@article{MTMT:34501021,
	title = {Chemical composition, antimicrobial and antiproliferative activity of the essential oil from Ambrosia artemisiifolia L},
	url = {https://m2.mtmt.hu/api/publication/34501021},
	author = {Kovács, Balázs and Szemerédi, Nikoletta and Csikós, Orsolya and Kiss, Tivadar and Veres, Katalin and Spengler, Gabriella and Csupor-Löffler, Boglárka and Csupor, Dezső},
	doi = {10.1080/10412905.2024.2303449},
	journal-iso = {J ESSENT OIL RES},
	journal = {JOURNAL OF ESSENTIAL OIL RESEARCH},
	volume = {36},
	unique-id = {34501021},
	issn = {1041-2905},
	year = {2024},
	eissn = {2163-8152},
	pages = {30-42},
	orcid-numbers = {Kiss, Tivadar/0000-0003-3538-377X; Veres, Katalin/0000-0001-7108-3622; Spengler, Gabriella/0000-0001-8085-0950; Csupor, Dezső/0000-0002-4088-3333}
}

@article{MTMT:33742452,
	title = {Isolation of compounds from the roots of Ambrosia artemisiifolia and their effects on human cancer cell lines},
	url = {https://m2.mtmt.hu/api/publication/33742452},
	author = {Ferencz, Elek and Spengler, Gabriella and Zupkó, István and Vollár, Martin and Zomborszki, Zoltán Péter and Kúsz, Norbert and Hohmann, Judit and Kovács, Balázs and Csupor, Dezső and Laczkó-Zöld, Eszter and Csupor-Löffler, Boglárka},
	doi = {10.1515/znc-2022-0239},
	journal-iso = {Z NATURFORSCH C},
	journal = {ZEITSCHRIFT FÜR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES},
	volume = {78},
	unique-id = {33742452},
	issn = {0939-5075},
	abstract = {Common ragweed (Ambrosia artemisiifolia L.) is an invasive plant in Europe with spreading use in the contemporary folk medicine. The chemical composition of the above-ground parts is extensively studied, however, the metabolites of the roots are less discovered. By multiple chromatographic purification of the root extracts, we isolated thiophene A (1), n-dodecene (2), taraxerol-3-O-acetate (3), α-linoleic acid (4), (+)-pinoresinol (5), and thiophene E (7,10-epithio-7,9-tridecadiene-3,5,11-triyne-1,2-diol) (6). The 1H NMR data published earlier for 1 were supplemented together with the assignment of 13C NMR data. Thiophene E (6), which is reported for the first time from this species, exerted cytotoxic and antiproliferative effects on A-431 epidermoid skin cancer cells, whereas taraxerol-3-O-acetate (3) and α-linoleic acid (4) had slight antiproliferative effect on gynecological cancer cell lines. Thiophene E (6) and taraxerol-3-O-acetate (3) displayed antiproliferative and cytotoxic effects on MRC-5 fibroblast cells. Thiophene E (6) exerted weak antibacterial activity (MIC 25 μg/mL) on MRSA ATCC 43300, on Staphylococcus aureus ATCC 25923, Escherichia coli AG100 and E. coli ATCC 25922 both thiophenes were inactive. Although the isolated compounds exerted no remarkable cytotoxic or antiproliferative activities, the effects on MRC-5 fibroblast cells highlight the necessity of further studies to support the safety of ragweed root.},
	keywords = {lignan; RAGWEED; Thiophene; Ambrosia artemisiifolia; sterol},
	year = {2023},
	eissn = {1865-7125},
	pages = {299-305},
	orcid-numbers = {Spengler, Gabriella/0000-0001-8085-0950; Zupkó, István/0000-0003-3243-5300; Zomborszki, Zoltán Péter/0000-0002-7412-9793; Kúsz, Norbert/0000-0002-9973-6442; Hohmann, Judit/0000-0002-2887-6392; Csupor, Dezső/0000-0002-4088-3333}
}

@article{MTMT:33684363,
	title = {Antiproliferative sesquiterpene lactones from Ambrosia artemisiifolia L},
	url = {https://m2.mtmt.hu/api/publication/33684363},
	author = {Kovács, Balázs and Szemerédi, Nikoletta and Kúsz, Norbert and Kiss, Tivadar and Csupor-Löffler, Boglárka and Tsai, Y-C and Spengler, Gabriella and Csupor, Dezső},
	doi = {10.1055/s-0042-1759242},
	journal-iso = {PLANTA MED},
	journal = {PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH},
	volume = {88},
	unique-id = {33684363},
	issn = {0032-0943},
	year = {2022},
	eissn = {1439-0221},
	pages = {1533-1533},
	orcid-numbers = {Kúsz, Norbert/0000-0002-9973-6442; Kiss, Tivadar/0000-0003-3538-377X; Spengler, Gabriella/0000-0001-8085-0950; Csupor, Dezső/0000-0002-4088-3333}
}

