 18 | Self citation: 5 | Unknown citation: 0 | Number of citations in WoS: 21 | Number of citations in Scopus: 19 | WoS/Scopus assigned: 21 | Number of citations with DOI: 21 </div> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" mtid="10020191"><a
href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A
(<span class="authorship-author-name">Szöllősi András</span>
<span class="authorAux-mtmt"> Biokémia</span>)
</a>
</span>
<span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry</span>
;
<span class="author-name" >Vergani P
</span>
;
<span class="author-name" mtid="10015499"><a
href="/gui2/?type=authors&mode=browse&sel=10015499" target="_blank">Csanády L ✉
(<span class="authorship-author-name">Csanády László</span>
<span class="authorAux-mtmt"> Biokémia</span>)
</a>
</span>
<span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Medical Biochemistry</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;1493077" target="_blank">Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2</a></div> <div> <span class="journal-title">JOURNAL OF GENERAL PHYSIOLOGY</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0022-1295">0022-1295</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1540-7748">1540-7748</a>)</span>:
<span class="journal-volume">136</span> <span class="journal-issue">4</span>
<span class="page">
pp 407-423
</span> <span class="year">(2010)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Language:
English
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="10.1085/jgp.201010434" target="_blank" href="https://doi.org/10.1085/jgp.201010434">
DOI
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="000284831500003" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000284831500003">
WoS
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="77957853858" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-77957853858">
Scopus
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="20876359" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=20876359&dopt=Abstract">
PubMed
</a>
</span>
</span>
<div class="publication-citation" style="margin-left: 0.5cm;">
<span title="" class="citingPub-count">Citing papers: 23</span>
| Independent citation: 18
| Self citation: 5
| Unknown citation: 0
| Number of citations in WoS: 21
| Number of citations in Scopus: 19
| WoS/Scopus assigned: 21
| Number of citations with DOI: 21
</div>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;1493077&sort=publishedYear,desc&sort=title">
Number of cited publications: 6
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Publication: 1493077</span>
| <span class="status-data status-VALIDATED"> Validated
</span>
<span class="oldId">Old id: 1493077</span> |
Core Citing
| <span class="type-subtype">Journal Article
( Article
)
</span>
| <span class="pub-category">Scientific</span>
| <span class="publication-sourceOfData">WOS</span>
</div>
<div class="lastModified">Last Modified: 2021.05.14. 10:42 Zita xBökönyi (INAKTÍV_SE_AOK_OBI_Admin5_BZ, admin)
</div>
<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Department of Medical Biochemistry, Semmelweis University, Budapest H-1094, Hungary
Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 7HY, United Kingdom
Cited By :17
Export Date: 9 March 2022
CODEN: JGPLA
Correspondence Address: C...</pre>
</div></div>
JournalArticle
1504153
VALIDATED
true
0
2014-10-16T16:25:41.000+0000
false
1504153
2024-02-15T20:24:10.186+0000
2022-05-17T12:40:52.121+0000
2011-04-20T10:42:28.000+0000
true
10020191
Szöllősi
András
/api/author/10020191
Author
true
10020191
2022-05-17T12:40:47.549+0000
2022-05-17T12:40:47.549+0000
2022-05-17T12:40:52.366+0000
true
10015544
Csajbók
Edit
/api/admin/10015544
Admin
true
10015544
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
1134514
Survey paper
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/1134514
Összefoglaló cikk
SubType
102
true
1134514
true
1
/api/category/1
Category
true
1
Henquin, JC
Shortcomings of current models of glucose-induced insulin secretion
true
true
/api/journal/28050
REVIEWED
true
false
28050
false
28050
true
1462-8902
1463-1326
Journal
FOREIGN
11
Suppl. 4
168
179
168
12
2009
2011
true
true
true
false
false
NONE
2024-02-15
false
69
0
69
61
0
68
69
63
62
69
69
61
61
61
8
0
69
61
69
61
0
3
3
Q1
false
false
false
false
2014-09-23T13:12:41.000+0000
2013-02-23T19:18:00.000+0000
1
10
0
4
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
1512446
/api/authorship/1512446
1
0.25
true
false
Henquin
JC
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135686
true
PersonAuthorship
1512447
/api/authorship/1512447
2
0.25
false
false
Nenquin
M
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135685
true
PersonAuthorship
1512448
/api/authorship/1512448
3
0.25
false
false
Ravier
MA
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135684
true
PersonAuthorship
1512449
/api/authorship/1512449
4
0.25
false
true
