TY - JOUR AU - Raska, Alexandra AU - Balog Virág, Kata AU - Egri, Barnabás AU - Csikós, Petra (Metta) AU - Beinrohr, László AU - Szabó, László AU - Tenekedjiev, Kiril AU - Nikolova, Natalia AU - Longstaff, Colin AU - Roberts, Ian AU - Kolev, Kraszimir Nikolaev AU - Wohner, Nikolett TI - Synergism of red blood cells and tranexamic acid in the inhibition of fibrinolysis JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 22 PY - 2024 IS - 3 SP - 794 EP - 804 PG - 11 SN - 1538-7933 DO - 10.1016/j.jtha.2023.11.009 UR - https://m2.mtmt.hu/api/publication/34403493 ID - 34403493 N1 - Alexandra Raska and Kata Kalman contributed equally to this work and share the first authorship. Krasimir Kolev and Nikolett Wohner contributed equally to this work and share the senior authorship. LA - English DB - MTMT ER - TY - JOUR AU - Komorowicz, Erzsébet AU - Farkas, Veronika Judit AU - Szabó, László AU - Cherrington, Sophie AU - Thelwell, Craig AU - Kolev, Kraszimir Nikolaev TI - DNA and histones impair the mechanical stability and lytic susceptibility of fibrin formed by staphylocoagulase JF - FRONTIERS IN IMMUNOLOGY J2 - FRONT IMMUNOL VL - 14 PY - 2023 PG - 12 SN - 1664-3224 DO - 10.3389/fimmu.2023.1233128 UR - https://m2.mtmt.hu/api/publication/34103923 ID - 34103923 LA - English DB - MTMT ER - TY - JOUR AU - Lovas, Miklós AU - Tanka-Salamon, Anna AU - Beinrohr, László AU - Voszka, István AU - Szabó, László AU - Molnár, Kinga AU - Kolev, Kraszimir Nikolaev TI - Polyphosphate nanoparticles enhance the fibrin stabilization by histones more efficiently than linear polyphosphates JF - PLOS ONE J2 - PLOS ONE VL - 17 PY - 2022 IS - 4 PG - 18 SN - 1932-6203 DO - 10.1371/journal.pone.0266782 UR - https://m2.mtmt.hu/api/publication/32793507 ID - 32793507 LA - English DB - MTMT ER - TY - JOUR AU - Maróthyné Tóth, Erzsébet AU - Beinrohr, László AU - Gubucz, István AU - Szabó, László AU - Tenekedjiev, Kiril AU - Nikolova, Natalia AU - Nagy, Anikó Ilona AU - Hidi, László AU - Sótonyi, Péter AU - Szikora, István AU - Merkely, Béla Péter AU - Kolev, Kraszimir Nikolaev TI - Fibrin to von Willebrand factor ratio in arterial thrombi is associated with plasma levels of inflammatory biomarkers and local abundance of extracellular DNA JF - THROMBOSIS RESEARCH J2 - THROMB RES VL - 209 PY - 2022 SP - 8 EP - 15 PG - 8 SN - 0049-3848 DO - 10.1016/j.thromres.2021.11.011 UR - https://m2.mtmt.hu/api/publication/32498590 ID - 32498590 N1 - Department of Biochemistry, Semmelweis University, Budapest, Hungary National Institute of Clinical Neurosciences, Budapest, Hungary Department of Functional and Structural Materials, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary Australian Maritime College, University of Tasmania, Launceston, Australia Department of Information Technology, Nikola Vaptsarov Naval Academy, Varna, Bulgaria Heart and Vascular Center, Semmelweis University, Budapest, Hungary Department of Medicine, Karolinska Institute, Stockholm, Sweden Cited By :2 Export Date: 14 November 2022 CODEN: THBRA Correspondence Address: Kolev, K.; Semmelweis University, 1094 Budapest, Hungary; email: Krasimir.Kolev@eok.sote.hu LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Maróthyné Tóth, Erzsébet AU - Farkas, Ádám Zoltán AU - Farkas, Veronika Judit AU - Komorowicz, Erzsébet AU - Feller, Tímea AU - Kiss, Balázs AU - Kellermayer, Miklós AU - Szabó, László AU - Wacha, András Ferenc AU - Bóta, Attila AU - Longstaff, Colin AU - Kolev, Kraszimir Nikolaev TI - Citrullinated fibrinogen forms densely packed clots with decreased permeability JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 20 PY - 2022 IS - 12 SP - 2862 EP - 2872 PG - 11 SN - 1538-7933 DO - 10.1111/jth.15875 UR - https://m2.mtmt.hu/api/publication/33088371 ID - 33088371 LA - English DB - MTMT ER - TY - JOUR AU - Hidi, László AU - Komorowicz, Erzsébet AU - Kovács, Gergely Imre AU - Szeberin, Zoltán AU - Garbaisz, Dávid AU - Nikolova, Natalia AU - Tenekedjiev, Kiril AU - Szabó, László AU - Kolev, Kraszimir Nikolaev AU - Sótonyi, Péter TI - Cryopreservation moderates the thrombogenicity of arterial allografts during storage JF - PLOS ONE J2 - PLOS ONE VL - 16 PY - 2021 IS - 7 PG - 16 SN - 1932-6203 DO - 10.1371/journal.pone.0255114 UR - https://m2.mtmt.hu/api/publication/32111136 ID - 32111136 N1 - Department of Vascular and Endovascular Surgery, Heart and Vascular Center, Semmelweis University, Budapest, Hungary Department of Biochemistry, Semmelweis University, Budapest, Hungary Department of Information Technology, Nikola Vaptsarov Naval Academy, Varna, Bulgaria Australian Maritime College, University of Tasmania, Launceston, Australia Department of Functional and Structural Materials, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary Cited By :1 Export Date: 13 May 2022 CODEN: POLNC Correspondence Address: Hidi, L.; Department of Vascular and Endovascular Surgery, Hungary; email: drhidilaszlo@gmail.com Chemicals/CAS: fibrin, 9001-31-4; fibrinogen, 9001-32-5; Fibrin LA - English DB - MTMT ER - TY - JOUR AU - Komorowicz, Erzsébet AU - Balázs, Nóra AU - Tanka-Salamon, Anna AU - Varga, Zoltán AU - Szabó, László AU - Bóta, Attila AU - Longstaff, Colin AU - Kolev, Kraszimir Nikolaev TI - Size- and charge-dependent modulation of the lytic susceptibility and mechanical stability of fibrin-histone clots by heparin and polyphosphate variants JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 19 PY - 2021 SP - 1307 EP - 1318 PG - 12 SN - 1538-7933 DO - 10.1111/jth.15258 UR - https://m2.mtmt.hu/api/publication/31884048 ID - 31884048 AB - Neutrophil extracellular traps (NETs) containing DNA and histones are expelled from neutrophils in infection and thrombosis. Heparins, anticoagulant polyanions, can neutralize histones with a potential therapeutic advantage in sepsis. Polyphosphates, procoagulant polyanions, are released by platelets and microorganisms.To characterize the combined effects of NET components and polyanions on clot structure, mechanical properties and lytic susceptibility.Scanning electron microscopy, pressure-driven permeation, turbidimetry, and oscillation rheometry were used for the characterization of the structure, viscoelasticity, and kinetics of formation and lysis of fibrin and plasma clots containing histones+/-DNA in combination with unfractionated heparin, its desulfated derivatives, low molecular weight heparin (LMWH), pentasaccharide, and polyphosphates of different sizes.Histones and DNA inhibited fibrin lysis by plasmin, but this behavior was not neutralized by negatively charged heparins or short polyphosphates. Rather, fibrin lysis was further inhibited by added polyanions. Histones inhibited plasma clot lysis by tissue plasminogen activator and the response to added heparin was size dependent. Unfractionated heparin, LMWH, and pentasaccharide had no effect, exacerbated, or reversed histone inhibition, respectively. Histones increased the mechanical strength of fibrin, which was exacerbated by smaller heparin and polyphosphate molecules. Histones increased fibrin diameter and pore size of fibrin clots and this effect was neutralized by all heparin variants but enhanced by polyphosphates.Despite their common polyanionic character, heparins and polyphosphates exert distinct effects on fibrin mechanical and fibrinolytic stability. Anti-fibrinolytic effects of histones were more often enhanced by polyanions not counteracted. Careful selection of anti-histone strategies is required if they are to be combined with thrombolytic therapy. LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Sorvillo, Nicoletta AU - Cherpokova, Deya AU - Farkas, Ádám Zoltán AU - Farkas, Veronika Judit AU - Komorowicz, Erzsébet AU - Feller, Tímea AU - Kiss, Balázs AU - Kellermayer, Miklós AU - Szabó, László AU - Wacha, András Ferenc AU - Bóta, Attila AU - Longstaff, Colin AU - Wagner, Denisa D AU - Kolev, Kraszimir Nikolaev TI - Citrullinated Fibrinogen Renders Clots Mechanically Less Stable, but Lysis-Resistant JF - CIRCULATION RESEARCH J2 - CIRC RES VL - 129 PY - 2021 IS - 2 SP - 342 EP - 344 PG - 3 SN - 0009-7330 DO - 10.1161/CIRCRESAHA.121.319061 UR - https://m2.mtmt.hu/api/publication/32036728 ID - 32036728 LA - English DB - MTMT ER - TY - JOUR AU - Komorowicz, Erzsébet AU - Balázs, Nóra AU - Tanka-Salamon, Anna AU - Varga, Zoltán AU - Szabó, László AU - Bóta, Attila AU - Longstaff, Colin AU - Kolev, Kraszimir Nikolaev TI - Biorelevant polyanions stabilize fibrin against mechanical and proteolytic decomposition: Effects of polymer size and electric charge JF - JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS J2 - J MECH BEHAV BIOMED VL - 102 PY - 2020 SN - 1751-6161 DO - 