https://m2.mtmt.hu/ hun 2026-09-22 09:32 JournalArticle 36849434 VALIDATED true 0 false 2026-05-17T21:08:20.355+0000 2026-02-04T11:19:36.223+0000 2026-01-06T12:44:59.274+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2026-02-04T11:19:36.333+0000 2026-02-04T11:19:36.333+0000 2026-01-06T12:48:56.620+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true Admin 10073918 /api/admin/10073918 Kovács Marcell true true 2026-01-26T16:13:41.604+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Bartek, Virag Associations Between Fetal Symptoms During Pregnancy and Neonatal Clinical Complications with Cytomegalovirus Infection true true /api/journal/10071196 REVIEWED true false 10071196 false 10071196 true 2227-9067 Journal FOREIGN 12 12 1690 1690 15 2025 Highlights What are the main findings? In cases of recent Cytomegalovirus infection, the most common ultrasound abnormality affects the gastrointestinal and nervous system. Based on the neonatological follow-up examinations, 15.52% newborns had complications. What are the implications of the main findings? Accurate knowledge of the rate of ultrasound abnormalities is important for prenatal diagnosis. Amniotic fluid CMV PCR yields valuable information about CMV transmission, supporting decisions in newborn care.Highlights What are the main findings? In cases of recent Cytomegalovirus infection, the most common ultrasound abnormality affects the gastrointestinal and nervous system. Based on the neonatological follow-up examinations, 15.52% newborns had complications. What are the implications of the main findings? Accurate knowledge of the rate of ultrasound abnormalities is important for prenatal diagnosis. Amniotic fluid CMV PCR yields valuable information about CMV transmission, supporting decisions in newborn care.Abstract Introduction: Primary Cytomegalovirus (CMV) infection occurs in 0.7-4.1% of all pregnancies. Our study aims to analyze the incidence rate of ultrasound anomalies, as well as CMV PCR analysis of the amniotic fluid sample obtained from amniocentesis in CMV-infected pregnancies, as well as the outcome of the pregnancies and neonatal follow-up. Methods: We analyzed cases of recent maternal CMV infections confirmed by serological testing at the Department of Obstetrics and Gynecology, Semmelweis University, between 2001 and 2023. In cases of primary CMV infection confirmed by serological testing during pregnancy, we offered amniocentesis at the genetic counseling, which was performed at the 20-21 weeks stage of the pregnancy. Results: In 130 cases of recent maternal CMV infection confirmed by serological testing, amniocentesis was performed, and a total of 11 cases (8.46%) were found to have CMV DNA in the amniotic fluid. Based on the neonatological follow-up examinations in 116 deliveries, 18 newborns had complications (15.52%); however, some cases were associated with multiple complications, resulting in a total of 33 types of complications being identified (28.45%). Among the 11 neurological complications (9.48%), we found 1 case each (0.86%) of severe inoperable intracranial space occupation, hydrocephalus, balance disorder, sleep disorder-sleep apnea, and speech development disorder. Two cases (1.72%) were found to have rigid muscles, epilepsy, and hypotonic muscles. Ophthalmological complications occurred in five cases (4.31%), such as enophthalmos, cataract, and retinopathy of prematurity (ROP), one case each, and two cases of strabism. Other complications were detected in 17 cases (14.66%). Conclusions: Because of the high incidence rate of recent CMV infection, serological testing is recommended following fetal abnormality detected by ultrasound. If a serologically confirmed new infection is diagnosed, the affected couple should be offered amniocentesis. true true 2026 true true true false true false GOLD 2026-05-17 true https://doi.org/10.3390/children12121690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q1 false false false false 2026-01-05T12:48:56.452+0000 Szülészeti és Nőgyógyászati Klinika (SE / AOK / K); Szülészeti és Nőgyógyászati Klinika Baross utca... (SE / AOK / K / SZSZNK) 2 6 2 5 0 true 10073918 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 132592470 /api/authorship/132592470 1 0.2 true false false Author 10096265 /api/author/10096265 Bartek Virág true true Bartek Virag true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 132592471 /api/authorship/132592471 2 0.2 false false false Csire Marta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 132592472 /api/authorship/132592472 3 0.2 false false false Kiss Greta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 132592473 /api/authorship/132592473 4 0.2 false false false Hodula Reka true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 132592474 /api/authorship/132592474 5 0.2 false true true Author 10000568 /api/author/10000568 Beke Artúr true 10000568 true Beke Artur true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 31136844 /api/publicationidentifier/31136844 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/children12121690 https://doi.org/10.3390/children12121690 false true PublicationIdentifier 31136845 /api/publicationidentifier/31136845 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001646247300001 https://www.webofscience.com/wos/woscc/full-record/001646247300001 false true PublicationIdentifier 31349059 /api/publicationidentifier/31349059 PlainSource 111 /api/publicationsource/111 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true ResearchGate publ. https://www.researchgate.net/publication/@@@ true true 111 true GREEN true IDENTICAL 398631461 https://www.researchgate.net/publication/398631461 false true PublicationIdentifier 31136871 /api/publicationidentifier/31136871 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105025916247 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105025916247 false true PublicationIdentifier 31136846 /api/publicationidentifier/31136846 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 41462830 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=41462830&dopt=Abstract false true Classification 12220 /api/classification/12220 true true Keyword 5063 /api/keyword/5063 true 5063 true Keyword 6820 /api/keyword/6820 true 6820 true Keyword 10909 /api/keyword/10909 true 10909 true Keyword 17798 /api/keyword/17798 true 17798 true Keyword 1010233 /api/keyword/1010233 true 1010233 true Keyword 2868413 /api/keyword/2868413 true true SjrRating 11611456 /api/sjrrating/11611456 78 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2735 /api/classificationexternal/2735 true 2735 true Q1 DIRECT true true /api/publication/36849434 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10096265"><a href="/gui2/?type=authors&mode=browse&sel=10096265" target="_blank">Bartek Virag (<span class="authorship-author-name">Bartek Virág</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szülészeti és Nőgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Csire Marta </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kiss Greta </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hodula Reka </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000568"><a href="/gui2/?type=authors&mode=browse&sel=10000568" target="_blank">Beke Artur ✉ (<span class="authorship-author-name">Beke Artúr</span> <span class="authorAux-mtmt"> Genetika, Szülészeti genetika, Szülészet-Nőgyóg...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Szülészeti és Nőgyógyászati Klinika">SZSZNK</span>/Szülészeti és Nőgyógyászati Klinika Baross utcai részleg</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36849434" target="_blank">Associations Between Fetal Symptoms During Pregnancy and Neonatal Clinical Complications with Cytomegalovirus Infection</a></div> <div> <span class="journal-title">CHILDREN (BASEL)</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2227-9067">2227-9067</a>)</span>: <span class="journal-volume">12</span> <span class="journal-issue">12</span> <span class="page"> Paper 1690. 15 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/children12121690" target="_blank" href="https://doi.org/10.3390/children12121690"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001646247300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001646247300001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="398631461" target="_blank" href="https://www.researchgate.net/publication/398631461"> ResearchGate publ. </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105025916247" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105025916247"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="41462830" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=41462830&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pediatrics, Perinatology and Child Health&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36849434</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2026.02.04. 12:19 Kovács Marcell (MTMT Közp., admin) </div> <div class="lockedBy">Központi kezelésű 2026.01.26. 17:13 Kovács Marcell (MTMT Közp., admin) </div> </div></div>