In case of a second ipsilateral breast cancer event (2ndiBCE) after primary breast
conserving treatment (BCT), patients are offered salvage mastectomy (SM) or, for selected
patients, 2ndBCT. An international survey dedicated to breast cancer survivors investigated
patients' preferences and expectations.An international survey was drafted jointly
with breast cancer patient advocates from the United States (n = 6) and Europe (n
= 2). The survey was validated with 33 questions divided into four themes: demographic
data, oncological outcomes, patient views and financial issues. The survey was sent
to breast cancer survivors. All information provided was anonymized.From 06/24 to
10/24, 105 patients answered the online survey. The common patient profile was a white
(76 %), married (61.5 %), Christian (58.8 %), US-resident (70.2 %) woman aged between
61 and 70 (62.2 %). Long-term outcomes were perceived as being well established for
SM (51.5 %) and 2ndBCT (17.1 %). Breast re-irradiation was considered at risk of complications
(65.7 %), and 63 % of the patients thought that 2ndBCT provides a more acceptable
body self-image. 2ndBCT was expected to give superior cosmetic outcomes than SM with
breast reconstruction (55.4 %). Having enough information and ample time to consider
the pros and cons of treatment options were very important/important for 99 % and
96.2 %, respectively. Treatment choice was not influenced by financial concerns for
68.3 %.Patient perspective is very important in the decision-making process regarding
salvage treatments. Physicians must provide clear, timely information which will enable
patients to choose the treatment that best meets their expectations.