@CONFERENCE{MTMT:33100213,
	title = {Sesquiterpene lactones of Ambrosia artemisiifolia},
	url = {https://m2.mtmt.hu/api/publication/33100213},
	author = {Kovács, Balázs},
	booktitle = {3rd Symposium of Young Researchers on Pharmacognosy},
	doi = {10.14232/syrpharmacognosy.2022.b1},
	unique-id = {33100213},
	year = {2022},
	pages = {16-16}
}

@article{MTMT:33049439,
	title = {Antiproliferative and cytotoxic effects of sesquiterpene lactones isolated from Ambrosia artemisiifolia on human adenocarcinoma and normal cell lines.},
	url = {https://m2.mtmt.hu/api/publication/33049439},
	author = {Kovács, Balázs and Szemerédi, Nikoletta and Kúsz, Norbert and Kiss, Tivadar and Csupor-Löffler, Boglárka and Tsai, Yu-Chi and Rácz, Bálint and Spengler, Gabriella and Csupor, Dezső},
	doi = {10.1080/13880209.2022.2103574},
	journal-iso = {PHARM BIOL},
	journal = {PHARMACEUTICAL BIOLOGY},
	volume = {60},
	unique-id = {33049439},
	issn = {1388-0209},
	abstract = {Ambrosia artemisiifolia L. (Asteraceae) contains sesquiterpene lactones as characteristic secondary metabolites. Many of these compounds exert antiproliferative and cytotoxic effects.To isolate the sesquiterpene lactones from the aerial part of A. artemisiifolia and to elucidate their cytotoxic, antiproliferative and antibacterial effects.The compounds were identified by one-dimensional (1D) and 2D NMR, HR-MS spectroscopy from the methanol extract. Isolated compounds were investigated for their cytotoxic and antiproliferative effects on human colonic adenocarcinoma cell lines and human embryonal lung fibroblast cell line using MTT assay. The selectivity of the sesquiterpenes was calculated towards the normal cell line. To check the effect of drug interactions between compounds and doxorubicin, multidrug-resistant Colo 320 cells were used.A new seco-psilostachyinolide derivative, 1,10-dihydro-1'-noraltamisin, and seven known compounds were isolated from the methanol extract. Acetoxydihydrodamsin had the most potent cytotoxic effect on sensitive (Colo205) cell line (IC50 = 7.64 µM), also the strongest antiproliferative effect on Colo205 (IC50 = 5.14 µM) and Colo320 (IC50 = 3.67 µM) cell lines. 1'-Noraltamisin (IC50 = 8.78 µM) and psilostachyin (IC50 = 5.29 µM) showed significant antiproliferative effects on the multidrug-resistant Colo320 cell line and had moderate selectivity against human embryonal lung fibroblast cell line. Psilostachyin C exhibited cytotoxic effects on Colo205 cells (IC50 = 26.60 µM). None of the isolated compounds inhibited ABCB1 efflux pump (EP; P-glycoprotein) or the bacterial EPs.Acetoxydihydrodamsin, 1'-noraltamisin, and psilostachyin showed the most remarkable cytotoxic and antiproliferative activity on tumour cell lines and exerted selectivity towards MRC-5 cell line.},
	keywords = {ASTERACEAE; RAGWEED; 1,10-dihydro-1′-noraltamisin; human colonic},
	year = {2022},
	eissn = {1744-5116},
	pages = {1511-1519},
	orcid-numbers = {Kúsz, Norbert/0000-0002-9973-6442; Kiss, Tivadar/0000-0003-3538-377X; Rácz, Bálint/0000-0003-0088-3408; Spengler, Gabriella/0000-0001-8085-0950; Csupor, Dezső/0000-0002-4088-3333}
}

@article{MTMT:32948511,
	title = {A comprehensive phytochemical and pharmacological review on sesquiterpenes from the genus Ambrosia},
	url = {https://m2.mtmt.hu/api/publication/32948511},
	author = {Kovács, Balázs and Hohmann, Judit and Csupor-Löffler, Boglárka and Kiss, Tivadar and Csupor, Dezső},
	doi = {10.1016/j.heliyon.2022.e09884},
	journal-iso = {HELIYON},
	journal = {HELIYON},
	volume = {8},
	unique-id = {32948511},
	year = {2022},
	eissn = {2405-8440},
	orcid-numbers = {Hohmann, Judit/0000-0002-2887-6392; Kiss, Tivadar/0000-0003-3538-377X; Csupor, Dezső/0000-0002-4088-3333}
}

