https://m2.mtmt.hu/ hun 2026-10-24 04:52 JournalArticle 37108844 VALIDATED true 0 false 2026-09-13T21:01:48.534+0000 2026-09-09T11:02:15.142+0000 2026-05-05T08:16:46.670+0000 true 10097128 Sass Dávid /api/admin/10097128 Admin true 2026-09-09T11:02:14.882+0000 2026-07-03T10:41:28.318+0000 true 10097129 Vékony-Pap Lili /api/admin/10097129 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Bortnikov, Evgeniy O Designing soft materials through synthetic morphogenesis true true /api/journal/10015678 REVIEWED true false 10015678 false 10015678 true 2041-1723 Journal FOREIGN 17 1 5494 5494 11 2026 While the principles of Turing-type morphogenesis are central to understanding biological pattern formation, their rational application for the design of synthetic materials remains a significant challenge. To address this gap, we rationally design stationary reaction-diffusion patterns using a chemical reaction network (CRN) of small organic molecules bearing thiol groups - a functional handle ubiquitous in materials chemistry. The CRN features autocatalysis coupled with both rapid direct inhibition and a negative feedback loop. We report the formation of dot, line, and net patterns obtained with the assistance of numerical modeling by adjusting reactant feed rates and concentrations. The use of disulfide-crosslinked polyacrylamide hydrogels enables the modulation of thiol diffusion and subsequent derivatization of the immobilized thiols with dyes, enzymes, and crosslinkers to produce soft materials. This entire process, from out-of-equilibrium self-organization to a patterned soft material, conceptually resembles the biological process that gives rise to skin patterns. Overall, this work establishes a pathway for applying Turing-type self-organization to the structuring of synthetic matter. © 2026. 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TTIK / KI); Fizikai Kémiai és Anyagtudományi Tanszék (SZTE / TTIK / KI) 3 11 2 13 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 137749194 /api/authorship/137749194 1 0.07692308 true false false Bortnikov Evgeniy O true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 137749195 /api/authorship/137749195 2 0.07692308 false false false Paikar Arpita true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 137749196 /api/authorship/137749196 3 0.07692308 false false false Zhigileva Ekaterina A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 137749197 /api/authorship/137749197 4 0.07692308 false false false Fomitskaya Polina true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 137749198 /api/authorship/137749198 5 0.07692308 false false false Ariel Noam true false false 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/api/mtarating/11551153 RatingType 10010 /api/ratingtype/10010 RegTB Institute 14100 /api/institute/14100 0 false true false Regionális Tudományok Bizottsága Committee on Regional Studies true 14100 true true true A nemzetközi false true SjrRating 11668532 /api/sjrrating/11668532 10 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1301 /api/classificationexternal/1301 true 1301 true D1 FROM_LAST_YEAR true true /api/publication/37108844 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Bortnikov Evgeniy O </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Paikar Arpita </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Zhigileva Ekaterina A </span> 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