@article{MTMT:36924561,
	title = {Preparation of Ester-Crosslinked PI Membranes with Enhanced Gas Selectivity and Plasticization Resistance},
	url = {https://m2.mtmt.hu/api/publication/36924561},
	author = {Li, Yu and Luo, Jiangzhou and Ling, Honglei and Xue, Song},
	doi = {10.3390/membranes16010047},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {16},
	unique-id = {36924561},
	abstract = {Fabricating polyimide (PI) membranes with outstanding anti-plasticization ability and gas separation performance remains a challenge. In this study, two novel diamine monomers, DAMBO (methyl 3,5-diamino-4-methylbenzoate) and DAPGBO (3-hydroxypropyl 3,5-diamino-4-methylbenzoate), were synthesized through esterification reactions. Then, we copolymerized each of these two new monomers with 4,4′-diaminodiphenylmethane (DAM) and 4,4′-(Hexafluoroisopropylidene) diphthalic anhydride (6FDA) separately to yield two monoesterified PIs. Following this, we further prepared the ester-crosslinked PIs by inducing a transesterification crosslinking reaction within the PI-PGBO membrane via thermal treatment. As expected, we found that the formation of cross-linked structures can effectively regulate the microporous structure, enhance its sieving performance, and thus improve the membrane’s gas selectivity. Furthermore, the resulting network structure endowed the thermally treated PI membrane with excellent anti-plasticization ability. Physical characterization results show that after heat treatment, both the d-spacing and BET surface area of the PI membrane decreased, but the solvent resistance of the thermally treated PIs was significantly improved. Gas separation experiments revealed that the representative membrane (PI-PGBO-300) exhibited the optimal CO2/CH4 separation performance, with a CO2 permeability of 371.05 Barrer, a CO2/CH4 selectivity of 28.11, and a CO2 plasticization pressure exceeding 30 bar. This study provides valuable insights into the design of cross-linked polyimides (PIs) via transesterification reactions, which are capable of enhancing the performance of membrane-based gas separation processes.},
	year = {2026},
	eissn = {2077-0375},
	orcid-numbers = {Ling, Honglei/0000-0003-1836-3777}
}

@article{MTMT:36325330,
	title = {Mitochondria-Associated Membrane Dysfunction in Neurodegeneration and Its Effects on Lipid Metabolism, Calcium Signaling, and Cell Fate},
	url = {https://m2.mtmt.hu/api/publication/36325330},
	author = {Truong, Thi Thuy and Singh, Alka Ashok and Bang, Nguyen Van and Vu, Nguyen Minh Hung and Na, Sungsoo and Choi, Jaeyeop and Oh, Junghwan and Mondal, Sudip},
	doi = {10.3390/membranes15090263},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {15},
	unique-id = {36325330},
	abstract = {Mitochondria-associated membranes (MAMs) are essential for cellular homeostasis. MAMs are specialized contact sites located between the endoplasmic reticulum (ER) and mitochondria and control apoptotic pathways, lipid metabolism, autophagy initiation, and calcium signaling, processes critical to the survival and function of neurons. Although this area of membrane biology remains understudied, increasing evidence links MAM dysfunction to the etiology of major neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). MAMs consist of a network of protein complexes that mediate molecular exchange and ER–mitochondria tethering. MAMs regulate lipid flow in the brain, including phosphatidylserine and cholesterol; disruption of this process causes membrane instability and impaired synaptic function. Inositol 1,4,5-trisphosphate receptor—voltage-dependent anion channel 1 (IP3R-VDAC1) interactions at MAMs maintain calcium homeostasis, which is required for mitochondria to produce ATP; dysregulation promotes oxidative stress and neuronal death. An effective therapeutic approach for altering neurodegenerative processes is to restore the functional integrity of MAMs. Improving cell-to-cell interactions and modulating MAM-associated proteins may contribute to the restoration of calcium homeostasis and lipid metabolism, both of which are key for neuronal protection. MAMs significantly contribute to the progression of neurodegenerative diseases, making them promising targets for future therapeutic research. This review emphasizes the increasing importance of MAMs in the study of neurodegeneration and their potential as novel targets for membrane-based therapeutic interventions.},
	year = {2025},
	eissn = {2077-0375},
	pages = {263},
	orcid-numbers = {Singh, Alka Ashok/0000-0003-4049-102X; Vu, Nguyen Minh Hung/0009-0008-3009-0939; Na, Sungsoo/0000-0002-4425-8906; Oh, Junghwan/0000-0002-5837-0958; Mondal, Sudip/0000-0002-0638-9657}
}