@CONFERENCE{MTMT:32013398,
	title = {Cytotoxic and antiproliferative activity of sesquiterpene lactones isolated from the aerial parts of Ambrosia artemisiifolia},
	url = {https://m2.mtmt.hu/api/publication/32013398},
	author = {Kovács, Balázs},
	booktitle = {2nd Symposium of Young Researchers on Pharmacognosy},
	doi = {10.14232/syrpharmacognosy.2021.a13},
	unique-id = {32013398},
	year = {2021}
}

@{MTMT:30718576,
	title = {Isolation of sesquiterpene lactones from common ragweed (Ambrosia artemisiifolia L.)},
	url = {https://m2.mtmt.hu/api/publication/30718576},
	author = {Kovács, Balázs and Kiss, Tivadar and Csupor-Löffler, Boglárka and Ferencz, Elek and Kúsz, Norbert and Tsai, Yu-Chi and Hohmann, Judit and Csupor, Dezső},
	booktitle = {Trends in Natural Product Research - PSE Young Scientists’ Meeting on Biochemistry, Molecular Aspects and Pharmacology of Bioactive Natural Products},
	doi = {10.14232/tnpr.2019.po21},
	unique-id = {30718576},
	abstract = {Common ragweed (Ambrosia artemisiifolia L., Asteraceae) is an invasive species in Europe with allergic pollens. Ragweed originates from North America, but it also occurs and is spreading in Europe, due to the plant’s successful reproductive potential and a strong allelopathic effects against the native flora. Some of the plant’s secondary metabolites, called sesquiterpene lactones possess allergic, allopathic, anti-inflammatory, antitumor, antimicrobial activity. In a phytochemical view the plant secondary metabolites have not explored completely. The aim of our study was to isolate the major phytochemicals from the aerial parts of Ambrosia artemisiifolia, especially focusing on the sesquiterpene lactone compounds, and elucidate their chemical structure. The methanolic extract of the plant was separated by several chromatographic techniques, including preparative TLC and HPLC analysis. One new and six known sesquiterpene lactones were isolated from the aerial parts of ragweed. Their structure was identified by 1H NMR, 13C NMR and mass spectroscopy. 1’-Noraltamisin, a seco-pseudoguaianolide was reported for the first time from this plant. Further investigation needed to identify the biological activities and molecular mechanisms of the isolated compounds, particularly the new seco-pseudoguaianolide.},
	year = {2019},
	pages = {103-103},
	orcid-numbers = {Kiss, Tivadar/0000-0003-3538-377X; Kúsz, Norbert/0000-0002-9973-6442; Hohmann, Judit/0000-0002-2887-6392; Csupor, Dezső/0000-0002-4088-3333}
}

@article{MTMT:3293257,
	title = {COMPARATIVE STUDY ON GROWTH AND PHOTOSYNTHETIC PIGMENT DYNAMICS OF TWO MICROALGAE UNDER THE INFLUENCE OF WATER POLLUTION WITH THE HERBICIDE GLUFOSINATE},
	url = {https://m2.mtmt.hu/api/publication/3293257},
	author = {SEBASTIAN, RADU CRISTIAN PLUGARU and LASZLO, FODORPATAKI and MIHAELA, ORBAN and ANCA, SARB and Tompa, Bernát and Kovács, Balázs},
	doi = {10.24193/subbchem.2017.3.20},
	journal-iso = {STUD UNIV BABES-BOLYAI CHEM},
	journal = {STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA},
	volume = {62},
	unique-id = {3293257},
	issn = {1224-7154},
	year = {2017},
	eissn = {2065-9520},
	pages = {239-250}
}

@article{MTMT:3290159,
	title = {PHYSIOLOGICAL MARKERS OF DUCKWEED (Lemna minor L.) FOR BIOINDICATION OF WATER POLLUTION WITH COPPER AND DIURON (3-(3,4-DICHLOROPHENYL)-1,1-DIMETHYLUREA)},
	url = {https://m2.mtmt.hu/api/publication/3290159},
	author = {Laszlo, FODORPATAKI and Szabolcs, BARNA and Hilda, DEAK and Kovács, Balázs and Janos, GERAJ and Botond, HOLINKA},
	journal-iso = {AN U O FASC BIOL},
	journal = {ANALELE UNIVERSITATII DIN ORADEA FASCICULA DE BIOLOGIE},
	volume = {21},
	unique-id = {3290159},
	issn = {1224-5119},
	year = {2014},
	eissn = {1844-7589},
	pages = {19-23}
}