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135683
true
PublicationIdentifier
366215
/api/publicationidentifier/366215
false
IDENTICAL
10.1111/j.1463-1326.2009.01109.x
https://doi.org/10.1111/j.1463-1326.2009.01109.x
false
210256
true
PublicationIdentifier
366213
/api/publicationidentifier/366213
false
IDENTICAL
000270613000018
https://www.webofscience.com/wos/woscc/full-record/000270613000018
false
210257
true
PublicationIdentifier
366214
/api/publicationidentifier/366214
false
IDENTICAL
70350331458
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-70350331458
false
954303
true
PublicationIdentifier
366216
/api/publicationidentifier/366216
false
IDENTICAL
19817799
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=19817799&dopt=Abstract
false
954322
true
Classification
10545
/api/classification/10545
true
true
Classification
12215
/api/classification/12215
true
true
SjrRating
5786916
/api/sjrrating/5786916
22
0.24
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1310
/api/classificationexternal/1310
true
1310
true
Q1
DIRECT
true
5786916
true
/api/publication/1504153
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Henquin, JC </span> <span class="author-type"> </span> ; <span class="author-name" > Nenquin, M </span> <span class="author-type"> </span> ; <span class="author-name" > Ravier, MA </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504153" mtid="1504153" target="_blank">Shortcomings of current models of glucose-induced insulin secretion</a></div> <div class="pub-info"> <span class="journal-title">DIABETES OBESITY & METABOLISM</span> <span class="journal-volume">11</span> : <span class="journal-issue">Suppl. 4</span> <span class="page"> pp. 168-179. , 12 p. </span> <span class="year">(2009)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1111/j.1463-1326.2009.01109.x" target="_blank" href="https://doi.org/10.1111/j.1463-1326.2009.01109.x"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000270613000018" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000270613000018"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="70350331458" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-70350331458"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="19817799" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=19817799&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:1504153 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Survey paper ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 69</span> | Independent citation: 61 | Self citation: 8 | Unknown citation: 0 | Number of citations in WoS: 63 | Number of citations in Scopus: 62 | WoS/Scopus assigned: 69 | Number of citations with DOI: 69 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Henquin JC </span> ; <span class="author-name" >Nenquin M </span> ; <span class="author-name" >Ravier MA </span> ; <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504153" target="_blank">Shortcomings of current models of glucose-induced insulin secretion</a></div> <div> <span class="journal-title">DIABETES OBESITY & METABOLISM</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1462-8902">1462-8902</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1463-1326">1463-1326</a>)</span>: <span class="journal-volume">11</span> <span class="journal-issue">Suppl. 4</span> <span class="page"> pp 168-179 </span> <span class="year">(2009)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1111/j.1463-1326.2009.01109.x" target="_blank" href="https://doi.org/10.1111/j.1463-1326.2009.01109.x"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000270613000018" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000270613000018"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="70350331458" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-70350331458"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="19817799" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=19817799&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 69</span> | Independent citation: 61 | Self citation: 8 | Unknown citation: 0 | Number of citations in WoS: 63 | Number of citations in Scopus: 62 | WoS/Scopus assigned: 69 | Number of citations with DOI: 69 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1504153&sort=publishedYear,desc&sort=title"> Number of cited publications: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 1504153</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 1504153</span> | Core Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Last Modified: 2022.05.17. 14:40 Edit Csajbók (SE_KK_Admin5_CSE, admin) </div> </div></div>
JournalArticle
1504154
VALIDATED
true
0
2014-10-16T16:33:41.000+0000
false
1504154
2024-03-14T12:16:42.275+0000
2014-10-16T16:33:41.000+0000
2011-04-20T10:42:28.000+0000
true
10020191
Szöllősi
András
/api/author/10020191
Author
true
10020191
2018-10-20T15:48:59.514+0000
2018-10-20T15:48:59.514+0000
2012-01-13T10:20:02.000+0000
true
10019992