10.1016/j.jmbbm.2019.103459 UR - https://m2.mtmt.hu/api/publication/30837033 ID - 30837033 LA - English DB - MTMT ER - TY - JOUR AU - Lovas, M AU - Tanka-Salamon, A AU - Szabó, László AU - Kolev, Kraszimir Nikolaev TI - Polyphosphate Nanoparticles Are More Potent Stabilizers of Fibrin than Linear Polyphosphates and Histones Enhance their Effect JF - RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS J2 - Res Pract Thromb Haemost VL - 4 PY - 2020 IS - S1 SP - 364 EP - 365 PG - 2 SN - 2475-0379 DO - 10.1002/rth2.12393 UR - https://m2.mtmt.hu/api/publication/31402111 ID - 31402111 LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Sorvillo, N AU - Cherpokova, D AU - Farkas, Veronika Judit AU - Farkas, Ádám Zoltán AU - Komorowicz, Erzsébet AU - Feller, Tímea AU - Kiss, Balázs AU - Kellermayer, Miklós AU - Szabó, László AU - Wacha, András Ferenc AU - Bóta, Attila AU - Longstaff, C AU - Wagner, D AU - Kolev, Kraszimir Nikolaev TI - Fibrinogen Is Citrullinated in Venous Thrombi and Forms Fragile Clots with Increased Resistance to Lysis JF - RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS J2 - Res Pract Thromb Haemost VL - 4 PY - 2020 IS - S1 SP - 5 EP - 6 PG - 2 SN - 2475-0379 DO - 10.1002/rth2.12401 UR - https://m2.mtmt.hu/api/publication/31402116 ID - 31402116 LA - English DB - MTMT ER - TY - JOUR AU - Farkas, Ádám Zoltán AU - Farkas, Veronika Judit AU - Szabó, László AU - Wacha, András Ferenc AU - Bóta, Attila AU - Csehi, Lóránt AU - Kolev, Kraszimir Nikolaev AU - Thelwell, Craig TI - Structure, Mechanical, and Lytic Stability of Fibrin and Plasma Coagulum Generated by Staphylocoagulase From Staphylococcus aureus JF - FRONTIERS IN IMMUNOLOGY J2 - FRONT IMMUNOL VL - 10 PY - 2019 PG - 11 SN - 1664-3224 DO - 10.3389/fimmu.2019.02967 UR - https://m2.mtmt.hu/api/publication/31017737 ID - 31017737 LA - English DB - MTMT ER - TY - JOUR AU - Farkas, Ádám Zoltán AU - Farkas, Veronika Judit AU - Gubucz, István AU - Szabó, László AU - Bálint, Krisztián AU - Tenekedjiev, Kiril AU - Nagy, Anikó Ilona AU - Sótonyi, Péter AU - Hidi, László AU - Nagy, Zoltán AU - Szikora, István AU - Merkely, Béla Péter AU - Kolev, Kraszimir Nikolaev TI - Neutrophil extracellular traps in thrombi retrieved during interventional treatment of ischemic arterial diseases JF - THROMBOSIS RESEARCH J2 - THROMB RES VL - 175 PY - 2019 SP - 46 EP - 52 PG - 7 SN - 0049-3848 DO - 10.1016/j.thromres.2019.01.006 UR - https://m2.mtmt.hu/api/publication/30393047 ID - 30393047 N1 - Farkas Ádám Z. and Farkas Veronika J. contributed equally to this study. LA - English DB - MTMT ER - TY - JOUR AU - Farkas, Ádám Zoltán AU - Farkas, Veronika Judit AU - Szabó, László AU - Csehi, LM AU - Kolev, Kraszimir Nikolaev AU - Thelwell, C TI - Structure, Mechanical and Lytic Stability of Fibrin and Plasma Coagulum Generated by Staphylocoagulase from Staphylococcus aureus JF - RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS J2 - Res Pract Thromb Haemost VL - 3 PY - 2019 IS - Suppl.1 SP - 457 SN - 2475-0379 UR - https://m2.mtmt.hu/api/publication/30719802 ID - 30719802 LA - English DB - MTMT ER - TY - JOUR AU - Kolev, Kraszimir Nikolaev AU - Longstaff, C AU - Balázs, N AU - Tanka-Salamon, A AU - Varga, Zoltán AU - Szabó, László AU - Bóta, Attila AU - Komorowicz, E TI - Biorelevant Polyanions Modulate the Structure and Stability of Fibrin in a Size- , and Charge- dependent Manner. JF - RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS J2 - Res Pract Thromb Haemost VL - 3 PY - 2019 IS - Suppl.1 SP - 217 SN - 2475-0379 DO - 10.1002/rth2.12229 UR - https://m2.mtmt.hu/api/publication/30719799 ID - 30719799 LA - English DB - MTMT ER - TY - JOUR AU - Csehi, LM AU - Farkas, Ádám Zoltán AU - Farkas, Veronika Judit AU - Szabó, László AU - Thelwell, C AU - Kolev, Kraszimir Nikolaev TI - A stafilokoaguláz megváltoztatja a fibrinszerkezetet és csökkenti mechanikai stabilitását JF - METABOLIZMUS J2 - METABOLIZMUS VL - 16 PY - 2018 IS - Suppl.1 SP - I13 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/30371246 ID - 30371246 N1 - Ellenőrizve autopszia alapján. (2020-07-23, KZ) LA - Hungarian DB - MTMT ER - TY - JOUR AU - Gellért, Ákos AU - Pósa, Tímea AU - Fábián, Attila László AU - Szabó, László AU - Bóka, Károly AU - Forró, Barbara AU - Salánki, Katalin AU - Drahos, László AU - Tóth, Eszter AU - Juhász, Angéla AU - Balázs, Ervin TI - A single point mutation on the cucumber mosaic virus surface induces an unexpected and strong interaction with the F1 complex of the ATP synthase in Nicotiana clevelandii plants JF - VIRUS RESEARCH J2 - VIRUS RES VL - 251 PY - 2018 SP - 47 EP - 55 PG - 9 SN - 0168-1702 DO - 10.1016/j.virusres.2018.05.005 UR - https://m2.mtmt.hu/api/publication/3372094 ID - 3372094 AB - A previous study showed that a single amino acid difference in the cucumber mosaic virus (CMV) capsid protein (CP) elicits unusual symptoms. The wild-type strain (CMV-R) induces green mosaic symptoms and malformation while the mutant strain (CMV-R3E79R) causes chlorotic lesions on inoculated leaves and strong stunting with necrosis on systemic leaves. Virion preparations of CMV-R and CMV-R3E79R were partially purified from Nicotiana clevelandii A. Gray and analysed by two-dimensional gel electrophoresis. Their separated protein patterns showed remarkable differences at the 50–75 kDa range, both in numbers and intensity of spots, with more protein spots for the mutant CMV. Mass spectrometry analysis demonstrated that the virion preparations contained host proteins identified as ATP synthase alpha and beta subunits as well as small and large Rubisco subunits, respectively. Virus overlay protein binding assay (VOPBA), immunogold electron microscopy and modified ELISA experiments were used to prove the direct interaction between the virus particle and the N. clevelandii ATP synthase F1 motor complex. Protein-protein docking study revealed that the electrostatic change in the mutant CMV can introduce stronger interactions with ATP synthase F1 complex. Based on our findings we suggest that the mutation present in the CP can have a direct effect on the long–distance movement and systemic symptoms. In molecular view the mutant CMV virion can lethally block the rotation of the ATP synthase F1 motor complex which may lead to cell apoptosis, and finally to plant death. LA - English DB - MTMT ER - TY - JOUR AU - Komorowicz, E AU - Tanka-Salamon, A AU - Varga, Zoltán AU - Szabó, László AU - Bóta, Attila AU - Kolev, K TI - Polifoszfátok a fibrin szerkezetére gyakorolt mechanikai és litikus stabilizáló hatása a foszfátpolimer-méret és a Hiszton/DNS-jelenlét függvényében JF - METABOLIZMUS J2 - METABOLIZMUS VL - 16 PY - 2018 SP - 1 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/31134817 ID - 31134817 LA - Hungarian DB - MTMT ER - TY - CONF AU - Pankaczi, F AU - Farkas, Z AU - Halasy, V AU - Larsson, S AU - Pólya, S AU - Lantos, Brigitta AU - Kovács, K AU - Klencsár, Zoltán AU - May, Zoltán AU - Sándor, Z AU - Szabó, GE AU - Bódis, Eszter AU - Szabó, László AU - Kuzmann, E AU - Homonnay, Z AU - Tolnai, Gyula AU - Solti, Ádám AU - Fodor, F ED - Schmidt, Wolfgang TI - Manufactured nanomaterials: new iron based fertilizers or potentially toxic agents? T2 - 19th International Symposium on Iron Nutrition and Interactions in Plants PB - Academia Sinica PY - 2018 SP - 35 UR - https://m2.mtmt.hu/api/publication/3415276 ID - 3415276 LA - English DB - MTMT ER - TY - JOUR AU - Tanka‐Salamon, A AU - Lovas, M AU - Voszka, I AU - Szabó, László AU - Kolev, Kraszimir Nikolaev TI - Polyphoshate Nanoparticles Slow Down the Clotting of Fibrinogen and Increase the Lytic Stability of Fibrin JF - RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS J2 - Res Pract Thromb Haemost VL - 2 PY - 2018 IS - Suppl. 