@article{MTMT:36342591,
	title = {Fluorine-Free Membranes Consisting of a Blend of S-PVA and PEBAX 1657 for Proton Exchange Membrane Fuel Cells: The Role of Titanium Dioxide Phosphate (TiO2PO4) Nanoparticle Fillers},
	url = {https://m2.mtmt.hu/api/publication/36342591},
	author = {Al- Mashhadani, Manhal Hameed Ibrahim and Szijjártó, Gábor and Selim, Asmaa Khaled Mohamed and Sebestyén, Zoltán and Mihály, Judith and Tompos, András},
	doi = {10.3390/membranes15090280},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {15},
	unique-id = {36342591},
	abstract = {Novel blend membranes containing S-PVA and PEBAX 1657 at a blend ratio of 8:2 were doped with varying amounts of titanium dioxide phosphate (TiO2PO4) as a nanoparticle filler at concentrations of 0, 3, 5, and 7 wt%. The membranes were fabricated using the solution-casting technique. The effect of the TiO2PO4 nanofiller on the polymer matrix was thoroughly investigated. Our aim was to investigate how the incorporation of TiO2PO4 nanofillers into non-fluorinated SPP-based membranes affects their structural, physicochemical, and electrochemical properties for application in fuel cells. Crystallinity of the samples was checked by means of X-ray diffraction (XRD), while FTIR was used to investigate the contact between the nanofiller and the polymers. The good compatibility resulted in strong interactions between the constituents and led to increased crystallinity of the membrane as well. Furthermore, SEM images confirmed the uniform distribution of the nanofiller. These structural features led to good thermal stability, as evidenced by thermogravimetric analysis (TGA), and good mechanical strength, as proved by tensile tests. Among the samples investigated, the highest water uptake of 51.70% was achieved on the composite membrane containing 3 wt% TiO2PO4, which also showed the highest ion exchange capacity at room temperature, reaching 1.13 meq/g. In line with these properties, among the synthesized membranes, the membrane labeled SPP 3% TiO2PO4 has the highest current density and power density, with values of 175.5 mA/cm2 and 61.52 mW/cm2, respectively.},
	year = {2025},
	eissn = {2077-0375}
}

@article{MTMT:36385129,
	title = {Lipid Raft Membrane Interactivity Correlating with Cyclooxygenase-2 Selectivity of Non-Steroidal Anti-Inflammatory Drugs},
	url = {https://m2.mtmt.hu/api/publication/36385129},
	author = {Mizogami, Maki and Iida, Hiroki and Tsuchiya, Hironori},
	doi = {10.3390/membranes15090284},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {15},
	unique-id = {36385129},
	abstract = {The primary mechanism of non-steroidal anti-inflammatory drugs (NSAIDs) is inhibition of prostaglandin production mediated by cyclooxygenase. Given the possible association of cyclooxygenase-2, but not cyclooxygenase-1, with membrane lipid rafts, we assessed whether the lipid raft membrane interactivity of NSAIDs correlates with cyclooxygenase-2 selectivity. Lipid raft model membranes and reference membranes were prepared with 1,2-dioleoylphosphatidylcholine/sphingomyelin/cholesterol and 1,2-dipalmitoylphosphatidylcholine, respectively. After treating the membranes with 2–50 μM NSAIDs at pH 7.4, 6.5, and 5.5, fluorescence polarization was measured to determine their membrane interactivity. Conventional NSAIDs (diclofenac, ibuprofen, indomethacin, aspirin, and flurbiprofen) and Coxibs (lumiracoxib, etoricoxib, celecoxib, valdecoxib, and rofecoxib) decreased membrane fluidity, whereas Oxicams (meloxicam, piroxicam, tenoxicam, and lornoxicam) increased. Membrane effects of NSAIDs were so dependent on medium pH that they significantly increased with reducing pH from 7.4 to 5.5. Under inflammatory acidic conditions, the lipid raft membrane interactivity of NSAIDs was more likely to correlate with cyclooxygenase-2 selectivity than the reference membrane interactivity. It is hypothesized that NSAIDs may interact with lipid raft membranes to induce membrane fluidity changes with the potency corresponding to cyclooxygenase-2 inhibition, disrupting the structural and functional integrity of lipid rafts to affect the activity of cyclooxygenase-2 localized in lipid rafts, resulting in cyclooxygenase-2 selective inhibition.},
	year = {2025},
	eissn = {2077-0375},
	orcid-numbers = {Tsuchiya, Hironori/0000-0002-0244-6407}
}