Zsárik
Judit
/api/admin/10019992
Admin
true
10019992
2014-09-23T13:21:17.000+0000
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Henquin, JC
Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2 beta
true
true
/api/journal/2443
REVIEWED
true
false
2443
false
2443
true
0022-0795
1479-6805
Journal
FOREIGN
196
3
573
581
573
9
2008
2011
true
true
true
false
false
NONE
2024-03-14
false
32
0
32
29
0
32
30
31
21
32
32
29
29
29
3
0
32
29
32
29
0
0
0
Q1
false
false
false
false
2012-01-13T10:20:02.000+0000
2013-02-23T19:18:00.000+0000
1
10
0
5
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
1512450
/api/authorship/1512450
1
0.2
true
false
Henquin
JC
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135694
true
PersonAuthorship
1512451
/api/authorship/1512451
2
0.2
false
false
Nenquin
M
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135693
true
PersonAuthorship
1512452
/api/authorship/1512452
3
0.2
false
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135692
true
PersonAuthorship
1512453
/api/authorship/1512453
4
0.2
false
false
Kubosaki
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135691
true
PersonAuthorship
1512454
/api/authorship/1512454
5
0.2
false
true
Notkins
AL
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135690
true
PublicationIdentifier
366219
/api/publicationidentifier/366219
false
IDENTICAL
10.1677/JOE-07-0496
https://doi.org/10.1677/JOE-07-0496
false
210258
true
PublicationIdentifier
366217
/api/publicationidentifier/366217
false
IDENTICAL
000254297800014
https://www.webofscience.com/wos/woscc/full-record/000254297800014
false
210259
true
PublicationIdentifier
366218
/api/publicationidentifier/366218
false
IDENTICAL
41149154844
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-41149154844
false
954384
true
PublicationIdentifier
366220
/api/publicationidentifier/366220
false
IDENTICAL
18310453
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=18310453&dopt=Abstract
false
954403
true
Classification
10545
/api/classification/10545
true
true
Classification
12215
/api/classification/12215
true
true
SjrRating
5831141
/api/sjrrating/5831141
22
0.24
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1310
/api/classificationexternal/1310
true
1310
true
Q1
DIRECT
true
5831141
true
/api/publication/1504154
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Henquin, JC </span> <span class="author-type"> </span> ; <span class="author-name" > Nenquin, M </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Kubosaki, A </span> <span class="author-type"> </span> ; <span class="author-name" > Notkins, AL </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504154" mtid="1504154" target="_blank">Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2 beta</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF ENDOCRINOLOGY</span> <span class="journal-volume">196</span> : <span class="journal-issue">3</span> <span class="page"> pp. 573-581. , 9 p. </span> <span class="year">(2008)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1677/JOE-07-0496" target="_blank" href="https://doi.org/10.1677/JOE-07-0496"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000254297800014" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000254297800014"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="41149154844" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-41149154844"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="18310453" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=18310453&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:1504154 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 32</span> | Independent citation: 29 | Self citation: 3 | Unknown citation: 0 | Number of citations in WoS: 31 | Number of citations in Scopus: 21 | WoS/Scopus assigned: 32 | Number of citations with DOI: 30 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" >Henquin JC </span> ; <span class="author-name" >Nenquin M </span> ; <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> ; <span class="author-name" >Kubosaki A </span> ; <span class="author-name" >Notkins AL </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504154" target="_blank">Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2 beta</a></div> <div> <span class="journal-title">JOURNAL OF ENDOCRINOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0022-0795">0022-0795</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1479-6805">1479-6805</a>)</span>: <span class="journal-volume">196</span> <span class="journal-issue">3</span> <span class="page"> pp 573-581 </span> <span class="year">(2008)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1677/JOE-07-0496" target="_blank" href="https://doi.org/10.1677/JOE-07-0496"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000254297800014" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000254297800014"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="41149154844" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-41149154844"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="18310453" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=18310453&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 32</span> | Independent citation: 29 | Self citation: 3 | Unknown citation: 0 | Number of citations in WoS: 31 | Number of citations in Scopus: 21 | WoS/Scopus assigned: 32 | Number of citations with DOI: 30 </div> <div class="mtid"><span class="long-pub-mtid">Publication: 1504154</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 1504154</span> | Core | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Last Modified: 2014.10.16. 18:33 Admin MTMT (admin) </div> </div></div>