1 SP - 143 EP - 4 SN - 2475-0379 DO - 10.1002/rth2.12125 UR - https://m2.mtmt.hu/api/publication/3397836 ID - 3397836 LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Farkas, Veronika Judit AU - Kőhidai, László AU - Szabó, László AU - Farkas, Ádám Zoltán AU - Polgár, Lívia AU - Chinopoulos, Christos AU - Kolev, Kraszimir Nikolaev TI - Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 8 PY - 2018 IS - 1 PG - 13 SN - 2045-2322 DO - 10.1038/s41598-018-23725-4 UR - https://m2.mtmt.hu/api/publication/3350339 ID - 3350339 LA - English DB - MTMT ER - TY - JOUR AU - Beck, MT AU - Bertóti, Imre AU - Mohai, Miklós AU - Németh, Péter AU - Pekkerné Jakab, Emma AU - Szabó, László AU - Szépvölgyi, János TI - Gold nano-particle formation from crystalline AuCN: Comparison of thermal, plasma- and ion-activated decomposition JF - JOURNAL OF SOLID STATE CHEMISTRY J2 - J SOLID STATE CHEM VL - 246 PY - 2017 SP - 65 EP - 74 PG - 10 SN - 0022-4596 DO - 10.1016/j.jssc.2016.10.031 UR - https://m2.mtmt.hu/api/publication/3162797 ID - 3162797 LA - English DB - MTMT ER - TY - JOUR AU - Farkas, Veronika Judit AU - Kőhidai, László AU - Szabó, László AU - Chinopoulos, Christos AU - Polgár, Lívia AU - Kolev, Kraszimir Nikolaev AU - Varjú, Imre TI - Cyclophilin D Restricts the Lytic Susceptibility of Fibrin via Modulation of Platelet Functions JF - RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS J2 - Res Pract Thromb Haemost VL - 1 PY - 2017 IS - Suppl 1 SN - 2475-0379 UR - https://m2.mtmt.hu/api/publication/3248527 ID - 3248527 LA - English DB - MTMT ER - TY - JOUR AU - Komorowicz, Erzsébet AU - Balázs, N AU - Varga, Zoltán AU - Szabó, László AU - Bóta, Attila AU - Kolev, Kraszimir Nikolaev TI - Hyaluronic acid decreases the mechanical stability, but increases the lytic resistance of fibrin matrices JF - MATRIX BIOLOGY J2 - MATRIX BIOL VL - 63 PY - 2017 SP - 55 EP - 68 PG - 14 SN - 0945-053X DO - 10.1016/j.matbio.2016.12.008 UR - https://m2.mtmt.hu/api/publication/3155412 ID - 3155412 LA - English DB - MTMT ER - TY - CHAP AU - Pankaczi, F AU - Farkas, Zs AU - Halasy, V AU - Pólya, Sára Erzsébet AU - Lantos, Brigitta AU - Kovács, K AU - Klencsár, Zoltán AU - May, Z AU - Sándor, Z AU - Szabó, E Gy AU - Bódis, Eszter AU - Szabó, László AU - Kuzmann, Ernő AU - Homonnay, Zoltán AU - Tolnai, Gyula AU - Solti, Ádám AU - Fodor, Ferenc ED - Györgyey, János TI - Manufactured nanomaterials: new iron based fertilizers or potentially toxic agents? T2 - A Magyar Növénybiológiai Társaság XII. Kongresszusa PB - Magyar Növénybiológiai Társaság CY - Szeged SN - 9789631297362 PY - 2017 SP - 18 UR - https://m2.mtmt.hu/api/publication/3290848 ID - 3290848 LA - English DB - MTMT ER - TY - JOUR AU - Schwarczinger, Ildikó AU - Kolozsváriné Nagy, Judit AU - Künstler, András AU - Szabó, László AU - Geider, K AU - Király, Lóránt AU - Pogány, Miklós TI - Characterization of Myoviridae and Podoviridae family bacteriophages of Erwinia amylovora from Hungary-potential of application in biological control of fire blight JF - EUROPEAN JOURNAL OF PLANT PATHOLOGY J2 - EUR J PLANT PATHOL VL - 149 PY - 2017 IS - 3 SP - 639 EP - 652 PG - 14 SN - 0929-1873 DO - 10.1007/s10658-017-1214-9 UR - https://m2.mtmt.hu/api/publication/3297439 ID - 3297439 LA - English DB - MTMT ER - TY - JOUR AU - Balázs, N AU - Komorowicz, Erzsébet AU - Varga, Zoltán AU - Szabó, László AU - Bóta, Attila AU - Kolev, Kraszimir Nikolaev TI - A hialuronsav hatása a fibrin szerkezetére és a fibrinolízis iránti érzékenységére JF - METABOLIZMUS J2 - METABOLIZMUS VL - 14 ET - 0 PY - 2016 IS - 4 SP - 233 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/3129190 ID - 3129190 LA - Hungarian DB - MTMT ER - TY - CHAP AU - Fábián, Attila László AU - Földesiné, Füredi P K AU - Marglné Ambrus, Helga Márta AU - Jäger, Katalin AU - Szabó, László AU - Barnabás, Beáta ED - Veisz, Ottó Bálint ED - Polgár, Zsolt TI - Az n-butanol ultrastrukturális hatásainak vizsgálata kukorica portokkultúrában T2 - XXII. Növénynemesítési Tudományos Nap: összefoglalók PB - Magyar Tudományos Akadémia (MTA) CY - Budapest SN - 9789633960851 PY - 2016 SP - 79 PG - 127 UR - https://m2.mtmt.hu/api/publication/3092441 ID - 3092441 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Farkas, Ádám Zoltán AU - Farkas, Veronika Judit AU - Varjú, Imre AU - Szabó, László AU - Kolev, Kraszimir Nikolaev TI - A citrullináció csökkenti a fibrin mechanikai stabilitását és növeli a fibrinolízissel szembeni ellenállását JF - METABOLIZMUS J2 - METABOLIZMUS VL - 14 PY - 2016 IS - 4 SP - 235 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/3129175 ID - 3129175 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Farkas, Veronika Judit AU - Varjú, Imre AU - Kőhidai, László AU - Szabó, László AU - Polgár, Lívia AU - Chinopoulos, Christos AU - Kolev, Kraszimir Nikolaev TI - A Cyclophilin D a vérlemezke-funkció modulációján keresztül csökkenti a fibrinháló lítikus érzékenységét JF - METABOLIZMUS J2 - METABOLIZMUS VL - 14 PY - 2016 IS - 4 SP - 235 EP - 236 PG - 2 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/3129181 ID - 3129181 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Görög, Anna AU - Németh, Krisztián AU - Szabó, László AU - Mayer, Balázs AU - Silló, Pálma AU - Kolev, Kraszimir Nikolaev AU - Kárpáti, Sarolta TI - Decreased fibrinolytic potential and morphological changes of fibrin structure in dermatitis herpetiformis JF - JOURNAL OF DERMATOLOGICAL SCIENCE J2 - J DERMATOL SCI VL - 84 PY - 2016 IS - 1 SP - 17 EP - 23 PG - 7 SN - 0923-1811 DO - 10.1016/j.jdermsci.2016.07.005 UR - https://m2.mtmt.hu/api/publication/3090901 ID - 3090901 N1 - Cited By :9 Export Date: 22 June 2023 CODEN: JDSCE LA - English DB - MTMT ER - TY - JOUR AU - Homonnay, Zoltán AU - Tolnai, Gyula AU - Fodor, Ferenc AU - Solti, Ádám AU - Kovács, Krisztina AU - Kuzmann, Ernő AU - Ábrahám, A AU - Szabó, EG AU - Németh, Péter AU - Szabó, László AU - Klencsár, Zoltán TI - Iron oxide nanoparticles for plant nutrition? A preliminary Mössbauer study JF - HYPERFINE INTERACTIONS J2 - HYPERFINE INTERACT VL - 237 PY - 2016 IS - 1 PG - 9 SN - 0304-3843 DO - 10.1007/s10751-016-1334-1 UR - https://m2.mtmt.hu/api/publication/3101287 ID - 3101287 N1 - Institute of Chemistry, EötvösLoránd University, 1117 Pázmány P. s. 1/A, Budapest, Hungary Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, HAS, Magyar tudósokkörútja 2, Budapest, Hungary Institute of Biology, EötvösLoránd University, 1117 Pázmány P. s. 1/C, Budapest, Hungary Cited By :4 Export Date: 5 September 2019 CODEN: HYIND Correspondence Address: Homonnay, Z.; Institute of Chemistry, EötvösLoránd University, 1117 Pázmány P. s. 1/A, Hungary; email: homonnay@caesar.elte.hu LA - English DB - MTMT ER - TY - GEN AU - Klencsár, Zoltán AU - Tolnai, Gyula AU - Sándor, Zoltán AU - May, Zoltán AU - Szabó, Ervin Gy. AU - Németh, Péter AU - Szabó, László AU - Kovács, K AU - Kuzmann, Ernő AU - Homonnay, Zoltán AU - Pankaczi, F AU - Fülöp, Z AU - Farkas, Zs AU - Ludmerszki, E AU - Solti, Ádám AU - Fodor, Ferenc TI - IRON-BASED NANOPARTICLES AND THEIR EFFECTS ON PLANTS: OUTLOOK AND FIRST RESULTS PY - 2016 UR - https://m2.mtmt.hu/api/publication/3128017 ID - 3128017 LA - English DB - MTMT ER - TY - JOUR AU - Kolev, Kraszimir Nikolaev AU - Balázs, N AU - Varga, Zoltán AU - Szabó, László AU - Bóta, Attila AU - Komorowicz, Erzsébet TI - Hyaluronic acid decreases the mechanical stability, but increases the lytic resistance of fibrin JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 14 PY - 2016 IS - Suppl. 1 SP - 38 EP - 38 PG - 1 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/3071067 ID - 3071067 LA - English DB - MTMT ER - TY - JOUR AU - Komorowicz, Erzsébet AU - Balázs, N AU - Varga, Z AU - Szabó, László AU - Bóta, A AU - Kolev, Kraszimir Nikolaev TI - A különböző heparinok önálló ill. hiszton-neutralizáló hatása a fibrin szerkezetére és mechanikai tulajdonságaira JF - METABOLIZMUS J2 - METABOLIZMUS VL - 14 PY - 2016 IS - 4 SP - 242 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/3129185 ID - 3129185 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Tanka-Salamon, Anna AU - Komorowicz, Erzsébet AU - Szabó, László AU - Tenekedjiev, K AU - Kolev, Kraszimir Nikolaev TI - Free Fatty Acids Modulate Thrombin Mediated Fibrin Generation Resulting In Less Stable Clots JF - PLOS ONE J2 - PLOS ONE VL - 11 PY - 2016 IS - 12 PG - 14 SN - 1932-6203 DO - 10.1371/journal.pone.0167806 UR - https://m2.mtmt.hu/api/publication/3142741 ID - 3142741 AB - Upon platelet activation, free fatty acids are released at the stage of thrombus formation, but their effects on fibrin formation are largely unexplored. Our objective was to characterize the kinetic effects of fatty acids on thrombin activity, as well as the structural and mechanical properties of the resultant fibrin clots. Thrombin activity on fibrinogen was followed by turbidimetry and detailed kinetic characterization was performed using a fluorogenic short peptide substrate. The viscoelastic properties of fibrin were measured with rotatory oscillation rheometer, whereas its structure was analyzed with scanning electron microscopy (SEM). In turbidimetric assays of fibrin generation, oleate and stearate at physiologically relevant concentrations (60-600 mu M) produced a bell-shaped inhibitory dose response, increasing 10- to 30-fold the time to half-maximal clotting. Oleate inhibited thrombin activity on a short peptide substrate according to a mixed-type inhibitor pattern (a 9-fold increase of the Michaelis constant, Km and a 20% decrease of the catalytic constant), whereas stearate resulted in