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      <abstractText>To create an algorithm to detect rheoencephalographic (REG) pulse wave second peak increase, which may detect an increase in intracranial pressure (ICP). REG was measured in 19 healthy volunteers during control and a 15-degree head-down tilt (HDT), which caused an increase in ICP. We developed an algorithm for automatically calculating P1 and P2 from the REG pulse waveform. The result was compared to manual measurements during control and HDT positions. The automatic determination of the peaks’ time instants was considered a series of two-class decision problems in ±15-ms-wide sliding decision windows. We achieved an accuracy of 0.9826, a sensitivity of 0.7727, and a specificity of 0.9902. We used the correlation coefficient between manual measurements and automated data and the normalized mean absolute error (NMAE) metric to characterize the precision of peak amplitude value estimation. We achieved a high correlation (> 0.8) in 92% of all tests, and NMAE &lt; 0.3 in 96%. The remaining cases were analyzed using Bland-Altman plots to uncover the main causes of differences. We tested the hypothesis of increasing P2 peak amplitude during HDT compared to the control position. In the female group, the number of significant increases was 4 out of 6 (67%), both in manual and automatic measurements. In the case of the male group’s manual measurements, 12 of 13 (92%), and the automatic calculation gave 10 of 13 (77%). The significance is to switch from invasive ICP to noninvasive REG to have the same information for decision-making at the bedside to save the lives of neurocritical care patients. Future REG correlation studies suggested using REG in neurocritical care monitoring, space research, and military medical practice.</abstractText>
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      <label>Pinter Istvan et al. Automatic Calculation of the Rheoencephalographic Pulse Wave Peaks: The First Results. (2026) International Journal of Methodology 1 1-15</label><template>&lt;div class=&quot;JournalArticle Publication short-list&quot;&gt; &lt;div class=&quot;authors&quot;&gt; &lt;span class=&quot;author-name&quot; mtid=&quot;10013215&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10013215&quot; target=&quot;_blank&quot;&gt;Pinter, Istvan&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; &gt; Bagany, Mihaly &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10022416&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10022416&quot; target=&quot;_blank&quot;&gt;Szabo, Sandor&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; &gt; Bodo, Michael &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; &lt;/div &gt;&lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;36935295&quot; 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