JournalArticle
1504156
VALIDATED
true
0
2014-10-16T16:43:08.000+0000
false
1504156
2024-02-15T20:24:22.573+0000
2018-10-09T09:59:41.618+0000
2011-04-20T10:42:28.000+0000
true
10020191
Szöllősi
András
/api/author/10020191
Author
true
10020191
2018-10-09T09:59:41.618+0000
2018-10-09T10:21:30.561+0000
2012-01-13T10:20:10.000+0000
true
10019992
Zsárik
Judit
/api/admin/10019992
Admin
true
10019992
2014-09-23T13:31:20.000+0000
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Szollosi, A
Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels
true
true
/api/journal/2295
REVIEWED
true
false
2295
false
2295
true
0021-9258
1083-351X
Journal
FOREIGN
282
3
1747
1756
1747
10
2007
2011
true
true
true
false
false
NONE
2024-02-15
false
59
0
59
48
0
56
58
53
49
59
59
48
48
48
11
0
59
48
59
48
0
1
1
D1
false
false
false
false
2012-01-13T10:20:10.000+0000
2013-02-23T19:18:00.000+0000
1
10
0
5
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
1512458
/api/authorship/1512458
1
0.2
true
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135704
true
PersonAuthorship
1512459
/api/authorship/1512459
2
0.2
false
false
Nenquin
M
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135703
true
PersonAuthorship
1512460
/api/authorship/1512460
3
0.2
false
false
Aguilar-Bryan
L
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135702
true
PersonAuthorship
1512461
/api/authorship/1512461
4
0.2
false
false
Bryan
J
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135701
true
PersonAuthorship
1512462
/api/authorship/1512462
5
0.2
false
true
Henquin
JC
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135700
true
PublicationIdentifier
366227
/api/publicationidentifier/366227
false
IDENTICAL
10.1074/jbc.M609875200
https://doi.org/10.1074/jbc.M609875200
false
210262
true
PublicationIdentifier
366225
/api/publicationidentifier/366225
false
IDENTICAL
000243451300026
https://www.webofscience.com/wos/woscc/full-record/000243451300026
false
210263
true
PublicationIdentifier
366226
/api/publicationidentifier/366226
false
IDENTICAL
33847268722
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-33847268722
false
954409
true
PublicationIdentifier
366228
/api/publicationidentifier/366228
false
IDENTICAL
17138557
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17138557&dopt=Abstract
false
954411
true
Classification
10545
/api/classification/10545
true
true
SjrRating
5871933
/api/sjrrating/5871933
12
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1303
/api/classificationexternal/1303
true
1303
true
D1
DIRECT
true
5871933
true
/api/publication/1504156
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Nenquin, M </span> <span class="author-type"> </span> ; <span class="author-name" > Aguilar-Bryan, L </span> <span class="author-type"> </span> ; <span class="author-name" > Bryan, J </span> <span class="author-type"> </span> ; <span class="author-name" > Henquin, JC </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504156" mtid="1504156" target="_blank">Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF BIOLOGICAL CHEMISTRY</span> <span class="journal-volume">282</span> : <span class="journal-issue">3</span> <span class="page"> pp. 1747-1756. , 10 p. </span> <span class="year">(2007)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1074/jbc.M609875200" target="_blank" href="https://doi.org/10.1074/jbc.M609875200"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000243451300026" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000243451300026"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="33847268722" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-33847268722"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="17138557" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17138557&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:1504156 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 59</span> | Independent citation: 48 | Self citation: 11 | Unknown citation: 0 | Number of citations in WoS: 53 | Number of citations in Scopus: 49 | WoS/Scopus assigned: 59 | Number of citations with DOI: 58 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> ; <span class="author-name" >Nenquin M </span> ; <span