@article{MTMT:36408491,
	title = {A Validated CFD Model for Gas Exchange in Hollow Fiber Membrane Oxygenators: Incorporating the Bohr and Haldane Effects},
	url = {https://m2.mtmt.hu/api/publication/36408491},
	author = {Monsefi, Estakhrposhti Seyyed Hossein and Xu, Jingjing and Gfoehler, Margit and Harasek, Michael},
	doi = {10.3390/membranes15090268},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {15},
	unique-id = {36408491},
	abstract = {Chronic respiratory diseases claim nearly four million lives annually, making them the third leading cause of death worldwide. Extracorporeal membrane oxygenation (ECMO) is often the last line of support for patients with severe lung failure. Still, its performance is limited by an incomplete understanding of gas exchange in hollow fiber membrane (HFM) oxygenators. Computational fluid dynamics (CFD) has become a robust oxygenator design and optimization tool. However, most models oversimplify O2 and CO2 transport by ignoring their physiological coupling, instead relying on fixed saturation curves or constant-content assumptions. For the first time, this study introduces a novel physiologically informed CFD model that integrates the Bohr and Haldane effects to capture the coupled transport of oxygen and carbon dioxide as functions of local pH, temperature, and gas partial pressures. The model is validated against in vitro experimental data from the literature and assessed against established CFD models. The proposed CFD model achieved excellent agreement with experiments across blood flow rates (100-500 mL/min ), with relative errors below 5% for oxygen and 10-15% for carbon dioxide transfer. These results surpassed the accuracy of all existing CFD approaches, demonstrating that a carefully formulated single-phase model combined with physiologically informed diffusivities can outperform more complex multiphase simulations. This work provides a computationally efficient and physiologically realistic framework for oxygenator optimization, potentially accelerating device development, reducing reliance on costly in vitro testing, and enabling patient-specific simulations.},
	keywords = {Chemistry, Physical; gas exchange; computational fluid dynamics (CFD); Biochemistry & Molecular Biology; Materials Science, Multidisciplinary; Engineering, Chemical; Bohr and Haldane effects; physiological coupling},
	year = {2025},
	eissn = {2077-0375}
}

@article{MTMT:36645610,
	title = {Recent Progress on the Development of Polyetheretherketone Membranes for Water Remediation},
	url = {https://m2.mtmt.hu/api/publication/36645610},
	author = {Zhou, Jingwen and Wang, Longjun and Liu, Hong and Li, Xinhao and Li, Dalong and Yan, Linlin and Cheng, Xiquan},
	doi = {10.3390/membranes15090256},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {15},
	unique-id = {36645610},
	keywords = {PEEK; Membrane preparation; hydrophilic modifications; water remediation applications},
	year = {2025},
	eissn = {2077-0375},
	orcid-numbers = {Li, Dalong/0000-0002-6953-150X}
}

@article{MTMT:36281362,
	title = {Advanced Materials-Based Nanofiltration Membranes for Efficient Removal of Organic Micropollutants in Water and Wastewater Treatment},
	url = {https://m2.mtmt.hu/api/publication/36281362},
	author = {Wei, Haochun and Nong, Haibiao and Chen, Li and Zhang, Shiyu},
	doi = {10.3390/membranes15080236},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {15},
	unique-id = {36281362},
	abstract = {The increasing use of pharmaceutically active compounds (PhACs), endocrine-disrupting compounds (EDCs), and personal care products (PCPs) has led to the widespread presence of organic micropollutants (OMPs) in aquatic environments, posing a significant global challenge for environmental conservation. In recent years, advanced materials-based nanofiltration (NF) technologies have emerged as a promising solution for water and wastewater treatment. This review begins by examining the sources of OMPs, as well as the risk of OMPs. Subsequently, the key criteria of NF membranes for OMPs are discussed, with a focus on the roles of pore size, charge property, molecular interaction, and hydrophilicity in the separation performance. Against that background, this review summarizes and analyzes recent advancements in materials such as metal organic frameworks (MOFs), covalent organic frameworks (COFs), graphene oxide (GO), MXenes, hybrid materials, and environmentally friendly materials. It highlights the porous nature and structural diversity of organic framework materials, the advantage of inorganic layered materials in forming controllable nanochannels through stacking, the synergistic effects of hybrid materials, and the importance of green materials. Finally, the challenges related to the performance optimization, scalable fabrication, environmental sustainability, and complex separation of advanced materials-based membranes for OMP removal are discussed, along with future research directions and potential breakthroughs.},
	year = {2025},
	eissn = {2077-0375},
	pages = {236},
	orcid-numbers = {Chen, Li/0009-0003-2773-2949; Zhang, Shiyu/0009-0008-5766-6061}
}