only a minor (15%) drop in the catalytic constant without any change in the Km. Morphometric analysis of SEM images showed a 73% increase in the median fiber diameter in the presence of stearate and a 20% decrease in the presence of oleate. Concerning the viscoelastic parameters of the clots, storage and loss moduli, maximal viscosity and critical shear stress decreased by 32-65% in the presence of oleate or stearate, but loss tangent did not change indicating decreased rigidity, higher deformability and decreased internal resistance to shear stress. Our study provides evidence that free fatty acids (at concentrations comparable to those reported in thrombi) reduce the mechanical stability of fibrin through modulation of thrombin activity and the pattern of fibrin assembly. LA - English DB - MTMT ER - TY - JOUR AU - Tanka-Salamon, Anna AU - Komorowicz, Erzsébet AU - Szabó, László AU - Tenekedjiev, K AU - Kolev, Kraszimir Nikolaev TI - A szabad zsírsavak hatása az alvadékképződés folyamatára és a kialakuló fibrinszerkezet mechanikai stabilitására JF - METABOLIZMUS J2 - METABOLIZMUS VL - 14 PY - 2016 IS - 4 SP - 246 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/3129187 ID - 3129187 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Fábián, Attila László AU - Földesiné, Füredi P K AU - Marglné Ambrus, Helga Márta AU - Jäger, Katalin AU - Szabó, László AU - Barnabás, Beáta TI - Effect of n-butanol and cold pretreatment on the cytoskeleton and the ultrastructure of maize microspores when cultured in vitro JF - PLANT CELL TISSUE AND ORGAN CULTURE J2 - PLANT CELL TISS ORG VL - 123 PY - 2015 SP - 257 EP - 271 PG - 15 SN - 0167-6857 DO - 10.1007/s11240-015-0829-9 UR - https://m2.mtmt.hu/api/publication/2956470 ID - 2956470 N1 - Print ISSN: 0167-6857 Online ISSN:1573-5044 Megjegyzés-25227493 Hiányzó Jelleg: 'JOUR\n\nArticle' Megjegyzés-25353276 N1 Funding Details: 80260, OTKA, Országos Tudományos Kutatási Alapprogramok LA - English DB - MTMT ER - TY - CHAP AU - Fábián, Attila László AU - Földesiné Füredi, Petra Katalin AU - Marglné Ambrus, Helga Márta AU - Jäger, Katalin AU - Szabó, László AU - Barnabás, Beáta ED - Veisz, Ottó Bálint TI - A hideg előkezelés és az n-butanol citológiai hatásai kukorica portokkultúrában. Fény a mezőgazdasági növények kutatásában: „Fény Éve” program TS - Fény a mezőgazdasági növények kutatásában: „Fény Éve” program T2 - XXI. Növénynemesítési Tudományos Napok PB - MTA Agrártudományi Kutatóközpont CY - Martonvásár SN - 9789638351432 PY - 2015 SP - 147 UR - https://m2.mtmt.hu/api/publication/2853032 ID - 2853032 LA - Hungarian DB - MTMT ER - TY - CONF AU - Jäger, Katalin AU - Fábián, Attila László AU - Polgári, Dávid AU - Szabó, László AU - Deák, C AU - Barnabás, Beáta AU - Papp, I TI - Identification of epidermal traits relevant to drought stress tolerance in wheat T2 - Multinational Congress on Microscopy PY - 2015 SP - 206 EP - 207 PG - 2 UR - https://m2.mtmt.hu/api/publication/3001263 ID - 3001263 LA - English DB - MTMT ER - TY - CHAP AU - Jäger, Katalin AU - Fábián, Attila László AU - Eitel, Gabriella AU - Szabó, László AU - Deák, Csilla AU - Barnabás, Beáta AU - Papp, István ED - Veisz, Ottó Bálint TI - Az aszálytűrés mértékének meghatározására alkalmas epidermális bélyegek azonosítása búzán fény- és elektronmikroszkópiával. Fény a mezőgazdasági növények kutatásában: „Fény Éve” program TS - Fény a mezőgazdasági növények kutatásában: „Fény Éve” program T2 - XXI. Növénynemesítési Tudományos Napok PB - MTA Agrártudományi Kutatóközpont CY - Martonvásár SN - 9789638351432 PY - 2015 SP - 140 UR - https://m2.mtmt.hu/api/publication/2853029 ID - 2853029 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Kovács, András AU - Sótonyi, Péter AU - Nagy, Anikó Ilona AU - Tenekedjiev, K AU - Wohner, Nikolett AU - Komorowicz, Erzsébet AU - Kovács, E AU - Nikolova, N AU - Szabó, László AU - Kovalszky, Ilona AU - Machovich, Raymund AU - Szelid, Zsolt László AU - Becker, Dávid AU - Merkely, Béla Péter AU - Kolev, Kraszimir Nikolaev TI - Ultrastructure and composition of thrombi in coronary and peripheral artery disease: correlations with clinical and laboratory findings JF - THROMBOSIS RESEARCH J2 - THROMB RES VL - 135 PY - 2015 IS - 4 SP - 760 EP - 766 PG - 7 SN - 0049-3848 DO - 10.1016/j.thromres.2015.02.004 UR - https://m2.mtmt.hu/api/publication/2834796 ID - 2834796 N1 - Department of Medical Biochemistry, Semmelweis University, 1094 Tûzoltó u. 37-47., Budapest, Hungary Heart and Vascular Center, Semmelweis University, Budapest, Hungary Department of Information Technology, Nikola Vaptsarov Naval Academy, Varna, Bulgaria Australian Maritime College, University of Tasmania, Launceston, Australia Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary Cited By :18 Export Date: 14 November 2022 CODEN: THBRA Correspondence Address: Kolev, K.; Department of Medical Biochemistry, 1094 Tûzoltó u. 37-47., Hungary; email: Krasimir.Kolev@eok.sote.hu LA - English DB - MTMT ER - TY - JOUR AU - Tanka-Salamon, A AU - Komorowicz, E AU - Szabó, László AU - Machovich, R AU - Kolev, Kraszimir Nikolaev TI - Free fatty acids modulate thrombin activity on fibrinogen and destabilise fibrin clots JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 13 PY - 2015 IS - Suppl. 2 SP - 838 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/2912377 ID - 2912377 LA - English DB - MTMT ER - TY - JOUR AU - Varjú, I AU - Longstaff, C AU - Szabó, László AU - Farkas, Veronika Judit AU - Farkas, Ádám Zoltán AU - Komorowicz, Erzsébet AU - Kolev, Kraszimir Nikolaev TI - Mechanisms by which DNA, histones and neutrophil extracellular traps stabilise clots towards mechanical and fibrinolytic breakdown JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 13 PY - 2015 IS - Suppl. 2 SP - 1 EP - 2 PG - 2 SN - 1538-7933 DO - 10.1111/jth.12993 UR - https://m2.mtmt.hu/api/publication/2912374 ID - 2912374 LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Longstaff, C AU - Szabó, László AU - Farkas, Ádám Zoltán AU - Farkas, Veronika Judit AU - Tanka-Salamon, Anna AU - Machovich, Raymund AU - Kolev, Kraszimir Nikolaev TI - DNA, histones and neutrophil extracellular traps exert anti-fibrinolytic effects in a plasma environment JF - THROMBOSIS AND HAEMOSTASIS J2 - THROMB HAEMOSTASIS VL - 113 PY - 2015 IS - 6 SP - 1289 EP - 1299 PG - 11 SN - 0340-6245 DO - 10.1160/TH14-08-0669 UR - https://m2.mtmt.hu/api/publication/2820969 ID - 2820969 N1 - PubMed adatbázis tévesen írja az oldalszám-adatokat (helyes: 1289-1299) GT LA - English DB - MTMT ER - TY - JOUR AU - Farkas, Ádám Zoltán AU - Farkas, Veronika Judit AU - Varjú, Imre AU - Szabó, László AU - Kolev, Kraszimir Nikolaev TI - A NEUTROFIL EXTRACELLULARIS CSAPDA (NET) KOMPONENSEI STABILIZÁLJÁK A PLAZMAALVADÉKOT JF - METABOLIZMUS J2 - METABOLIZMUS VL - 12 PY - 2014 IS - 4 SP - 248 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/2761749 ID - 2761749 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Güngör, Burcin AU - Gombos, Imre AU - Crul, Tim AU - Ayaydin, Ferhan AU - Szabó, László AU - Török, Zsolt AU - Mátés, Lajos AU - Vigh, László AU - Horváth, Ibolya TI - Rac1 participates in thermally induced alterations of the cytoskeleton, cell morphology and lipid rafts, and regulates the expression of heat shock proteins in B16F10 melanoma cells. JF - PLOS ONE J2 - PLOS ONE VL - 9 PY - 2014 IS - 2 SP - e89136 PG - 12 SN - 1932-6203 DO - 10.1371/journal.pone.0089136 UR - https://m2.mtmt.hu/api/publication/2574286 ID - 2574286 N1 - Open Access AB - Eukaryotic cells exhibit a characteristic response to hyperthermic treatment, involving morphological and cytoskeletal alterations and the induction of heat shock protein synthesis. Small GTPases of the Ras superfamily are known to serve as molecular switches which mediate responses to extracellular stimuli. We addressed here how small GTPase Rac1 integrates signals from heat stress and simultaneously induces various cellular changes in mammalian cells. As evidence that Rac1 is implicated in the heat shock response, we first demonstrated that both mild (41.5 degrees C) and severe (43 degrees C) heat shock induced membrane translocation of Rac1. Following inhibition of the activation or palmitoylation of Rac1, the size of its plasma membrane-bound pool was significantly decreased while the heat shock-induced alterations in the cytoskeleton and cell morphology were prevented. We earlier documented that the size distribution pattern of cholesterol-rich rafts is temperature dependent and hypothesized that this is coupled to the triggering mechanism of stress sensing and signaling. Interestingly, when plasma membrane localization of Rac1 was inhibited, a