class="author-name" >Aguilar-Bryan L </span> ; <span class="author-name" >Bryan J </span> ; <span class="author-name" >Henquin JC </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504156" target="_blank">Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels</a></div> <div> <span class="journal-title">JOURNAL OF BIOLOGICAL CHEMISTRY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0021-9258">0021-9258</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1083-351X">1083-351X</a>)</span>: <span class="journal-volume">282</span> <span class="journal-issue">3</span> <span class="page"> pp 1747-1756 </span> <span class="year">(2007)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1074/jbc.M609875200" target="_blank" href="https://doi.org/10.1074/jbc.M609875200"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000243451300026" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000243451300026"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="33847268722" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-33847268722"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="17138557" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17138557&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 59</span> | Independent citation: 48 | Self citation: 11 | Unknown citation: 0 | Number of citations in WoS: 53 | Number of citations in Scopus: 49 | WoS/Scopus assigned: 59 | Number of citations with DOI: 58 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1504156&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 1504156</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 1504156</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Last Modified: 2018.10.09. 11:59 Admin Szuper (admin) </div> </div></div>
JournalArticle
1504155
VALIDATED
true
0
2014-10-16T16:43:08.000+0000
false
1504155
2024-02-15T20:23:56.086+0000
2018-10-09T09:59:41.618+0000
2011-04-20T10:42:28.000+0000
true
10020191
Szöllősi
András
/api/author/10020191
Author
true
10020191
2018-10-09T09:59:41.618+0000
2018-10-09T10:21:30.283+0000
2012-01-13T10:20:07.000+0000
true
10019992
Zsárik
Judit
/api/admin/10019992
Admin
true
10019992
2014-09-23T13:27:52.000+0000
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Szollosi, A
Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal
true
true
/api/journal/2295
REVIEWED
true
false
2295
false
2295
true
0021-9258
1083-351X
Journal
FOREIGN
282
20
14768
14776
14768
9
2007
2011
true
true
true
false
false
NONE
2024-02-15
false
29
0
29
25
0
29
29
28
17
29
29
25
25
25
4
0
29
25
29
25
0
2
2
D1
false
false
false
false
2012-01-13T10:20:07.000+0000
2013-02-23T19:18:00.000+0000
1
10
0
3
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
1512455
/api/authorship/1512455
1
0.33333334
true
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135699
true
PersonAuthorship
1512456
/api/authorship/1512456
2
0.33333334
false
false
Nenquin
M
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135698
true
PersonAuthorship
1512457
/api/authorship/1512457
3
0.33333334
false
true
Henquin
JC
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135697
true
PublicationIdentifier
366223
/api/publicationidentifier/366223
false
IDENTICAL
10.1074/jbc.M701382200
https://doi.org/10.1074/jbc.M701382200
false
210260
true
PublicationIdentifier
366221
/api/publicationidentifier/366221
false
IDENTICAL
000246589000012
https://www.webofscience.com/wos/woscc/full-record/000246589000012
false
210261
true
PublicationIdentifier
366222
/api/publicationidentifier/366222
false
IDENTICAL
34447527887
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-34447527887
false
954394
true
PublicationIdentifier
366224
/api/publicationidentifier/366224
false
IDENTICAL
17389589
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17389589&dopt=Abstract
false
954396
true
Classification
10545
/api/classification/10545
true
true
SjrRating
5871933
/api/sjrrating/5871933
12
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1303
/api/classificationexternal/1303
true
1303
true
D1
DIRECT
true
5871933
true
/api/publication/1504155
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Nenquin, M </span> <span class="author-type"> </span> ; <span class="author-name" > Henquin, JC </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504155" mtid="1504155" target="_blank">Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF BIOLOGICAL CHEMISTRY</span> <span class="journal-volume">282</span> : <span class="journal-issue">20</span> <span class="page"> pp. 14768-14776. , 9 p. </span> <span class="year">(2007)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1074/jbc.M701382200" target="_blank" href="https://doi.org/10.1074/jbc.M701382200"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000246589000012" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000246589000012"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="34447527887" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-34447527887"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="17389589" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17389589&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:1504155 