TY - JOUR AU - Bakacsy, László AU - Kardos, Luca Viktória AU - Szepesi, Ágnes AU - Nagy, Krisztina Napsugár AU - Vasas, Andrea AU - Feigl, Gábor TI - Investigation of the Allelopathic Effect of Two Invasive Plant Species in Rhizotron System JF - LIFE-BASEL J2 - LIFE-BASEL VL - 14 PY - 2024 IS - 4 PG - 15 SN - 2075-1729 DO - 10.3390/life14040475 UR - https://m2.mtmt.hu/api/publication/34771221 ID - 34771221 AB - A key question in plant invasion biology is why invasive plants are more competitive in their introduced habitat than in their native habitat. Studies show that invasive species exhibit allelopathy, influencing other plants by releasing chemicals. Research on allelopathy uses in vitro tests, investigating effects on seed germination and seedling development. Although soil plays a role in modifying allelopathic effects, observations with soil are rare and almost nothing is known about the root development of test plants developing in soil and the effects of allelopathic compounds on root architecture. Our study evaluates the allelopathic effects of false indigo-bush (Amorpha fruticosa L.) and common milkweed (Asclepias syriaca L.) on oilseed rape growth as a model plant. The rhizotron system was used to study the effect of morphology and root architecture. Leaf–soil mixtures at 0.5%, 1%, and 5% concentrations were used. Shoot and root development was strongly inhibited at 5%. But there was no difference between the allelopathy of the two species, and the application of lower concentrations did not show any effect, demonstrating that soil has a significant modifying effect on their allelopathy. Our results highlight that the development of roots growing in the soil is also worth investigating in connection with allelopathy, which can strengthen the ecological importance of allelochemicals during successful invasions. LA - English DB - MTMT ER - TY - CONF AU - Barta, Anita AU - Petz, Petra AU - Stefkó, Dóra AU - Purger, Dragica AU - Bakacsy, László AU - Hohmann, Judit AU - Vasas, Andrea ED - Hohmann, Judit TI - Isolation and structure determination of compounds from Juncus species T2 - 4th Symposium of Young Researchers on Pharmacognosy PB - Institute of Pharmacognosy, Faculty of Pharmacy, University of Szeged C1 - Szeged PY - 2023 SP - 9 EP - 9 PG - 1 DO - 10.14232/syrmpnpr.2023.3 UR - https://m2.mtmt.hu/api/publication/33963376 ID - 33963376 LA - English DB - MTMT ER - TY - CONF AU - Dávid, Csilla Zsuzsanna AU - Juhász, András AU - Kúsz, Norbert AU - Hohmann, Judit AU - Vasas, Andrea ED - Hohmann, Judit TI - Phytochemical investigation of a Hungarian sedge, Carex morrowii T2 - 4th Symposium of Young Researchers on Pharmacognosy PB - Institute of Pharmacognosy, Faculty of Pharmacy, University of Szeged C1 - Szeged PY - 2023 SP - 11 EP - 11 PG - 1 DO - 10.14232/syrmpnpr.2023.5 UR - https://m2.mtmt.hu/api/publication/33963414 ID - 33963414 LA - English DB - MTMT ER - TY - JOUR AU - Kovács, Tibor AU - Lajter, Ildikó AU - Kúsz, Norbert AU - Schelz, Zsuzsanna AU - Bózsity-Faragó, Noémi AU - Borbás, Anikó AU - Zupkó, István AU - Krupitza, Georg AU - Frisch, Richard AU - Hohmann, Judit AU - Vasas, Andrea AU - Mándi, Attila TI - Isolation and NMR Scaling Factors for the Structure Determination of Lobatolide H, a Flexible Sesquiterpene from Neurolaena lobata JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 24 PY - 2023 IS - 6 PG - 19 SN - 1661-6596 DO - 10.3390/ijms24065841 UR - https://m2.mtmt.hu/api/publication/33708328 ID - 33708328 AB - A new flexible germacranolide (1, lobatolide H) was isolated from the aerial parts of Neurolaena lobata. The structure elucidation was performed by classical NMR experiments and DFT NMR calculations. Altogether, 80 theoretical level combinations with existing 13C NMR scaling factors were tested, and the best performing ones were applied on 1. 1H and 13C NMR scaling factors were also developed for two combinations utilizing known exomethylene containing derivatives, and the results were complemented by homonuclear coupling constant (JHH) and TDDFT-ECD calculations to elucidate the stereochemistry of 1. Lobatolide H possessed remarkable antiproliferative activity against human cervical tumor cell lines with different HPV status (SiHa and C33A), induced cell cycle disturbance and exhibited a substantial antimigratory effect in SiHa cells. LA - English DB - MTMT ER - TY - BOOK ED - Vasas, Andrea TI - Új Nemzeti Kiválósági Program. Az SZTE Gyógyszerésztudományi Kar 2022. évi ÚNKP díjazottjainak tudományos előadóülése TS - Az SZTE Gyógyszerésztudományi Kar 2022. évi ÚNKP díjazottjainak tudományos előadóülése PB - Szegedi Tudományegyetem, Gyógyszerésztudományi Kar C1 - Szeged PY - 2023 SP - 28 UR - https://m2.mtmt.hu/api/publication/34041288 ID - 34041288 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Bakacsy, László AU - Sípos, Lilla AU - Barta, Anita AU - Stefkó, Dóra AU - Vasas, Andrea AU - Szepesi, Ágnes TI - Concentration-dependent effects of effusol and juncusol from Juncus compressus on seedling development of Arabidopsis thaliana JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 12 PY - 2022 IS - 1 PG - 12 SN - 2045-2322 DO - 10.1038/s41598-022-18063-5 UR - https://m2.mtmt.hu/api/publication/33053853 ID - 33053853 N1 - Department of Plant Biology, Institute of Biology, Faculty of Science and Informatics, University of Szeged, Közép Fasor 52., Szeged, 6726, Hungary Department of Pharmacognosy, Faculty of Pharmacy, University of Szeged, Eötvös u. 6, Szeged, 6720, Hungary Cited By :2 Export Date: 14 November 2023 Correspondence Address: Szepesi, Á.; Department of Plant Biology, Közép Fasor 52., Hungary; email: szepesia@bio.u-szeged.hu Chemicals/CAS: effusol; juncusol; Phenanthrenes; Polyamines Funding details: FK129061, NTP-NFTÖ-19-B-0208 Funding details: 5395 Funding details: Emberi Eroforrások Minisztériuma, EMMI, OTKA K 128963 Funding details: Nemzeti Kutatási Fejlesztési és Innovációs Hivatal, NKFIH Funding text 1: The authors thank Réka Szőllősi for help with the statistical analysis. This work was conducted with the financial support of NKFIH OTKA Grant FK129061, Grant NTP-NFTÖ-19-B-0208 from the Ministry of Human Capacities, and partly from Grant OTKA K 128963 from NKFIH. The publication was financed by the University of Szeged Open Access Fund, Grant No. 5395. AB - Juncus species are valuable sources of phenanthrene compounds that have been used in traditional Chinese medicine for thousands of years. Effusol and juncusol are the most investigated compounds reported to have antimicrobial and anticancer effects; however, to date, their effects on higher plants have not been investigated. In this study, we examined the effects of effusol and juncusol on the growth and other biochemical parameters of the dicot model plant Arabidopsis thaliana in a concentration-dependent manner with a focus on polyamine metabolism. Phenanthrene induced toxic effects on plant growth and development, while effusol and juncusol induced higher biomass and maintained antioxidant defence mechanisms associated with reduced polyamine degradation. Taken together, our results suggest that these compounds could be good candidates for new biopesticide or biostimulant plant growth regulators in the future. LA - English DB - MTMT ER - TY - JOUR AU - Barta, Anita AU - Körmöczi, Tímea AU - Bús, Csaba AU - Stefkó, Dóra AU - Hohmann, Judit AU - Vasas, Andrea AU - Berkecz, Róbert TI - Targeted liquid chromatography-quadrupole Orbitrap mass spectrometry method for the quantification of phenanthrenes in Juncus compressus Jacq JF - PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH J2 - PLANTA MED VL - 88 PY - 2022 IS - 15 SP - 1525 SN - 0032-0943 DO - 10.1055/s-0042-1759219 UR - https://m2.mtmt.hu/api/publication/33575918 ID - 33575918 LA - English DB - MTMT ER - TY - CHAP AU - Bús, Csaba AU - Z., Kása AU - Vasas, Andrea AU - P., Sipos ED - P., Segľa ED - J., Pavlik ED - J., Švorec ED - M., Piroš ED - F., Jozefíková TI - Preparation of oxidised phenanthrenoid derivatives with increased antiproliferative activity on human adherent cell lines T2 - Recent Progress in Coordination, Bioinorganic and Applied Inorganic Chemistry PB - Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava CY - Smolenice SN - 9788082080806 PY - 2022 SP - 31 PG - 1 UR - https://m2.mtmt.hu/api/publication/33140253 ID - 33140253 LA - English DB - MTMT ER - TY - JOUR AU - Dávid, Csilla Zsuzsanna AU - Kúsz, Norbert AU - Pinke, Gyula AU - Kulmány, Ágnes Erika AU - Zupkó, István AU - Hohmann, Judit AU - Vasas, Andrea TI - Jacaranone Derivatives with Antiproliferative Activity from Crepis pulchra and Relevance of This Group of Plant Metabolites JF - PLANTS-BASEL J2 - PLANTS-BASEL VL - 11 PY - 2022 IS - 6 PG - 11 SN - 2223-7747 DO - 10.3390/plants11060782 UR - https://m2.mtmt.hu/api/publication/32779416 ID - 32779416 LA - English DB - MTMT ER - TY - JOUR AU - Dávid, Csilla Zsuzsanna AU - Kúsz, Norbert AU - Stefkó, Dóra AU - Papp, L AU - Hohmann, Judit AU - Vasas, Andrea TI - Screening of the antioxidant capacity of Cyperaceae species and isolation of stilbenoids and other phenolic compounds from Carex praecox JF - PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH J2 - PLANTA MED VL - 88 PY - 2022 IS - 15 SP - 1542 SN - 0032-0943 DO - 10.1055/s-0042-1759267 UR - https://m2.mtmt.hu/api/publication/33686911 ID - 33686911 LA - English DB - MTMT ER -