different and temperature independent average domain size was detected. In addition, inhibition of the activation or palmitoylation of Rac1 resulted in a strongly decreased expression of the genes of major heat shock proteins hsp25 and hsp70 under both mild and severe heat stress conditions. LA - English DB - MTMT ER - TY - JOUR AU - Jäger, Katalin AU - Fábián, Attila László AU - Eitel, Gabriella AU - Szabó, László AU - Deák, C AU - Barnabás, Beáta AU - Papp, István TI - A morpho-physiological approach differentiates bread wheat cultivars of contrasting tolerance under cyclic water stress JF - JOURNAL OF PLANT PHYSIOLOGY J2 - J PLANT PHYSIOL VL - 171 PY - 2014 IS - 14 SP - 1256 EP - 1266 PG - 11 SN - 0176-1617 DO - 10.1016/j.jplph.2014.04.013 UR - https://m2.mtmt.hu/api/publication/2711743 ID - 2711743 N1 - Cited By :17 Export Date: 20 February 2020 CODEN: JPPHE Agricultural Institute, Centre for Agricultural Research, Hungarian Academy of Sciences, Brunszvik u. 2, 2462 Martonvásár, Hungary Department of Functional and Structural Materials, Institute of Materials and Environmental Chemistry, Chemical Research Center, Hungarian Academy of Sciences, Pusztaszeri út 59-67, 1025 Budapest, Hungary Department of Plant Physiology and Plant Biochemistry, Faculty of Horticultural Science, Corvinus University of Budapest, Villányi út 29-43, 1118 Budapest, Hungary Cited By :20 Export Date: 15 June 2021 CODEN: JPPHE Correspondence Address: Papp, I.; Department of Plant Physiology and Plant Biochemistry, Faculty of Horticultural Science, Corvinus University of Budapest, Villányi út 29-43, 1118 Budapest, Hungary; email: istvan.papp2@uni-corvinus.hu AB - Leaf micromorphological traits and some physiological parameters with potential relevance to drought tolerance mechanisms were investigated in four selected winter wheat varieties. Plants were subjected to two cycles of drought treatment at anthesis. Yield components confirmed contrasting drought-sensitive and -tolerant behavior of the genotypes. Drought tolerance was associated with small flag leaf surfaces and less frequent occurrence of stomata. Substantial variation of leaf cuticular thickness was found among the cultivars. Thin cuticle coincided with drought sensitivity and correlated with a high rate of dark-adapted water loss from leaves. Unlike in Arabidopsis, thickening of the cuticular matrix in response to water deprivation did not occur. Water stress induced epicuticular wax crystal depositions preferentially on the abaxial leaf surfaces. According to microscopy and electrolyte leakage measurements from leaf tissues, membrane integrity was lost earlier or to a higher extent in sensitive than in tolerant genotypes. Cellular damage and a decline of relative water content of leaves in sensitive cultivars became distinctive during the second cycle of water deprivation. Our results indicate strong variation of traits with potential contribution to the complex phenotype of drought tolerance in wheat genotypes. The maintained membrane integrity and relative water content values during repeated water limited periods were found to correlate with drought tolerance in the selection of cultivars investigated. © 2014 Elsevier GmbH. LA - English DB - MTMT ER - TY - JOUR AU - Komorowicz, Erzsébet AU - Balázs, N AU - Varga, Zoltán AU - Bóta, Attila AU - Szabó, László AU - Kolev, Kraszimir Nikolaev TI - HIALURONSAV JELENLÉTÉBEN VASTAGABB SZÁLÚ, DE A PLAZMINOGÉN/PLAZMIN RENDSZERREL SZEMBEN MÉGIS ELLENÁLLÓBB FIBRINHÁLó KELETKEZIK JF - METABOLIZMUS J2 - METABOLIZMUS VL - 12 PY - 2014 IS - 4 SP - 252 EP - 253 PG - 2 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/2761750 ID - 2761750 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Kovács, András AU - Tenekedjiev, K AU - Wohner, Nikolett AU - Szabó, László AU - Kovalszky, I AU - Sótonyi, P AU - Szelid, Zsolt László AU - Nagy, A AU - Szabó, Gy AU - Merkely, B AU - Kolev, Kraszimir Nikolaev TI - AZ ARTÉRIÁS TROMBUSSZERKEZET KLINIKAI DETERMINÁNSAI: ULTRASTRUKTURÁLIS ES IMMUNFLUORESZCENS MEGFIGYELÉSEK JF - METABOLIZMUS J2 - METABOLIZMUS VL - 12 PY - 2014 IS - 4 SP - 253 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/2761751 ID - 2761751 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Kovács, András AU - Szabó, László AU - Longstaff, C AU - Tenekedjiev, K AU - Machovich, Raymund AU - Kolev, Kraszimir Nikolaev TI - Ambivalent roles of carboxypeptidase B in the lytic susceptibility of fibrin JF - THROMBOSIS RESEARCH J2 - THROMB RES VL - 133 PY - 2014 IS - 1 SP - 80 EP - 87 PG - 8 SN - 0049-3848 DO - 10.1016/j.thromres.2013.09.017 UR - https://m2.mtmt.hu/api/publication/2404078 ID - 2404078 LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Tenekedjiev, K AU - Keresztes, Zsófia AU - Pap, AE AU - Szabó, László AU - Thelwell, C AU - Longstaff, C AU - Machovich, Raymund AU - Kolev, Kraszimir Nikolaev TI - Fractal Kinetic Behavior of Plasmin on the Surface of Fibrin Meshwork JF - BIOCHEMISTRY J2 - BIOCHEMISTRY-US VL - 53 PY - 2014 IS - 40 SP - 6348 EP - 6356 PG - 9 SN - 0006-2960 DO - 10.1021/bi500661m UR - https://m2.mtmt.hu/api/publication/2733379 ID - 2733379 LA - English DB - MTMT ER - TY - CONF AU - Fábián, Attila László AU - Földesiné Füredi, Petra Katalin AU - Marglné Ambrus, Helga Márta AU - Jäger, Katalin AU - Szabó, László AU - Barnabás, Beáta TI - Effects of n-butanol on maize anther culture - androgenic response and cytological aspects T2 - European Frontiers of Plant Reproduction Research Conference PY - 2013 SP - 79 UR - https://m2.mtmt.hu/api/publication/2489545 ID - 2489545 LA - English DB - MTMT ER - TY - CONF AU - Jäger, Katalin AU - Miskó, A AU - Fábián, Attila László AU - Deák, Csilla AU - Polgári, Dávid AU - Szabó, László AU - Barnabás, Beáta AU - Papp, István TI - Identification of epidermal traits relevant to drought stress tolerance in wheat T2 - InterDrought-IV Conference PY - 2013 SP - 104 UR - https://m2.mtmt.hu/api/publication/2489651 ID - 2489651 LA - English DB - MTMT ER - TY - JOUR AU - Kovács, András AU - Tenekedjiev, K AU - Wohner, Nikolett AU - Szabó, László AU - Sótonyi, Péter AU - Szelid, Zsolt László AU - Nagy, Andrea AU - Szabó, G AU - Merkely, Béla Péter AU - Kolev, Kraszimir Nikolaev TI - Sign and shape: correlation of clinical findings and clot ultrastructure in arterial thrombi JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 11 PY - 2013 IS - Suppl.2 SP - 1 EP - 2 PG - 2 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/2343680 ID - 2343680 LA - English DB - MTMT ER - TY - JOUR AU - Longstaff, C AU - Varjú, Imre AU - Sótonyi, P AU - Szabó, László AU - Krumrey, M AU - Hoell, A AU - Bóta, Attila AU - Varga, Z AU - Komorowicz, Erzsébet AU - Kolev, Kraszimir Nikolaev TI - The effects of DNA and histones on fibrin clot structure-function and on the regulation of fibrinolysis JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 11 PY - 2013 IS - Suppl.2 SP - 45 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/2343704 ID - 2343704 LA - English DB - MTMT ER - TY - JOUR AU - Longstaff, C AU - Varjú, Imre AU - Sótonyi, Péter AU - Szabó, László AU - Krumrey, M AU - Hoell, A AU - Bóta, Attila AU - Varga, Zoltán AU - Komorowicz, Erzsébet AU - Kolev, Kraszimir Nikolaev TI - Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones JF - JOURNAL OF BIOLOGICAL CHEMISTRY J2 - J BIOL CHEM VL - 288 PY - 2013 IS - 10 SP - 6946 EP - 6956 PG - 11 SN - 0021-9258 DO - 10.1074/jbc.M112.404301 UR - https://m2.mtmt.hu/api/publication/2155890 ID - 2155890 N1 - Biotherapeutics Group, Haemostasis Section, National Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, United Kingdom Department of Medical Biochemistry, Semmelweis University, 1094 Budapest, Hungary Department of Vascular Surgery, Semmelweis University, 1122 Budapest, Hungary Institute of Materials and Environmental Chemistry, Institute of Molecular Pharmacology, Research Centre for Natural Sciences, 1025 Budapest, Hungary Department of Biological Nanochemsitry, Institute of Molecular Pharmacology, Research Centre for Natural Sciences, 1025 Budapest, Hungary Physikalisch-Technische Bundesanstalt (PTB), D-10587 Berlin, Germany Helmholtz-Zentrum Berlin (HZB), D-14109 Berlin, Germany Cited By :148 Export Date: 19 February 2022 CODEN: JBCHA Correspondence Address: Longstaff, C.; Biotherapeutics Group, , South Mimms, Potters Bar EN6 3QG, United Kingdom; email: colin.longstaff@nibsc.hpa.org.uk Chemicals/CAS: DNA, 9007-49-2; fibrin, 9001-31-4; heparin, 37187-54-5, 8057-48-5, 8065-01-8, 9005-48-5; histone, 9062-68-4; tissue plasminogen activator, 105913-11-9; Anticoagulants; DNA, 9007-49-2; Deoxyribonucleases, 3.1.