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      <abstractText>Background: Menopause affects every woman worldwide, with varying degrees of severity. In addition to traditional treatments such as hormone replacement therapy, there is also a growing interest in alternative treatments. One possible way to address this need is through the use of placenta extracts. This systematic review is the first to evaluate the efficacy of placental extracts in randomized controlled trials (RCTs). Methods: A systematic search of three databases (MEDLINE, Scopus, Embase) identified studies on placental extract treatment of menopausal symptoms in women, yielding 272 records, with 11 eligible studies. Results: Menopausal severity scores (Kupperman Menopausal Index, Simplified Menopausal Index, Menopausal Rating Scale), somatic and vasomotor symptoms, skin conditions, and certain psychological indicators were significantly improved in the 11 enrolled randomized controlled trials, including perimenopausal and postmenopausal women treated with porcine or human dried, purified placental extract. Placental extract was well tolerated in all studies; no significant side effects or clinically significant laboratory abnormalities were recorded. Conclusions: Porcine and human placental extracts appear to offer potential benefits for alleviating menopausal symptoms.</abstractText>
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      <label>Papp Sára et al. Efficacy and Safety of Placental Extract on Menopausal Symptoms: A Systematic Review. (2025) NUTRIENTS 2072-6643 17 24</label><template>&lt;div class=&quot;JournalArticle Publication short-list&quot;&gt; &lt;div class=&quot;authors&quot;&gt; &lt;span class=&quot;author-name&quot; mtid=&quot;10097345&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10097345&quot; target=&quot;_blank&quot;&gt;Papp, Sára&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10094160&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10094160&quot; target=&quot;_blank&quot;&gt;Tűű, László&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; &gt; Nas, Katalin &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; &gt; Telkes, Zsófia &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10092560&quot;&gt; 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src=&quot;/frontend/resources/grid/publication-core-icon.png&quot;&gt; &lt;div class=&quot;autype autype0&quot;&gt; &lt;span class=&quot;author-name&quot; mtid=&quot;10097345&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10097345&quot; target=&quot;_blank&quot;&gt;Papp Sára (&lt;span class=&quot;authorship-author-name&quot;&gt;Papp Sára&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Orvostudomány&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Szülészeti és Nőgyógyászati Klinika&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10094160&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10094160&quot; target=&quot;_blank&quot;&gt;Tűű László (&lt;span class=&quot;authorship-author-name&quot;&gt;Tűű László&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Belgyógyászat, Endokrinológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; &gt;Nas Katalin &lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; &gt;Telkes Zsófia &lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10092560&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10092560&quot; target=&quot;_blank&quot;&gt;Keszthelyi Lotti (&lt;span class=&quot;authorship-author-name&quot;&gt;Keszthelyi Lotti Lúcia&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Szülészet, nőgyógyászat&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/&lt;span title=&quot;Szülészeti és Nőgyógyászati Klinika&quot;&gt;SZSZNK&lt;/span&gt;/Szülészeti és Nőgyógyászati Klinika Üllői úti részleg&lt;/span&gt; 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&lt;span class=&quot;authorAux-mtmt&quot;&gt; Szülészet-nőgyógyászat&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/&lt;span title=&quot;Szülészeti és Nőgyógyászati Klinika&quot;&gt;SZSZNK&lt;/span&gt;/Szülészeti és Nőgyógyászati Klinika Üllői úti részleg&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10011316&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10011316&quot; target=&quot;_blank&quot;&gt;Várbíró Szabolcs (&lt;span class=&quot;authorship-author-name&quot;&gt;Várbíró Szabolcs&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Keringésélettan&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/&lt;span title=&quot;Szülészeti és Nőgyógyászati Klinika&quot;&gt;SZSZNK&lt;/span&gt;/Szülészeti és Nőgyógyászati Klinika Üllői úti részleg; &lt;span title=&quot;Szegedi Tudományegyetem&quot;&gt;SZTE&lt;/span&gt;/&lt;span title=&quot;Szent-Györgyi Albert Orvostudományi Kar&quot;&gt;SZAOK&lt;/span&gt;/Szülészeti és Nőgyógyászati Klinika&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10056811&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10056811&quot; target=&quot;_blank&quot;&gt;Török Marianna ✉ (&lt;span class=&quot;authorship-author-name&quot;&gt;Török Marianna&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; élettan, szülészet-nőgyógyászat&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/&lt;span title=&quot;Szülészeti és Nőgyógyászati Klinika&quot;&gt;SZSZNK&lt;/span&gt;/Szülészeti és Nőgyógyászati Klinika Üllői úti részleg&lt;/span&gt; &lt;/div&gt; &lt;/div&gt; &lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;36752186&quot; target=&quot;_blank&quot;&gt;Efficacy and Safety of Placental Extract on Menopausal Symptoms: A Systematic Review&lt;/a&gt;&lt;/div&gt; &lt;div&gt; &lt;span class=&quot;journal-title&quot;&gt;NUTRIENTS&lt;/span&gt; &lt;span class=&quot;journal-issn&quot;&gt;( &lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/2072-6643&quot;&gt;2072-6643&lt;/a&gt;)&lt;/span&gt;: &lt;span class=&quot;journal-volume&quot;&gt;17&lt;/span&gt; &lt;span class=&quot;journal-issue&quot;&gt;24&lt;/span&gt; &lt;span class=&quot;page&quot;&gt; Paper 3857. 15 p. &lt;/span&gt; &lt;span class=&quot;year&quot;&gt;(2025)&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;pub-footer&quot;&gt;  &lt;span class=&quot;language&quot; xmlns=&quot;http://www.w3.org/1999/html&quot;&gt;Nyelv: Angol | &lt;/span&gt; &lt;span class=&quot;identifiers&quot;&gt; &lt;span class=&quot;id identifier oa_none&quot; 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PubMed &lt;/a&gt; &lt;/span&gt; &lt;/span&gt; &lt;OnlyViewableByAuthor&gt;&lt;div class=&quot;ratings&quot;&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Food Science&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;D1&lt;/div&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Nutrition and Dietetics&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q1&lt;/div&gt; &lt;/div&gt;&lt;/OnlyViewableByAuthor&gt;   &lt;div class=&quot;mtid&quot;&gt;&lt;span class=&quot;long-pub-mtid&quot;&gt;Közlemény: 36752186&lt;/span&gt; | &lt;span class=&quot;status-data status-VALIDATED&quot;&gt; Egyeztetett &lt;/span&gt; Forrás | &lt;span class=&quot;type-subtype&quot;&gt;Folyóiratcikk ( Összefoglaló cikk ) &lt;/span&gt; | &lt;span class=&quot;pub-category&quot;&gt;Tudományos&lt;/span&gt; | &lt;span class=&quot;publication-sourceOfData&quot;&gt;&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;lastModified&quot;&gt;Utolsó módosítás: 2026.03.24. 13:11 Sass Dávid (SZTE admin5) &lt;/div&gt; 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