@article{MTMT:36282471,
	title = {Treatment of Dairy Wastewater Retentate After Microfiltration: Evaluation of the Performance of the System Based on Activated Sludge and Activated Carbon},
	url = {https://m2.mtmt.hu/api/publication/36282471},
	author = {Życki, Maciej and Barszcz, Wioletta and Łożyńska, Monika},
	doi = {10.3390/membranes15080237},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {15},
	unique-id = {36282471},
	abstract = {The dairy industry generates significant amounts of wastewater, including microfiltration (MF) retentate, a byproduct thickened with organic and inorganic pollutants. This study focuses on the treatment of two times concentrated MF retentate using a hybrid system based on biological treatment in a sequential batch reactor (SBR) and adsorption on activated carbon. The first stage involved cross-flow microfiltration using a 0.2 µm PVDF membrane at 0.5 bar, resulting in reductions of 99% in turbidity and 79% in chemical oxygen demand (COD), as well as a partial reduction in conductivity. The second stage involved 24-h biological treatment in a sequential batch reactor (SBR) with activated sludge (activated sludge index: 80 cm3/g, MLSS 2500 mg/dm3), resulting in further reductions in COD (62%) and TOC (30%), as well as the removal of 46% of total phosphorus (TP) and 35% of total nitrogen (TN). In the third stage, the decantate underwent adsorption in a column containing powdered activated carbon (PAC; 1 g; S_(BET) = 969 m2 g−1), reducing the concentrations of key indicators to the following levels: COD 84%, TOC 70%, TN 77%, TP 87% and suspended solids 97%. Total pollutant retention ranged from 24.6% to 97.0%. These results confirm that the MF–SBR–PAC system is an effective, compact solution that significantly reduces the load of organic and biogenic pollutants in MF retentates, paving the way for their reuse or safe discharge into the environment.},
	year = {2025},
	eissn = {2077-0375},
	pages = {237},
	orcid-numbers = {Życki, Maciej/0000-0001-7361-0932; Barszcz, Wioletta/0000-0003-1182-5983; Łożyńska, Monika/0000-0002-3789-7531}
}

@article{MTMT:36568082,
	title = {Review of Hollow Fiber Membranes for Gas Separation: Exploring Fundamentals and Recent Advancements},
	url = {https://m2.mtmt.hu/api/publication/36568082},
	author = {Grosso, Valentina and Rizzuto, Carmen and Tocci, Elena and Fuoco, Alessio and Longo, Mariagiulia and Monteleone, Marcello and Hajivand, Pegah and Jansen, Johannes C. and Esposito, Elisa},
	doi = {10.3390/membranes15080246},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {15},
	unique-id = {36568082},
	keywords = {Gas separation; hollow fiber membrane; Membrane material; application of hollow fibers},
	year = {2025},
	eissn = {2077-0375}
}

@article{MTMT:36696260,
	title = {Recent Developments in Polymer Inclusion Membranes: Advances in Selectivity, Structural Integrity, Environmental Applications and Sustainable Fabrication},
	url = {https://m2.mtmt.hu/api/publication/36696260},
	author = {Nowik-Zajac, Anna and Sabadash, Vira},
	doi = {10.3390/membranes15080249},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {15},
	unique-id = {36696260},
	keywords = {ionic liquids; Gas separation; Membrane stability; heavy metal removal; POLYMER INCLUSION MEMBRANES; deep eutectic solvents; CARRIER-MEDIATED TRANSPORT; green membrane technologies; analytical sensing membranes; sustainable separation processes},
	year = {2025},
	eissn = {2077-0375},
	orcid-numbers = {Sabadash, Vira/0000-0002-6091-4053}
}