-; Fibrin, 9001-31-4; Green Fluorescent Proteins, 147336-22-9; Heparin, 9005-49-6; Histones; Macromolecular Substances; Tissue Plasminogen Activator, 3.4.21.68 LA - English DB - MTMT ER - TY - JOUR AU - Rottenberger, Zsolt AU - Komorowicz, Erzsébet AU - Szabó, László AU - Bóta, Attila AU - Varga, Zoltán AU - Machovich, Raymund AU - Longstaff, C AU - Kolev, Kraszimir Nikolaev TI - Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 11 PY - 2013 IS - 3 SP - 529 EP - 538 PG - 10 SN - 1538-7933 DO - 10.1111/jth.12112 UR - https://m2.mtmt.hu/api/publication/2141407 ID - 2141407 LA - English DB - MTMT ER - TY - JOUR AU - Szigyártó, Imola Csilla AU - Szabó, László AU - Simándi, László TI - Kinetic studies on the manganese(II) complex catalyzed oxidation of epinephrine JF - JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL J2 - J MOL CATAL A-CHEM VL - 372 PY - 2013 SP - 66 EP - 71 PG - 6 SN - 1381-1169 DO - 10.1016/j.molcata.2013.02.003 UR - https://m2.mtmt.hu/api/publication/2233040 ID - 2233040 LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Kolev, Kraszimir Nikolaev AU - Longstaff, C AU - Szabó, László AU - Farkas, Veronika Judit AU - Farkas, Ádám Zoltán AU - Machovich, Raymund TI - The interplay of DNA, histones and neutrophil leukocytes with plasmin dependent lysis of plasma clots JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 11 PY - 2013 IS - Suppl. 2 SP - 35 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/2343698 ID - 2343698 LA - English DB - MTMT ER - TY - JOUR AU - Kolev, Kraszimir Nikolaev AU - Rottenberger, Zsolt AU - Komorowicz, Erzsébet AU - Szabó, László AU - Machovich, Raymund TI - Fibrinolysis at the interface of blood vessel wall and thrombi JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 10 PY - 2012 IS - 6 SP - e21 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/1980473 ID - 1980473 LA - English DB - MTMT ER - TY - JOUR AU - Kovács, András AU - Szabó, László AU - Machovich, Raymund AU - Kolev, Kraszimir Nikolaev TI - FIBRIN SZERKEZET MÓDOSÍTÁSA KARBOXIPEPTIDÁZ B-VEL ÉS ARGININNEL: HATÁSOK A FIBRINOLÍZISRE JF - HEMATOLÓGIA-TRANSZFUZIOLÓGIA J2 - HEMATOLÓGIA-TRANSZFUZIOLÓGIA VL - 45 PY - 2012 SP - 54 SN - 1786-5913 UR - https://m2.mtmt.hu/api/publication/2086596 ID - 2086596 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Longstaff, C AU - Varjú, Imre AU - Szabó, László AU - Thelwell, C AU - Kolev, Kraszimir Nikolaev TI - The effect of DNA and histones on fibrin structure and the regulation of plasminogen activation and fibrinolysis JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 10 PY - 2012 IS - 6 SP - e18 EP - e19 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/1980474 ID - 1980474 LA - English DB - MTMT ER - TY - JOUR AU - Rottenberger, Zsolt AU - Komorowicz, Erzsébet AU - Szabó, László AU - Machovich, Raymund AU - Kolev, Kraszimir Nikolaev TI - ÉRFALKOMPONENSEK HATÁSA A TROMBUS STABILITÁSÁRA JF - HEMATOLÓGIA-TRANSZFUZIOLÓGIA J2 - HEMATOLÓGIA-TRANSZFUZIOLÓGIA VL - 45 PY - 2012 SP - 67 SN - 1786-5913 UR - https://m2.mtmt.hu/api/publication/2086604 ID - 2086604 LA - Hungarian DB - MTMT ER - TY - BOOK ED - Szigyártó, Imola Csilla ED - Szabó, László ED - Simándi, László TI - Oxidoreductase mimics based on manganese- and iron complexes. Kinetics and Mechanism. abstact p C412-413 TS - abstact p C412-413 T3 - 40th International Conference on Coordination Chemistry ET - 0 CY - Valencia PY - 2012 SN - 139788469531808 UR - https://m2.mtmt.hu/api/publication/2109215 ID - 2109215 LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Longstaff, C AU - Szabó, László AU - Thelwell, C AU - Kolev, Kraszimir Nikolaev TI - DNS ÉS HISZTONOK HATÁSA A FIBRINSZERKEZETRE ÉS A FIBRINOLÍZISRE JF - HEMATOLÓGIA-TRANSZFUZIOLÓGIA J2 - HEMATOLÓGIA-TRANSZFUZIOLÓGIA VL - 45 PY - 2012 SP - 73 EP - 74 PG - 2 SN - 1786-5913 UR - https://m2.mtmt.hu/api/publication/2086599 ID - 2086599 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Gergely, András AU - Pászti, Zoltán AU - Mihály, Judith AU - Szabó, László AU - Kálmán, Erika TI - Transformation of multi-walled carbon nanotubes to amorphous nano-spheres, micron-size rods and flakes by oxidative sulfation reaction JF - DIAMOND AND RELATED MATERIALS J2 - DIAM RELAT MATER VL - 20 PY - 2011 IS - 5-6 SP - 826 EP - 832 PG - 7 SN - 0925-9635 DO - 10.1016/j.diamond.2011.03.033 UR - https://m2.mtmt.hu/api/publication/1615704 ID - 1615704 N1 - CODEN: DRMTE LA - English DB - MTMT ER - TY - JOUR AU - Longstaff, C AU - Thelwell, C AU - Williams, S AU - Silva, MMCG AU - Szabó, László AU - Kolev, Kraszimir Nikolaev TI - The interplay between tissue plasminogen activator domains and fibrin structures in the regulation of fibrinolysis: kinetic and microscopic studies JF - BLOOD J2 - BLOOD VL - 117 PY - 2011 IS - 2 SP - 661 EP - 668 PG - 8 SN - 0006-4971 DO - 10.1182/blood-2010-06-290338 UR - https://m2.mtmt.hu/api/publication/1382009 ID - 1382009 LA - English DB - MTMT ER - TY - BOOK AU - Szigyártó, Imola Csilla AU - Szabó, László AU - Simándi, László TI - Kinetic studies on the autooxidation of epinephrine catalyzed by manganese(II)complexes. abstact p 145 TS - abstact p 145 T3 - XXIII International Conference on Coordination and Bioinorganic Chemistry, ISSN 1335-308X ET - 0 CY - Smolenice PY - 2011 SN - 9788022735094 UR - https://m2.mtmt.hu/api/publication/2162666 ID - 2162666 LA - English DB - MTMT ER - TY - CONF AU - Szigyártó, Imola Csilla AU - Szabó, László AU - Simándi, László TI - Investigating oxidoreductase enzymes mimicking properties of manganese complex. abstact p 128 TS - abstact p 128 T2 - 11th International Symposium on Applied Bioinorganic Chemistry (ISABC) PY - 2011 PG - 1 UR - https://m2.mtmt.hu/api/publication/2162653 ID - 2162653 LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Sótonyi, Péter AU - Machovich, Raymund AU - Szabó, László AU - Tenekedjiev, K AU - Silva, M AU - Longstaff, C AU - Kolev, Kraszimir Nikolaev TI - Hindered dissolution of fibrin formed under mechanical stress JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 9 PY - 2011 IS - 5 SP - 979 EP - 986 PG - 8 SN - 1538-7933 DO - 10.1111/j.1538-7836.2011.04203.x UR - https://m2.mtmt.hu/api/publication/1409057 ID - 1409057 LA - English DB - MTMT ER - TY - JOUR AU - Wohner, Nikolett AU - Sótonyi, Péter AU - Machovich, Raymund AU - Szabó, László AU - Tenekedjiev, K AU - Silva, MMCG AU - Longstaff, C AU - Kolev, Kraszimir Nikolaev TI - Lytic resistance of fibrin containing red blood cells JF - ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY J2 - ARTERIOSCL THROM VAS VL - 31 PY - 2011 IS - 10 SP - 2306 EP - 2313 PG - 8 SN - 1079-5642 DO - 10.1161/ATVBAHA.111.229088 UR - https://m2.mtmt.hu/api/publication/1618514 ID - 1618514 N1 - Department of Medical Biochemistry, Semmelweis University, Túzoltóu. 37-47, 1094 Budapest, Hungary Department of Vascular Surgery, Semmelweis University, Budapest, Hungary Chemical Research Center, Hungarian Academy of Sciences, Budapest, Hungary Department of Information Technologies, Nikola Yonkov Vaptsarov Naval Academy, Varna, Bulgaria Biotherapeutics, Haemostasis Section, National Institute for Biological Standards and Control, South Mimms, United Kingdom Cited By :82 Export Date: 14 November 2022 CODEN: ATVBF Correspondence Address: Kolev, K.; Department of Medical Biochemistry, Túzoltóu. 37-47, 1094 Budapest, Hungary; email: krasimir.kolev@eok.sote.hu LA - English DB - MTMT ER - TY - JOUR AU - Wohner, Nikolett AU - Szabó, László AU - Machovich, Raymund AU - Silva, M AU - Longstaff, C AU - Kolev, Kraszimir Nikolaev TI - Red blood cells confer lytic resistance to fibrin JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 9 PY - 2011 IS - Suppl. 2 SP - 11 EP - 12 PG - 2 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/1513482 ID - 1513482 LA - English DB - MTMT ER - TY - JOUR AU - Kolev, Kraszimir Nikolaev AU - Wohner, Nikolett AU - Szabó, László AU - Machovich, Raymund TI - Gátolt fibrinolízis vörösvértest-tartalmú fibrinben JF - MAGYAR BELORVOSI ARCHIVUM J2 - MBA VL - 63 PY - 2010 IS - 5 SP - 369 EP - 370 PG - 2 SN - 0133-5464 UR - https://m2.mtmt.hu/api/publication/1410941 ID - 1410941 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Kolev, Kraszimir Nikolaev AU - Varjú, Imre AU - Szabó, László AU - Machovich, Raymund AU - Silva, M AU - Longstaff, C TI - Hampered dissolution of fibrin formed under mechanical stress JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 8 PY - 2010 IS - Suppl. 