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core Citing </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 29</span> | Independent citation: 25 | Self citation: 4 | Unknown citation: 0 | Number of citations in WoS: 28 | Number of citations in Scopus: 17 | WoS/Scopus assigned: 29 | Number of citations with DOI: 29 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10020191"><a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A (<span class="authorship-author-name">Szöllősi András</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> ; <span class="author-name" >Nenquin M </span> ; <span class="author-name" >Henquin JC </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504155" target="_blank">Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal</a></div> <div> <span class="journal-title">JOURNAL OF BIOLOGICAL CHEMISTRY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0021-9258">0021-9258</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1083-351X">1083-351X</a>)</span>: <span class="journal-volume">282</span> <span class="journal-issue">20</span> <span class="page"> pp 14768-14776 </span> <span class="year">(2007)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1074/jbc.M701382200" target="_blank" href="https://doi.org/10.1074/jbc.M701382200"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000246589000012" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000246589000012"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="34447527887" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-34447527887"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="17389589" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17389589&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 29</span> | Independent citation: 25 | Self citation: 4 | Unknown citation: 0 | Number of citations in WoS: 28 | Number of citations in Scopus: 17 | WoS/Scopus assigned: 29 | Number of citations with DOI: 29 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1504155&sort=publishedYear,desc&sort=title"> Number of cited publications: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 1504155</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 1504155</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Last Modified: 2018.10.09. 11:59 Admin Szuper (admin) </div> </div></div>
JournalArticle
1504157
VALIDATED
true
Nenquin M and Szollosi A contributed equally to this work.
0
2014-09-23T13:53:37.000+0000
false
1504157
2024-02-15T20:23:59.533+0000
2014-09-23T13:53:37.000+0000
2011-04-20T10:42:29.000+0000
true
10020191
Szöllősi
András
/api/author/10020191
Author
true
10020191
2018-10-20T15:37:00.272+0000
2018-10-20T15:37:00.272+0000
2014-09-23T13:53:37.000+0000
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
2014-09-23T13:53:37.000+0000
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
true
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Nenquin, M
Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells
true
true
/api/journal/2295
REVIEWED
true
false
2295
false
2295
true
0021-9258
1083-351X
Journal
FOREIGN
279
31
32316
32324
32316
9
2004
2011
true
true
true
false
false
NONE
2024-02-15
false
true
10026589
Tichy
Rita
/api/admin/10026589
Admin
true
10026589
92
0
92
68
0
89
92
86
49
92
92
68
68
68
24
0
92
68
92
68
0
0
0
D1
false
false
false
false
2014-09-23T13:53:37.000+0000
2013-02-23T19:18:00.000+0000
1
10
0
5
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
1512463
/api/authorship/1512463
1
0.2
true
false
Nenquin
M
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135711
true
PersonAuthorship
1512464
/api/authorship/1512464
2
0.2
false
false
Author
10020191
/api/author/10020191
Szöllősi
András
true
10020191
true
Szollosi
A
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135710
true
PersonAuthorship
1512465
/api/authorship/1512465
3
0.2
false
false
Aguilar-Bryan
L
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135709
true
PersonAuthorship
1512466
/api/authorship/1512466
4
0.2
false
false
Bryan
J
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135708
true
PersonAuthorship
1512467
/api/authorship/1512467
5
0.2
false
true
Henquin
JC
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
12135707
true
PublicationIdentifier
366231
/api/publicationidentifier/366231
false
IDENTICAL
10.1074/jbc.M402076200
https://doi.org/10.1074/jbc.M402076200
false
210264
true
PublicationIdentifier
366229
/api/publicationidentifier/366229
false
IDENTICAL
000222849700042
https://www.webofscience.com/wos/woscc/full-record/000222849700042
false
210265
true
PublicationIdentifier
366230
/api/publicationidentifier/366230
false
IDENTICAL
3542993224
http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-3542993224
false
954414
true
PublicationIdentifier
366232
/api/publicationidentifier/366232
false
IDENTICAL
15175349
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15175349&dopt=Abstract
false
954415
true
Classification
10545
/api/classification/10545
true
true
SjrRating
5988745
/api/sjrrating/5988745
8
0.1
journal
RatingType
10002
/api/ratingtype/10002
sjr
true
true
ClassificationExternal
1303
/api/classificationexternal/1303
true
1303
true
D1
DIRECT
true
5988745
true
/api/publication/1504157
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Nenquin, M </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10020191"> <a href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Aguilar-Bryan, L </span> <span class="author-type"> </span> ; <span class="author-name" > Bryan, J </span> <span class="author-type"> </span> ; <span class="author-name" > Henquin, JC </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504157" mtid="1504157" target="_blank">Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF BIOLOGICAL CHEMISTRY</span> <span class="journal-volume">279</span> : <span class="journal-issue">31</span> <span class="page"> pp. 32316-32324. , 9 p. </span> <span class="year">(2004)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1074/jbc.M402076200" target="_blank" href="https://doi.org/10.1074/jbc.M402076200"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000222849700042" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000222849700042"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="3542993224" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-3542993224"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="15175349" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15175349&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Publication:1504157 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Validated </span></span> <span class="pub-core">Core </span> <span class="pub-type">Journal Article (Article ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Scientific</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 92</span> | Independent citation: 68 | Self citation: 24 | Unknown citation: 0 | Number of citations in WoS: 86 | Number of citations in Scopus: 49 | WoS/Scopus assigned: 92 | Number of citations with DOI: 92 </div> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png">
<div class="autype autype0"> <span class="author-name" >Nenquin M
</span>
;
<span class="author-name" mtid="10020191"><a
href="/gui2/?type=authors&mode=browse&sel=10020191" target="_blank">Szollosi A
(<span class="authorship-author-name">Szöllősi András</span>
<span class="authorAux-mtmt"> Biokémia</span>)
</a>
</span>
;
<span class="author-name" >Aguilar-Bryan L
</span>
;
<span class="author-name" >Bryan J
</span>
;
<span class="author-name" >Henquin JC
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;1504157" target="_blank">Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells</a></div> <div> <span class="journal-title">JOURNAL OF BIOLOGICAL CHEMISTRY</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0021-9258">0021-9258</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1083-351X">1083-351X</a>)</span>:
<span class="journal-volume">279</span> <span class="journal-issue">31</span>
<span class="page">
pp 32316-32324
</span> <span class="year">(2004)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Language:
English
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="10.1074/jbc.M402076200" target="_blank" href="https://doi.org/10.1074/jbc.M402076200">
DOI
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="000222849700042" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000222849700042">
WoS
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="3542993224" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-3542993224">
Scopus
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="15175349" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15175349&dopt=Abstract">
PubMed
</a>
</span>
</span>
<div class="publication-citation" style="margin-left: 0.5cm;">
<span title="" class="citingPub-count">Citing papers: 92</span>
| Independent citation: 68
| Self citation: 24
| Unknown citation: 0
| Number of citations in WoS: 86
| Number of citations in Scopus: 49
| WoS/Scopus assigned: 92
| Number of citations with DOI: 92
</div>
<div class="mtid"><span class="long-pub-mtid">Publication: 1504157</span>
| <span class="status-data status-VALIDATED"> Validated
</span>
<span class="oldId">Old id: 1504157</span> |
Core
| <span class="type-subtype">Journal Article
( Article
)
</span>
| <span class="pub-category">Scientific</span>
| <span class="publication-sourceOfData">WOS</span>
</div>
<div class="lastModified">Last Modified: 2014.09.23. 15:53 Rita Tichy (SE_KK_Admin5_TR, admin)
</div>
<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Nenquin M and Szollosi A contributed equally to this work.</pre>
</div></div>