1 SP - 7 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/1369746 ID - 1369746 LA - English DB - MTMT ER - TY - JOUR AU - Rábai, Gyöngyi AU - Szilágyi, Nóra AU - Sótonyi, Péter AU - Kovalszky, Ilona AU - Szabó, László AU - Machovich, Raymund AU - Kolev, Kraszimir Nikolaev TI - Contribution of neutrophil elastase to the lysis of obliterative thrombi in the context of their platelet and fibrin content JF - THROMBOSIS RESEARCH J2 - THROMB RES VL - 126 PY - 2010 IS - 2 SP - e94 EP - e101 SN - 0049-3848 DO - 10.1016/j.thromres.2010.05.007 UR - https://m2.mtmt.hu/api/publication/1346135 ID - 1346135 LA - English DB - MTMT ER - TY - BOOK AU - Szigyártó, Imola Csilla AU - Szabó, László AU - Simándi, László TI - Functional models for catechol oxidase and phenoxazinone synthase. abstact p 132 TS - abstact p 132 T3 - 5th Central European Conference – Chemistry towards Biology ET - 0 CY - Primošten PY - 2010 UR - https://m2.mtmt.hu/api/publication/2162677 ID - 2162677 LA - English DB - MTMT ER - TY - JOUR AU - Varjú, Imre AU - Szabó, László AU - Machovich, Raymund AU - Kolev, Kraszimir Nikolaev TI - A mechanikai stressz gátolja a fibrin oldását JF - MAGYAR BELORVOSI ARCHIVUM J2 - MBA VL - 63 PY - 2010 IS - 5 SP - 384 SN - 0133-5464 UR - https://m2.mtmt.hu/api/publication/1410942 ID - 1410942 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Williams, SC AU - Kolev, Kraszimir Nikolaev AU - Szabó, László AU - Silva, M AU - Longstaff, C TI - Fibrin structure and the regulation of tissue plasminogen activator (tPA) binding and potency JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 8 PY - 2010 IS - Suppl. 1 SP - 15 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/1369751 ID - 1369751 LA - English DB - MTMT ER - TY - JOUR AU - Wohner, Nikolett AU - Keresztes, Zsófia AU - Sótonyi, Péter AU - Szabó, László AU - Komorowicz, Erzsébet AU - Machovich, Raymund AU - Kolev, Kraszimir Nikolaev TI - Neutrophil granulocyte-dependent proteolysis enhances platelet adhesion to the arterial wall under high-shear flow JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 8 PY - 2010 IS - 7 SP - 1624 EP - 1631 PG - 8 SN - 1538-7933 DO - 10.1111/j.1538-7836.2010.03890.x UR - https://m2.mtmt.hu/api/publication/1336231 ID - 1336231 LA - English DB - MTMT ER - TY - JOUR AU - Bakos, Ferenc AU - Szabó, László AU - Olmedilla, A AU - Barnabás, Beáta TI - Histological comparison between wheat embryos developing in vitro from isolated zygotes and those developing in vivo JF - SEXUAL PLANT REPRODUCTION J2 - SEX PLANT REPROD VL - 29 PY - 2009 IS - 1 SP - 15 EP - 25 PG - 11 SN - 0934-0882 DO - 10.1007/s00497-008-0087-7 UR - https://m2.mtmt.hu/api/publication/1231002 ID - 1231002 N1 - WoS:hiba:000263507900003 2020-08-25 23:12 kötet nem egyezik Plant Cell Biology Department, Agricultural Research Institute, Hungarian Academy of Sciences, P.O. Box 19, Martonvásár 2462, Hungary Department of Plant Biochemistry, Cell and Molecular Biology, EEZ (CSIC), Professor Albareda 1, Granada 18008, Spain Chemical Research Center, Hungarian Academy of Sciences, P.O. Box 17, Budapest 1525, Hungary Cited By :4 Export Date: 3 February 2021 CODEN: SPLRE Correspondence Address: Barnabás, B.; Plant Cell Biology Department, P.O. Box 19, Martonvásár 2462, Hungary; email: barnabasb@mail.mgki.hu LA - English DB - MTMT ER - TY - JOUR AU - Longstaff, C AU - Szabó, László AU - Kolev, Kraszimir Nikolaev TI - Kinetics of fibrin dissolution initiated by plasminogen activation in fibrin matrices of varying architecture JF - JOURNAL OF THROMBOSIS AND HAEMOSTASIS J2 - J THROMB HAEMOST VL - 7 PY - 2009 IS - Suppl.2 SP - 130 SN - 1538-7933 UR - https://m2.mtmt.hu/api/publication/1235757 ID - 1235757 LA - English DB - MTMT ER - TY - JOUR AU - Koósné, Szathmáry Erzsébet AU - Novák, Nádudvari J AU - Szabó, László AU - Tóbiás, István AU - Balázs, Ervin AU - Palkovics, László TI - Characterization of a natural Plum pox virus isolate bearing a truncated coat protein JF - ARCHIVES OF VIROLOGY J2 - ARCH VIROL VL - 154 PY - 2009 IS - 1 SP - 141 EP - 145 PG - 5 SN - 0304-8608 DO - 10.1007/s00705-008-0281-9 UR - https://m2.mtmt.hu/api/publication/126442 ID - 126442 LA - English DB - MTMT ER - TY - GEN AU - Kálmán, Erika AU - Csanády Andrásné Bodoky, Ágnes AU - Kálmánné, Herr Franciska AU - Felhősi, Ilona AU - Tompos, András AU - Tálas, Emilia AU - Sajó, István AU - Hargitai, Hajnalka AU - Papp, Katalin AU - Németh, Péter AU - Gőbölös, Sándor AU - Szabó, László AU - Tolnai, Gyula AU - Berényi, Szilvia AU - Trif, László TI - Tanulmányok az NKFP-070-A2-METANANO-0-07101200730 „Környezetvédelmi és biztonságtechnikai célú, nemesfém nanoporokon alapuló inovatív termékek (szűrők, szenzorok, katalizátorok) fejlesztése” című téma keretében PY - 2008 UR - https://m2.mtmt.hu/api/publication/1225074 ID - 1225074 N1 - [Tanulmány] LA - Hungarian DB - MTMT ER - TY - CONF AU - Németh, P AU - Csanády Andrásné Bodoky, Ágnes AU - Papp, K AU - Cs Pintér, A AU - Szabó, László AU - Pászti, Zoltán AU - Tóth, A AU - Hargitai, Hajnalka AU - Kálmán, E ED - Barlai, Gábor TI - The influence of roughening on the uniformity of thin silicon containing protective layers on galvanized steel surfaces produced by different coating methods T2 - 1st Functional Nanocoatings Conference C1 - Budapest PY - 2008 SP - 137 UR - https://m2.mtmt.hu/api/publication/1227383 ID - 1227383 LA - English DB - MTMT ER - TY - JOUR AU - Németh, Péter AU - Csanády Andrásné Bodoky, Ágnes AU - Papp, Katalin AU - Ismeretlen, Szerző AU - Szabó, László AU - Pászti, Zoltán AU - Tóth, AL AU - Kálmán, Erika TI - The investigation of Thin Protecting Layers on Roughened Galvanized Steel Surfaces produced by Diffferent Coating Methods JF - MATERIALS SCIENCE FORUM J2 - MATER SCI FORUM VL - 589 PY - 2008 SP - 433 EP - 438 PG - 6 SN - 0255-5476 DO - 10.4028/www.scientific.net/MSF.589.433 UR - https://m2.mtmt.hu/api/publication/138240 ID - 138240 N1 - Funding Agency and Grant Number: EU Research Fund for Coal and Steel Funding text: The authors are grateful for the samples to Sam Siau and the Thin Film Project of the EU Research Fund for Coal and Steel, further for the support of the GVOP-ALUNANO-3.1.1-2004 and GVOP-3.2.1 2004 04 0061 /3.0. Thanks to P. M. Nagy for the AFM and Nanoindentation measurements. AB - Protective, chromate substitute thin layers on roughened galvanized surfaces produced at OCAS (Arcelor, Belgium) were characterized and compared using Scanning Electron Microscopy (SEM+EDS), Atomic Force Microscopy (AFM), Nanoindentation and X-ray Photoemission Spectroscopy (XPS). EDX maps, line scans and point analyses obtained at various places of the surfaces have shown differences between the CVD and silane nanolayers in the matter of thickness distribution and composition. At cross-section specimens the thickness of the layers could be shown. The hardness differences caused by layer thickness variations are hard to follow by nanoindentation as the penetration depth of the indenter is much larger than the thickness of the coatings. XPS measurements can distinguish between the chemical states of silicon in CVD and silane coatings. LA - English DB - MTMT ER - TY - JOUR AU - Stiller, Ibolya AU - Dulai, Sándor András AU - Kondrák, Mihály Attila AU - Tarnai, R AU - Szabó, László AU - Toldi, Ottó AU - Bánfalvi, Zsófia TI - Effects of drought on water content and photosynthetic parameters in potato plants expressing the trehalose-6-phosphate synthase gene of Saccharomyces cerevisiae. JF - PLANTA J2 - PLANTA VL - 227 PY - 2008 IS - 2 SP - 299 EP - 308 PG - 10 SN - 0032-0935 DO - 10.1007/s00425-007-0617-9 UR - https://m2.mtmt.hu/api/publication/1160435 ID - 1160435 AB - Two transgenic potato lines, T1 and T2, expressing the trehalose-6-phosphate synthase (TPS1) gene of yeast were isolated. In our experimental approach, we applied two novelties, namely the fusion of the drought-inducible promoter StDS2 to TPS1 and a marker-free transformation method. In contrast to the expected drought-induced expression, only a very low constitutive TPS1 expression was detected in the transgenic lines, probably due to chromosomal position effects. The observed expression pattern, however, was sufficient to alter the drought response of plants. Detached leaves of T1 and T2 showed an 8 h delay in wilting compared to the non-transformed control. Potted plants of T1 and T2 kept water 6 days longer than control plants and maintained high stomatal conductance and a satisfactory rate of net photosynthesis. During drought treatment, CO2 assimilation rate measured at saturating CO2 level was maintained at maximum level for 6-9 days in transgenic plants while it decreased rapidly after 3 days in the wild type plants. Under optimal growth conditions, lower CO2 fixation was detected in the transgenic than in the control plants. Stomatal densities of T1 and T2 leaves were reduced by 30-40%. This may have contributed to the lower CO2 fixation rate and altered drought response. LA - English DB - MTMT ER - TY - CONF AU - Bakos, Ferenc AU - Szabó, László AU - Barnabás, Beáta ED - Heszky, László ED - Kiss, J TI - Az in vivo embriófejlődés reprodukálhatósága a búza zigóták in vitro tenyészeteiben. T2 - XIII. Növénynemesítési Tudományos Napok : 2007. március 12., Magyar Tudományos Akadémia Budapest : összefoglalók PB - MTA Agrártudományok Osztálya Növénynemesítési Tudományos Bizottság C1 - Budapest PY - 2007 SP - 48 UR - https://m2.mtmt.hu/api/publication/1109543 ID - 1109543 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Baranyi, M AU - Hiripi, László AU - Szabó, László AU - Catunda, AP AU - Harsanyi, I AU - Komaromy, P AU - Bősze, Zsuzsanna TI - Isolation and some effects of functional, low-phenylalanine kappa-casein expressed in the milk of transgenic rabbits. JF - JOURNAL OF BIOTECHNOLOGY J2 - J BIOTECHNOL VL - 128 PY - 2007 IS - 2 SP - 383 EP - 392 PG - 10 SN - 0168-1656 DO - 10.1016/j.jbiotec.2006.10.016 UR - https://m2.mtmt.hu/api/publication/1151779 ID - 1151779 N1 - PubMed ID: 17157946 UR: http://www.scopus.com/inward/record.url?eid=2-s2.0-33846206753&partnerID=40 AB - Patients suffering certain metabolic diseases (e.g. phenylketonuria) need a low-phenylalanine diet throughout their lives. Transgenic rabbits were created to express low-phenylalanine kappa-casein in their milk. The aim was to demonstrate for the first time the feasibility of producing a modified milk protein in addition to normal milk proteins. A gene construct containing the coding region of the rabbit kappa-casein gene was modified by site-specific oligonucleotide directed mutagenesis. Four of the five phenylalanine amino acids present in the mature protein were mutated and the gene construct was used to create two transgenic rabbit lines. The transgenic rabbits produced the recombinant kappa-casein at a high level in their milk causing a reduction in the average size of the casein micelles. The low-phenylalanine kappa-casein was digestible with chymosin and it was separated from its native counterpart and from the other milk proteins by a one-step HPLC method on a reversed-phase column. In the future, low-phenylalanine casein produced in transgenic animals could be used as dietary replacements to meet the special requirements of certain consumer groups. LA - English DB - MTMT ER - TY - CHAP AU - Hiripi, László AU - Baranyi, M AU - Carnwath, J W AU - Niemann, H AU - Bodrogi, Lilla AU - Raaben, W AU - Brands, R AU - Seinen, W AU - Lemos, APC AU - Bender, B AU - Szabó, László AU - Bősze, Zs TI - Transgenic rabbit as a models for producing bilogically active human recombinant proteins T2 - Genetika SN - 9619053443 PY - 2007 SP - 76 UR - https://m2.mtmt.hu/api/publication/2999905 ID - 2999905 LA - English DB - MTMT ER - TY - JOUR AU - Marglné Ambrus, Helga Márta AU - Darkó, Éva AU - Szabó, László AU - Bakos, Ferenc AU - Király, Zoltán AU - Barnabás, Beáta TI - In vitro microspore selection in maize anther culture with oxidative-stress stimulators. JF - PROTOPLASMA J2 - PROTOPLASMA VL - 228 PY - 2006 IS - 1-3 SP - 87 EP - 94 PG - 8 SN - 0033-183X DO - 10.1007/s00709-006-0159-1 UR - https://m2.mtmt.hu/api/publication/1021061 ID - 1021061 LA - English DB - MTMT ER - TY - CONF AU - Barnabás, Beáta AU - Jäger, Katalin AU - Szabó, László AU - Bakos, Ferenc AU - Király, Zoltán ED - Marton, L Csaba TI - Improvement of anther culture technique for maize breeding. History and future. T2 - XXth International Conference of the EUCARPIA Maize and Sorghum PY - 2006 SP - 51 UR - https://m2.mtmt.hu/api/publication/1018887 ID - 1018887 LA - English DB - MTMT ER - TY - CHAP AU - Salamon, P AU - Szabó, László AU - Palkovics, László ED - Horváth, J ED - Haltrich, Attila-Krisztián ED - Molnár, J TI - Első adatok a kaktuszfélék (Fam.: Cactaceae) vírusos betegségeiről Magyarországon T2 - 52. Növényvédelmi Tudományos Napok PB - Földművelésügyi és Vidékfejlesztési Minisztérium (FVM) CY - Budapest T3 - Növényvédelmi Tudományos Napok, ISSN 0231-2956 ; 52. PY - 2006 SP - 95 UR - https://m2.mtmt.hu/api/publication/1148553 ID - 1148553 LA - Hungarian DB - MTMT ER - TY - CONF AU - Marglné Ambrus, Helga Márta AU - Darkó, Éva AU - Szabó, László AU - Bakos, Ferenc AU - Király, Zoltán AU - Barnabás, Beáta ED - Kertész, Zoltán TI - Mikrospórák biotechnológiai alkalmazása oxidatív stressz-tolerancia fokozásának céljából. T2 - XI. Növénynemesítési Tudományos Napok : 2005. március 3-4., Magyar Tudományos Akadémia Budapest : összefoglalók PB - Magyar Tudományos Akadémia (MTA) C1 - Budapest PY - 2005 SP - 27 UR - https://m2.mtmt.hu/api/publication/1020752 ID - 1020752 LA - Hungarian DB - MTMT ER - TY - CONF AU - Marglné Ambrus, Helga Márta AU - Darkó, Éva AU - Szabó, László AU - Bakos, Ferenc AU - Barnabás, Beáta TI - In vitro selection of maize microspores to improve oxidative stress tolerance in plants. T2 - XI. International Palynology Congress. C1 - Granada PY - 2005 SP - 321 UR - https://m2.mtmt.hu/api/publication/1020738 ID - 1020738 LA - English DB - MTMT ER - TY - JOUR AU - Baranyi, M AU - Lemos, APC AU - Bodrogi, Lilla AU - Bender, B AU - Szabó, László AU - Hiripi, László AU - Bősze, Zsuzsanna TI - Expression of low-phenylalanine kappa-casein in the milk of transgenic rabbits JF - FEBS JOURNAL J2 - FEBS J VL - 272 PY - 2005 IS - SU 1 SP - 509 EP - 509 PG - 1 SN - 1742-464X UR - https://m2.mtmt.hu/api/publication/2094672 ID - 2094672 N1 - Megjegyzés-23643838 SU 1 LA - English DB - MTMT ER - TY - JOUR AU - Obert, B AU - Szabó, László AU - Mitykó, J AU - Pretova, A AU - Barnabás, Beáta TI - Morphological events in cultures of mechanically isolated maize microspores. JF - IN VITRO CELLULAR AND DEVELOPMENTAL BIOLOGY-PLANT J2 - IN VITRO CELL DEV-PL VL - 41 PY - 2005 SP - 775 EP - 782 PG - 8 SN - 1054-5476 DO - 10.1079/IVP2005701 UR - https://m2.mtmt.hu/api/publication/1021049 ID - 1021049 LA - English DB - MTMT ER - TY - CONF AU - Palkovics, László AU - Novák, Nádudvari J AU - Szabó, László AU - Koósné, Szathmáry Erzsébet AU - Tóbiás, István AU - Balázs, Ervin TI - Characterization of a Plum Pox Virus Isolate with Truncated Coat Protein T2 - 13th International Congress of Virology PY - 2005 UR - https://m2.mtmt.hu/api/publication/1147216 ID - 1147216 LA - English DB - MTMT ER - TY - CONF AU - Marglné Ambrus, Helga Márta AU - Darkó, Éva AU - Szabó, László AU - Bakos, Ferenc AU - Király, Zoltán AU - Barnabás, Beáta ED - Sutka, József TI - Oxidatív stressz toleráns DH kukorica genotípusok előállítása in vitro mikrospóra szelekcióval. T2 - X. Növénynemesítési Tudományos Napok PB - Magyar Tudományos Akadémia (MTA) C1 - Budapest PY - 2004 SP - 34 UR - https://m2.mtmt.hu/api/publication/1020744 ID - 1020744 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Lovas, A AU - Bimbo, A AU - Szabó, László AU - Bánfalvi, Zsófia TI - Antisense repression of StubGAL83 affects root and tuber development in potato. JF - PLANT JOURNAL J2 - PLANT J VL - 33 PY - 2003 IS - 1 SP - 139 EP - 147 PG - 9 SN - 0960-7412 DO - 10.1046/j.1365-313X.2003.016015.x UR - https://m2.mtmt.hu/api/publication/1160429 ID - 1160429 AB - StubGAL83 is a potato gene that encodes the beta-subunit of a protein kinase complex similar to the yeast SNF1, and the mammalian AMPK complexes that are modulated by changes in the cellular AMP/ATP ratio and are important regulators of metabolic and stress responses. Here we show that the expression of StubGAL83 in potato foliage is much higher in the dark than in the light and can be repressed by metabolisable sugars in the dark. The amounts of StubGAL83 mRNA are higher in sink than in source leaves. To unravel the role of StubGAL83, transgenic potato plants expressing a part of the StubGAL83 cDNA in antisense orientation under the control of the constitutive CaMV35S promoter were generated. Northern analysis revealed a reduction up to 90-95% in StubGAL83 mRNA accumulation in leaves of seven lines. Five out of these seven lines exhibited a reduction of StubGAL83 mRNA levels also in root and tuber tissues. Independent on the type of repression, the transgenic lines showed a delay in rooting and an increased sensitivity to salt stress. The roots were stunted and possessed less pronounced tap roots than the controls albeit with different severity in the different transgenic lines. The root cells were smaller and some of them had irregular shape. Tuberisation of the antisense-StubGAL83 lines was delayed, the size of the tubers was reduced while the number of tubers per plant was increased. These results together suggest that StubGAL83 affects root and tuber development probably by altering the metabolic status of the leaves. LA - English DB - MTMT ER -